Whole genome sequencing - Center for Biological Sequence Analysis
... • Learn how to prepare raw data from the sequencer for further bioinformatic analysis. • Be able to use tools for In silico detection of plasmid, resistance and virulence genes. • Be able to perform global and local WGS analysis to determine clonal relationship of bacteria (SNP, ND, MLST). ...
... • Learn how to prepare raw data from the sequencer for further bioinformatic analysis. • Be able to use tools for In silico detection of plasmid, resistance and virulence genes. • Be able to perform global and local WGS analysis to determine clonal relationship of bacteria (SNP, ND, MLST). ...
Supplementary Information
... The crtP and crtQ genes were newly acquired in cyanobacteria and subsequently maintained in photosynthetic eukaryotes, and phylogenetic analysis showed that these proteins may have evolved originally from bacterial desaturases involved in the formation of aromatic end groups [1]. Both the P. tricorn ...
... The crtP and crtQ genes were newly acquired in cyanobacteria and subsequently maintained in photosynthetic eukaryotes, and phylogenetic analysis showed that these proteins may have evolved originally from bacterial desaturases involved in the formation of aromatic end groups [1]. Both the P. tricorn ...
Mutational analysis of the connexin 36 gene (CX36)
... The murine connexin 36 gene (Cx36) encodes a gap-junction channel protein which is preferentially expressed in brain and retina. The human orthologue CX36 is located on chromosome 15q14, a region recently shown to contain a susceptibility gene for hereditary catatonic schizophrenia. Therefore, CX36 ...
... The murine connexin 36 gene (Cx36) encodes a gap-junction channel protein which is preferentially expressed in brain and retina. The human orthologue CX36 is located on chromosome 15q14, a region recently shown to contain a susceptibility gene for hereditary catatonic schizophrenia. Therefore, CX36 ...
Horizontal Gene Transfer among Bacteria and its Role in
... Upon genetic experimentation using several bacterial strains and their phages, a phenomenon called host-controlled modification was encountered by a few independent scientists. In the 1960’s we succeeded to unravel its molecular mechanisms [10]. In brief, many strains of bacteria possess one or even ...
... Upon genetic experimentation using several bacterial strains and their phages, a phenomenon called host-controlled modification was encountered by a few independent scientists. In the 1960’s we succeeded to unravel its molecular mechanisms [10]. In brief, many strains of bacteria possess one or even ...
Crossing Over during Meiosis
... pairs will lead (eventually) to gene maps of each chromosome. • Pair-wise and three-locus linkage associations can be formed. • The frequencies of recombination can also be used to estimate the physical distance between loci along a chromosome. • The values for recombination frequency can be conside ...
... pairs will lead (eventually) to gene maps of each chromosome. • Pair-wise and three-locus linkage associations can be formed. • The frequencies of recombination can also be used to estimate the physical distance between loci along a chromosome. • The values for recombination frequency can be conside ...
Lecture_note_463BI
... found on most if not all human chromosomes. McBride et al. (1989) described short, 8-12 nucleotide, direct terminal repeats flanking many of the dispersed tRNA genes. This finding, combined with the dispersion of tRNA genes, suggests that many of these genes may have arisen by an RNA-mediated retrop ...
... found on most if not all human chromosomes. McBride et al. (1989) described short, 8-12 nucleotide, direct terminal repeats flanking many of the dispersed tRNA genes. This finding, combined with the dispersion of tRNA genes, suggests that many of these genes may have arisen by an RNA-mediated retrop ...
BPS 555
... Heterochromatin is Highly Organized and Usually Resistant to Gene Expression Two types of chromatin exist in interphase nuclei of many higher eucaryotic cells: Euchromatin is less condensed and associated with genes that are expressed. Heterochromatin is highly condensed and usually does not contai ...
... Heterochromatin is Highly Organized and Usually Resistant to Gene Expression Two types of chromatin exist in interphase nuclei of many higher eucaryotic cells: Euchromatin is less condensed and associated with genes that are expressed. Heterochromatin is highly condensed and usually does not contai ...
Basics for Bioinformatics
... organisms appeared in the last few days: first land plants and first land animals all appeared on day 28, mammals began to exist on day 29, and birds and flowering plants came into being on the last day. Modern humans, which are named homo sapiens in biology, appeared in the last 10 min of the last ...
