A Lectin with Highly Potent Inhibitory Activity toward Breast
... many Japanese cuisines. Some of the tubers were utilized in traditional Chinese medicine, revealing their therapeutic potentials [21]. Although hemagglutinating activity was found in some types of yam tubers, there were very few investigations on the yam lectins. Also, none of the studies involving ...
... many Japanese cuisines. Some of the tubers were utilized in traditional Chinese medicine, revealing their therapeutic potentials [21]. Although hemagglutinating activity was found in some types of yam tubers, there were very few investigations on the yam lectins. Also, none of the studies involving ...
Erythropoietin critically regulates the terminal
... to wild-type littermate controls (Figure 5C). While Epornull primitive erythroblasts exhibit an advanced maturation phenotype at E10.5, they continue to mature as evidenced by the progressive reduction in cell size, nuclear size, RNA content, CD71 cell surface expression (Figure 5C), and mitochondri ...
... to wild-type littermate controls (Figure 5C). While Epornull primitive erythroblasts exhibit an advanced maturation phenotype at E10.5, they continue to mature as evidenced by the progressive reduction in cell size, nuclear size, RNA content, CD71 cell surface expression (Figure 5C), and mitochondri ...
Introduction Wnt signaling in development
... that controls its stability. In the absence of Wnt signaling, this complex, which consists of the scaffolding protein Axin, the tumor suppressor gene product APC and the protein kinases Casein kinase Iα and GSK3β, targets β-catenin for ubiquitination and degradation by the proteasome. Binding of Wnt ...
... that controls its stability. In the absence of Wnt signaling, this complex, which consists of the scaffolding protein Axin, the tumor suppressor gene product APC and the protein kinases Casein kinase Iα and GSK3β, targets β-catenin for ubiquitination and degradation by the proteasome. Binding of Wnt ...
Metabolism of Tac - The Journal of Experimental Medicine
... studies. It exists in vivo as a transmembrane complete molecule (TM-Tac) on cell surfaces and as a truncated soluble form (sTac; slL2Rot), sTac has been used as a serum marker o f T cell activation in immune disorders and of tumor burden in Tac-expressing malignancies. In vivo, serum levels o f all ...
... studies. It exists in vivo as a transmembrane complete molecule (TM-Tac) on cell surfaces and as a truncated soluble form (sTac; slL2Rot), sTac has been used as a serum marker o f T cell activation in immune disorders and of tumor burden in Tac-expressing malignancies. In vivo, serum levels o f all ...
Desmin Is Essential for the Tensile Strength and
... Morphological data have suggested that desmin filaments are implicated in muscle resistance, and it has been predicted that intermediate filaments may elongate locally if sarcomeres lose the ability to generate and transmit active force. In such a case, desmin may serve as a relay in transmitting te ...
... Morphological data have suggested that desmin filaments are implicated in muscle resistance, and it has been predicted that intermediate filaments may elongate locally if sarcomeres lose the ability to generate and transmit active force. In such a case, desmin may serve as a relay in transmitting te ...
The Hype on the Endothelin Signaling System Muscarinic Receptor
... the accumulation of glial fibrillary acidic protein (GFAP) is observed. Although this type of cellular response has probably evolved to limit neuronal damage, excessive activation of Muller cells can impair recovery19,20. The activation of Muller cells in response to diverse retinal disorders sugges ...
... the accumulation of glial fibrillary acidic protein (GFAP) is observed. Although this type of cellular response has probably evolved to limit neuronal damage, excessive activation of Muller cells can impair recovery19,20. The activation of Muller cells in response to diverse retinal disorders sugges ...
Full Text - Labs / Projects - Fred Hutchinson Cancer Research Center
... Members of the Rho family of small GTPases have been shown to be important regulators of cellular behavior, especially actin cytoskeletal organization and acto-myosin based contractility (Hall, 1998). Rho proteins function as molecular switches, cycling between an active GTP-bound state and an inact ...
