Chromosome location and characterization of genes for grain
... m-1) had the lowest yields among the LDN-DIC lines.. The three lines all had unique characteristics contributing to their low grain yield. LDN(521-3A) produced weak plants and were the shortest in plant height and they had the smallest spikes of the LDN-DIC lines. LDN(742-2B) produced weak stands, w ...
... m-1) had the lowest yields among the LDN-DIC lines.. The three lines all had unique characteristics contributing to their low grain yield. LDN(521-3A) produced weak plants and were the shortest in plant height and they had the smallest spikes of the LDN-DIC lines. LDN(742-2B) produced weak stands, w ...
DOCX format - 129 KB - Office of the Gene Technology Regulator
... In the Monitoring Zone the only plants which may be grown are GM plants authorised under another licence issued by the Regulator, or plants approved in writing by the Regulator. The Monitoring Zone must be surrounded by an Isolation Zone of 190 m extending from the outer edge of the Monitoring Zone. ...
... In the Monitoring Zone the only plants which may be grown are GM plants authorised under another licence issued by the Regulator, or plants approved in writing by the Regulator. The Monitoring Zone must be surrounded by an Isolation Zone of 190 m extending from the outer edge of the Monitoring Zone. ...
Huntingtin function during zebrafish (Danio rerio) development
... functions of these proteins have therefore become a focus of investigation as potential pathogenic pathways. Here, synthetic antisense morpholinos have been used to inhibit the translation of huntingtin protein during early zebrafish development. The results obtained show the effects of huntingtin l ...
... functions of these proteins have therefore become a focus of investigation as potential pathogenic pathways. Here, synthetic antisense morpholinos have been used to inhibit the translation of huntingtin protein during early zebrafish development. The results obtained show the effects of huntingtin l ...
PROGRAM PROGRAM
... • Novel candidates for host response to BLV infection in Holstein cattle based on genome-wide association study (P. Brym) – 12 min • Comparing gene expression profiles in the mammary glands of high- and low-milkyield Holstein Friesian cows (M. Miller) – 12 min • Association between polymorphisms ...
... • Novel candidates for host response to BLV infection in Holstein cattle based on genome-wide association study (P. Brym) – 12 min • Comparing gene expression profiles in the mammary glands of high- and low-milkyield Holstein Friesian cows (M. Miller) – 12 min • Association between polymorphisms ...
Tapanes-Castillo A, Weaver EJ, Smith RP, Kamei Y, Caspary T, Hamilton-Nelson KL, Slifer SH, Martin ER, Bixby JL, Lemmon VP. Neurogenetics. 2012 Feb;11(1):53-71. A modifier locus on chromosome 5 contributes to L1 cell adhesion molecule X-linked hydrocephalus in mice.
... on the reason for the defect in CSF flow. Communicating hydrocephalus arises from problems with CSF secretion or resorption; CSF flows freely between the ventricles and the subarachnoid space. On the other hand, noncommunicating hydrocephalus develops when a physical obstruction blocks CSF flow betw ...
... on the reason for the defect in CSF flow. Communicating hydrocephalus arises from problems with CSF secretion or resorption; CSF flows freely between the ventricles and the subarachnoid space. On the other hand, noncommunicating hydrocephalus develops when a physical obstruction blocks CSF flow betw ...
PDF reprint - Stanford Medicine
... Drosophila genomic DNA and obtained six DNA fragments that satisfied genetic criteria in yeast for Tin binding sites (Figure 1B). Most of the genomic DNA fragments were isolated multiple times. Sequence analysis confirmed the presence of core recognition sites for NK class homeodomains in all of the ...
... Drosophila genomic DNA and obtained six DNA fragments that satisfied genetic criteria in yeast for Tin binding sites (Figure 1B). Most of the genomic DNA fragments were isolated multiple times. Sequence analysis confirmed the presence of core recognition sites for NK class homeodomains in all of the ...
Investigating the functional significance of evolutionarily conserved
... Bilaterans share a common anterior-posterior (A-P) axis that is patterned by the Homeotic selector (Hox) genes. In Drosophila melanogaster, Hox gene expression in spatially restricted domains along the A-P axis of the embryo determines segmental identity. Identifying the genetic mechanisms of HOX co ...
... Bilaterans share a common anterior-posterior (A-P) axis that is patterned by the Homeotic selector (Hox) genes. In Drosophila melanogaster, Hox gene expression in spatially restricted domains along the A-P axis of the embryo determines segmental identity. Identifying the genetic mechanisms of HOX co ...
A caudal mRNA gradient controls posterior development in the wasp
... anteroposterior patterning in insects that lack Bicoid can provide insight into the evolution of the diversity of body plan patterning networks. To this end, we have established the long germ parasitic wasp Nasonia vitripennis as a model for comparative studies with Drosophila. Here we report that, ...
... anteroposterior patterning in insects that lack Bicoid can provide insight into the evolution of the diversity of body plan patterning networks. To this end, we have established the long germ parasitic wasp Nasonia vitripennis as a model for comparative studies with Drosophila. Here we report that, ...
Rapid Microscope Based Identification Method for Tuberculosis and
... may be caused by several parameters, such as low rRNA content due to low metabolism, or weak permeabiliziation of the cell so that the probe cannot penetrate into the cell. To increase the permeability in general, different types of chemical-physical treatments or enzymes (e.g. lysozyme, mutanolysin ...
... may be caused by several parameters, such as low rRNA content due to low metabolism, or weak permeabiliziation of the cell so that the probe cannot penetrate into the cell. To increase the permeability in general, different types of chemical-physical treatments or enzymes (e.g. lysozyme, mutanolysin ...
BIO 402 - National Open University of Nigeria
... characteristics. Weismann speculated that the chromosomes of the sex cells were the carriers of his germsplasm, but he erred in assuming that each chromosome could contain all hereditary material. He also postulated that a periodic reduction in chromosome number must occur in all sexual organisms a ...
... characteristics. Weismann speculated that the chromosomes of the sex cells were the carriers of his germsplasm, but he erred in assuming that each chromosome could contain all hereditary material. He also postulated that a periodic reduction in chromosome number must occur in all sexual organisms a ...
Alternatively Spliced Genes
... RNA precursor, or pre-mRNA) (as depicted in •Fig. 1). The discovery of split genes in the viral genome and subsequent research in the field of pre-mRNA splicing have greatly advanced our understanding of mammalian gene regulation. Studies on pre-mRNA splicing have also facilitated sequence analyses o ...
... RNA precursor, or pre-mRNA) (as depicted in •Fig. 1). The discovery of split genes in the viral genome and subsequent research in the field of pre-mRNA splicing have greatly advanced our understanding of mammalian gene regulation. Studies on pre-mRNA splicing have also facilitated sequence analyses o ...
Document
... Lesson 3 - Relate genotype and phenotype to nucleotide sequences in DNA. Lesson 4 - Sequence the steps in protein synthesis. Lesson 5 - Categorize different kinds of mutation in DNA. Lesson 6 - Compare the effects of different kinds of mutations on cells and organisms. Unit 9 - Principles of Evoluti ...
... Lesson 3 - Relate genotype and phenotype to nucleotide sequences in DNA. Lesson 4 - Sequence the steps in protein synthesis. Lesson 5 - Categorize different kinds of mutation in DNA. Lesson 6 - Compare the effects of different kinds of mutations on cells and organisms. Unit 9 - Principles of Evoluti ...
The KetelD Dominant-Negative Mutations Identify
... times but instead of separation they organize rudimentary asters of MTs along with a general decay of the egg cytoplasm. (Behavior of the polar body nuclei was not different in wild-type and in Ketel D eggs and served as a reference for timing the initial events of embryogenesis.) The Ketel D mutant ...
... times but instead of separation they organize rudimentary asters of MTs along with a general decay of the egg cytoplasm. (Behavior of the polar body nuclei was not different in wild-type and in Ketel D eggs and served as a reference for timing the initial events of embryogenesis.) The Ketel D mutant ...
Effete, a Drosophila chromatin-associated ubiquitin
... respectively (Fanti et al. 1998; Cenci et al. 2003); without children (woc) that specifies a putative transcription factor (Raffa et al. 2005); modigliani (moi) that encodes a nonconserved HOAP-binding protein (Raffa et al. 2009); and verrocchio (ver) that specifies an OB-fold containing protein str ...
... respectively (Fanti et al. 1998; Cenci et al. 2003); without children (woc) that specifies a putative transcription factor (Raffa et al. 2005); modigliani (moi) that encodes a nonconserved HOAP-binding protein (Raffa et al. 2009); and verrocchio (ver) that specifies an OB-fold containing protein str ...
How to Model Microevolution How to Model Microevolution
... include at the minimum the passing of genetic material from one generation to the next. Hence, our fundamental time unit will be the transition between two consecutive generations at comparable stages. All such trans-generational models of microevolution have to make assumptions about three major me ...
... include at the minimum the passing of genetic material from one generation to the next. Hence, our fundamental time unit will be the transition between two consecutive generations at comparable stages. All such trans-generational models of microevolution have to make assumptions about three major me ...
Chromosome Variation
... reduced (see Figure 9.7d). Bar arises from unequal crossing over, a duplication-generating process ( ◗ FIGURE 9.8; see also Figure 17.17). How does a chromosome duplication alter the phenotype? After all, gene sequences are not altered by duplications, and no genetic information is missing; the only ...
... reduced (see Figure 9.7d). Bar arises from unequal crossing over, a duplication-generating process ( ◗ FIGURE 9.8; see also Figure 17.17). How does a chromosome duplication alter the phenotype? After all, gene sequences are not altered by duplications, and no genetic information is missing; the only ...
neurotic, a novel maternal neurogenic gene, encodes an O
... knock down nti function in cultured cells (see below). These results demonstrate that CG12366 encodes nti function. Database searches revealed that nti encodes a putative protein with significant homology to human GDP-fucose Ofucosyltransferase 1 (Wang et al., 2001) (O-FucT-1; Fig. 2A). O-FucT-1 is ...
... knock down nti function in cultured cells (see below). These results demonstrate that CG12366 encodes nti function. Database searches revealed that nti encodes a putative protein with significant homology to human GDP-fucose Ofucosyltransferase 1 (Wang et al., 2001) (O-FucT-1; Fig. 2A). O-FucT-1 is ...
Literature Study
... performed. Among the first of these studies was the study of Butler et al., in which they undertook PTEN mutation analysis in 18 subjects with ASD and macrocephaly(Butler and others 2005). The three subjects with the largest head circumference turned out to have mutation is the PTEN gene, which indi ...
... performed. Among the first of these studies was the study of Butler et al., in which they undertook PTEN mutation analysis in 18 subjects with ASD and macrocephaly(Butler and others 2005). The three subjects with the largest head circumference turned out to have mutation is the PTEN gene, which indi ...
The Influence of Anticodon–Codon Interactions and Modified Bases
... occurs in some mitochondria. Therefore, our figure 1c includes all these cases. This means that more than one tRNA can translate most codons, and the total rate of translation of each codon is dependent on the sum of the rates at which all tRNA types translate the codon. This is an important part of ...
... occurs in some mitochondria. Therefore, our figure 1c includes all these cases. This means that more than one tRNA can translate most codons, and the total rate of translation of each codon is dependent on the sum of the rates at which all tRNA types translate the codon. This is an important part of ...
The landscape of Neandertal ancestry in present
... To explore whether selection provides part of the explanation for regions of reduced Neandertal ancestry, we tested for a correlation of Neandertal ancestry to a previously defined “B-statistic”, in which low B implies a high density of functionally important elements18. We find that low B is signif ...
... To explore whether selection provides part of the explanation for regions of reduced Neandertal ancestry, we tested for a correlation of Neandertal ancestry to a previously defined “B-statistic”, in which low B implies a high density of functionally important elements18. We find that low B is signif ...
Changes in retinoic acid signaling alter otic patterning
... Otic defects generated by changes in RA signaling are considered mostly secondary consequences due to changes in Fgf signaling, because hindbrain patterning is disturbed in RA gain- and loss-offunction studies. In embryos with no RA signaling, such as mouse Aldh1a2 mutants, expression of Fgf3, which ...
... Otic defects generated by changes in RA signaling are considered mostly secondary consequences due to changes in Fgf signaling, because hindbrain patterning is disturbed in RA gain- and loss-offunction studies. In embryos with no RA signaling, such as mouse Aldh1a2 mutants, expression of Fgf3, which ...
Visceral endoderm-restricted translation of Otx1
... functional properties might largely overlap and differences in their temporal and spatial transcriptional control might account for the highly divergent phenotypes observed in mice lacking Otx1 or Otx2, or (ii) Otx1 and Otx2 gene products might display unique functional properties, specified by thei ...
... functional properties might largely overlap and differences in their temporal and spatial transcriptional control might account for the highly divergent phenotypes observed in mice lacking Otx1 or Otx2, or (ii) Otx1 and Otx2 gene products might display unique functional properties, specified by thei ...
Figures 1
... an imprinting defect (1–3%). Parent-specific DNA methylation analysis will detect >99% of individuals. However, additional genetic studies are necessary to identify the molecular class. There are multiple imprinted genes in this region, the loss of which contribute to the complete phenotype of Prade ...
... an imprinting defect (1–3%). Parent-specific DNA methylation analysis will detect >99% of individuals. However, additional genetic studies are necessary to identify the molecular class. There are multiple imprinted genes in this region, the loss of which contribute to the complete phenotype of Prade ...
Product description P018-G1 SHOX-v03 - MRC
... To be used in combination with a SALSA® MLPA® reagent kit, available for various number of reactions. MLPA reagent kits are either provided with FAM or Cy5.0 dye-labelled PCR primer, suitable for Applied Biosystems and Beckman capillary sequencers, respectively (see www.mlpa.com). Certificate of Ana ...
... To be used in combination with a SALSA® MLPA® reagent kit, available for various number of reactions. MLPA reagent kits are either provided with FAM or Cy5.0 dye-labelled PCR primer, suitable for Applied Biosystems and Beckman capillary sequencers, respectively (see www.mlpa.com). Certificate of Ana ...
adenomi ipofisari familiari
... the proliferation stage Cellular PKA responses to cAMP can differ significantly depending on the PKA type and tissue-specific expression of phosphorylated molecular targets Bossis I et al 2004 Endocrine-Related Cancer 11:265–280 ...
... the proliferation stage Cellular PKA responses to cAMP can differ significantly depending on the PKA type and tissue-specific expression of phosphorylated molecular targets Bossis I et al 2004 Endocrine-Related Cancer 11:265–280 ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse