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Steve Masson
Steve Masson

... sequence information, and to predict protein sequence and structure from DNA sequence data. ...
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03-Heredity &Environment

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No Slide Title

... One goal of Functional Genomics is to define the function of all genes, and to define how genes interact to form more complicated networks responsible for biological processes. Ways we have discussed to accomplish this: ...
Environment and Gene Expression Scientists have learned that
Environment and Gene Expression Scientists have learned that

... now clear that not all genes are expressed in every cell, nor are many genes expressed all of the time. Cells have complex systems that regulate whether or not specific genes are expressed. Expression depends on the cell’s need and environment. Through gene regulation, a given sequence can be expres ...
Principles of genetic engineering
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... affect how genes of fur color or height are expressed. Linkage – genes (traits) that are close together on one chromosome are less likely to separate during meiosis and are said to be linked. ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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