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Table 7. Summary statistics for the consensus gene set of Haliotis
Table 7. Summary statistics for the consensus gene set of Haliotis

... discus hannai was 1.86 Gb, and this is the biggest genome among known gastropods. It is 5.31 and 2.02 times larger than genomes size of L.gigantea (0.35 Gb) and A.californica (0.92 Gb) in the same Gastropoda class. In animals, the increase of genome size is commonly driven by transposable element, ...
Inquiry into Life Twelfth Edition
Inquiry into Life Twelfth Edition

... – Can be converted to IIb by proteolytic removal of the carboxylterminal domain (CTD) which is 7aa-peptide repeated over and over. Enzyme with IIa binds to the promoter – Converts to IIo by phosphorylating 2 ser in the repeating heptad of the CTD. Enzyme with IIo is involved in transcript elongation ...
Quorum Sensing in Gram-negative and Gram-positive
Quorum Sensing in Gram-negative and Gram-positive

... The ComD is a sensor kinase protein which detects the accumulated CSP at higher cell density. ComD is a membrane bound receptor/kinase and functions through the response regulator ComE communicating CSP abundance to responder genes. Higher than the threshold levels of CSP induce auto phosphorylation ...
pr - vg
pr - vg

... Using 2 analysis to explore linkage Is this really a 1:1:1:1 ratio as we would expect for independent assortment? Is the deviation from independent assortment due to chance? 2 analysis: Test the “null” hypothesis—that the observed deviation from 1:1:1:1 segregation is due to chance variation. ...
Formal Genetics of Humans: Modes of Inheritance
Formal Genetics of Humans: Modes of Inheritance

... • Duplication of autosomal recessive alleles: In isodisomy, two copies of a mutant allele would result in the disease phenotype. In the originally described case of maternal UPD7, cystic fibrosis was due to two maternally derived copies of the Gly542Ter mutation of the CFTR genes (the mother in that ...
BSU Reading Guide Ch 10 Genetics
BSU Reading Guide Ch 10 Genetics

... (figure 10.1). Crossing pea plants with one another, Mendel made observations that allowed him to form a simple but powerful hypothesis that accurately predicted patterns of heredity—that is, how many offspring would be like one parent and how many like the other. When Mendel's rules, introduced in ...
The vertebrate genome annotation (Vega) database
The vertebrate genome annotation (Vega) database

... and zebrafish, are being fully sequenced and finished to a quality which merits manual annotation. Although labour intensive and relatively slow compared with automatic annotation methods, manual annotation provides an invaluable reliable reference resource that can be used to predict gene structures ...
Suppression mechanisms
Suppression mechanisms

... methods ultimately requires multiple types of mutant selections to identify all the genes involved in that process. One strategy commonly used to identify functionally related genes is to begin with a strain that already contains a mutation affecting the pathway of interest, selecting for mutations ...
Correlation of length of VNTR alleles at the X
Correlation of length of VNTR alleles at the X

... the effects were major, they would result in single gene rather than polygenic disorders. X-linked genes form a unique vehicle to examine this hypothesis and search for subtle effects since, at least in males, each allele is hemizygously present thus eliminating the confounding factor of heterozygos ...
Pathways - Bioinformatics.ca
Pathways - Bioinformatics.ca

... Co-expression within pathways • Tempting thought: genes that occur within the same pathway will show similar expression profiles • Reality: depends greatly on how you identify your pathways, KEGG pathways show at best 50% coexpression in survey of available yeast expression data (Ihmels et al., Nat ...
Sense and Nonsense in the Genetic Code
Sense and Nonsense in the Genetic Code

... of the genes; only the genes located along one direction from the mutation usually are affected (17) Thls is the expected result-for rLonsensemutations which act as shown in Fig. 2 but it is not a proof of the postulated mechanisme Pleiotropic mutations have also been described for an RNA phageS in ...
MAGMA manual (version 1.06)
MAGMA manual (version 1.06)

... header) or index, so for example adding ‘use=rsid,6’ will look for SNP IDs in the column named ‘rsid’, and for p-values in the sixth column. The N and ncol modifiers are used to specify the sample size. The N modifier is used to specify the sample size directly (the total sample size, also when usin ...
Restriction fragment differential display of pediocin
Restriction fragment differential display of pediocin

... We have developed the so-called restriction fragment differential display PCR (RFDD-PCR) which is a variation of the cDNA amplified fragment length polymorphism DD technique originally described by Bachem et al. (1996). The technology is based on digesting cDNA with endonucleases followed by adaptor ...
Genes for personality traits - Oxford Academic
Genes for personality traits - Oxford Academic

... This approach is most powerful when candidate genes that are ‘ biologically reasonable ’, and that have known functional polymorphisms, are available. The main advantage of allelic association is that it is remarkably sensitive to small effect sizes. Until recently, there had been no published repor ...
A Paint Horse owner`s guide to demystifying the genetics of spotting
A Paint Horse owner`s guide to demystifying the genetics of spotting

... “The analogy [for Paints] is that LP is like Tobiano and PATN1 is your mythical enhancement gene,” she said. “The reality is that because Paint Horses work with so many different patterns, we probably don’t have an enhancement gene. But why else would you get some horses that are 80 percent white an ...
PowerPoint
PowerPoint

... Consider the codons specifying aspartic acid and lysine: both start AA, lysine ends A or G, and aspartic acid ends T or C. So, if the rate at which C changes to T is higher from the rate that C changes to G or A (as is often the case), then more of the changes at the third position will be synonymou ...
Presentation
Presentation

... mom and dad - that’s why you look like a combination of them and not your pet hamster. That is, unless your parents were hamsters! © Getting Nerdy, LLC ...
Microarray Data Analysis for Detection and Classification of Viral
Microarray Data Analysis for Detection and Classification of Viral

... blotting. The most important stage in this technology is data analysis. To analysis such large data whit high degree of confidence and reliability needs reliable bioinformatics tools.Infectious diseases still is major problem for human. One of the most important application of microarray technology ...
Biology 1/e
Biology 1/e

... HbSHbS Homozygote ...
Approaches to gene mapping in complex disorders and their
Approaches to gene mapping in complex disorders and their

... very close to such functional variants. So far 60 000 of the identified SNPs fall within protein coding sequences and 85% of coding regions are within 5000 base pairs of the nearest SNP. It has been estimated that a systematic approach to cataloguing all the variation that may be relevant to human b ...
NCBI: what is new? - medicalintelligence.org
NCBI: what is new? - medicalintelligence.org

... Biotechnology Information as part of National Library of Medicine at NIH. ...
Clustering of mandibular organ-inhibiting hormone and moult
Clustering of mandibular organ-inhibiting hormone and moult

... directly or following sub-cloning into Bluescript vector) by using M13 forward and reverse primers, together with gene-specific primers. In addition, the sequence of continuous regions of 8.5 kb from a representative group 1 clone (l1) and 4.3 kb from a representative group 4 clone (l12) were determ ...
Expressway Plus - Thermo Fisher Scientific
Expressway Plus - Thermo Fisher Scientific

... High-performance protein expression Traditional protein expression systems involve expressing recombinant proteins in intact eukaryotic or prokaryotic cells. Although effective, these methods can be both time-consuming and technically challenging. The Expressway™ Plus Expression System eliminates t ...
PPT File
PPT File

... The average gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene being dystrophin at 2.4 million bases. The total number of genes is estimated at 30,000 ...
Leukaemia Section t(3;12)(q26;p13) ETV6/MECOM / t(3;12)(q26;p13) ETV6/EVI1 Atlas of Genetics and Cytogenetics
Leukaemia Section t(3;12)(q26;p13) ETV6/MECOM / t(3;12)(q26;p13) ETV6/EVI1 Atlas of Genetics and Cytogenetics

... two start codons, one (exon 1a starting at codon 1) located at the beginning of the gene and another alternative (exon 1b starting at codon 43) upstream of exon 3. Protein The ETV6 protein (452 amino acids) contains two major domains, the HLH (helix-loop-helix) and ETS domains. The HLH domain, also ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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