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Evolution: Library: Genetic Drift and the Founder Effect
Evolution: Library: Genetic Drift and the Founder Effect

... Eastern Pennsylvania is home to beautiful farmlands and countryside, but it's also a gold mine of information for geneticists, who have studied the region's Amish culture for decades. Because of their closed population stemming from a small number of German immigrants -- about 200 individuals -- the ...
Visualizing gene expression and function at the cellular level
Visualizing gene expression and function at the cellular level

... • Genotyping is the procedure used to determine differences in the genetic make-up (genotype) of an individual by examining the individual's DNA sequence using biological assays and comparing it to another individual's sequence or a reference sequence. • In our experiment we wanted to know the diffe ...
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... A: For yeast, a minimum of 20 genes is required to recover 95% bootstrap values for each branch of the species tree (Rokas et al. 2003, Nature) ...
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... the 2 September issue of Nature Medicine. Ciliopathies include diseases as diverse as polycystic kidney disease and retinitis pigmentosa, an inherited, degenerative eye disease that causes severe vision impairment and blindness. In the olfactory system, multiple cilia project from olfactory sensory ...
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Chapter 26: Biotechnology
Chapter 26: Biotechnology

... three billion base pairs after 15 years of research. The two agencies that completed the task are The International Human Genome Sequencing Consortium and Celera Genomics, a private company. ...
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It`s All in the Genes
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bio ch14.3 ppt - Mrs. Graves Science

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Chapter 5 PRINCIPLES OF INHERITANCE AND VARIATION One

... is the observation made by him in that experiment? Morgan hybridized yellow bodied, white eyed females to brown-bodied, red eyed male and intercrossed their F1 progeny. He observed that the two genes did not segregate independently of each other and the F2 ratio deviated very significantly from 9:3: ...
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... - people have genetically different sensitivities to different toxins. Certain genes are associated with higher rates of certain types of cancer, for example. However, they are not ‘deterministic’… their effects must be activated by some environmental variable. PKU = phenylketonuria… genetic inabili ...
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Exploring gene promoters for experimentally

... c-Fos, STAT3, Smad3, ER and more. Continuing on to the Locus Report for human VEGFA in TRANSFAC® Professional and the corresponding Gene Report/Entry for VEGF (VEGFA) in TRANSFAC® Public in search of more detailed information about the exact nature of the described factor-DNA interactions, we find t ...
Power Point 2 - G. Holmes Braddock
Power Point 2 - G. Holmes Braddock

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Introduction to Genetics Terms

... 16. Independent Assortment: This is when genes for different traits are not necessarily inherited together. For example, yellow peas can be on either short or tall plants. 17. Incomplete Dominance: This is when one allele is not completely dominant over the other allele. For example, red and white f ...
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Gene Transcription in Prokaryotes

... participating in a common pathway are organized together. – This group of genes, arranged in tandem, is called an OPERON. ...
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ONE GENE, TWO DISEASES: SCN5A AND ITS ROLE IN LONG QT

... Long QT (LQTS) and Brugada syndrome cause deaths in young individuals with structurally normal hearts. Cardiac arrhythmias include the long-QT syndrome (LQTS), the Brugada syndrome (BrS), the short-QT syndrome (SQTS) and the catecholaminergic polymorphic ventricular tachycardia (CPVT). Mutations in ...
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Kostas Konstantinidis - Metagenomics Resources!

... - What is the progress on integrating different sequencing platforms? - How big a computer do I really need to do everything I want? Is it reasonable to expect access to this for myself? - Is metagenomics really useful and worth the investment? - What are the most useful tools you use regularly? - H ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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