repetitive extragenic palindromic sequences in pseudomonas
... following negatively oriented REP sequences shared another sequence Considering the conserved palindromy of REP sequences and the conserved arrangement of the clusters it is probable that REP sequences adopt conformations with peculiar secondary structures especially suitable to be specifically reco ...
... following negatively oriented REP sequences shared another sequence Considering the conserved palindromy of REP sequences and the conserved arrangement of the clusters it is probable that REP sequences adopt conformations with peculiar secondary structures especially suitable to be specifically reco ...
Poster - Pacific Biosciences
... Sample 1 was enriched using the Roche NimbleGen SeqCap EZ method and subsequently phased and typed at the HLADQA1 locus. The same sample was independently typed using sequence data from a Sanger-based assembly. Each method produced the identical type. ...
... Sample 1 was enriched using the Roche NimbleGen SeqCap EZ method and subsequently phased and typed at the HLADQA1 locus. The same sample was independently typed using sequence data from a Sanger-based assembly. Each method produced the identical type. ...
Scholarship Biology (93101) 2014
... Over thousands of years, humans have selectively bred all the breeds known today from a small population of original dogs. While some breeds were developed hundreds, or even thousands of years ago, most breeds have been developed only in the last 100 years. One of the older breeds is the British bul ...
... Over thousands of years, humans have selectively bred all the breeds known today from a small population of original dogs. While some breeds were developed hundreds, or even thousands of years ago, most breeds have been developed only in the last 100 years. One of the older breeds is the British bul ...
Analysis of genetic structure in Slovak Pinzgau cattle using five
... ARORA et al., 2010). Analysis of milk proteins polymorphism provides useful information to both the breeders and processors of milk. Many research reports have indicated that certain milk protein variants may be associated with milk production, milk composition (ROBITAILLE et al., 2002) and cheese p ...
... ARORA et al., 2010). Analysis of milk proteins polymorphism provides useful information to both the breeders and processors of milk. Many research reports have indicated that certain milk protein variants may be associated with milk production, milk composition (ROBITAILLE et al., 2002) and cheese p ...
A strategy for extracting and analyzing large
... size was measured in six replicates (two duplicate measurements on each of three independent experimental plates), allowing a natural measure of variation in the standard deviation. However, the standard deviation is only an estimate of experimental variability, and, with a relatively small number ...
... size was measured in six replicates (two duplicate measurements on each of three independent experimental plates), allowing a natural measure of variation in the standard deviation. However, the standard deviation is only an estimate of experimental variability, and, with a relatively small number ...
Vectors: The carriers of DNA molecules DNA vectors and their
... sequences between those sites, are known as replacement vectors. Apparently if too much non-essential DNA is deleted from the genome it cannot be packaged into phage particles efficiently. For both types of vector, the final recombinant genome must be between 39 and 52 kb of the wild type phage geno ...
... sequences between those sites, are known as replacement vectors. Apparently if too much non-essential DNA is deleted from the genome it cannot be packaged into phage particles efficiently. For both types of vector, the final recombinant genome must be between 39 and 52 kb of the wild type phage geno ...
Compound leaves: equal to the sum of their parts?
... (stm) and knotted1 (kn1) in Arabidopsis and maize, respectively, result in plants that are unable to maintain a SAM (Long et al., 1996; Vollbrecht et al., 2000). Maize plants that misexpress KNOX1 genes outside of their normal domain have ectopic proliferation of tissue in leaves, described as knots ...
... (stm) and knotted1 (kn1) in Arabidopsis and maize, respectively, result in plants that are unable to maintain a SAM (Long et al., 1996; Vollbrecht et al., 2000). Maize plants that misexpress KNOX1 genes outside of their normal domain have ectopic proliferation of tissue in leaves, described as knots ...
Chapter 25.
... An unexpected family tree. What are the evolutionary relationships among a human, a mushroom, and a tulip? Molecular systematics has revealed that— ...
... An unexpected family tree. What are the evolutionary relationships among a human, a mushroom, and a tulip? Molecular systematics has revealed that— ...
rolduc meeting. feel connected!
