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A speculation on the origin of protein synthesis
A speculation on the origin of protein synthesis

... bound to the messenger RNA so strongly and could perhaps come off and go on again before receiving the polypeptide chain since this would only slow the process rather than make a gross error in it. A tRNA with no amino acid attached should bind rather weakly, if at all, so that it will not interfere ...
In hemoglobin Tocucci there was a replacement of the amino acid
In hemoglobin Tocucci there was a replacement of the amino acid

... In hemoglobin Tocucci there was a replacement of the amino acid histidine to tyrosine. What kind of mutation is this A. Genomic mutation. B. Aneuploidy. C. Polyploidy. D. Inversion. E. Gene (point) mutation. ANSWER E In hemoglobin Tocucci there was a replacement of the amino acid histidine to tyrosi ...
In hemoglobin Tocucci there was a replacement of the amino acid
In hemoglobin Tocucci there was a replacement of the amino acid

... Which methods of human genetics you have to use for diagnosis of Edwards syndrome? A. Genealogy method. B. Twin method C. Dermatoglyphics D. Pedigree Analysis. E. Cytogenetical method. ANSWER: E Which methods of human genetics you have to use for diagnosis of Turner syndrome? A. Genealogy method. B. ...
- Lab Fabiana Perocchi
- Lab Fabiana Perocchi

... Figure 1 Measuring allelic expression on a tiling array. (A) The array contains 25-mer probes (black and blue) that tile both strands of the genome of S288c with a probe offset of 8 bp and a 4-bp shift between the two strands. The array also contains probes (red) complementary to the YJM789 sequence ...
Synthetic Biology and the CBD
Synthetic Biology and the CBD

... it over or cause it to go extinct. Gene drives open up a a new field of species-wide population engineering where the introduction of just one fast-reproducing organism (e.g. insects, plants, small mammals, parasites) can deliberately alter entire ecosystems. The implications for the environment, fo ...


... reported for lung cancer (codon 248 CGG to CAG transition)) lung cancer developed several years after the open lung biopsy (the lung cancer specimen could not be examined for p53 mutation). Since there was no lung cancer in the lung specimen obtained by open lung biopsy, it is likely that the point ...
Is HP1 an RNA detector that functions both in repression and
Is HP1 an RNA detector that functions both in repression and

... chromosomes and how it might specify distinct activities at distinct sites. HP1 is now known to be a highly interactive protein; it is capable of interacting with a host of proteins with a range of nuclear activities (Kellum, 2003; and references therein). Do RNA sense strands recruit transcriptiona ...
FASTA is a program for database searching by homology. FASTA
FASTA is a program for database searching by homology. FASTA

... This program uses the BLASTP or BLASTN algorithms for aligning two sequences. In terms of Statistics: BLAST calculates probabilities and this can fail if some assumptions are invalid for that search. There are versions of BLAST for searching nucleic acid and protein databases, which can be used to t ...
Sequence variation in the dihydrofolate reductase
Sequence variation in the dihydrofolate reductase

... populations of any trypanosomatid parasite. We present results of a survey of nucleotide variation in the genes coding for those enzymes in a large sample of strains from Trypanosoma cruzi , the agent of Chagas’ disease. We discuss the results from an evolutionary perspective. A sample of 31 strains ...
Salmonella typhi mutants defective in anaerobic respiration are
Salmonella typhi mutants defective in anaerobic respiration are

... S. typhi must be able to adapt to the fluctuating environmental conditions encountered within the human host. There is a growing body of evidence showing that bacterial pathogens are constantly sensing their environment and adjusting to it by regulating the expression of several genes and operons. T ...
video slide - Point Pleasant Beach School District
video slide - Point Pleasant Beach School District

Two-Component System of Mycobacterium Tuberculosis
Two-Component System of Mycobacterium Tuberculosis

... phoA and phoB. The PhoP protein belongs to OmpR/PhoB subfamily, which is considered as the largest of the response regulators [32]. It contains two distinct domains: an N-terminal regulatory domain that highly conserved a phosphorylation site which receives a phosphate group from the cognate HK PhoR ...
bacterial plasmids - Acta Medica Medianae
bacterial plasmids - Acta Medica Medianae

