Expression of p53 Target Genes in the Early Phase of Long
... (Table 1). As described earlier [3, 69], our experimental protocol induces robust and enduring potentiation slightly reducing at 3 h after tetanization, which is characteristic of late-LTP produced in rat CA1 by repeated tetanization [70]. The application of vehicle (DMSO 0.1%) in perfusing milieu f ...
... (Table 1). As described earlier [3, 69], our experimental protocol induces robust and enduring potentiation slightly reducing at 3 h after tetanization, which is characteristic of late-LTP produced in rat CA1 by repeated tetanization [70]. The application of vehicle (DMSO 0.1%) in perfusing milieu f ...
Gregor Mendel
... the offspring will be white (this does NOT mean that they will or will not have white bunnies) – If they have LOTS of children, about 25% of them will be white Last slide ...
... the offspring will be white (this does NOT mean that they will or will not have white bunnies) – If they have LOTS of children, about 25% of them will be white Last slide ...
Ecological and molecular investigations of cyanotoxin production
... generally been attributed to cell lysis as a result of some detrimental growth factor, or culture age [19]. While the same data may also suggest an export of the toxin from the cell under certain conditions this has not been investigated. 5. Putative intracellular toxin functions Most putative intra ...
... generally been attributed to cell lysis as a result of some detrimental growth factor, or culture age [19]. While the same data may also suggest an export of the toxin from the cell under certain conditions this has not been investigated. 5. Putative intracellular toxin functions Most putative intra ...
PPT
... Cases of PWS & AS Two CF patients with short stature, inherited two identical copies of most or all of their maternal chr. 7. In both cases, the mother happened to be a carrier for CF Father-to-son transmission of hemophilia, affected boy inherited both X & Y from father Expression of X-linked in ho ...
... Cases of PWS & AS Two CF patients with short stature, inherited two identical copies of most or all of their maternal chr. 7. In both cases, the mother happened to be a carrier for CF Father-to-son transmission of hemophilia, affected boy inherited both X & Y from father Expression of X-linked in ho ...
-Chain Gene in Epididymis α Expression of the C4b
... C4BP␣, previously isolated by RT-PCR. These clones were divided into two groups according to the nucleotide sequences of their coding regions. Four of these clones encoded seven SCRs followed by the C-terminal region and were identified as the previously isolated sperm protein, AM67 (11). The other ...
... C4BP␣, previously isolated by RT-PCR. These clones were divided into two groups according to the nucleotide sequences of their coding regions. Four of these clones encoded seven SCRs followed by the C-terminal region and were identified as the previously isolated sperm protein, AM67 (11). The other ...
Gene quantification using real-time quantitative PCR
... and analysis of mRNA expression levels of genes important for the differentiation of cell types of an immune response. Detection of minimal residual disease Hematological malignancies characterized by specific genetic translocations can be used as tumor markers while monitoring the response to thera ...
... and analysis of mRNA expression levels of genes important for the differentiation of cell types of an immune response. Detection of minimal residual disease Hematological malignancies characterized by specific genetic translocations can be used as tumor markers while monitoring the response to thera ...
Supplementary Tutorial - WashU Epigenome Browser
... In this view, the chromosome ideogram below the heatmap is replaced by boxes. Each box represents one item (gene or genomic coordinate) submitted in the gene set, with the name inside of or adjacent to the box. The width of each box represents the relative length of the item. The “Zoom in” operation ...
... In this view, the chromosome ideogram below the heatmap is replaced by boxes. Each box represents one item (gene or genomic coordinate) submitted in the gene set, with the name inside of or adjacent to the box. The width of each box represents the relative length of the item. The “Zoom in” operation ...
There is more than one way to search the medical literature
... PDFs for PubMed citations by automatically searching Google. Be aware that incorrect links may sometimes appear for articles with short, common titles. Links to free full text articles indexed by PubMed are also displayed with some citations. PubNet http://pubnet.gersteinlab.org/ creates network gra ...
... PDFs for PubMed citations by automatically searching Google. Be aware that incorrect links may sometimes appear for articles with short, common titles. Links to free full text articles indexed by PubMed are also displayed with some citations. PubNet http://pubnet.gersteinlab.org/ creates network gra ...