... There are many good reasons for the organizers to choose the theme: ‘feel connected’. First and foremost it symbolizes our aim to make all participants at the Retreat feel part of the ever expanding human genetics family. This family comprises ‘veterans’, but also many new PhD students from the diff ...
... There are many good reasons for the organizers to choose the theme: ‘feel connected’. First and foremost it symbolizes our aim to make all participants at the Retreat feel part of the ever expanding human genetics family. This family comprises ‘veterans’, but also many new PhD students from the diff ...
Supplementary Material
... examined animals heterozygous for the ok487 allele and a deficiency, sDf23, which deletes the hlh-17/hlh-31 locus (data not shown). We found that these animals were viable, suggesting that ok487 is unlikely to be a loss-of-function mutation in hlh-17. Finally, by sequencing the hlh-17/hlh-31 locus f ...
... examined animals heterozygous for the ok487 allele and a deficiency, sDf23, which deletes the hlh-17/hlh-31 locus (data not shown). We found that these animals were viable, suggesting that ok487 is unlikely to be a loss-of-function mutation in hlh-17. Finally, by sequencing the hlh-17/hlh-31 locus f ...
pdf
... regions to consider, with 51 unique flanking genes. There are 6 super-regions with at least 99 bp overlapping with ultra-conserved elements. At least one of the flanking genes for each of these 6 super-regions is a transcription factor located 1–314 kb away (IRX3, IRX5, IRX6, HOXD13, DMRT1, DMRT3, F ...
... regions to consider, with 51 unique flanking genes. There are 6 super-regions with at least 99 bp overlapping with ultra-conserved elements. At least one of the flanking genes for each of these 6 super-regions is a transcription factor located 1–314 kb away (IRX3, IRX5, IRX6, HOXD13, DMRT1, DMRT3, F ...
Emerging model systems in evo-devo: cavefish and microevolution
... lens vesicle, optic cup, and neural retina are initially formed in cavefish but the embryonic eye subsequently arrests in growth, degenerates, and disappears into the orbit (Fig. 1, O and P; Langecker et al. 1993; Jeffery et al. 2000; Yamamoto and Jeffery 2000). The cavefish eye primordium is smaller th ...
... lens vesicle, optic cup, and neural retina are initially formed in cavefish but the embryonic eye subsequently arrests in growth, degenerates, and disappears into the orbit (Fig. 1, O and P; Langecker et al. 1993; Jeffery et al. 2000; Yamamoto and Jeffery 2000). The cavefish eye primordium is smaller th ...
Archives of Microbiology
... Vanadium nitrogenase · Cyanobacteria · Tungsten · vnfDG · vnfH · Uptake hydrogenase · Gene expression Abbreviations ARA Acetylene reduction assay RT Reverse transcription ...
... Vanadium nitrogenase · Cyanobacteria · Tungsten · vnfDG · vnfH · Uptake hydrogenase · Gene expression Abbreviations ARA Acetylene reduction assay RT Reverse transcription ...
Molecular biology of brain aging and neurodegenerative disorders
... GENETIC APPROACHES TO STUDY LONGEVITY Several different methods can be used to identify genes that influence the human life-span. One of these is "case control" studies (Cox et al. 1989). In the latter, allele and genotype frequencies at poly- ...
... GENETIC APPROACHES TO STUDY LONGEVITY Several different methods can be used to identify genes that influence the human life-span. One of these is "case control" studies (Cox et al. 1989). In the latter, allele and genotype frequencies at poly- ...
5 The Genetics of Bacteria and Their Viruses
... (penr). How would you locate the locus for pen on the bacterial chromosome with respect to arg, ala, glu, pro, and leu? Formulate your answer in logical, well-explained steps and draw explicit diagrams where possible. Answer: First, carry out a series of crosses in which you select in a long mating ...
... (penr). How would you locate the locus for pen on the bacterial chromosome with respect to arg, ala, glu, pro, and leu? Formulate your answer in logical, well-explained steps and draw explicit diagrams where possible. Answer: First, carry out a series of crosses in which you select in a long mating ...
Investigation of Four Genes Responsible for Autosomal Recessive
... the water-soluble lens proteins. They have a particular spatial arrangement critical to the transparency of the lens and are hence good candidate genes for congenital cataract disease [26]. To our knowledge, there are only six previous reports of CRYBB1 mutations in patients with congenital cataract ...
... the water-soluble lens proteins. They have a particular spatial arrangement critical to the transparency of the lens and are hence good candidate genes for congenital cataract disease [26]. To our knowledge, there are only six previous reports of CRYBB1 mutations in patients with congenital cataract ...
Inquiry into Life Twelfth Edition
... – Can be converted to IIb by proteolytic removal of the carboxylterminal domain (CTD) which is 7aa-peptide repeated over and over. Enzyme with IIa binds to the promoter – Converts to IIo by phosphorylating 2 ser in the repeating heptad of the CTD. Enzyme with IIo is involved in transcript elongation ...
... – Can be converted to IIb by proteolytic removal of the carboxylterminal domain (CTD) which is 7aa-peptide repeated over and over. Enzyme with IIa binds to the promoter – Converts to IIo by phosphorylating 2 ser in the repeating heptad of the CTD. Enzyme with IIo is involved in transcript elongation ...
PDF
... during Xenopus gastrulation. They show that this process involves cell reorientation in response to a long-range platelet-derived growth factor A (PDGF-A) signal and directional intercellular migration towards the ectoderm, the source of this signal. The PCM, they report, fails to spread during gast ...
... during Xenopus gastrulation. They show that this process involves cell reorientation in response to a long-range platelet-derived growth factor A (PDGF-A) signal and directional intercellular migration towards the ectoderm, the source of this signal. The PCM, they report, fails to spread during gast ...
Table 7. Summary statistics for the consensus gene set of Haliotis
... discus hannai was 1.86 Gb, and this is the biggest genome among known gastropods. It is 5.31 and 2.02 times larger than genomes size of L.gigantea (0.35 Gb) and A.californica (0.92 Gb) in the same Gastropoda class. In animals, the increase of genome size is commonly driven by transposable element, ...
... discus hannai was 1.86 Gb, and this is the biggest genome among known gastropods. It is 5.31 and 2.02 times larger than genomes size of L.gigantea (0.35 Gb) and A.californica (0.92 Gb) in the same Gastropoda class. In animals, the increase of genome size is commonly driven by transposable element, ...
PDF
... during Xenopus gastrulation. They show that this process involves cell reorientation in response to a long-range platelet-derived growth factor A (PDGF-A) signal and directional intercellular migration towards the ectoderm, the source of this signal. The PCM, they report, fails to spread during gast ...
... during Xenopus gastrulation. They show that this process involves cell reorientation in response to a long-range platelet-derived growth factor A (PDGF-A) signal and directional intercellular migration towards the ectoderm, the source of this signal. The PCM, they report, fails to spread during gast ...
Histamine in the development and maintenance of
... close relationship of photoreceptors with the underlying Retinal Pigment Epithelium, which is crucial for their survival. The OLM contains specialized adherens junctions between photoreceptors and adjacent Müller cells, which contain multiprotein complexes (containing ZO-1, -catenin, crumbs). Mutat ...
... close relationship of photoreceptors with the underlying Retinal Pigment Epithelium, which is crucial for their survival. The OLM contains specialized adherens junctions between photoreceptors and adjacent Müller cells, which contain multiprotein complexes (containing ZO-1, -catenin, crumbs). Mutat ...
Chapter 6: Cancer - Mendelian and Quantitative Genetics
... The Use and Misuse of Heritability Heritability does not tell us about individual differences Heritability is based on variances in populations, not individuals High heritability value for a trait does not automatically mean that most of the difference between two individuals is genetic. Copyr ...
... The Use and Misuse of Heritability Heritability does not tell us about individual differences Heritability is based on variances in populations, not individuals High heritability value for a trait does not automatically mean that most of the difference between two individuals is genetic. Copyr ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.