... organisms appeared in the last few days: first land plants and first land animals all appeared on day 28, mammals began to exist on day 29, and birds and flowering plants came into being on the last day. Modern humans, which are named homo sapiens in biology, appeared in the last 10 min of the last ...
DNA upgrade supplement WITH PICS
... units. Unfortunately, knowing the components of DNA did not solve the mystery of whether the DNA or protein component of chromosomes functioned as genes. The next steps in identifying the hereditary molecule involved determining exactly which component carried genetic information. Scene 16: In 1928, ...
... units. Unfortunately, knowing the components of DNA did not solve the mystery of whether the DNA or protein component of chromosomes functioned as genes. The next steps in identifying the hereditary molecule involved determining exactly which component carried genetic information. Scene 16: In 1928, ...
Behavior Genetics and Evolutionary Psychology
... weight and height are heritable and yet nutritional influences have made westerners heavier and taller than their ancestors a century ago. ...
... weight and height are heritable and yet nutritional influences have made westerners heavier and taller than their ancestors a century ago. ...
Comparison of Discrimination Methods for the
... In the main comparison, NN and DLDA had the smallest error rates, while FLDA had the highest error rates Aggregation improved the performance of CART classifiers, the largest gains being with boosting and bagging with CPD For the lymphoma and leukemia datasets, increasing the number of variables to ...
... In the main comparison, NN and DLDA had the smallest error rates, while FLDA had the highest error rates Aggregation improved the performance of CART classifiers, the largest gains being with boosting and bagging with CPD For the lymphoma and leukemia datasets, increasing the number of variables to ...
Chapter 12 Human Genetics
... of the nervous system with an onset from age 40 onward, which time the gene has usually been passed on to offspring • Achondroplasia (dwarfism) Benign abnormality that does not affect the person reproductively ...
... of the nervous system with an onset from age 40 onward, which time the gene has usually been passed on to offspring • Achondroplasia (dwarfism) Benign abnormality that does not affect the person reproductively ...
掌握相关的疾病基因组学研究技术新进展。
... • Autosomal dominant polycystic kidney disease (ADPKD) • The most common form of PKD with an estimated incidence of approximately 1/400 to 1/1 000 individuals worldwide. It roughly accounts for 10% of patients with chronic ...
... • Autosomal dominant polycystic kidney disease (ADPKD) • The most common form of PKD with an estimated incidence of approximately 1/400 to 1/1 000 individuals worldwide. It roughly accounts for 10% of patients with chronic ...
Lab 7 - Bacterial Transformation
... be beneficial to bacterial survival. In nature, bacteria can transfer plasmids back and forth, which creates the opportunity for them to share these beneficial genes. (Note that the bacteria don’t know that they are picking up beneficial genes.) This natural mechanism allows bacteria to adapt to new ...
... be beneficial to bacterial survival. In nature, bacteria can transfer plasmids back and forth, which creates the opportunity for them to share these beneficial genes. (Note that the bacteria don’t know that they are picking up beneficial genes.) This natural mechanism allows bacteria to adapt to new ...
1. What are the 3 parts of DNA nucleotide?
... 7. What does complementary mean? They are not identical but fit with one another. A is complementary to T, C is complementary to G. 8. How is DNA assembled? What does antiparallel mean? DNA is a long chain of nucleotides linked together. The strands run antiparallel, in opposite directions. 9. Circl ...
... 7. What does complementary mean? They are not identical but fit with one another. A is complementary to T, C is complementary to G. 8. How is DNA assembled? What does antiparallel mean? DNA is a long chain of nucleotides linked together. The strands run antiparallel, in opposite directions. 9. Circl ...
1. Single gene traits
... genotype – the genetic code of an organism; which alleles are present dominant – the allele that determines the phenotype of a heterozygote and masks the expression of the recessive allele recessive – the allele that is masked by the presence of a dominant allele in a heterozygote. The recessive phe ...
... genotype – the genetic code of an organism; which alleles are present dominant – the allele that determines the phenotype of a heterozygote and masks the expression of the recessive allele recessive – the allele that is masked by the presence of a dominant allele in a heterozygote. The recessive phe ...
Racial Mixing - An Overview - Mendelan Laws of InheritancePart 4
... In a practical example, if a pure Black breeds with a pure White, the offspring might emerges with a new "mutant" recessive allele (a), being heterozygous (i.e., along with a more dominant one, represented by "Ab"). If that mixed race individual then marries back into the White genotype pool, statis ...
