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Category 2000
Category 2000

... Peroxisome proliferator-activated receptor coactivator 1 (PPARGC1A) is a versatile coactivator with many functions, but is primarily involved in fat and energy metabolism. Therefore, it is a very interesting candidate gene for meat quality, which is one of the most important criteria in pig selectio ...
BMC Genomics 10
BMC Genomics 10

... In addition, seven small linkage groups with an average of three SNPs in each were produced. Comparative mapping indicated that the largest of these, which comprised five SNPs located in the genes USP24, EIF2B3, OMA1, CPT2, and GPX7, was associated with the distal part of porcine chromosome 6 (Sus s ...
209 Original Scientific Article THE INFLUENCE OF
209 Original Scientific Article THE INFLUENCE OF

... Figure 4. Progress in relative abundance of DNMT1 (A, B) and DNMT3a (C, D) transcripts in intergeneric embryos (porcine fibroblast in bovine oocyte) compared with bovine parthenogenetic embryos. mRNA from pools (triplicates) of 10 embryos each at the 2-cell, 4-cell, 8-cell and 16-cell stages were re ...
PowerPoint Presentation - The pace of Dr. Taub`s lectures have been
PowerPoint Presentation - The pace of Dr. Taub`s lectures have been

... • D: Recombination takes place at a high rate between two alleles ...
PP - My Teacher Site
PP - My Teacher Site

... 2) An organism with the genotype BbDD is mated to one with the genotype BBDd. Assuming independent assortment of these 2 genes, write the genotypes of all possible offspring from this cross and use the rules of probability to calculate the chance of each genotype occurring. ...
Drosophila melanogaster Preferential Segregation of the Fourth
Drosophila melanogaster Preferential Segregation of the Fourth

... 0.8; eyD to gvl with a value of 51.9 1.3. This is not an effect of the Y-chromosome, since females with attached X's and a Y give the same results as those with separate X's and no Y. A few similar duplicating chromosomes have been tested, in which the spindle-fibre attachment was derived from an X; ...
Drosophila Infections in for Resistance to Gram
Drosophila Infections in for Resistance to Gram

... main anti-Gram-positive peptide gene, Defensin, reaches similar low levels in all tested mutant backgrounds after immunization with E. faecalis. We conclude that Defensin is not necessary for resistance against this Gram-positive bacterium since key mutants do not express Defensin at high levels, ye ...
Simple Sequence Repeats as Advantageous Mutators
Simple Sequence Repeats as Advantageous Mutators

... effects of SSR alleles remains challenging, however, even when they appear within genes whose functions have been established, such as fruit fly period, vole avpr1a, dog Alx-4 and Runx-2, and yeast RAS2. Ideally, an incremental effect of repeat number should be demonstrated over a range of quantitat ...
Rice Bioinformatics. Analysis of Rice Sequence Data and
Rice Bioinformatics. Analysis of Rice Sequence Data and

... that represent diverse physiological and developmental programs, complete genomic sequencing is unlikely to be completed in the foreseeable future. Thus, sequencing of ESTs remains the primary tool for genomic exploration and for functional genomics analyses. The value of EST resources can be greatl ...
doyne lecture rhodopsin and autosomal dominant retinitis
doyne lecture rhodopsin and autosomal dominant retinitis

... important functions in that tissue. Patients with the disease ...
Chapter 20
Chapter 20

... • Reproduction in the bacterial cell results in cloning of the plasmid including the foreign DNA • This results in the production of multiple copies of a single gene Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings ...
RNA and Protein Synthesis
RNA and Protein Synthesis

... they understood right away how DNA could be copied. All a cell had to do was to separate the two strands and then use base pairing to make a new complementary strand for each. But the structure of DNA by itself did not explain how a gene actually works. That question required a great deal more resea ...
Chapter 14 Study Guide Mendel and the Gene Idea A.P. Biology Ms
Chapter 14 Study Guide Mendel and the Gene Idea A.P. Biology Ms

