- Wiley Online Library
... tolerance, was identified after fine-mapping. CAX1 encodes a vacuolar Ca++/H+ exchanger that was proposed to limit Cd-induced reactive oxygen species (ROS) accumulation under low-Ca conditions (Baliardini et al., 2015). To date, only the contribution of AhHMA4 has been validated by RNA interference ...
... tolerance, was identified after fine-mapping. CAX1 encodes a vacuolar Ca++/H+ exchanger that was proposed to limit Cd-induced reactive oxygen species (ROS) accumulation under low-Ca conditions (Baliardini et al., 2015). To date, only the contribution of AhHMA4 has been validated by RNA interference ...
population genetics - E-Learning/An
... forms) refers to the observation that many traits display variation within a population. Historically, polymorphism first referred to the variation in traits that are observable with the naked eye. Polymorphisms in color and pattern have long attracted the attention of population geneticists. These ...
... forms) refers to the observation that many traits display variation within a population. Historically, polymorphism first referred to the variation in traits that are observable with the naked eye. Polymorphisms in color and pattern have long attracted the attention of population geneticists. These ...
Genetic Research and Testing in Sport and Exercise Science
... stimulated research aimed at identifying the reasons for this success. This research was first based on classical exercise physiology methods (Hamilton & Weston, 2000; Larsen, 2003) and has now been extended to molecular genetic methods (Pitsiladis & Scott, 2005), with an International Centre for Ea ...
... stimulated research aimed at identifying the reasons for this success. This research was first based on classical exercise physiology methods (Hamilton & Weston, 2000; Larsen, 2003) and has now been extended to molecular genetic methods (Pitsiladis & Scott, 2005), with an International Centre for Ea ...
Title: FISH analysis comparing the gene composition of the Onager
... Department of Biology, Crestview Hills, KY 41017, University of Kentucky2, M.H. Gluck Equine Research Center, Department of Veterinary Science, Lexington, KY 40546-0099, Conservation and Research for Endangered Species3, Zoological Society of San Diego, San Diego, CA 92027 The onager [E. hemionus on ...
... Department of Biology, Crestview Hills, KY 41017, University of Kentucky2, M.H. Gluck Equine Research Center, Department of Veterinary Science, Lexington, KY 40546-0099, Conservation and Research for Endangered Species3, Zoological Society of San Diego, San Diego, CA 92027 The onager [E. hemionus on ...
A TaqI polymorphism in the 3 UTR of the IL-12
... The fact that the TaqI polymorphism in the p40 gene has an effect on IL-12 p70 secretion, but not on IL-12 p40 secretion, is of considerable interest and, at first glance, may appear counterintuitive. One possibility is that the polymorphism affects p40 homodimer formation, which, in turn, influence ...
... The fact that the TaqI polymorphism in the p40 gene has an effect on IL-12 p70 secretion, but not on IL-12 p40 secretion, is of considerable interest and, at first glance, may appear counterintuitive. One possibility is that the polymorphism affects p40 homodimer formation, which, in turn, influence ...
Online resources for genetic variation study-Part One
... segments of strong LD (Haplotype blocks), with the average length ranging from 7.3 (YRI) to 16.3 kb (CEU), and between 65-85% of human genome presented in such blocks. ...
... segments of strong LD (Haplotype blocks), with the average length ranging from 7.3 (YRI) to 16.3 kb (CEU), and between 65-85% of human genome presented in such blocks. ...
Implementing array comparative genomic hybridization in male
... pedigrees to corroborate significance of findings, and lack of functional studies. 1,500 genes may be involved in spermatogenesis. Several hundred of these are expressed exclusively in male germs cells, which indicates that they could be candidates for causing isolated infertility. ...
... pedigrees to corroborate significance of findings, and lack of functional studies. 1,500 genes may be involved in spermatogenesis. Several hundred of these are expressed exclusively in male germs cells, which indicates that they could be candidates for causing isolated infertility. ...
PowerPoint Presentation - Meiosis
... Meiosis reduces the number of chromosomes by half. Daughter cells differ from parent, and each other. Meiosis involves two divisions, Mitosis only one. Meiosis I involves: – Synapsis – homologous chromosomes pair up. Chiasmata form (crossing over of non-sister chromatids). – In Metaphase I, homologo ...