... In a practical example, if a pure Black breeds with a pure White, the offspring might emerges with a new "mutant" recessive allele (a), being heterozygous (i.e., along with a more dominant one, represented by "Ab"). If that mixed race individual then marries back into the White genotype pool, statis ...
Gene Interactions – Extensions to Mendelian Genetics
... • A pair of genes can often work together to create a specific phenotype. We call this complementary interaction. • With this type of interaction we see 2 different phenotypes instead of the 4 seen in 2 genes 1 phenotype • Two or more genotypic classes may display an identical phenotype. – Example: ...
... • A pair of genes can often work together to create a specific phenotype. We call this complementary interaction. • With this type of interaction we see 2 different phenotypes instead of the 4 seen in 2 genes 1 phenotype • Two or more genotypic classes may display an identical phenotype. – Example: ...
ADDRESSING THE BITTER TRAIT IN CHICORY “PUNTARELLE
... vegetable; Molfettese and Galatina are Apulian landraces consumed for their tender stems (turions or "puntarelle"). Bitterness is an important organoleptic trait, which directs both consumer and breeding choices and is linked to the content of sesquiterpene lactones (STLs). Major STLs (lactucin, 8-d ...
... vegetable; Molfettese and Galatina are Apulian landraces consumed for their tender stems (turions or "puntarelle"). Bitterness is an important organoleptic trait, which directs both consumer and breeding choices and is linked to the content of sesquiterpene lactones (STLs). Major STLs (lactucin, 8-d ...
Recitation Section 11 Answer Key Bacterial Genetics
... i.e. the strains in the experiment have to complement each other. 3. A complementation test determines whether a. two pieces of DNA in the two strains interact with each other b. two pieces of DNA in the two strains are identical to each other c. products of expression of the gene(s) of interest i ...
... i.e. the strains in the experiment have to complement each other. 3. A complementation test determines whether a. two pieces of DNA in the two strains interact with each other b. two pieces of DNA in the two strains are identical to each other c. products of expression of the gene(s) of interest i ...
The origin of life molecules Nucleotide（核苷酸）
... as coenzymes and cofactors, or to another protein or other macromolecule (DNA, RNA, etc.), or to complex macromolecular assemblies. • Peptides are distinguished from proteins on the basis of size, and as a benchmark can be understood to contain approximately 50 amino acids or less. ...
... as coenzymes and cofactors, or to another protein or other macromolecule (DNA, RNA, etc.), or to complex macromolecular assemblies. • Peptides are distinguished from proteins on the basis of size, and as a benchmark can be understood to contain approximately 50 amino acids or less. ...
Microarray poster-final - London Regional Genomics Centre
... disequilibrium tests can analyze potential association between phenotypes and marker loci when pedigree information is not available. 3) Transmission disequilibrium tests can provide high-resolution localization of potential markers when genotypes of many affected individuals and their parents are m ...
... disequilibrium tests can analyze potential association between phenotypes and marker loci when pedigree information is not available. 3) Transmission disequilibrium tests can provide high-resolution localization of potential markers when genotypes of many affected individuals and their parents are m ...
Spr01Exam II Answer Key
... Hot dog sales around the country have taken a serious plunge and the high profile case has both scientists and the public worried about where or how this E.coli strain became pathogenic. Although the colonies look very different from E.coli, the initial genotyping hasn’t shown any genetic difference ...
... Hot dog sales around the country have taken a serious plunge and the high profile case has both scientists and the public worried about where or how this E.coli strain became pathogenic. Although the colonies look very different from E.coli, the initial genotyping hasn’t shown any genetic difference ...
Unit 4 – Genetics Heredity Test Study Guide Chapter 13
... c) What are the chances that Jim and Kay would have another child that has Cowden’s Syndrome? 16. What are the chances that a mating between two carriers will produce an offspring with a recessively inherited disease? 17. What is the probability that a phenotypically normal child produced by a matin ...
... c) What are the chances that Jim and Kay would have another child that has Cowden’s Syndrome? 16. What are the chances that a mating between two carriers will produce an offspring with a recessively inherited disease? 17. What is the probability that a phenotypically normal child produced by a matin ...