... Members of the Rho family of small GTPases have been shown to be important regulators of cellular behavior, especially actin cytoskeletal organization and acto-myosin based contractility (Hall, 1998). Rho proteins function as molecular switches, cycling between an active GTP-bound state and an inact ...
thesis - BORA
... 1995). Genetic screening of zebrafish (Danio rerio) mutants has identified several genes that are involved in the specification, including bozozok/boz and flh, and differentiation of the notochord, such as no tail/ntl and genes encoding laminins and coatomers (Amacher and Kimmel, 1998; Coutinho et a ...
... 1995). Genetic screening of zebrafish (Danio rerio) mutants has identified several genes that are involved in the specification, including bozozok/boz and flh, and differentiation of the notochord, such as no tail/ntl and genes encoding laminins and coatomers (Amacher and Kimmel, 1998; Coutinho et a ...
Pistil Factors Controlling Pollination
... interaction on a dry stigma is the self-incompatibility response in Brassica. Its components constitute the male determinant S-locus cystein rich protein, the S-locus glycoprotein female determinant secreted by the stigma into the cell wall, the S-locus receptor kinase located in the stigmatic plasm ...
... interaction on a dry stigma is the self-incompatibility response in Brassica. Its components constitute the male determinant S-locus cystein rich protein, the S-locus glycoprotein female determinant secreted by the stigma into the cell wall, the S-locus receptor kinase located in the stigmatic plasm ...
Microtubule Independent Vesiculation of Golgi Membranes and the
... Golgi membranes completely into small vesicles (VGMs for vesiculated Golgi membranes) as revealed by both, electron microscopy and light microscopy (Takizawa et al., 1993). Upon removal of the drug the Golgi membranes reassemble rapidly into the pericentriolar region of the cell. This process is obs ...
... Golgi membranes completely into small vesicles (VGMs for vesiculated Golgi membranes) as revealed by both, electron microscopy and light microscopy (Takizawa et al., 1993). Upon removal of the drug the Golgi membranes reassemble rapidly into the pericentriolar region of the cell. This process is obs ...
Structure and function of the notochord: an essential
... become ossified in a fashion similar to cartilage. Consistent with this view, in mutant mice that lack type II collagen, the notochord is not replaced by bone, presumably because the type II collagen network is required for proper deposition of type X collagen. Evolutionary origins of the notochord ...
... become ossified in a fashion similar to cartilage. Consistent with this view, in mutant mice that lack type II collagen, the notochord is not replaced by bone, presumably because the type II collagen network is required for proper deposition of type X collagen. Evolutionary origins of the notochord ...
Costes et al.
... interactions, which does not have the limitations of the above methods, but still requires live samples. It evaluates binding kinetics of a protein by measuring the rate of fluorescence recovery after photobleaching (McNally et al., 2000) and interpreting slow recovery as the signature of bound prot ...
... interactions, which does not have the limitations of the above methods, but still requires live samples. It evaluates binding kinetics of a protein by measuring the rate of fluorescence recovery after photobleaching (McNally et al., 2000) and interpreting slow recovery as the signature of bound prot ...
AcmA of Lactococcus lactis is an N-acetylglucosaminidase
... for cell separation and autolysis of cells Several mutant AcmA derivatives were constructed to investigate the function of the three LysM domains in the C-terminus of AcmA. Because expression of AcmA in Escherichia coli results in growth problems followed by severe lysis [3], cloning and expression ...
... for cell separation and autolysis of cells Several mutant AcmA derivatives were constructed to investigate the function of the three LysM domains in the C-terminus of AcmA. Because expression of AcmA in Escherichia coli results in growth problems followed by severe lysis [3], cloning and expression ...
Chromosome Segregation in Budding Yeast: Sister Chromatid
... form a ring-like structure in vitro led to the “embrace” model for cohesion (Haering et al. 2002). This model proposes that cohesion is the result of topologically embracing the two sister DNA molecules within a cohesin ring and that opening of the ring, due to cleavage of its Scc1 subunit by separa ...
... form a ring-like structure in vitro led to the “embrace” model for cohesion (Haering et al. 2002). This model proposes that cohesion is the result of topologically embracing the two sister DNA molecules within a cohesin ring and that opening of the ring, due to cleavage of its Scc1 subunit by separa ...
Golgins and GTPases, giving identity and structure to the Golgi
... the extreme C-terminus of GM130 [27]. Giantin, on the other hand, is an integral membrane protein of 400 kDa, with a C-terminal transmembrane domain and a very large cytoplasmic domain containing extensive regions predicted to form coiled-coil [28]. It is localized to the edges of the Golgi stack an ...
... the extreme C-terminus of GM130 [27]. Giantin, on the other hand, is an integral membrane protein of 400 kDa, with a C-terminal transmembrane domain and a very large cytoplasmic domain containing extensive regions predicted to form coiled-coil [28]. It is localized to the edges of the Golgi stack an ...
Biological Properties and Characterization of Lectin from Red
... Lectins bind carbohydrates reversibly and non-covalently, detecting subtle differences in their complex structure.(21) According to their carbohydrate specificity, they can broadly be divided into those that bind monosaccharides, as well as oligosaccharides and those that recognize oligosaccharides ...
... Lectins bind carbohydrates reversibly and non-covalently, detecting subtle differences in their complex structure.(21) According to their carbohydrate specificity, they can broadly be divided into those that bind monosaccharides, as well as oligosaccharides and those that recognize oligosaccharides ...
Can muscle regeneration fail in chronic inflammation: a weakness in
... muscle fibres through a myocytotoxic effect of infiltrating inflammatory cells [6]. Muscle tissue in polymyositis, dermatomyositis and IBM is typically characterized by infiltration of inflammatory cells; in particular, of T cells, macrophages, dendritic cells and occasionally B cells [2, 13]. The T ...
... muscle fibres through a myocytotoxic effect of infiltrating inflammatory cells [6]. Muscle tissue in polymyositis, dermatomyositis and IBM is typically characterized by infiltration of inflammatory cells; in particular, of T cells, macrophages, dendritic cells and occasionally B cells [2, 13]. The T ...
interstitial cells: regulators of smooth muscle function
... I. INTRODUCTION “Interstitial cells” is a morphological term denoting a variety of cells of differing origins and phenotypes occupying spaces within the interstitium between the cells most prominent in defining a given tissue. In smooth muscle tissues fibroblasts, mast cells, macrophages, and inters ...
... I. INTRODUCTION “Interstitial cells” is a morphological term denoting a variety of cells of differing origins and phenotypes occupying spaces within the interstitium between the cells most prominent in defining a given tissue. In smooth muscle tissues fibroblasts, mast cells, macrophages, and inters ...
Microtubules Contribute to Tubule Elongation and
... The endoplasmic reticulum (ER) is a network of tubules and sheet-like structures in eukaryotic cells. Some ER tubules dynamically change their morphology, and others form stable structures. In plants, it has been thought that the ER tubule extension is driven by the actin-myosin machinery. Here, we ...
... The endoplasmic reticulum (ER) is a network of tubules and sheet-like structures in eukaryotic cells. Some ER tubules dynamically change their morphology, and others form stable structures. In plants, it has been thought that the ER tubule extension is driven by the actin-myosin machinery. Here, we ...
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... factors, or whether it does possess unique tissue-specific activity relevant to the in vivo control of the onset of somite chondrogenesis. Demonstration of specificity (or lack of specificity) in the activity of the spinal cord is relevant to an assessment of the morphogenetic significance of in vit ...
... factors, or whether it does possess unique tissue-specific activity relevant to the in vivo control of the onset of somite chondrogenesis. Demonstration of specificity (or lack of specificity) in the activity of the spinal cord is relevant to an assessment of the morphogenetic significance of in vit ...
CELLS - Hudson City School District
... Largest structure in a plant cell Smaller in animal cells ...
... Largest structure in a plant cell Smaller in animal cells ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).