... Meiosis reduces the number of chromosomes by half. Daughter cells differ from parent, and each other. Meiosis involves two divisions, Mitosis only one. Meiosis I involves: – Synapsis – homologous chromosomes pair up. Chiasmata form (crossing over of non-sister chromatids). – In Metaphase I, homologo ...
Chromosomal Basis of Inheritance Final
... phenomenon in 1909 and had called it 'chiasmatypie'. The term chiasma is linked if not identical to chromosomal crossover. Morgan immediately saw the great importance of Janssens' cytological interpretation of chiasmata to the experimental results of his research on the heredity of Drosophila. Janss ...
... phenomenon in 1909 and had called it 'chiasmatypie'. The term chiasma is linked if not identical to chromosomal crossover. Morgan immediately saw the great importance of Janssens' cytological interpretation of chiasmata to the experimental results of his research on the heredity of Drosophila. Janss ...
Meiosis - TeacherWeb
... Meiosis reduces the number of chromosomes by half. Daughter cells differ from parent, and each other. Meiosis involves two divisions, Mitosis only one. Meiosis I involves: – Synapsis – homologous chromosomes pair up. Chiasmata form (crossing over of non-sister chromatids). – In Metaphase I, homologo ...
... Meiosis reduces the number of chromosomes by half. Daughter cells differ from parent, and each other. Meiosis involves two divisions, Mitosis only one. Meiosis I involves: – Synapsis – homologous chromosomes pair up. Chiasmata form (crossing over of non-sister chromatids). – In Metaphase I, homologo ...
(a) (b)
... Genes on the same chromosome whose alleles are so close together that they do not assort independently (such as a, b, and c) are said to be linked. ...
... Genes on the same chromosome whose alleles are so close together that they do not assort independently (such as a, b, and c) are said to be linked. ...
PowerPoint
... Genes on the same chromosome whose alleles are so close together that they do not assort independently (such as a, b, and c) are said to be linked. ...
... Genes on the same chromosome whose alleles are so close together that they do not assort independently (such as a, b, and c) are said to be linked. ...
Lecture PDF - Carol Eunmi LEE
... disappearance slows down As homozygote recessive allele becomes rare, most are in the heterozygous state and are masked from selection ...
... disappearance slows down As homozygote recessive allele becomes rare, most are in the heterozygous state and are masked from selection ...
Genomic organisation of the Mal d 1 gene cluster on linkage group
... complex allergen gene family. Not all Mal d 1 members are likely to be involved in allergenicity. Therefore, additional knowledge about the existence and characteristics of the different Mal d 1 genes is required. In the present study, we investigated the genomic organisation of the Mal d 1 gene clu ...
... complex allergen gene family. Not all Mal d 1 members are likely to be involved in allergenicity. Therefore, additional knowledge about the existence and characteristics of the different Mal d 1 genes is required. In the present study, we investigated the genomic organisation of the Mal d 1 gene clu ...
PROCUSTE1 Encodes a Cellulose Synthase Required for Normal
... culture conditions used, neither wild-type nor prc1-1 accumulated significant levels of (1→3)--glucan (callose). Also, staining with iodine failed to detect starch in wild-type or prc1-1 hypocotyls (data not shown). The presence of minor amounts of xylosyl (5%), rhamnosyl (6%), uronic acid (10%), g ...
... culture conditions used, neither wild-type nor prc1-1 accumulated significant levels of (1→3)--glucan (callose). Also, staining with iodine failed to detect starch in wild-type or prc1-1 hypocotyls (data not shown). The presence of minor amounts of xylosyl (5%), rhamnosyl (6%), uronic acid (10%), g ...
Lecture PPT - Carol Eunmi LEE
... If the virus is likely to move to a new host, the faster growing (and more virulent) strain is likely to overtake the slower strains and “win” ...
... If the virus is likely to move to a new host, the faster growing (and more virulent) strain is likely to overtake the slower strains and “win” ...
NIH Public Access
... below, it is essential that its binding be strictly cis limited. We interpret this to likely require multiple redundant anchor points and cooperative players to assure strict and stable XIST RNA binding. Both human XIST and mouse Xist RNAs contain multiple regions of tandem repeats (identified as re ...