Two-Component System of Mycobacterium Tuberculosis
... the histidine protein kinase (HK) PhoR, are involved in the induction of Pho-regulon genes including the phoPR operon and genes encoding the major vegetative alkaline phosphatases, phoA and phoB. The PhoP protein belongs to OmpR/PhoB subfamily, which is considered as the largest of the response regu ...
... the histidine protein kinase (HK) PhoR, are involved in the induction of Pho-regulon genes including the phoPR operon and genes encoding the major vegetative alkaline phosphatases, phoA and phoB. The PhoP protein belongs to OmpR/PhoB subfamily, which is considered as the largest of the response regu ...
1 mec-15 Encodes an F-box Protein Required for Touch
... channel subunit, is distributed as regular puncta throughout the TRN process (HUANG et al. 1995; ZHANG et al. 2004) that relies on intact microtubules (Bounoutas et al. submitted). This distribution was unchanged in mec-15 animals, indicating no obvious defects in axonal transport (Figure S2A). MEC ...
... channel subunit, is distributed as regular puncta throughout the TRN process (HUANG et al. 1995; ZHANG et al. 2004) that relies on intact microtubules (Bounoutas et al. submitted). This distribution was unchanged in mec-15 animals, indicating no obvious defects in axonal transport (Figure S2A). MEC ...
Genetic Coat Colour Determinism in Rabbits
... replaced by gg, as consequence the yellow color in the hair disappears and it becomes uniform all black. The genetic determinism of the black color may be A_B_C_D_gg,, but it also can be achi_B_C_D_gg. (Bud, 2005.). The Himalayan color is white, uniform on all the body except the extremities, respec ...
... replaced by gg, as consequence the yellow color in the hair disappears and it becomes uniform all black. The genetic determinism of the black color may be A_B_C_D_gg,, but it also can be achi_B_C_D_gg. (Bud, 2005.). The Himalayan color is white, uniform on all the body except the extremities, respec ...
A Tn 10-lacZ-kanR-URA3 Gene Fusion Transposon for Insertion Mutagenesis and Fusion Analysis of Yeast and Bacterial Genes.
... nicknamed mini-Tn 10-LUK, contains a lacZ gene without efficient transcription or translation start signals, an intact URA3 gene, and a RanR determinant. The lacZ gene can be activated by appropriate insertion of the element into an actively expressed gene. Other yeast genes can easily be substitute ...
... nicknamed mini-Tn 10-LUK, contains a lacZ gene without efficient transcription or translation start signals, an intact URA3 gene, and a RanR determinant. The lacZ gene can be activated by appropriate insertion of the element into an actively expressed gene. Other yeast genes can easily be substitute ...
Genetic predisposition to sarcoidosis: another brick in the wall EDITORIAL
... African–American sarcoidosis patients, and further studies in non-Europeans are likely to reveal intriguing new findings [25]. GWASs have not explained as much of the genetic components of many diseases, including sarcoidosis, as was anticipated. As the power of the GWAS approach increases with acce ...
... African–American sarcoidosis patients, and further studies in non-Europeans are likely to reveal intriguing new findings [25]. GWASs have not explained as much of the genetic components of many diseases, including sarcoidosis, as was anticipated. As the power of the GWAS approach increases with acce ...
Mating-Type Genes From the Homothallic Fungus Sordaria
... with the N. crassa A idiomorph. This similarity is markedly reduced further downstream from position 4860 of the S. macrospora sequence. The 3' sequence of SmtA3 reveals a significant homology with the N. crassa a idiomorph (Figure 3B). SmtA-3 is interrupted by one intron of 54 bp andencodes apolype ...
... with the N. crassa A idiomorph. This similarity is markedly reduced further downstream from position 4860 of the S. macrospora sequence. The 3' sequence of SmtA3 reveals a significant homology with the N. crassa a idiomorph (Figure 3B). SmtA-3 is interrupted by one intron of 54 bp andencodes apolype ...
Drugs and addiction: an introduction to epigenetics
... development of mental illness is gradual, and often shows a chronic relapsing course over a life-time [31]. The reversal of symptoms in response to treatment is slow, occurring over weeks to months, and chronic administration of psychiatric medications is often required for their full clinical effec ...
... development of mental illness is gradual, and often shows a chronic relapsing course over a life-time [31]. The reversal of symptoms in response to treatment is slow, occurring over weeks to months, and chronic administration of psychiatric medications is often required for their full clinical effec ...
Proceedings of the National Academy of Sciences
... development. The numerous functions include both structural and catalytic roles in a number of enzymes (1–3). However, in excess zinc is toxic, so both eukaryotes and prokaryotes have developed mechanisms to prevent overaccumulation of zinc, for example induction of metallothioneins that sequester z ...
... development. The numerous functions include both structural and catalytic roles in a number of enzymes (1–3). However, in excess zinc is toxic, so both eukaryotes and prokaryotes have developed mechanisms to prevent overaccumulation of zinc, for example induction of metallothioneins that sequester z ...
Analysis of the mitochondrial COI gene and its
... by the DNA Barcoding Consortium (Hebert et al., 2003; Stoeckle, 2003). This region is comprised of approximately 640 nucleotides (Folmer et al., 1994) and has been used as a unique identification code for many species. Additionally, this region is used to facilitate the correct identification of spe ...
... by the DNA Barcoding Consortium (Hebert et al., 2003; Stoeckle, 2003). This region is comprised of approximately 640 nucleotides (Folmer et al., 1994) and has been used as a unique identification code for many species. Additionally, this region is used to facilitate the correct identification of spe ...
Pro-Apoptotic Role of the Human YPEL5 Gene Identified by
... regulated by the tumor suppressor protein p53, with lower expression in several human tumors [5-7]. These previous observations raised the possibility that human YPEL family proteins play an important role in the regulation of cell division and/or apoptosis; however, this prediction remains to be el ...
... regulated by the tumor suppressor protein p53, with lower expression in several human tumors [5-7]. These previous observations raised the possibility that human YPEL family proteins play an important role in the regulation of cell division and/or apoptosis; however, this prediction remains to be el ...
PAG 2012 - Illumina
... Applied Genomics for Genetic Improvement: Paving the Way for Biological Discovery Tad S. Sonstegard, Ph.D. Research Geneticist USDA, ARS Beltsville ...
... Applied Genomics for Genetic Improvement: Paving the Way for Biological Discovery Tad S. Sonstegard, Ph.D. Research Geneticist USDA, ARS Beltsville ...
Guidance on the Use of Biochemical and Molecular Markers
... descriptions), can be set with a suitable margin of safety, because those varieties which are eliminated, will not be included in the growing trial. This threshold, with a safety margin, is termed the “Distinctness plus” threshold which means that the distances between a candidate variety and “disti ...
... descriptions), can be set with a suitable margin of safety, because those varieties which are eliminated, will not be included in the growing trial. This threshold, with a safety margin, is termed the “Distinctness plus” threshold which means that the distances between a candidate variety and “disti ...
Interspecies Bacterial Conjugation by Plasmids from Marine
... Horizontal gene exchange is of importance in the adaptation and evolution of bacteria (reviewed in Syvanen 1994). When bacterial DNA sequences and their GC contents and/or codon usage have been analyzed, many cases of possible horizontal gene transfer events have been revealed. For example, as much ...
... Horizontal gene exchange is of importance in the adaptation and evolution of bacteria (reviewed in Syvanen 1994). When bacterial DNA sequences and their GC contents and/or codon usage have been analyzed, many cases of possible horizontal gene transfer events have been revealed. For example, as much ...
7. Rh Blood Group System - Austin Community College
... These two theories are the basis for the two notations currently in use for the Rh system. The table below compares Fisher-Race and Wiener notations. Immunohematologists use combinations of both systems when recording the most probable genotype. You must memorize and be able to convert from the Fish ...
... These two theories are the basis for the two notations currently in use for the Rh system. The table below compares Fisher-Race and Wiener notations. Immunohematologists use combinations of both systems when recording the most probable genotype. You must memorize and be able to convert from the Fish ...
Abnormalities of epidermal differentiation associated with
... per cell (mice 27-5 and 48-16), at approximately 10 copies (mice 48-10 and 48-11) and at 15 to 20 copies (mouse 27-7). Each of these founder animals was mated to provide transgenic progeny for further analysis. To look for papillomavirus gene expression in the skin of transgenic mice descended from ...
... per cell (mice 27-5 and 48-16), at approximately 10 copies (mice 48-10 and 48-11) and at 15 to 20 copies (mouse 27-7). Each of these founder animals was mated to provide transgenic progeny for further analysis. To look for papillomavirus gene expression in the skin of transgenic mice descended from ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.