
the genetics of the budgerigar
... fixative solution, such as formalin, which kills without destruction or distortion, and then stains it by immersing it in various solutions of dyestuffs. Since different structures take up the different stains in varying degrees, when such a preparation is examined under the microscope, one can see ...
... fixative solution, such as formalin, which kills without destruction or distortion, and then stains it by immersing it in various solutions of dyestuffs. Since different structures take up the different stains in varying degrees, when such a preparation is examined under the microscope, one can see ...
Tufts` Canine and Feline Breeding and Genetics Conference
... Because of the increased awareness of breeders, pet owners, and veterinarians of genetic defects and the improved diagnostic abilities in clinical practice, the number of reported hereditary diseases in small animals is rapidly growing. While in humans around five thousand disorders have been descri ...
... Because of the increased awareness of breeders, pet owners, and veterinarians of genetic defects and the improved diagnostic abilities in clinical practice, the number of reported hereditary diseases in small animals is rapidly growing. While in humans around five thousand disorders have been descri ...
Reciprocal deletion and duplication at 2q23.1 indicates a
... syndrome. We provide data to support MBD5 as the critical gene for both 2q23.1 deletion and duplication syndromes and demonstrate that appropriate dosage of MBD5 is critical for normal development. Refinement of the 2q23.1 duplication syndrome critical region Given the establishment of MBD5 haploins ...
... syndrome. We provide data to support MBD5 as the critical gene for both 2q23.1 deletion and duplication syndromes and demonstrate that appropriate dosage of MBD5 is critical for normal development. Refinement of the 2q23.1 duplication syndrome critical region Given the establishment of MBD5 haploins ...
Detection of mcr-1 colistin resistance gene in
... MDR E. coli isolates [3,5-7]. Technical variability among methods for colistin susceptibility testing is notorious ...
... MDR E. coli isolates [3,5-7]. Technical variability among methods for colistin susceptibility testing is notorious ...
Leaf shape: genetic controls and environmental factors
... and is represented by leaves of most model plants, including Arabidopsis, Antirrhinum majus L. and Zea mays L. Simple leaves show more or less serration in the margin but are not separated into several units. On the other hand, tomato, rose and white clover are typical species with compound leaves, ...
... and is represented by leaves of most model plants, including Arabidopsis, Antirrhinum majus L. and Zea mays L. Simple leaves show more or less serration in the margin but are not separated into several units. On the other hand, tomato, rose and white clover are typical species with compound leaves, ...
Agarose Gel Electrophoresis
... Monitoring and interpreting separations of DNA through agarose gels The DNA sample. In choosing the amount of DNA to be loaded, the width of the well plus the depth of the gel and the number and size of DNA fragments should be considered. Between 5 and 200 ng of a single DNA fragment can be loaded i ...
... Monitoring and interpreting separations of DNA through agarose gels The DNA sample. In choosing the amount of DNA to be loaded, the width of the well plus the depth of the gel and the number and size of DNA fragments should be considered. Between 5 and 200 ng of a single DNA fragment can be loaded i ...
View PDF - G3: Genes | Genomes | Genetics
... them. Notably, the mat1 marker in this cross was recorded by the replica-plating and iodine-staining procedure employed for research with S. pombe. Nuclei orientation is indeterminate in the S. japonicus meiosis Interestingly, the two spores at each end of the ascus are “sisters” in the linear four- ...
... them. Notably, the mat1 marker in this cross was recorded by the replica-plating and iodine-staining procedure employed for research with S. pombe. Nuclei orientation is indeterminate in the S. japonicus meiosis Interestingly, the two spores at each end of the ascus are “sisters” in the linear four- ...
Distribution of orphan metabolic activities
... species, over half of orphan reactions have been experimentally characterized in more than one organism. Shrinking the space of orphan activities will likely require a close collaboration between computational and experimental laboratories. Introduction Rapid technological progress, spurred by genom ...
... species, over half of orphan reactions have been experimentally characterized in more than one organism. Shrinking the space of orphan activities will likely require a close collaboration between computational and experimental laboratories. Introduction Rapid technological progress, spurred by genom ...
Journal Club 3
... • Heme binds to NO and O2; competitive inhibitor • Cyanide: heme-protein inhibitor • Found to block dormancy regulon gene expression without affecting overall transcription levels • Indicates that a heme-containing protein is likely to be a component of the NO/low O2 signal transduction system ...
... • Heme binds to NO and O2; competitive inhibitor • Cyanide: heme-protein inhibitor • Found to block dormancy regulon gene expression without affecting overall transcription levels • Indicates that a heme-containing protein is likely to be a component of the NO/low O2 signal transduction system ...
Development and characterization of DehaloR^2, a novel anaerobic
... strains of Dehalococcoides sp. are the only identified bacteria to date capable of performing complete dechlorination to ethene (Taş et al. 2009). Previously reported chlorinated ethene-respiring microbial consortia studied in marine sediment microcosms were distinct from those obtained from soil an ...
... strains of Dehalococcoides sp. are the only identified bacteria to date capable of performing complete dechlorination to ethene (Taş et al. 2009). Previously reported chlorinated ethene-respiring microbial consortia studied in marine sediment microcosms were distinct from those obtained from soil an ...
The daily rhythm of mice
... of genetically modified adeno-associated viruses [19]. Tissue-specific knock out mice of the Bmal1 gene in the liver had no functional oscillator in this tissue [20]. In addition, the glucose metabolism in the liver was disturbed. Consequently, these mice exhibited time-restricted hypoglycemia on the ...