... and IB alleles are said to be co-dominant. 22. Define and give examples of pleiotrophy and epistasis. 23. Describe a simple model for polygenic inheritance and explain why most polygenic characters are described in quantitative. 24. Describe how environmental conditions can influence the phenotypic ...
25/05
25/05

... 4. Now do ex. 9.2 by adding another subroutine that takes: (1) a protein accession, (2) a protein length and (3) a reference to such a hash, and returns 0 if the accession is not found, 1 if the length is identical to the one in the hash, and 2 otherwise. 5.* Now add a third input file and check if ...
Linkage and Gene Mapping
Linkage and Gene Mapping

... Draw a Punnett square which represents this cross … ...
Zygotic genes that mediate torso receptor tyrosine kinase
Zygotic genes that mediate torso receptor tyrosine kinase

... Previous studies of the embryonic termini have emphasized the role of the terminal genes in distinguishing terminal cell fates from central cell fates along the antero-posterior axis of the embryo. The development of the termini, however, entails a complex series of patterning and morphogenetic even ...
The viriosphere, diversity, and genetic exchange within phage
The viriosphere, diversity, and genetic exchange within phage

... eukaryotic algae [31], and also for podoviruses, where in one case indistinguishable podovirus-like sequences occurred in samples collected from freshwater as well as from marine sediment and water samples [32]. Such results are significant because they imply that phage genes are moving among viru ...
POTE Paralogs Are Induced and Differentially Expressed in Many
POTE Paralogs Are Induced and Differentially Expressed in Many

... many cancers (10). Cancer-testis antigens are often expressed at higher levels in testis and placenta, which are known to express only low amounts of MHC class I molecules. Thus, expression of cancer-testis antigens in these normal tissues should not lead to Tcell activation and this makes these ant ...
Hierarchical Text Categorization and Its Evaluation
Hierarchical Text Categorization and Its Evaluation

... • not a learning technique on its own, but a method in which a family of “weakly” learning agents (simple learners) is used for learning • based on the fact that multiple classifiers that disagree with one another can be together more accurate than its component classifiers • if there are L classifi ...
Different strategies of osmoadaptation in the closely
Different strategies of osmoadaptation in the closely

... E. coli, we deleted the gene otsB, which encodes trehalose-6phosphate phosphatase. The DNA regions upstream and downstream of otsB were joined by applying the SOE-PCR technique. The resulting DotsB fragment was cloned into the temperature-sensitive plasmid pMAK705, which facilitated the selection fo ...
lecture - Berkeley MCB
lecture - Berkeley MCB

... regulation, is really like • Trans-acting factors do not distribute in the nucleus based on the primary sequence of the genome: some factors fail to bind most genes that have sequences waiting for them, and other factors bind a large number of genes that do NOT have sequences for them • Even when a ...
Multiple testing
Multiple testing

... The multiple comparison correction methods can provide adjusted p-values, though in general calculation of the adjusted p-value is more complicated than is the case for Bonferroni. Holm’s test For the Bonferroni correction, we apply the same critical value (alpha/k) to all the hypotheses simultaneou ...
Sugars, signalling, and plant development
Sugars, signalling, and plant development

... 3368 | Eveland and Jackson Rolland et al., 2002, 2006; Gibson, 2005). For example, glucose insensitive (gin) mutants fail to undergo growth arrest in the presence of inhibitory levels of glc, exhibiting normal hypocotyl elongation, cotyledon greening, and expansion. Independent screens for other su ...
Teacher Guide: Gene Expression. By Ann Brokaw.
Teacher Guide: Gene Expression. By Ann Brokaw.

... include up-to-date research, prompt students to process material, help reinforce textbook material, and stimulate discussions and explorations of current biological topics. For these reasons, I routinely use HHMI’s BioInteractive website and Holiday Lectures on Science DVDs in my classroom to highli ...
word
word

... interested in cell growth and proliferation patterns during seed development and how the different parts that comprise a seed coordinate their development. Research from many groups has shown that epigenetic regulation plays an import role during seed development. Among other epigenetic mechanisms i ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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