BI475 Ch15 SQ
... 8. Discuss the impact of gene duplication on the evolution of the homeotic selector genes of eukaryotes. 9. Define the term ‘concerted evolution' and state why this process is important in the evolution of some multigene families. 10. Describe, with examples, the processes of domain duplication and ...
... 8. Discuss the impact of gene duplication on the evolution of the homeotic selector genes of eukaryotes. 9. Define the term ‘concerted evolution' and state why this process is important in the evolution of some multigene families. 10. Describe, with examples, the processes of domain duplication and ...
Genetic Markers
... is on each side of the disease gene. Then you would know that the disease gene must be in the candidate region of the genome between the two markers, a few million bases of DNA. ...
... is on each side of the disease gene. Then you would know that the disease gene must be in the candidate region of the genome between the two markers, a few million bases of DNA. ...
Lecture 32 Slides
... 1 Transformation: uptake of DNA from environment 2 Transduction: DNA transfer by viruses 3 Conjugation: plasmid transfer between bacterial cells ...
... 1 Transformation: uptake of DNA from environment 2 Transduction: DNA transfer by viruses 3 Conjugation: plasmid transfer between bacterial cells ...
Table S1.
... We infer homology between two or more proteins by detecting similar regions in the amino acid sequences when aligned. A great similarity between two proteins indicates, in general, they have the ...
... We infer homology between two or more proteins by detecting similar regions in the amino acid sequences when aligned. A great similarity between two proteins indicates, in general, they have the ...
Using microsatellites as molecular markers
... Using microsatellites as molecular markers Use PCR primers that are complementary to single copy sequences flanking microsatellites to amplify microsatellite-containing region. Depending on number of microsatellite repeats, will get different lengths PCR products (many different possible alleles, n ...
... Using microsatellites as molecular markers Use PCR primers that are complementary to single copy sequences flanking microsatellites to amplify microsatellite-containing region. Depending on number of microsatellite repeats, will get different lengths PCR products (many different possible alleles, n ...
Human genomics
... • Bioinformatics is the use of computer technology to identify DNA sequences. • Systematics compares human genome sequence data and genomes of other species to provide information on evolutionary relationships and origins. • Personalised medicine is based on an individual’s genome. Analysis of an in ...
... • Bioinformatics is the use of computer technology to identify DNA sequences. • Systematics compares human genome sequence data and genomes of other species to provide information on evolutionary relationships and origins. • Personalised medicine is based on an individual’s genome. Analysis of an in ...
Genetic and Genomics: An Introduction
... the female), each gamete may not carry the exact same DNA sequence, i.e., a polymorphism (poly = many, morph = form) may occur which involves one of two or more variants of a particular DNA sequence. The most common polymorphism involves variation at a single base pair. This variation is called a si ...
... the female), each gamete may not carry the exact same DNA sequence, i.e., a polymorphism (poly = many, morph = form) may occur which involves one of two or more variants of a particular DNA sequence. The most common polymorphism involves variation at a single base pair. This variation is called a si ...
DNA Replication
... individual genes in isolation and their role in inheritance e.g. "monogenic" diseases such as sickle cell anemia and cystic fibrosis, caused by an error in a single gene. ...
... individual genes in isolation and their role in inheritance e.g. "monogenic" diseases such as sickle cell anemia and cystic fibrosis, caused by an error in a single gene. ...
E. coli
... sequence of the genome of an organism, and the identification of all its genes • Genome projects are possible because of the large-scale, automated application of molecular genetic techniques (cloning and sequencing) • There are now complete genome projects for all major groups of organism ...
... sequence of the genome of an organism, and the identification of all its genes • Genome projects are possible because of the large-scale, automated application of molecular genetic techniques (cloning and sequencing) • There are now complete genome projects for all major groups of organism ...
encode 2012
... regions; this number is at least as large as those that lie in protein-coding genes. • Single nucleotide polymorphisms (SNPs) associated with disease by GWAS are enriched within non-coding functional elements, with a majority residing in or near ENCODE-defined regions that are outside of protein-cod ...
... regions; this number is at least as large as those that lie in protein-coding genes. • Single nucleotide polymorphisms (SNPs) associated with disease by GWAS are enriched within non-coding functional elements, with a majority residing in or near ENCODE-defined regions that are outside of protein-cod ...
Modifier genes in Huntington`s desease - Ruhr
... disease duration, CAG repeat length or any other genotype. ...
... disease duration, CAG repeat length or any other genotype. ...
2D Barcode Quiz
... Proteins are polymers consisting of building blocks called amino acids All proteins begin with the amino acid Methionine A codon is a series of four sequential nucleotides which codes for an amino acid Polymerase is an enzyme which breaks down DNA molecules Transcription is the process of making an ...
... Proteins are polymers consisting of building blocks called amino acids All proteins begin with the amino acid Methionine A codon is a series of four sequential nucleotides which codes for an amino acid Polymerase is an enzyme which breaks down DNA molecules Transcription is the process of making an ...
TRANSPONSONS or TRANSPOSABLE ELEMENTS
... TRANSPONSONS or TRANSPOSABLE ELEMENTS A talk by Dr Paul Kalitsis on 23/8/07 These are some notes taken whilst view the PowerPoint presentation and some may be of assistance in filling the gaps. Barbara McLintock (1940s) was the founder of “jumping genes” which led to the discovery of transposable el ...
... TRANSPONSONS or TRANSPOSABLE ELEMENTS A talk by Dr Paul Kalitsis on 23/8/07 These are some notes taken whilst view the PowerPoint presentation and some may be of assistance in filling the gaps. Barbara McLintock (1940s) was the founder of “jumping genes” which led to the discovery of transposable el ...
This examination paper consists of 4 pages
... Do not integrate their DNA into the host genome Carry a reverse transcriptase inside their capsid Have a typical genome of 3000 nucleotides in size 2. Prokaryotic genomes Contain operons Are usually larger than 5x109 bp Do not harbor any transposons Are packaged into nucleoids Exist normally in two ...
... Do not integrate their DNA into the host genome Carry a reverse transcriptase inside their capsid Have a typical genome of 3000 nucleotides in size 2. Prokaryotic genomes Contain operons Are usually larger than 5x109 bp Do not harbor any transposons Are packaged into nucleoids Exist normally in two ...
Disorders associated with mutations in the POLG gene
... Case 2: SO – DNA results (contd) • p.T914P & p.R627W are previously reported mutations • Compound heterozygosity confirmed by testing the ...
... Case 2: SO – DNA results (contd) • p.T914P & p.R627W are previously reported mutations • Compound heterozygosity confirmed by testing the ...
Nuclear genome 1
... Genetic Redundancy • The sizes of many gene families have increased much more in certain organisms. • May account for much of the unexpectedly high genetic complexity of angiosperms ...
... Genetic Redundancy • The sizes of many gene families have increased much more in certain organisms. • May account for much of the unexpectedly high genetic complexity of angiosperms ...
Mitochondrial DNA Analysis
... • Sperm donates only nucleus to zygote • Therefore, all mitochondria are inherited from mother only – No recombination – No paternal contribution ...
... • Sperm donates only nucleus to zygote • Therefore, all mitochondria are inherited from mother only – No recombination – No paternal contribution ...
Plant Nuclear Genome Size Variation
... Aneuploid variation – gain or less of one or more chromosomes ...
... Aneuploid variation – gain or less of one or more chromosomes ...
2nd problem set
... template, primer, millions of ACGT nucleotides and millions of dideoxyC nucleotides. (p. 387-393 of your textbook has a good review if you are having trouble) a) How many different lengths of DNA strands will be represented in your tube? (Assume that there are millions of each of them because you ra ...
... template, primer, millions of ACGT nucleotides and millions of dideoxyC nucleotides. (p. 387-393 of your textbook has a good review if you are having trouble) a) How many different lengths of DNA strands will be represented in your tube? (Assume that there are millions of each of them because you ra ...
No Slide Title
... The DNA sequence of the entire haploid set of chromosomes constitutes the genome of an organism (and, more broadly, species). The sequence of many genomes has been (many bacteria, yeast, C. elegans, Drosophila melanogaster, human) or is being (mouse, maize) determined. WHY do we want to determine ge ...
... The DNA sequence of the entire haploid set of chromosomes constitutes the genome of an organism (and, more broadly, species). The sequence of many genomes has been (many bacteria, yeast, C. elegans, Drosophila melanogaster, human) or is being (mouse, maize) determined. WHY do we want to determine ge ...
pdf format publicity flyer for the proceedings
... mitochondria and their bacterial homologues: New perspectives on symbiosis in cell evolution Compiled and edited by John Raven and John Allen To be published January 2003: Special offer price: £45 (usual price: £85) Chloroplasts and mitochondria are energy-converting organelles of eukaryotic cells. ...
... mitochondria and their bacterial homologues: New perspectives on symbiosis in cell evolution Compiled and edited by John Raven and John Allen To be published January 2003: Special offer price: £45 (usual price: £85) Chloroplasts and mitochondria are energy-converting organelles of eukaryotic cells. ...
... the genome. Since the last century the replicon model has been proposed in order to explain the general mechanism of genome duplication in bacteria. Later work in yeast lead to identifying proteins and dna sequences that participate in the initiation of replication in a similar fashion to what has b ...