Ch. 7: Presentation Slides
... chromosome 21 is one of the acrocentrics in a Robertsonian translocation, the rearrangement leads to a familial type of Down syndrome • The heterozygous carrier is phenotypically normal, but a high risk of Down syndrome results from aberrant segregation in meiosis • Approximately 3 percent of childr ...
... chromosome 21 is one of the acrocentrics in a Robertsonian translocation, the rearrangement leads to a familial type of Down syndrome • The heterozygous carrier is phenotypically normal, but a high risk of Down syndrome results from aberrant segregation in meiosis • Approximately 3 percent of childr ...
Unexpected requirements for neural induction in the
... Alternatively, FGF might act indirectly through induced mesoderm, and the available experimental data need further analysis (e.g. in order to eliminate a discrepancy with respect to the brachyury marker). The fast activation of brachyury by factors such as FGF2, FGF4, FGF8b and FGF9 suggests that th ...
... Alternatively, FGF might act indirectly through induced mesoderm, and the available experimental data need further analysis (e.g. in order to eliminate a discrepancy with respect to the brachyury marker). The fast activation of brachyury by factors such as FGF2, FGF4, FGF8b and FGF9 suggests that th ...
Regulation of Ovule Development
... locules are separated by a central septum. During gynoecium development, longitudinal medial ridges, several cells wide, protrude from opposite sides into the center of the cylinder formed by the elongation of the fused carpel primordia (Figure 2A) (Bowman et al., 1999). The ridges of cells fuse and ...
... locules are separated by a central septum. During gynoecium development, longitudinal medial ridges, several cells wide, protrude from opposite sides into the center of the cylinder formed by the elongation of the fused carpel primordia (Figure 2A) (Bowman et al., 1999). The ridges of cells fuse and ...
Solving the shugoshin puzzle
... Divergent gene orientation is highly conserved We calculated the fraction of adjacent gene pairs that are conserved in orientation between every possible pair of species and plotted it against the species’ divergence times (Figure 1a; see Supplementary Material 1). At large evolutionary distances of ...
... Divergent gene orientation is highly conserved We calculated the fraction of adjacent gene pairs that are conserved in orientation between every possible pair of species and plotted it against the species’ divergence times (Figure 1a; see Supplementary Material 1). At large evolutionary distances of ...
Future Dog Breeding for Genetic Soundness
... aggregates deleterious genes, producing disorders that may not be apparent in every generation. These disorders often go undetected until the condition becomes frequent enough to be recognized as inherited.Generations may be unaffected when carriers are rare. As unaffected carriers become common, mo ...
... aggregates deleterious genes, producing disorders that may not be apparent in every generation. These disorders often go undetected until the condition becomes frequent enough to be recognized as inherited.Generations may be unaffected when carriers are rare. As unaffected carriers become common, mo ...
the molecular similarity between Mowat-Wilson syndrome
... Zeb2-cKO mice. To examine the changes in gene expression in dermal fibroblasts derived from Zeb2-cKO ...
... Zeb2-cKO mice. To examine the changes in gene expression in dermal fibroblasts derived from Zeb2-cKO ...
Gene Section LMO2 (LIM domain only 2 (rhombotin-like 1))
... Hematopoiesis: LMO2 directly interacts with the basicloop-helix protein TAL1/SCL and the GATA DNA protein GATA1. They form a transcriptional complex: LMO2 has no direct evidence in DNA binding capacity but could act as a bridging molecule bringing together different DNA binding factors (TAL1, LDB1, ...
... Hematopoiesis: LMO2 directly interacts with the basicloop-helix protein TAL1/SCL and the GATA DNA protein GATA1. They form a transcriptional complex: LMO2 has no direct evidence in DNA binding capacity but could act as a bridging molecule bringing together different DNA binding factors (TAL1, LDB1, ...
Cross talk between signaling pathways in pathogen defense
... that do not accumulate high levels of SA [46••,47••]. Thus, constitutive SA signaling in the mpk4 and ssi2 mutants is likely due to loss of an antagonistic effect of JA signaling on the SA pathway. MPK4 is predicted to encode a mitogenactivated (MAP) kinase that is required for JA-dependent gene exp ...
... that do not accumulate high levels of SA [46••,47••]. Thus, constitutive SA signaling in the mpk4 and ssi2 mutants is likely due to loss of an antagonistic effect of JA signaling on the SA pathway. MPK4 is predicted to encode a mitogenactivated (MAP) kinase that is required for JA-dependent gene exp ...
Biology Mendel and Heredity
... _______________________ alleles are indicated by writing the _____________ letter of the trait as a _____________________ letter. __________________________ alleles are also indicated by writing the first letter of the _______________________ trait, but the letter is _____________________________. I ...
... _______________________ alleles are indicated by writing the _____________ letter of the trait as a _____________________ letter. __________________________ alleles are also indicated by writing the first letter of the _______________________ trait, but the letter is _____________________________. I ...
Gene density and transcription influence the localization of
... localization outside of chromosome territories is not a common feature of imprinted regions. Localization outside of a chromosome territory is common to gene-rich regions of the human genome The relative intraterritory position of loci from 15q12 was intermediate to that of 11p13 (Mahy et al., 2002) ...
... localization outside of chromosome territories is not a common feature of imprinted regions. Localization outside of a chromosome territory is common to gene-rich regions of the human genome The relative intraterritory position of loci from 15q12 was intermediate to that of 11p13 (Mahy et al., 2002) ...
wsp Gene Sequences from the Wolbachia of Filarial Nematodes
... major outer membrane proteins of Anaplasma, Ehrlichia, and Cowdria species. While alignment among wsp sequences was unambiguous along most of the gene, alignment with the surface-protein genes of Anaplasma, Ehrlichia, and Cowdria appeared unreliable (not shown). As expected from the unreliability of ...
... major outer membrane proteins of Anaplasma, Ehrlichia, and Cowdria species. While alignment among wsp sequences was unambiguous along most of the gene, alignment with the surface-protein genes of Anaplasma, Ehrlichia, and Cowdria appeared unreliable (not shown). As expected from the unreliability of ...
A DEAD Box RNA Helicase Is Essential for mRNA Export and
... transcription, pre-mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay, and organellar gene expression (de la Cruz et al., 1999; Tanner and Linder, 2001; Lorsch, 2002). The DEAD box RNA helicases compose the largest subfamily of RNA helicases. BLAST searches with ...
... transcription, pre-mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay, and organellar gene expression (de la Cruz et al., 1999; Tanner and Linder, 2001; Lorsch, 2002). The DEAD box RNA helicases compose the largest subfamily of RNA helicases. BLAST searches with ...
org.Mm.eg.db
... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
In Vitro Cell. Dev. Biol. In Press
... Plant transformation and regeneration. Co-cultivated explants regenerated shoots after transfer to regeneration medium. On 2 mg l21 PPT or kanamycin (100 mg l21) and 300 mg l21 cefotaxime small shoots began to develop. In PPT-containing medium, shoots died after 10 d of culture due to their sensitiv ...
... Plant transformation and regeneration. Co-cultivated explants regenerated shoots after transfer to regeneration medium. On 2 mg l21 PPT or kanamycin (100 mg l21) and 300 mg l21 cefotaxime small shoots began to develop. In PPT-containing medium, shoots died after 10 d of culture due to their sensitiv ...
Exclusion of known corneal dystrophy genes in an autosomal
... Purpose: With advances in phenotyping tools and availability of molecular characterization, an increasing number of phenotypically and genotypically diverse inherited corneal dystrophies are described. We aimed to determine the underlying causative genetic mechanism in a three-generation pedigree af ...
... Purpose: With advances in phenotyping tools and availability of molecular characterization, an increasing number of phenotypically and genotypically diverse inherited corneal dystrophies are described. We aimed to determine the underlying causative genetic mechanism in a three-generation pedigree af ...
Structure, expression and chromosomal location of the Oct
... the relevant parental t-haplotypes. This lack of polymorphism was not unexpected because all t-haplotypes are generally believed to be descended from a single ancestral chromosome. Another approach to examine the relationship between Oct-4 and t 12 is to analyze the genomic structure and sequence of ...
... the relevant parental t-haplotypes. This lack of polymorphism was not unexpected because all t-haplotypes are generally believed to be descended from a single ancestral chromosome. Another approach to examine the relationship between Oct-4 and t 12 is to analyze the genomic structure and sequence of ...
Origin and Distribution of Calvin Cycle Fructose and
... another "red" gene in Bigelowiella has previously been reported for plastid phosphoribulokinase (PRK; Petersen et al. 2006). Furthermore, an ancient gene duplication in rhodophytes led to an additional SBP copy only found in the Cyanidiales (Cyanidioschyzon [B] plus Galdieria [B]). From within the r ...
... another "red" gene in Bigelowiella has previously been reported for plastid phosphoribulokinase (PRK; Petersen et al. 2006). Furthermore, an ancient gene duplication in rhodophytes led to an additional SBP copy only found in the Cyanidiales (Cyanidioschyzon [B] plus Galdieria [B]). From within the r ...
It`s In Your Genes
... have a total length of about 1.7 meters! Human DNA, however, is tightly coiled so that it fits inside the cell’s nucleus (its computer). In humans, DNA is separated into 46 linear strands called chromosomes. Genes are chemical codes that determine specific traits such as the shape of your chin, the ...
... have a total length of about 1.7 meters! Human DNA, however, is tightly coiled so that it fits inside the cell’s nucleus (its computer). In humans, DNA is separated into 46 linear strands called chromosomes. Genes are chemical codes that determine specific traits such as the shape of your chin, the ...
... situation is one of skepticism, when any one asserts either that such quantitative paired genes are generally dominant and recessive, respectively, or that they generally have an intermediate effect in the heterozygous phase as compared with the two alternative homozygous phases. I n view of the com ...
Ectopic overexpression of castor bean LEAFY
... and the seed-specific OLEOSIN isoforms identified in oil bodies from mature Arabidopsis seeds [15]. LEC2 binds directly to the promoter of HDS1 [14] and the RY element found in the promoters of OLEOSIN genes [15,16]. Baud et al. [17] demonstrated that the WRINKLED1 (WRI1) TF [18] is an essential targe ...
... and the seed-specific OLEOSIN isoforms identified in oil bodies from mature Arabidopsis seeds [15]. LEC2 binds directly to the promoter of HDS1 [14] and the RY element found in the promoters of OLEOSIN genes [15,16]. Baud et al. [17] demonstrated that the WRINKLED1 (WRI1) TF [18] is an essential targe ...
Ira Herskowitz: 1946-2003.
... The sixth chapter of Ira’s thesis describes an entirely different line of investigation, one that was to have comparable influence on molecular genetics in the future. This was a collaboration with Costa Georgopoulos, who had recently obtained his Ph.D. at MIT for thesis work done on the glycosylati ...
... The sixth chapter of Ira’s thesis describes an entirely different line of investigation, one that was to have comparable influence on molecular genetics in the future. This was a collaboration with Costa Georgopoulos, who had recently obtained his Ph.D. at MIT for thesis work done on the glycosylati ...
DCM in Dobermann is a disease with variable Prevalence and
... Risk perception is subjective and everyone can see the glass half full or half empty as it seems. It is discussed in this section about Fedor. Can be him an affected DD or Dd? Probably no, because he has almost surpassed the age at risk (8 years). Can be him a silent carrier DD* or Dd*? Maybe yes, ...
... Risk perception is subjective and everyone can see the glass half full or half empty as it seems. It is discussed in this section about Fedor. Can be him an affected DD or Dd? Probably no, because he has almost surpassed the age at risk (8 years). Can be him a silent carrier DD* or Dd*? Maybe yes, ...
channel 1 gene dosage
... Hybridization signals of ClC-1 mRNA were normalized using either the 18S rRNA or the GAPDH mRNA, or both signals obtained by a subsequent hybridization of the same filter. In more recent experiments, 32P-hybridization signals (after localizing the radioactivity by autoradiography) were quantified wi ...
... Hybridization signals of ClC-1 mRNA were normalized using either the 18S rRNA or the GAPDH mRNA, or both signals obtained by a subsequent hybridization of the same filter. In more recent experiments, 32P-hybridization signals (after localizing the radioactivity by autoradiography) were quantified wi ...
Understanding Reproductive Isolation Based on the Rice
... 43, 53, 57, 60, 77, 98, 105). Molecular characterization of these genes, also referred to as speciation genes, has begun to shed light on the biological mechanisms controlling the processes of reproductive isolation. In plants, the best-characterized example of postzygotic reproductive isolation is ...
... 43, 53, 57, 60, 77, 98, 105). Molecular characterization of these genes, also referred to as speciation genes, has begun to shed light on the biological mechanisms controlling the processes of reproductive isolation. In plants, the best-characterized example of postzygotic reproductive isolation is ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.