... below, it is essential that its binding be strictly cis limited. We interpret this to likely require multiple redundant anchor points and cooperative players to assure strict and stable XIST RNA binding. Both human XIST and mouse Xist RNAs contain multiple regions of tandem repeats (identified as re ...
Translational Repression of C. elegans p53 by GLD
... tumors have defects in upstream signaling components of the p53 pathway such as inactivation of the positive regulators ARF or CHK2 (Sharpless and DePinho, 1999; Bartek and Lukas, 2003), or overexpression of the negative regulator Mdm2 (Freedman et al., 1999). For those tumors that retain functional ...
... tumors have defects in upstream signaling components of the p53 pathway such as inactivation of the positive regulators ARF or CHK2 (Sharpless and DePinho, 1999; Bartek and Lukas, 2003), or overexpression of the negative regulator Mdm2 (Freedman et al., 1999). For those tumors that retain functional ...
Lessons from Phenylketonuria. Trends Genet 15:267
... PAH; thus, locus heterogeneity for HPA was identified. In the 1980s the human PAH gene (cDNA sequence, GenBank U49897) was mapped to human chromosome 12q24.1, cloned and some mutations identified. By 1999, over 400 mutant alleles have been detected, largely by members of the PAH Mutation Analysis Co ...
... PAH; thus, locus heterogeneity for HPA was identified. In the 1980s the human PAH gene (cDNA sequence, GenBank U49897) was mapped to human chromosome 12q24.1, cloned and some mutations identified. By 1999, over 400 mutant alleles have been detected, largely by members of the PAH Mutation Analysis Co ...
What is known about interactions between genes and the
... members being similar to each other, whereas ‘non-shared’ environmental effects refer to those that result in family members being different to one another (and this latter component also includes measurement error). Thus, it is the effect of the environment, rather than the environment event per se ...
... members being similar to each other, whereas ‘non-shared’ environmental effects refer to those that result in family members being different to one another (and this latter component also includes measurement error). Thus, it is the effect of the environment, rather than the environment event per se ...
Using Dimensional Models of Externalizing Psychopathology to Aid
... laboratories at Indiana University and Washington University in St Louis using radioactive- and fluorescence-based detection systems, as described previously.46 The current analyses are based on a map of 315 autosomal microsatellite markers with a mean intermarker distance of 11.5 cM. Pedigrees were ...
... laboratories at Indiana University and Washington University in St Louis using radioactive- and fluorescence-based detection systems, as described previously.46 The current analyses are based on a map of 315 autosomal microsatellite markers with a mean intermarker distance of 11.5 cM. Pedigrees were ...
i. Genetics
... of all cells in all living organisms The kind of cell which is formed, (muscle, blood, nerve etc.) is controlled by DNA The kind of organism which is produced (giraffe, herring, human, etc.) is controlled by DNA ...
... of all cells in all living organisms The kind of cell which is formed, (muscle, blood, nerve etc.) is controlled by DNA The kind of organism which is produced (giraffe, herring, human, etc.) is controlled by DNA ...
Tufts` Canine and Feline Breeding and Genetics Conference
... Because of the increased awareness of breeders, pet owners, and veterinarians of genetic defects and the improved diagnostic abilities in clinical practice, the number of reported hereditary diseases in small animals is rapidly growing. While in humans around five thousand disorders have been descri ...
... Because of the increased awareness of breeders, pet owners, and veterinarians of genetic defects and the improved diagnostic abilities in clinical practice, the number of reported hereditary diseases in small animals is rapidly growing. While in humans around five thousand disorders have been descri ...
selection for recombination in small populations
... drift. In particular, we ask whether disequilibrium generated by epistasis or by drift is more likely to account for the changes in recombination that have been observed experimentally. Finally, we suggest experiments to distinguish the relative contributions of these two sources of disequilibria. M ...
... drift. In particular, we ask whether disequilibrium generated by epistasis or by drift is more likely to account for the changes in recombination that have been observed experimentally. Finally, we suggest experiments to distinguish the relative contributions of these two sources of disequilibria. M ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse