Brief rapid pacing depresses contractile function via Ca - AJP
... glucose, which were titrated with NaOH to pH 7.35 and bubbled with 100% O2. The internal pipette solution contained (in mM) 120 potassium glutamate, 20 KCl, 1.0 MgCl2, 3 Na2ATP, and 5 HEPES; pH 7.2. Isolation of the L-type Ca2⫹ current (ICa,L) was accomplished by replacing intrapipette K⫹ with cesiu ...
... glucose, which were titrated with NaOH to pH 7.35 and bubbled with 100% O2. The internal pipette solution contained (in mM) 120 potassium glutamate, 20 KCl, 1.0 MgCl2, 3 Na2ATP, and 5 HEPES; pH 7.2. Isolation of the L-type Ca2⫹ current (ICa,L) was accomplished by replacing intrapipette K⫹ with cesiu ...
390K
... observed was very strong, which would not be the case if the target cells were being digested. It seems more reasonable to assume that the large CFB clusters observed corresponded to colonization of senescent or dead dinoflagellate cells by this group of bacteria. This bacterial strategy is common w ...
... observed was very strong, which would not be the case if the target cells were being digested. It seems more reasonable to assume that the large CFB clusters observed corresponded to colonization of senescent or dead dinoflagellate cells by this group of bacteria. This bacterial strategy is common w ...
A unifying model for mTORC1-mediated regulation of mRNA translation Please share
... hyper-dependence on mTOR, we considered the established functions of the 4E-BPs3. A key step in eIF4E-dependent initiation is the cooperative binding of eIF4E and eIF4G1 to mRNA, which nucleates the eIF4F complex26. eIF4G1 also interacts with eIF3, which orchestrates assembly of the 43S pre-initiati ...
... hyper-dependence on mTOR, we considered the established functions of the 4E-BPs3. A key step in eIF4E-dependent initiation is the cooperative binding of eIF4E and eIF4G1 to mRNA, which nucleates the eIF4F complex26. eIF4G1 also interacts with eIF3, which orchestrates assembly of the 43S pre-initiati ...
Growth factors and tooth development
... adult mammals is the liver. Besides the yolk sac. which is the ...
... adult mammals is the liver. Besides the yolk sac. which is the ...
chapt 4
... Allow large molecules like RNA to pass through the membrane into the cytoplasm Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
... Allow large molecules like RNA to pass through the membrane into the cytoplasm Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
Deep Insight Section DNA Double-Strand Breaks Atlas of Genetics and Cytogenetics
... tract of heteroduplex DNA (i.e., that which contains one single strand from each of the two recombining duplexes). Sequence differences in heteroduplex DNA created by strand invasion or by branch migration can be corrected by the mismatch repair (MMR) system, which also functions in the repair of mi ...
... tract of heteroduplex DNA (i.e., that which contains one single strand from each of the two recombining duplexes). Sequence differences in heteroduplex DNA created by strand invasion or by branch migration can be corrected by the mismatch repair (MMR) system, which also functions in the repair of mi ...
Somatic Cytokinesis and Pollen Maturation in Arabidopsis
... types of pollen grains. Fifty percent of the pollen grains had a normal ellipsoidal morphology and fluoresced homogenously (Figure 2B). The other half of the pollen grains showed random deposits of material that was not stained by PI (Figures 2C and 2D). In severely affected pollen with a shriveled ...
... types of pollen grains. Fifty percent of the pollen grains had a normal ellipsoidal morphology and fluoresced homogenously (Figure 2B). The other half of the pollen grains showed random deposits of material that was not stained by PI (Figures 2C and 2D). In severely affected pollen with a shriveled ...
Early Development and Axis Formation in Amphibians
... Determination of Ectoderm Early gastrulation stage cells are uncommitted - exhibit regulative development ...
... Determination of Ectoderm Early gastrulation stage cells are uncommitted - exhibit regulative development ...
PROTEIN DEPHOSPHORYLATION AND THE INTRACELLULAR
... was quickly suggested that PP1 and PP2A might be tumor suppressors in their own right (6). These exciting discoveries occurred a short time after we learned that many oncogenes encode protein kinases, and, more specifically, that the enzyme responsible for triggering entry into mitosis, p34cdc2/CDC2 ...
... was quickly suggested that PP1 and PP2A might be tumor suppressors in their own right (6). These exciting discoveries occurred a short time after we learned that many oncogenes encode protein kinases, and, more specifically, that the enzyme responsible for triggering entry into mitosis, p34cdc2/CDC2 ...
On the Morphology of the Drosophila Heart
... Cardiomyocytes are cells with easily distinguishable functionalities form the heart tube; these are the contractile cardiomyocytes discussed in this Section (4.1), the ostia (4.2) and the intracardiac valve cells (4.3). Differentiation into different cells types is achieved early during embryogenesi ...
... Cardiomyocytes are cells with easily distinguishable functionalities form the heart tube; these are the contractile cardiomyocytes discussed in this Section (4.1), the ostia (4.2) and the intracardiac valve cells (4.3). Differentiation into different cells types is achieved early during embryogenesi ...
Stimulation of Cell Elongation by Tetraploidy in Hypocotyls of Dark
... Endopolyploidy, which is essential for angiosperm development, is controlled by an endoreduplication cycle whereby the genome is duplicated without cellular division. Conversely, autopolyploidy arises spontaneously or experimentally through the production of a 2n gamete during reproduction [3]. The ...
... Endopolyploidy, which is essential for angiosperm development, is controlled by an endoreduplication cycle whereby the genome is duplicated without cellular division. Conversely, autopolyploidy arises spontaneously or experimentally through the production of a 2n gamete during reproduction [3]. The ...
structural responses of amoebae
... some vesicles outside the membrane-delimited spaces at 6 h, which suggests that not all the injected cytoplasm had been segregated from that of the host by this time after the operation. Thoria was not observed in large vacuoles identified as old food vacuoles on the basis of their size, polymorphou ...
... some vesicles outside the membrane-delimited spaces at 6 h, which suggests that not all the injected cytoplasm had been segregated from that of the host by this time after the operation. Thoria was not observed in large vacuoles identified as old food vacuoles on the basis of their size, polymorphou ...
hospital/institute/center - Advances in Inflammatory Bowel Diseases
... neutrophil infiltration into the epithelium ...
... neutrophil infiltration into the epithelium ...
Muscle Development in Drosophila
... muscle forming germ layer, the mesoderm. From the mesoderm originate different muscles, each one distinct in its shape, size, attachment and innervation. Muscles achieve their unique identities by utilising genetic information that is common to the development of all muscles as well as specialised i ...
... muscle forming germ layer, the mesoderm. From the mesoderm originate different muscles, each one distinct in its shape, size, attachment and innervation. Muscles achieve their unique identities by utilising genetic information that is common to the development of all muscles as well as specialised i ...
Basophils and Autoreactive IgE in the Pathogenesis of
... Since Lyn is not expressed in T cells, our initial bias was that mast cells might be driving this unexpected Th2 skewing in Lyn-/- mice. To test this possibility, mast cell deficient mice (Kitw-sh/w-sh) were crossed to Lyn-/- mice. However, the resulting mice (Kitw-sh/w-sh Lyn-/-) showed no alterati ...
... Since Lyn is not expressed in T cells, our initial bias was that mast cells might be driving this unexpected Th2 skewing in Lyn-/- mice. To test this possibility, mast cell deficient mice (Kitw-sh/w-sh) were crossed to Lyn-/- mice. However, the resulting mice (Kitw-sh/w-sh Lyn-/-) showed no alterati ...
Amphibian gastrulation: history and evolution of a 125 year
... Haeckel is widely known as a prominent early supporter of Darwin’s evolutionist theory. In the late 1860s, he was trying to draw a phyletic tree of the animal and vegetal kingdoms and was especially interested in embryological comparisons between different phyla, inasmuch as they shared similar embr ...
... Haeckel is widely known as a prominent early supporter of Darwin’s evolutionist theory. In the late 1860s, he was trying to draw a phyletic tree of the animal and vegetal kingdoms and was especially interested in embryological comparisons between different phyla, inasmuch as they shared similar embr ...
Gene Section PTPRJ (protein tyrosine phosphatase, receptor type, J)
... recruitment, thus impacting specifically on phosphoTyr204 ERK1/2 dephosphorylation efficiency. DEP-1 can therefore suppress proliferation by sequestering ERK1/2, irrespective of ERK1/2 phosphorylation state and by dephosphorylating the ERK1/2 activation loop. Loss of heterozygosity, and missense mut ...
... recruitment, thus impacting specifically on phosphoTyr204 ERK1/2 dephosphorylation efficiency. DEP-1 can therefore suppress proliferation by sequestering ERK1/2, irrespective of ERK1/2 phosphorylation state and by dephosphorylating the ERK1/2 activation loop. Loss of heterozygosity, and missense mut ...
IL-10–producing NKT10 cells are a distinct regulatory invariant
... agonist of mouse and human iNKT cells, has been tested in clinical trials for the treatment of cancer patients, and it is under continuing development as a therapeutic agent (1–7). The influence of iNKT cells can, however, be unpredictable, and they may exhibit opposing effects on tumor growth, infl ...
... agonist of mouse and human iNKT cells, has been tested in clinical trials for the treatment of cancer patients, and it is under continuing development as a therapeutic agent (1–7). The influence of iNKT cells can, however, be unpredictable, and they may exhibit opposing effects on tumor growth, infl ...
Intracellular Signals Direct Integrin Localization to Sites of Function
... to that ligand is found in the focal adhesions while the other integrin is found distributed diffusely over the cell surface (e.g., Fath et al., 1989). Third, when integrins bind to extracellular ligands, they become clustered, which by itself induces increased tyrosine phosphorylation of intracellu ...
... to that ligand is found in the focal adhesions while the other integrin is found distributed diffusely over the cell surface (e.g., Fath et al., 1989). Third, when integrins bind to extracellular ligands, they become clustered, which by itself induces increased tyrosine phosphorylation of intracellu ...
384 The non-canonical Wnt ligand, Wnt4, is highly expressed in
... The non-canonical Wnt ligand, Wnt4, is highly expressed in pancreatic beta cells and its expression is negatively correlated with cell growth H.J. Welters, A. Henderson, A. Bowen; Institute of Biomedical and Clinical Science, University of Exeter Medical School, UK. Background and aims: We have prev ...
... The non-canonical Wnt ligand, Wnt4, is highly expressed in pancreatic beta cells and its expression is negatively correlated with cell growth H.J. Welters, A. Henderson, A. Bowen; Institute of Biomedical and Clinical Science, University of Exeter Medical School, UK. Background and aims: We have prev ...
Agriculturae Conspectus Scientificus
... 3A and 3C). The callose deposits were quite abundant in cell walls of idioblasts (Figs 3B and 3D). No visible differences in callose deposits between idioblasts walls in spongy parenchyma of both cultivars were noticed, but there were significant differences (p < 0.05) in number of idioblasts per cr ...
... 3A and 3C). The callose deposits were quite abundant in cell walls of idioblasts (Figs 3B and 3D). No visible differences in callose deposits between idioblasts walls in spongy parenchyma of both cultivars were noticed, but there were significant differences (p < 0.05) in number of idioblasts per cr ...
Actin Dynamics in Papilla Cells of Brassica rapa
... and number of large peaks increased (Fig. 1, B and C). In contrast, during self-pollination, a large peak was not detected and the number of small peaks also decreased (Fig. 1, D and E). These quantitative results are consistent with the data shown in Figure 1. We next randomly selected 50 papilla c ...
... and number of large peaks increased (Fig. 1, B and C). In contrast, during self-pollination, a large peak was not detected and the number of small peaks also decreased (Fig. 1, D and E). These quantitative results are consistent with the data shown in Figure 1. We next randomly selected 50 papilla c ...
Cell Wall Loosening by Expansins
... acid-induced extension. We focused our initial biochemical studies of wall extension on the cell wall of cucumber hypocotyls, which can extend for many hours when clamped at acid pH (Cosgrove, 1989). Because the cells are dead when they are clamped in the extensometer, this wall extension occurs wit ...
... acid-induced extension. We focused our initial biochemical studies of wall extension on the cell wall of cucumber hypocotyls, which can extend for many hours when clamped at acid pH (Cosgrove, 1989). Because the cells are dead when they are clamped in the extensometer, this wall extension occurs wit ...