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Foundations of Biology - Geoscience Research Institute
Foundations of Biology - Geoscience Research Institute

... mtDNA is much smaller than bacterial chromosomes. Mitochondrial DNA may be linear; examples include: Plasmodium, C. reinhardtii, Ochromonas, Tetrahymena, Jakoba (Gray et al., 1999). Mitochondrial genes may have introns which eubacterial genes typically lack (these introns are different from nuclear ...
WP4 - Tomsett
WP4 - Tomsett

... Lane 2 = gcs3 plasmid control Lane 3 = gcs3 transformant Lane 4 = gcs4 plasmid control Lane 5 = gcs4 transformant Lane 6 = gsat1 plasmid control ...
AP Biology Notes Outline Chapter 27 Bacteria and Archaea Concept
AP Biology Notes Outline Chapter 27 Bacteria and Archaea Concept

... Concept 27.5: Prokaryotes and the Biosphere Prokaryotes play crucial roles in the biosphere:  Many prokaryotes are decomposers, breaking down dead organic matter.  Many prokaryotes are symbiotic, forming crucial relationships with other species.  Some prokaryotes are pathogenic and cause illness ...
Effects of rare codon clusters on high-level expression
Effects of rare codon clusters on high-level expression

... E. coli, and indeed all cells, uses a specific subset o f the 61 available amino acid codons for the production o f most m R N A molecules [1,2]. So-called major codons are those that occur in highly expressed genes, whereas the minor or rare codons tend to be in genes expressed at a low level. This ...
Nonrandom cell-cycle timing of a somatic chromosomal
Nonrandom cell-cycle timing of a somatic chromosomal

... The cell-cycle timing of somatic chromosomal translocations in cancer remains poorly understood but may be relevant to their etiology and the mechanism of their formation. Alveolar soft-part sarcoma (ASPS) is a rare malignant soft-tissue tumor of uncertain lineage that provides an opportunity to add ...
Document
Document

... • Mendel reasoned that only the purple flower factor was affecting flower color in the F1 hybrids • Mendel called the purple flower color a dominant trait and white flower color a recessive trait • Mendel observed the same pattern of inheritance in six other pea plant characters, each represented b ...
powerpoint - McGill University
powerpoint - McGill University

... which had been under BZ or ML treatment “An allele frequency of ≥65% was detected in one of the two flocks in 13 (29%) of the 45 farms examined. On many farms (24, 25, 33, 36, 37, 39, 42, 43 and 44) the allele frequency was similar in both the BZ and ML treated flocks” ...
Activity Name - Science4Inquiry.com
Activity Name - Science4Inquiry.com

... page 10 ...
RNA-based regulation of genes of tryptophan synthesis
RNA-based regulation of genes of tryptophan synthesis

... capability was dispensed with when the trp aporepressor, while charged and uncharged tRNATrp determine whether transcription organisms evolved that were capable of will or will not be terminated in the operon’s leader region. A poorly expressed internal provides transcripts producing low levels of t ...
Assessing the Homogeneity of Plasmid DNA: An Important
Assessing the Homogeneity of Plasmid DNA: An Important

... used to assess the homogeneity of plasmid DNA, but this approach has some major disadvantages. The AGE method is manual, only semi-quantitative, and the assignment of bands to plasmid structures is difficult since the electrophoretic mobility of plasmids of different shapes changes with the electrop ...
ABCA3 Gene Mutations in Newborns with Fatal
ABCA3 Gene Mutations in Newborns with Fatal

... The genes for ATP-binding cassette (ABC) transporters encode membrane proteins involved in the transport of compounds across biologic membranes, and 14 ABC genes have been associated with distinct genetic diseases in humans.3 Several ABC transporters are involved in the transport of phospholipids an ...
The uSe of mAnnoSe SeleCTion SySTem foR gene
The uSe of mAnnoSe SeleCTion SySTem foR gene

Molecular regulators of phosphate homeostasis in plants
Molecular regulators of phosphate homeostasis in plants

... Molecular regulators of Pi homeostasis | 1431 Mutants isolated by alteration of Pi concentration The most direct approach used to isolate mutants involved in the maintenance of Pi homeostasis is the measurement of cellular Pi concentrations. Analysis of leaf Pi concentrations revealed mutants with ...
25/05
25/05

