Duplication 12p and PallisterKillian syndrome
... FGFR2 as well as the GLI3 gene, all of which were within normal limits. BAC array comparative genomic hybridization was performed, and revealed a 12p13.31 microduplication and a 16p13.11 microdeletion. To further refine the breakpoint of microduplication, single nucleotide polymorphism (SNP) microarr ...
... FGFR2 as well as the GLI3 gene, all of which were within normal limits. BAC array comparative genomic hybridization was performed, and revealed a 12p13.31 microduplication and a 16p13.11 microdeletion. To further refine the breakpoint of microduplication, single nucleotide polymorphism (SNP) microarr ...
hermann joseph muller 1890—1967
... Sturtevant used the data from Morgan’s first X-linked mutations and constructed a map. Muller was in awe of Sturtevant’s interpretation. (Sturtevant was still an undergraduate when he created the first map). Muller suggested using the ratio of crossovers to the total of crossovers and noncrossovers ...
... Sturtevant used the data from Morgan’s first X-linked mutations and constructed a map. Muller was in awe of Sturtevant’s interpretation. (Sturtevant was still an undergraduate when he created the first map). Muller suggested using the ratio of crossovers to the total of crossovers and noncrossovers ...
Hernia and Its Heredity - Iowa State University Digital Repository
... not accomplished, the skin is not strong enough to support the pressure of the abdominal viscera and a hernia results. Most types of hernia can be reduced surgically and, be it in livestock or man, recovery is generally well accomplished. It is not the purpose of this article to discuss such treatme ...
... not accomplished, the skin is not strong enough to support the pressure of the abdominal viscera and a hernia results. Most types of hernia can be reduced surgically and, be it in livestock or man, recovery is generally well accomplished. It is not the purpose of this article to discuss such treatme ...
D3.1 - transPLANT
... ENVO is a very general ontology maintained by known experts of bioontologies (S. Lewis, C. Mungall, M. Ashburner, B. Smith, …). ENVO contains terms for biomes, environmental features, and environmental material. The drawback of this general approach is that only a very small subset of the ontology m ...
... ENVO is a very general ontology maintained by known experts of bioontologies (S. Lewis, C. Mungall, M. Ashburner, B. Smith, …). ENVO contains terms for biomes, environmental features, and environmental material. The drawback of this general approach is that only a very small subset of the ontology m ...
Section 1 The application - Office of the Gene Technology Regulator
... The Gene Technology Act 2000 (the Act) and the Gene Technology Regulations 2001 (the Regulations) set out requirements which the Gene Technology Regulator (the Regulator) must follow when considering an application for a licence to intentionally release a genetically modified organism (GMO) into the ...
... The Gene Technology Act 2000 (the Act) and the Gene Technology Regulations 2001 (the Regulations) set out requirements which the Gene Technology Regulator (the Regulator) must follow when considering an application for a licence to intentionally release a genetically modified organism (GMO) into the ...
Calculating the Number of Genes
... – the population of haploid organisms is then screened for favorable traits, – the plants are then treated with colchicine which generates a 2n plant homozygous for the ...
... – the population of haploid organisms is then screened for favorable traits, – the plants are then treated with colchicine which generates a 2n plant homozygous for the ...
Different susceptibility of two animal species infected with isogenic
... has been determined in a single model of animal virulence, usually in mice or guinea pigs. This use of a single animal model reflects practicalities in terms of cost and time of using more than one animal host under biological containment for investigating a chronic disease, as well as an underlying ...
... has been determined in a single model of animal virulence, usually in mice or guinea pigs. This use of a single animal model reflects practicalities in terms of cost and time of using more than one animal host under biological containment for investigating a chronic disease, as well as an underlying ...
THE GENETICS OF CAENORΉABDITIS ELEGANS
... develop. In the same way, the isolation and genetical characterization of mutants with behavioral alterations must be supported by analysis at a level intermediate between the gene and behavior. Behavior is the result of a complex and ill-understood set of computations performed by nervous systems a ...
... develop. In the same way, the isolation and genetical characterization of mutants with behavioral alterations must be supported by analysis at a level intermediate between the gene and behavior. Behavior is the result of a complex and ill-understood set of computations performed by nervous systems a ...
GENETICS Lois E Brenneman, MSN, ANP, FNP, C Historical
... DNA , chrom osom e dam age, etc. with the end result that a particular trait is expressed “out of the blue.” W here this trait is favorable, it m ay offer the individual a selective advantage or the opposite situation where the trait is a handicap. Achondroplastic dwarfism can occur as an inherited ...
... DNA , chrom osom e dam age, etc. with the end result that a particular trait is expressed “out of the blue.” W here this trait is favorable, it m ay offer the individual a selective advantage or the opposite situation where the trait is a handicap. Achondroplastic dwarfism can occur as an inherited ...
Gene Section ATF2 (activating transcription factor 2) Atlas of Genetics and Cytogenetics
... ATF2 is one of 16 members of the ATF and CREB group of bZIP transcription factors, components of the activating protein 1 (AP-1). The canonical form of ATF2 is made of 505 amino acids, 54.537 kDa according to Swiss-Prot. ATF2 comprises from N-term to C-term a zinc finger (C2H2-type; DNA binding) (am ...
... ATF2 is one of 16 members of the ATF and CREB group of bZIP transcription factors, components of the activating protein 1 (AP-1). The canonical form of ATF2 is made of 505 amino acids, 54.537 kDa according to Swiss-Prot. ATF2 comprises from N-term to C-term a zinc finger (C2H2-type; DNA binding) (am ...
PPT
... For example: locus 1 is polymorphism in a transcription factor gene that affects protein binding affinity, locus 2 is in a binding site ...
... For example: locus 1 is polymorphism in a transcription factor gene that affects protein binding affinity, locus 2 is in a binding site ...
Product description P048-C1-0315 LMNA-MYOT - MRC
... polymorphism in the sequence detected by a probe can also cause a reduction in relative peak height, even when not located exactly on the ligation site! In addition, some probe signals are more sensitive to sample purity and small changes in experimental conditions. Therefore, deletions and duplicat ...
... polymorphism in the sequence detected by a probe can also cause a reduction in relative peak height, even when not located exactly on the ligation site! In addition, some probe signals are more sensitive to sample purity and small changes in experimental conditions. Therefore, deletions and duplicat ...
Baker, B. S., Hoff, G., Kaufman, T. C., Wolfner, M. W., and Hazelrigg, T. (1991). A cytopgenetic analysis of the doublesex locus and its flanking regions. Genetics 127: 125-138.
... affects female sexual differentiation, but only weakly affects male sexual differentiation. T h e interactions of ~ s x " ~ ~with ' * mutations in other genes affecting sexual differentiation are described. These results are discussed in terms of the recent molecular findings that the dsx locus enco ...
... affects female sexual differentiation, but only weakly affects male sexual differentiation. T h e interactions of ~ s x " ~ ~with ' * mutations in other genes affecting sexual differentiation are described. These results are discussed in terms of the recent molecular findings that the dsx locus enco ...
EXCHANGE OF GENETIC MATERIAL BETWEEN
... Hfr character, unlike the F+ character, is not transferable to F- cells by infection but can be transferred by conjugation (BERNSTEIN1958); in other words, the factor responsible for Hfr is located on the bacterial chromosome. An attempt was therefore made to introduce the Hfr character into Salmone ...
... Hfr character, unlike the F+ character, is not transferable to F- cells by infection but can be transferred by conjugation (BERNSTEIN1958); in other words, the factor responsible for Hfr is located on the bacterial chromosome. An attempt was therefore made to introduce the Hfr character into Salmone ...
Prof. Kamakaka`s Lecture 12 Notes
... Need to know mutation Need to look at genes of individuals Genes lie buried in 6billion base pairs of DNA (46 chromosomes). Molecular analyses necessary Take advantage of enzymes and reactions that naturally occur in bacteria ...
... Need to know mutation Need to look at genes of individuals Genes lie buried in 6billion base pairs of DNA (46 chromosomes). Molecular analyses necessary Take advantage of enzymes and reactions that naturally occur in bacteria ...
The genetics of Caenorhabditis elegans.
... (JUDD, SHENand KAUFMAN 1972). Although there are many theories suggesting how the extra DNA might be used for complex genetic regulation (BRITTEN and DAVIDSON 1969; GEORGIEV 1969; CRICK 1971), the problem is still opaque. We know very little about the molecular mechanisms used to switch genes on and ...
... (JUDD, SHENand KAUFMAN 1972). Although there are many theories suggesting how the extra DNA might be used for complex genetic regulation (BRITTEN and DAVIDSON 1969; GEORGIEV 1969; CRICK 1971), the problem is still opaque. We know very little about the molecular mechanisms used to switch genes on and ...
Randa Elfadil Ibrahim abdalla
... research for the financial support. To all those who encouraged me, I owe and gladly acknowledge a considerable debt. Finally, I would like to acknowledge and thank The National Ribat University. Abstract Introduction: Asthma is an inflammatory disease that results from interactions between multiple ...
... research for the financial support. To all those who encouraged me, I owe and gladly acknowledge a considerable debt. Finally, I would like to acknowledge and thank The National Ribat University. Abstract Introduction: Asthma is an inflammatory disease that results from interactions between multiple ...
Neisseria meningitidis: an overview of the carriage state
... rates of 1000/100 000 may be reached during severe epidemics in sub-Saharan Africa. The factors that lead to invasive disease are still poorly understood. However, noncarriers are considered as a high-risk group for meningococcal disease since their capability to maintain a commensal relationship wi ...
... rates of 1000/100 000 may be reached during severe epidemics in sub-Saharan Africa. The factors that lead to invasive disease are still poorly understood. However, noncarriers are considered as a high-risk group for meningococcal disease since their capability to maintain a commensal relationship wi ...
Ret/PTC3 is the most frequent form of gene rearrangement
... papillary thyroid carcinomas only for ret/PTC1 rearrangements and found no rearrangement; Ishizaka et al. (1991) found one ret/PTC1 rearrangement among 11 carcinomas, and Wajjwalku et al. (1992) found only one such alteration among 38 carcinomas. On the basis of those observations, RET gene rearrang ...
... papillary thyroid carcinomas only for ret/PTC1 rearrangements and found no rearrangement; Ishizaka et al. (1991) found one ret/PTC1 rearrangement among 11 carcinomas, and Wajjwalku et al. (1992) found only one such alteration among 38 carcinomas. On the basis of those observations, RET gene rearrang ...
Applied Biosystems Real-Time PCR Rapid Assay Development
... For real-time PCR assays designed following our Rapid Assay Development Guidelines, we recommend final reaction concentrations of 900nM for each primer and 250nM of the probe for Gene Expression, and 900nM of each primer and 200nM of each probe for SNP Genotyping assays. These recommendations will p ...
... For real-time PCR assays designed following our Rapid Assay Development Guidelines, we recommend final reaction concentrations of 900nM for each primer and 250nM of the probe for Gene Expression, and 900nM of each primer and 200nM of each probe for SNP Genotyping assays. These recommendations will p ...
PDF reprint - Stanford Medicine
... factors contribute to the development of diverse mesoderm-derived tissues is an important and largely unsolved question in cell type determination and organogenesis. Inductive interactions subdivide the early mesoderm into groups of cells that will give rise to the heart, somatic muscle, visceral mu ...
... factors contribute to the development of diverse mesoderm-derived tissues is an important and largely unsolved question in cell type determination and organogenesis. Inductive interactions subdivide the early mesoderm into groups of cells that will give rise to the heart, somatic muscle, visceral mu ...
BiochemicalSociety A nnualSymposium No.79
... derivative to the liver for the important degradative processes needed for cholesterol homoeostasis, and for its conversion into BAs, or for its conjugation to form glucuronide or sulfate metabolites with regulatory roles [38]. CYP46A1 is expressed in small amounts in the liver and testes and plays ...
... derivative to the liver for the important degradative processes needed for cholesterol homoeostasis, and for its conversion into BAs, or for its conjugation to form glucuronide or sulfate metabolites with regulatory roles [38]. CYP46A1 is expressed in small amounts in the liver and testes and plays ...
Document
... (Tab. III). Again, these observations cover many breeds and populations from Europe, China and Japan. A high level of PrP variation is therefore not unique to sheep. – Bovinae (cattle), Cervinae and Capriolinae (deer) In cattle (species Bos taurus, Bos indicus, Bos javanicus and Bos gruniens) there ...
... (Tab. III). Again, these observations cover many breeds and populations from Europe, China and Japan. A high level of PrP variation is therefore not unique to sheep. – Bovinae (cattle), Cervinae and Capriolinae (deer) In cattle (species Bos taurus, Bos indicus, Bos javanicus and Bos gruniens) there ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.