... upon their hosts, and still they consist of nucleic acid. If we accept the proposed virus definition which says that microorganism is a single unit with continuous parentage and individual evolution history, than plasmids could be considered as live organism in spite of their simple structure (1). P ...
File
File

Foundations of Biology
Foundations of Biology

... mtDNA is much smaller than bacterial chromosomes. Mitochondrial DNA may be linear, examples include: Plasmodium, C. reinhardtii, Ochromonas, Tetrahymena, Jakoba (Gray et al., 1999). Mitochondrial genes may have introns which eubacterial genes typically lack (these introns are different from nuclear ...
Microarray data normalization and transformation
Microarray data normalization and transformation

... of gene expression by assaying the expression levels of thousands to tens of thousands of genes in a single assay. Typically, RNA is first isolated from different tissues, developmental stages, disease states or samples subjected to appropriate treatments. The RNA is then labeled and hybridized to t ...
(HPV) L1 gene DNA possibly bound to particulate aluminum
(HPV) L1 gene DNA possibly bound to particulate aluminum

... or a pair of GP5/MY09 general consensus primers. Three primer pairs were chosen to perform the second PCR to amplify multiple nests of the 450 bp MY09/MY11 PCR products in an attempt to cover possible sequence variants of the genotype-specific L1 genes that are used for manufacturing of the quadrival ...
Analysis and nucleotide sequence of an origin of DNA replication in
Analysis and nucleotide sequence of an origin of DNA replication in

... transcriptional fusions suggests that the origin of replication (or/) is contained within about 1350 bp. Analysis of ~-galactosidase production in A. calcoaceticus indicates that only a weak promoter activity is directed out of one end of this or/. Its sequence contains A + T-rich regions, an 18-bp ...
A large scale analysis of resistance gene
A large scale analysis of resistance gene

... A. thaliana for resistance to Pseudomonas syringae (gi 15221252), R-gene Mi-1 against nematodes and aphids from Lycopersicon esculentum (gi 7489037) and gene Rpp 8 of A. thaliana (gi 17064876). The sequence of primer RNBS-D-rev was kindly provided by Nevin Young. Primer LM638 was developed by Kanazi ...
functional analysis of chromatin assembly genes in tetrahymena
functional analysis of chromatin assembly genes in tetrahymena

... The basic structural unit of chromatin is the nucleosome composed of ~147 base pairs of DNA wrapped around an octamer of histone proteins. Post-translational modifications such as histone acetylation or the substitution of histone variants in place of core histones have been implicated in various ch ...
The Rat Gene Map
The Rat Gene Map

... segments found when either species is compared with human. It should be kept in mind that these calculations are very approximate due to the scarcity of data, but they might still provide hints of genomic relationships among the 3 species. Thus, what appears to be a considerable amount of genome rea ...
Tools Enabling Metabolic Parents LEarning
Tools Enabling Metabolic Parents LEarning

... sperm of the father. The genes on those chromosomes carry the instruction that determines characteristics, which are a combination of the parents. ...
continued
continued

... 10.1 What Is the Physical Basis of Inheritance?  Genes are sequences of nucleotides at specific locations on chromosomes – Inheritance is the process by which the characteristics of individuals are passed to their offspring – A gene is a unit of heredity that encodes information needed to produce ...
The genetic causes of convergent evolution
The genetic causes of convergent evolution

... represent substitutions of the A allele by the T allele throughout the population. b | An example of parallel evolution is shown: the monarch butterfly caterpillar (top left), the red milkweed beetle (top right), oleander aphids (bottom left) and the large milkweed beetle (bottom right), among other ...
11-1
11-1

... These plants were “true-breeding,” meaning that they were selfpollinating, and would produce offspring identical to themselves. In other words, the traits of each successive generation would be the same. A trait is a specific characteristic, such as seed color or plant height, of an individual. Many ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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