... Subroutines A subroutine is a user-defined function. Subroutine definition: sub SUB_NAME { STATEMENT1; STATEMENT2; ...
Hardy-Weinberg Equilibrium – The Basic Model of Population
Hardy-Weinberg Equilibrium – The Basic Model of Population

... Gene: A region of the genome, a sequence of DNA (or RNA), that is the unit of inheritance, the product of which contributes to phenotype. Allele: Variant forms of a gene (e.g. alleles for wet or dry ...
Evolution of a pseudo-control region in the mitochondrial genome of
Evolution of a pseudo-control region in the mitochondrial genome of

... approach a 2.5 kb PCR fragment comprising the section between ND6 and 12s genes was isolated from Buteo buteo hureo,cloned and sequenced. The gene order corresponds to the novel arrangement described for Folco peregrinrrs by Mindell et al. (1998). The fragment includes a non coding section between t ...
A Maize Glutaredoxin Gene, Abphyl2, Regulates
A Maize Glutaredoxin Gene, Abphyl2, Regulates

... bonds in the presence of NADPH and glutathione reductase (Fernandes and Holmgren, 2004). Based on the conserved active site sequences, plant GRXs are divided into CPYC-, CGFC-, and CC-type classes. Plant GRX genes function in stress and pathogen responses (Ndamukong et al., 2007; Cheng, 2008; Guo et ...
Case-Parent Triads
Case-Parent Triads

... that the relative risk is greater or less than multiplicative when the variant allele is carried by both mother and fetus. Using the model with both C (case) and M (mother), one can test for significant loss of fit when either one is omitted, using the likelihood ratio test. This allows a test of wh ...
First genomic insights into members of a candidate bacterial
First genomic insights into members of a candidate bacterial

... issues have emerged such as the sudden washout of granular sludge biomass due to overgrowth of filamentous bacteria (bulking), which can lead to complete loss of performance. Bulking of anaerobic digestion systems can be caused by a variety of filamentous microorganisms (Hulshoff Pol et al., 2004; ...
Alternative Splicing in Higher Plants
Alternative Splicing in Higher Plants

... termination codon and transcriptional termination/polyadenylation ...
iron-regulatory protein 1
iron-regulatory protein 1

... ionic form, iron is toxic, as it can catalyse the formation of ROS (reactive oxygen species) through the Fenton reaction. These ROS damage the cell membranes, DNA and proteins [1,2]. Thus iron homoeostasis has to be tightly regulated to avoid starvation that impairs the metabolism and to avoid exces ...
QTL Mapping and Analysis for the Traits Related to Pod Dehiscence
QTL Mapping and Analysis for the Traits Related to Pod Dehiscence

... while this trait also causes major yield losses in the mechanically harvested soybeans. In this research, QTL mapping and correlation analysis of three related traits (PD trait(PDH), ratio of thickness to width (RTW) and days of full maturity (DFM) ) were performeded in 112 strains of soybean recomb ...
Got Lactase? The Co-evolution of Genes and Culture
Got Lactase? The Co-evolution of Genes and Culture

... tolerance/intolerance. Students also analyze portions of actual DNA sequences to identify the specific mutations associated with the trait. KEY CONCEPTS AND LEARNING OBJECTIVES • Mutations associated with a particular trait can be identified by comparing the DNA sequences of individuals with the tra ...
Unit 4, Lesson 10 Chromosomes and Genetics
Unit 4, Lesson 10 Chromosomes and Genetics

... duplication; this is a result of two copies being made of a portion of a chromosome. The third type is called inversion. Inversion results when a chromosome fragment is placed backwards in the chain. (Unit 4, Lesson 10 Chromosomes and Genetics Assessment 13) Does anyone know of a genetic disorder th ...
Cluster Analysis in DNA Microarray Experiments
Cluster Analysis in DNA Microarray Experiments

... Cluster analysis Clustering procedures fall into two broad categories. • Hierarchical methods, either divisive or agglomerative. These methods provide a hierarchy of clusters, from the smallest, where all objects are in one cluster, through to the largest set, where each observation is in its own c ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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