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Full-Text PDF
Full-Text PDF

... because the variety that is at the basis of the cisgenic event has a history of safe use, whereas the resistant new variety obtained through conventional breeding still has to prove its safety. In the optimal scenario, different varieties with different combinations of LBR genes should either be alt ...
The alphabet soup of plant intracellular signalling: enter cyclic
The alphabet soup of plant intracellular signalling: enter cyclic

... phenotype is reminiscent of the Arabidopsis cytokinin resistant mutant cyr1 [38], though does not appear to be allelic to it. The authors suggest GCR1 is involved in cytokinin signalling. The question of course is how direct, or indirect, this involvement might be. Previously, CKI1 has been isolated ...
Integrated genomic DNA/RNA profiling of
Integrated genomic DNA/RNA profiling of

... with similar accuracy to lower-throughput assays that focus on specific genes and types of genomic alterations. Profiling of 3696 samples identified recurrent somatic alterations that impact diagnosis, prognosis, and therapy selection. This comprehensive genomic profiling approach has proved effecti ...
PTC Genes and Bitter Taste
PTC Genes and Bitter Taste

...  Complete the pedigree on the back and answer the questions that go along with it. Website Questions: 1. Who was the scientist that discovered the PTC taste variation among people? ...
Oncogene (2005)
Oncogene (2005)

... presence/absence of entire exons or in different exon boundaries and representing a significant percentage of all mRNA transcripts. Alternative splicing has an important role in expanding protein diversity and it is now well established that many human genes are alternatively spliced. The presence of ...
Variation and Inheritance – Revision Pack (B1) Inherited
Variation and Inheritance – Revision Pack (B1) Inherited

September 2006 - University of Maryland School of Medicine
September 2006 - University of Maryland School of Medicine

... to have them contact us. My staff and I would like to thank you and your family for your valuable time and dedication to our research. Through our research, we have helped numerous people to improve their health and thus the quality and quantity of their lives. In addition, your participation will o ...
Genome-Wide Identification of Allelic Expression in Hypertensive Rats
Genome-Wide Identification of Allelic Expression in Hypertensive Rats

... by polymorphism in the gene that we detected. Resequencing Sod1 in the 2 rat strains across the RGU34A hybridization probes revealed an insertion-deletion polymorphism in the transcribed sequence from which differential array hybridization signals arose. We screened all genes in Table 2 by dHPLC for ...
Benefits of being biased! - Indian Academy of Sciences
Benefits of being biased! - Indian Academy of Sciences

... Drosophila melanogaster, the fitness effects might be too small to be observed. Two recent studies (Carlini and Stephan 2003; Carlini 2004) show that even in such systems, under certain conditions, it is possible to empirically demonstrate the effects of codon bias at the phenotypic level, and the c ...
Asian Journal of Multidisciplinary Studies
Asian Journal of Multidisciplinary Studies

... are structures in ach cell that convert molecules into energy, each contain a small amount of DNA. ...
Cooccurrence of distinct ciliopathy diseases in single families
Cooccurrence of distinct ciliopathy diseases in single families

... unilateral postaxial polydactyly and nystagmus with visual reduction although fundus examination and ERG were normal. MRI showed mild cerebellar vermis hypoplasia without the MTS evident (Supplemental Fig. 1). After the death of the mother, the father remarried a woman from the same small village, s ...
Chapter 29
Chapter 29

... – Act directly on DNA, other RNAs, or proteins – Inactivate transposons, genes that tend to replicate themselves and disable or hyperactivate other genes – Control timing of apoptosis during development – Prevent translation of another gene – Mutations linked to prostate and lung cancers, and schizo ...
Lectures 12 - 13 Genetics of Human Disease: Hemoglobinopathies
Lectures 12 - 13 Genetics of Human Disease: Hemoglobinopathies

... government health-expenditures. • 183 / 591 (31%) of persons in families with an index case tested were carriers • All carriers reported using the information provided in counseling • “Testing of extended families is a feasible way of deploying DNA-based genetic screening in communities in which con ...
B M B 400 Part Four
B M B 400 Part Four

... A seminal observation in the correlation of gene activity with more accessible chromatin was the demonstration that transcriptionally active genes are found in chromatin that is more sensitive to DNases. Weintraub and Groudine showed in 1976 that the overall sensitivity of a gene to DNase I is incre ...
Meiosis II - Cloudfront.net
Meiosis II - Cloudfront.net

... ****This is true if the traits you are studying are located on different chromosomes Just by chance all 7 of Mendel’s traits were on different chromosomes. ...
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))

... apoptosis and transformation. JUN promotes cell cycle transition from G1 phase to S phase by up-regulating cyclin D1 expression and antagonizing the function of p53and p21. The JUN protein is involved in both the induction and prevention of apoptosis, possibly dependent on the types and development ...
Haemoglobinopathies in Southeast Asia
Haemoglobinopathies in Southeast Asia

... fetalis at 18-20 wk of pregnancy22. DNA diagnosis from chorionic villi or amniotic fluid fibroblasts can detect Hb Bart’s hydrops fetalis as early as 10-16 wk gestation23. Therapeutic abortion is suggested for the foetus diagnosed as having this disease. Hb H disease Usually the patients have no s ...
EXTENSIONS AND DEVIATIONS OF MENDELIAN INHERITANCE
EXTENSIONS AND DEVIATIONS OF MENDELIAN INHERITANCE

... Two different highly inbred strains are crossed „ The hybrids may display traits superior to both parents „ This phenomenon is termed hybrid vigor or heterosis Heterosis is used to improve quantitative traits such as size, weight and growth rate Heterosis is different from overdominance, because it ...
RealTime ready Cell Lysis Kit
RealTime ready Cell Lysis Kit

... represents a beneficial building block in the pathway of gene expression analysis by providing significant time savings combined with increased convenience for low- to medium-throughput, real-time PCR applications. Together with the Transcriptor Universal cDNA Master, with its ...
Quantitative Genetics
Quantitative Genetics

... has, the greater their potential for growing tall Additive alleles behave something like alleles that result in incomplete dominance More CR alleles results in F2 Generation ...
Problem set questions from Exam 3 – Eukaryotic Gene Regulation
Problem set questions from Exam 3 – Eukaryotic Gene Regulation

... (f) In light of the experiments from parts (a) – (e), propose a specific function for any cisacting segment that has a clear regulatory role as defined by these deletion constructs. (g) What two conclusions can you draw from the fact that deletions #3 - #5 show normal regulation of Prad66–LacZ? ...
user`s guide
user`s guide

... This product contains the inventory of rare disorders listed in the Orphanet database and the associated genes (pathogenic and susceptibility genes). Each gene is described by its official name, synonyms, type and location, defined by the HUGO Gene Nomenclature Committee (HGNC). Genes are mapped wit ...
Biology 40S Genetics Booklet (StudentsCopy2)
Biology 40S Genetics Booklet (StudentsCopy2)

... • If both parents have brown eyes, what colour of eyes do you think the children will inherit? • If one parent had an accident and lost a finger (has only nine fingers), how many fingers will that person's children inherit? • If one parent decides to get into shape by lifting weights and develops la ...
Leukaemia Section t(11;11)(q13;q23) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(11;11)(q13;q23) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... control of her karyotype revealed a t(11;11)(q13;q23), in the absence of any sign of leukemia in the bone marrow, over a period of 30 months following the discover of the t(11;11). Other cases of t(11;11)(q13;q23) were: A 13-year-old girl, who have had a M4eo AML with inv(16)(p13q22). ...
View Full Text-PDF
View Full Text-PDF

... Widespread of this gene in P. aeruginosa ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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