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Lung cancer: an ever increasing store of in-depth basic
Lung cancer: an ever increasing store of in-depth basic

... aberrations in lung cancer include the Rb gene at 13q14 and the p16 gene at 9p21. The Rb gene was initially cloned as a prototype tumor suppressor gene responsible for a rare childhood tumor, retinoblastoma, while among human adult cancers SCLC is a prominent and distinct example of a carcinoma carr ...
Recombinant DNA II
Recombinant DNA II

The B-box zinc finger family transcription factor, AtDBF1, is a positive
The B-box zinc finger family transcription factor, AtDBF1, is a positive

... Functional analysis of a putative novel transcription factor Arabidopsis B-box zinc finger family transcription factor protein designated AtDBF1, which contains predicted DNAbinding domain, was performed. The precise roles of the B-box zinc finger family transcription factors in plant stress are poo ...
DNA Fingerprinting Lab
DNA Fingerprinting Lab

... One test used in forensic labs is DNA fingerprint. It is also called a DNA profile. Analysts use the DNA profile from potential suspects and compare it against DNA found at a crime scene. There’s DNA profiling for paternity tests. These days you can send a sample of DNA and find out your ancestry to ...
LP7 - Inheritance and Genetic Diseases
LP7 - Inheritance and Genetic Diseases

... also known as von Recklinghausen disease) is a genetically-inherited disorder in which the nerve tissue grows tumors (neurofibromas) that may be benign and may cause serious damage by compressing nerves and other tissues. Neurofibromatosis is an autosomal dominant disorder, which means only one copy ...
When epigenetics meets alternative splicing: the roles of DNA
When epigenetics meets alternative splicing: the roles of DNA

... KEYWORDS: DNA methylation n GC content n splicing ...
chapter 14
chapter 14

Non-allelic Genes Interactions
Non-allelic Genes Interactions

... plant with white kernels (genotype = aabb) and the resulting F1 plants are selfed, a modification of the dihybrid 9:3:3:1 ratio will be produced. The following table provides a biochemical explanation for the 15:1 ratio. ...
Microarray data analysis
Microarray data analysis

... data sets. In one common scenario, samples are labeled with Cy3 (green dye) or Cy5 (red dye) and hybridized to DNA elements on a microrarray. After washing, probes are excited with a laser and detected with a scanning confocal microscope. ...
Meyer Prometheus Presentation - American Intellectual Property
Meyer Prometheus Presentation - American Intellectual Property

... These materials are public information and have been prepared solely for educational and entertainment purposes to contribute to the understanding of U.S. intellectual property law and practice. These materials reflect only the personal views of the speaker and are not individualized legal advice. I ...
Whose got Genes? - Miss White`s Science Class
Whose got Genes? - Miss White`s Science Class

... What is HETEROZYGOUS? When offspring inherit one dominant gene and one recessive gene, they are said to be heterozygous Since the dominant gene will always be expressed, they are said to be heterozygous dominant When offspring are heterozygous, they are said to be a CARRIER of the recessive trait ...
Chapter 12 Study Guide 12.1 Identifying the Substance of Genes
Chapter 12 Study Guide 12.1 Identifying the Substance of Genes

... Bacterial Transformation In 1928, Frederick Griffith found that some chemical factor from heat-killed bacteria of one strain could change the inherited characteristics of another strain. He called the process transformation because one type of bacteria (a harmless form) had been changed permanently ...
HumanGeneticDisorders
HumanGeneticDisorders

... translocations ...
Patterns of Inheritance Worksheet #5
Patterns of Inheritance Worksheet #5

... 4. Red/Green color blindness is also an X-linked recessive trait. A color-blind woman marries a man with normal color vision. What are the chances that their children will be color-blind? Express your answer as a percentage. Show all of your work. (2 pts) ...
Deteksi Mutasi Gen Gyrase A Porphyromonas Gingivalis Resisten
Deteksi Mutasi Gen Gyrase A Porphyromonas Gingivalis Resisten

... ABSTRACT One of resistance mechanisms to ciprofloxacin shown by bacterium Porphyromonas gingivalis isolated from periodontitis patients is mutations of genes through changes in DNA topoisomerase. Ciprofloxacin is an effective antimicrobial for Gram-negative bacteria effectively used for clinical inf ...
Q1. Cystic fibrosis is an inherited disorder. Mr and Mrs Brown do not
Q1. Cystic fibrosis is an inherited disorder. Mr and Mrs Brown do not

... of producing drip dry shirts made from natural fibres. Other cotton plants are being genetically engineered to produce their own insecticides. When they have perfected these new types of cotton plants, the scientists will use cloning techniques to produce large numbers of them. ...
Senate inquiry into gene patents - Clinical Oncology Society of
Senate inquiry into gene patents - Clinical Oncology Society of

... ovarian cancer testing and, as a precedent, for the future of freely available genetic testing (and related issues explored in this submission) in Australia. On 20 November 2008, Genetic Technologies withdrew its enforcement notice6 and stated a return to its position of 2003 – when it publicly asse ...
chromosome 17
chromosome 17

... • Increases or decreases in size do not correlate with number of genes • Polyploidy in plants does not by itself explain differences in genome size • A greater amount of DNA is explained by the presence of introns and nonprotein-coding sequences than gene duplicates ...
Coat Color Genetics - Hocking County 4
Coat Color Genetics - Hocking County 4

... • Genetic inheritance determines a Paint’s coat pattern. What is genetic inheritance? It is the genes (genetic codes) parents pass on to their offspring. • Why is this important? It is important for Paint Horse breeders to understand genetic inheritance so they can breed for certain coat patterns, p ...
8/22/13 Comp 555 Fall 2013 1 - UNC Computational Systems Biology
8/22/13 Comp 555 Fall 2013 1 - UNC Computational Systems Biology

... showed that genes were located on chromosomes. Experimenting with Drosophila (fruit flies) they found sex chromosomes, sex-linked traits, and crossing-over. They were able to associate mutations to specific chromosomal regions, thus mapping gene locations. •  By the 1930's biochemists knew that the ...
Regulation
Regulation

... – RNA-poly binds freely to promoter – Constitutive genes— Enzymes always needed (e.g., glycolysis) • Negative gene regulation – Repressor protein binds operator → Block RNA polymerase → Inhibits gene expression → Decreases synthesis of enzymes • Positive gene regulation – Activator protein binds sep ...
Sex Linked Traits
Sex Linked Traits

... • A carrier is a person that has the trait on only one chromosome and does not express the trait. Carriers of sex linked traits are always women. (C= normal, c= colorblind) Ex. Color blind carrier XC Xc ...
Mendelian Inheritance
Mendelian Inheritance

... having sickle cell disease? ...
ATM gene - MyriadPro
ATM gene - MyriadPro

... lifetime risk for women in the general population of the United States. The increase in risk may be especially significant at young ages. ATM mutations have been found in families with 2 or more cases of pancreatic cancer in close relatives, indicating that there is an increased risk for pancreatic ...
Whole genome sequencing - Center for Biological Sequence Analysis
Whole genome sequencing - Center for Biological Sequence Analysis

... • Learn how to prepare raw data from the sequencer for further bioinformatic analysis. • Be able to use tools for In silico detection of plasmid, resistance and virulence genes. • Be able to perform global and local WGS analysis to determine clonal relationship of bacteria (SNP, ND, MLST). ...
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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications. There is now considerable evidence that nutritional imbalances during gestation and lactation are linked to non-communicable diseases, such as obesity, cardiovascular disease, diabetes, hypertension, and cancer. If metabolic disturbances occur during critical time windows of development, the resulting epigenetic alterations can lead to permanent changes in tissue and organ structure or function and predispose individuals to disease.
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