... of genetically modified adeno-associated viruses [19]. Tissue-specific knock out mice of the Bmal1 gene in the liver had no functional oscillator in this tissue [20]. In addition, the glucose metabolism in the liver was disturbed. Consequently, these mice exhibited time-restricted hypoglycemia on the ...
Development of a repressible mycobacterial
... them during experimental infection (7–9). Even though these tools proved to be quite useful, they have the disadvantage that Tc functions as an inducer of gene expression and has therefore to be removed to silence the gene under investigation. For this reason Guo et al. (13) developed a modified syst ...
... them during experimental infection (7–9). Even though these tools proved to be quite useful, they have the disadvantage that Tc functions as an inducer of gene expression and has therefore to be removed to silence the gene under investigation. For this reason Guo et al. (13) developed a modified syst ...
Biochemistry Lecture 23 THE LAST ONE!
... specific site on subunit • Called P site (for “Peptidyl” site) • Lies next to A site (for “Aminoacyl” site) ...
... specific site on subunit • Called P site (for “Peptidyl” site) • Lies next to A site (for “Aminoacyl” site) ...
DOCX version of Canola licence application summary
... phosphotransferase which detoxifies antibiotics such as kanamycin and neomycin, thereby conferring resistance to the bacteria in which the recombinant plasmids are maintained. This is mainly used a selectable marker for the early selection of transformed plants in tissue culture. Short regulatory se ...
... phosphotransferase which detoxifies antibiotics such as kanamycin and neomycin, thereby conferring resistance to the bacteria in which the recombinant plasmids are maintained. This is mainly used a selectable marker for the early selection of transformed plants in tissue culture. Short regulatory se ...
meiosis II
... Three events are unique to meiosis, and all three occur in meiosis l – Synapsis and crossing over in prophase I: Homologous chromosomes physically connect and exchange genetic information – At the metaphase plate, there are paired homologous chromosomes (tetrads), instead of individual replicated ch ...
... Three events are unique to meiosis, and all three occur in meiosis l – Synapsis and crossing over in prophase I: Homologous chromosomes physically connect and exchange genetic information – At the metaphase plate, there are paired homologous chromosomes (tetrads), instead of individual replicated ch ...
Visualizations of Microarray Data in Partek Genomics Suite 6.6
... PGS’s function Sort rows by prototype enables you to identify genes with similar expression profiles. For instance, if a gene with an interesting expression pattern has been detected, using Sort by prototype makes it possible to find other genes that have a similar pattern of intensity values. Altho ...
... PGS’s function Sort rows by prototype enables you to identify genes with similar expression profiles. For instance, if a gene with an interesting expression pattern has been detected, using Sort by prototype makes it possible to find other genes that have a similar pattern of intensity values. Altho ...
Previous releases and international approvals
... phosphotransferase which detoxifies antibiotics such as kanamycin and neomycin, thereby conferring resistance to the bacteria in which the recombinant plasmids are maintained. This is mainly used a selectable marker for the early selection of transformed plants in tissue culture. Short regulatory se ...
... phosphotransferase which detoxifies antibiotics such as kanamycin and neomycin, thereby conferring resistance to the bacteria in which the recombinant plasmids are maintained. This is mainly used a selectable marker for the early selection of transformed plants in tissue culture. Short regulatory se ...
MSc Seminar: Donald Dunbar
... Non specific binding of labelled target Need to exclude this background Several methods exist ...
... Non specific binding of labelled target Need to exclude this background Several methods exist ...
The presence of two UvrB subunits in the UvrAB complex ensures
... signi®cant average volume. Since these unwrapped complexes are expected to have lost the ATP molecule, we decided to analyse these complexes further by determining the volumes of UvrB±DNA complexes that were isolated by washing in the absence of ATP. As expected, no wrapped complexes were observed a ...
... signi®cant average volume. Since these unwrapped complexes are expected to have lost the ATP molecule, we decided to analyse these complexes further by determining the volumes of UvrB±DNA complexes that were isolated by washing in the absence of ATP. As expected, no wrapped complexes were observed a ...
Adaptation and Inclusive Fitness
... us to conceptualise individuals as trying to maximise something, with that ‘something’ being inclusive fitness. It is for this reason that inclusive fitness theory has played the central role in the study of adaptation, in fields such as behavioural and evolutionary ecology [3,4]. More generally, by ...
... us to conceptualise individuals as trying to maximise something, with that ‘something’ being inclusive fitness. It is for this reason that inclusive fitness theory has played the central role in the study of adaptation, in fields such as behavioural and evolutionary ecology [3,4]. More generally, by ...
Expression of Allene Oxide Synthase Determines - Bio
... concurrence with the presence of internal restriction sites for these enzymes within the cDNA sequence. The expression of the gene was highest in flowers, with low amounts of transcript being present in stem and root (Fig. 2b). In leaves and fruits, AOS mRNA was not detectable under non-inducing con ...
... concurrence with the presence of internal restriction sites for these enzymes within the cDNA sequence. The expression of the gene was highest in flowers, with low amounts of transcript being present in stem and root (Fig. 2b). In leaves and fruits, AOS mRNA was not detectable under non-inducing con ...
6.3 Mendel and Heredity
... • Mendel observed patterns in the first and second generations of his crosses. ...
... • Mendel observed patterns in the first and second generations of his crosses. ...
Site-specific recombinase technology

Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse