Xenopus Spinal Neurons Express Kv2 Potassium Channel
... yielding only one amino acid change (Fig. 1B). Because most of the nucleotide differences between the PCR products and the library cDNAs conserve the ainino acid sequence, it is unlikely that the PCR variants are attributable to random errors introduced by reverse transcriptase or Taq polymerase. It ...
... yielding only one amino acid change (Fig. 1B). Because most of the nucleotide differences between the PCR products and the library cDNAs conserve the ainino acid sequence, it is unlikely that the PCR variants are attributable to random errors introduced by reverse transcriptase or Taq polymerase. It ...
protein 2 gene: study of a cohort of Israeli patients - MRC
... variant, using clinical criteria established by Hagberg et al.4 The cohort also included four females with Angelman-like features and nine patients with diagnoses reminiscent of RTT, including seven females with autism spectrum disorder and two males with congenital severe encephalopathy. All the pa ...
... variant, using clinical criteria established by Hagberg et al.4 The cohort also included four females with Angelman-like features and nine patients with diagnoses reminiscent of RTT, including seven females with autism spectrum disorder and two males with congenital severe encephalopathy. All the pa ...
Attachment 2.2 Sequencing results
... The same pathway is activated when halogenated aromatic hydrocarbons, such as 2,3,7,8tetrachlorodibenzo-p-dioxin (TCDD) bind AHR. The heterocomplex again binds the XRE on the DNA in the promoter region of genes encoding Cytochrome P4501A1 (CYP1A1), 1A2 and 1B1. Unfortunately, the CYP1A1, 1A2 and 1B1 ...
... The same pathway is activated when halogenated aromatic hydrocarbons, such as 2,3,7,8tetrachlorodibenzo-p-dioxin (TCDD) bind AHR. The heterocomplex again binds the XRE on the DNA in the promoter region of genes encoding Cytochrome P4501A1 (CYP1A1), 1A2 and 1B1. Unfortunately, the CYP1A1, 1A2 and 1B1 ...
Final What is Thal. Trait
... CVS can be performed somewhat earlier than amniocentesis, at about 10-11 weeks of pregnancy. In this test, the doctor removes a small sample of the chorionic villi, or the cells that will form the placenta. The cells are removed either with a thin needle inserted in the mother’s abdomen or with a th ...
... CVS can be performed somewhat earlier than amniocentesis, at about 10-11 weeks of pregnancy. In this test, the doctor removes a small sample of the chorionic villi, or the cells that will form the placenta. The cells are removed either with a thin needle inserted in the mother’s abdomen or with a th ...
What is Cholesterol?......cont. - Home
... Unused LDL • The regulated receptors on the liver will help return some of the cholesterol to the liver from unused LDL. . • LDL is the so-called “bad cholesterol” and genetic differences in these regulated receptors can result in the accumulation or large amounts of LDL in the circulation (familial ...
... Unused LDL • The regulated receptors on the liver will help return some of the cholesterol to the liver from unused LDL. . • LDL is the so-called “bad cholesterol” and genetic differences in these regulated receptors can result in the accumulation or large amounts of LDL in the circulation (familial ...
Tapanes-Castillo A, Weaver EJ, Smith RP, Kamei Y, Caspary T, Hamilton-Nelson KL, Slifer SH, Martin ER, Bixby JL, Lemmon VP. Neurogenetics. 2012 Feb;11(1):53-71. A modifier locus on chromosome 5 contributes to L1 cell adhesion molecule X-linked hydrocephalus in mice.
... differences in brain size and standardize measurements, a ratio was calculated for each brain: total lateral ventricular area divided by coronal section area. Ratios were then transformed, using a natural log scale [ln (1,000×ratio)], to approximate a normal distribution for statistical analyses. We ...
... differences in brain size and standardize measurements, a ratio was calculated for each brain: total lateral ventricular area divided by coronal section area. Ratios were then transformed, using a natural log scale [ln (1,000×ratio)], to approximate a normal distribution for statistical analyses. We ...
The landscape of Neandertal ancestry in present
... onto the modern human genetic background that were not tolerated and were swept away, in part because they contributed to male hybrid sterility. The resulting reduction in Neandertal ancestry was quantitatively large: in the fifth of the genome with highest B, Neandertal ancestry is 1.54 ± 0.15 time ...
... onto the modern human genetic background that were not tolerated and were swept away, in part because they contributed to male hybrid sterility. The resulting reduction in Neandertal ancestry was quantitatively large: in the fifth of the genome with highest B, Neandertal ancestry is 1.54 ± 0.15 time ...
Chromosomal Aberration of the 11q23 Locus in Acute Leukemia
... marked biologic heterogeneity of 11q23 aberrations. Furthermore, because many v11q23 translocations are rare translocations, the clinical impact of specific single variants is difficult to extrapolate, even from large studies on 11q23 AL.14-16 Recently, the combined use of conventional cytogenetics, ...
... marked biologic heterogeneity of 11q23 aberrations. Furthermore, because many v11q23 translocations are rare translocations, the clinical impact of specific single variants is difficult to extrapolate, even from large studies on 11q23 AL.14-16 Recently, the combined use of conventional cytogenetics, ...
The growth hormone auxin
... Auxin biosynthesis 1. Necessary for determining the physiological roles of auxin 2. Necessary for understanding auxin movements and dynamics 3. Provides genetic foundations for dissecting the mechanisms of auxin in plant development ...
... Auxin biosynthesis 1. Necessary for determining the physiological roles of auxin 2. Necessary for understanding auxin movements and dynamics 3. Provides genetic foundations for dissecting the mechanisms of auxin in plant development ...
Assessing the role of anammox in a nitrogen contaminated aquifer
... main concerns about DNRA is that NO3- is transformed into another mineral N form which is less mobile and may conserve N in the ecosystem, unlike denitrification (Buresh and Patrick, 1978; Tiedje, 1988). King and Nedell (1985) determined that DNRA may occur in areas with elevated concentrations of o ...
... main concerns about DNRA is that NO3- is transformed into another mineral N form which is less mobile and may conserve N in the ecosystem, unlike denitrification (Buresh and Patrick, 1978; Tiedje, 1988). King and Nedell (1985) determined that DNRA may occur in areas with elevated concentrations of o ...
WUSCHEL signaling functions in interregional communication
... hybridization signal was observed in the epithelium of mature ovules (data not shown). Because we frequently observed a high background signal in the epithelium with various probes, this signal probably does not reflect specific WUS expression. In addition to its expression in ovules, WUS mRNA was a ...
... hybridization signal was observed in the epithelium of mature ovules (data not shown). Because we frequently observed a high background signal in the epithelium with various probes, this signal probably does not reflect specific WUS expression. In addition to its expression in ovules, WUS mRNA was a ...
allJoiner
... -identifier=name - Just validate given identifier. -database=name - Just validate given database. -fields - Check fields in joiner file exist, faster with -fieldListIn -fieldListOut=file - List all fields in all databases to file. -fieldListIn=file - Get list of fields from file rather than mysql. - ...
... -identifier=name - Just validate given identifier. -database=name - Just validate given database. -fields - Check fields in joiner file exist, faster with -fieldListIn -fieldListOut=file - List all fields in all databases to file. -fieldListIn=file - Get list of fields from file rather than mysql. - ...
Methods Five 1536-SNP GoldenGate assays (Fig. 1) Three pilot
... more often than with relatively stringent settings of p = 95, d = 60, f = 100, h = 50 which were used for assembly #21. SNPs were identified from 36 pairwise comparisons of ESTs from eight malting barley cultivars (Akashinriki, Barke, Golden Promise, Haruna Nijo, Kymppi, Morex, Optic, Saana) and one ...
... more often than with relatively stringent settings of p = 95, d = 60, f = 100, h = 50 which were used for assembly #21. SNPs were identified from 36 pairwise comparisons of ESTs from eight malting barley cultivars (Akashinriki, Barke, Golden Promise, Haruna Nijo, Kymppi, Morex, Optic, Saana) and one ...
ontology design patterns for the formalisation of biological ontologies
... of the knowledge about a given domain, allowing computers to manage the information in a semantic level. The most successful ontologies applied in Bioinformatics are the ones in the Open Biomedical Ontologies (OBO) project. Most of the OBO ontologies are very simple and intuitive but lack formality ...
... of the knowledge about a given domain, allowing computers to manage the information in a semantic level. The most successful ontologies applied in Bioinformatics are the ones in the Open Biomedical Ontologies (OBO) project. Most of the OBO ontologies are very simple and intuitive but lack formality ...
Mining MIM: phenotype clustering as source of candidate
... genetic modification. In short, any means to link phenotypes to candidate genes will be most valuable. But even if we do not know the genetic underpinnings of a particular phenotype, this does not imply we know nothing at all about its cause. Similar phenotype characteristics are likely to result fr ...
... genetic modification. In short, any means to link phenotypes to candidate genes will be most valuable. But even if we do not know the genetic underpinnings of a particular phenotype, this does not imply we know nothing at all about its cause. Similar phenotype characteristics are likely to result fr ...
ADRC2010_GetTheMostOutofFlyBase
... particular subject/class, organized into a hierarchical tree • Tree structure indicates how each specific CV term relates to others within that particular vocabulary • aka ‘ontologies’ ...
... particular subject/class, organized into a hierarchical tree • Tree structure indicates how each specific CV term relates to others within that particular vocabulary • aka ‘ontologies’ ...
Auxin metabolism and homeostasis during plant development
... pathways were missing and the regulation of auxin metabolism was poorly understood, but genetic and biochemical evidence in combination with sensitive methods for auxin metabolite identification and quantification have greatly improved our knowledge in this respect. This Primer describes the recent ...
... pathways were missing and the regulation of auxin metabolism was poorly understood, but genetic and biochemical evidence in combination with sensitive methods for auxin metabolite identification and quantification have greatly improved our knowledge in this respect. This Primer describes the recent ...
Coffee B, Ikeda M, Budimirovic DB, Hjelm LN, Kaufmann WE and Warren ST: Mosaic FMR1 Deletion Causes Fragile X Syndrome and Can Lead to Molecular Misdiagnosis: A Case Report and Review of the Literature. American J of Medical Genetics Part A 146A:1358-1367 (2008).
... of a CGG trinucleotide repeat in the 50 UTR of FMR1. This expansion leads to transcriptional silencing of the gene. However, other mutational mechanisms, such as deletions of FMR1, also cause fragile X syndrome. The result is the same for both the expansion mediated silencing and deletion, absence o ...
... of a CGG trinucleotide repeat in the 50 UTR of FMR1. This expansion leads to transcriptional silencing of the gene. However, other mutational mechanisms, such as deletions of FMR1, also cause fragile X syndrome. The result is the same for both the expansion mediated silencing and deletion, absence o ...
Introduction to Genetics
... Associates/Science Source Photo Researchers; bottom, courtesy of Eric Lander, Whitehead Institute, MIT.) ...
... Associates/Science Source Photo Researchers; bottom, courtesy of Eric Lander, Whitehead Institute, MIT.) ...
BT314 Virology
... Associates/Science Source Photo Researchers; bottom, courtesy of Eric Lander, Whitehead Institute, MIT.) ...
... Associates/Science Source Photo Researchers; bottom, courtesy of Eric Lander, Whitehead Institute, MIT.) ...
Neurospora Spore Killers Sk-2 and Sk
... of the tetrad give rise to round ascospores; even those nuclei that contain a wild-type allele are round. The cause of dominance is probably rearrangements and/or deletions that prevent the wild-type allele from pairing with a homolog. MSUD is implicated in these ascusdominant phenotypes of these mu ...
... of the tetrad give rise to round ascospores; even those nuclei that contain a wild-type allele are round. The cause of dominance is probably rearrangements and/or deletions that prevent the wild-type allele from pairing with a homolog. MSUD is implicated in these ascusdominant phenotypes of these mu ...
The importance of genetic influences in asthma REVIEW H. Los* , G.H. Koppelman*
... the control group, only 1% [29]. In 1980, SIBBALD et al. [30] described 77 asthmatic and 87 control children and their relatives. The overall prevalence of asthma in the first degree relatives of asthmatics was 13%, and that in the relatives of controls only 4%. The prevalence of ...
... the control group, only 1% [29]. In 1980, SIBBALD et al. [30] described 77 asthmatic and 87 control children and their relatives. The overall prevalence of asthma in the first degree relatives of asthmatics was 13%, and that in the relatives of controls only 4%. The prevalence of ...
inactivation of the odontogenic ameloblast
... and Novick, 1997; Wade-Gueye et al., 2010; Yoshitake et al., 1999), we have therefore challenged our Odam KO mice by (1) placing them for extended periods of time in a conventional non-sterile vivarium (replicating conditions leading to periodontal disease) and (2) injuring the JE by gingivectomy to ...
... and Novick, 1997; Wade-Gueye et al., 2010; Yoshitake et al., 1999), we have therefore challenged our Odam KO mice by (1) placing them for extended periods of time in a conventional non-sterile vivarium (replicating conditions leading to periodontal disease) and (2) injuring the JE by gingivectomy to ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.