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... • inactive one is designated Xi • if multiple X chromosomes are present (i.e. 3 vs. 2) – only one X chromosome is still Xa – default state is the inactive form • hypothesis: autosomally-encoded blocking factor binds to the Xa chromosome and prevents its inactivation – sequence known as the XIC – X i ...
Polyploidy and genome evolution in plants
Polyploidy and genome evolution in plants

... of genome doubling, how is it that the evolutionary process has forged modern genomes as small as those of Arabidopsis, or with gene numbers that are far less than that expected by the doubling process per se? The answer appears to be that polyploidy is followed by a genomewide removal of some but n ...
Epigenetics
Epigenetics

... design of a simple antibody-based detection method, not unlike test-strip kits that are currently used for pregnancy tests ...
Neurospora genetic nomenclature
Neurospora genetic nomenclature

... 1.5. Genes in ectopic positions. A Neurospora gene that has been integrated ectopically is designated by appending (EC) to the gene symbol, e.g., am(EC). The genotype of a strain with a gene deleted from its normal position and a wild type copy of the same gene inserted elsewhere in the genome would ...
Functional dissection of the baculovirus late expression factor
Functional dissection of the baculovirus late expression factor

... (Guarino et al., 1998b) and, potentially, to modify the 59 (Gross & Shuman, 1998; Guarino et al., 1998a; Jin et al., 1998) and 39 ends (Jin & Guarino, 2000) of transcripts. Although the specific role of each subunit in transcription is not known, the product of lef-4 (LEF-4) has RNA 59triphosphatase ...
DNA Technology - De Anza College
DNA Technology - De Anza College

... Via genetic engineering… • Recombinant DNA techniques are used • To clone cellulase genes in bacteria • To produce large quantities of cellulase To sell to textile manufacturers ...
Diffuse Nonepidermolytic Palmoplantar Keratoderma Caused by a
Diffuse Nonepidermolytic Palmoplantar Keratoderma Caused by a

... manifesting with prominent PPK. Over the last several years, much progress has been achieved toward a better understanding of the molecular basis of these disorders. Mutations in more than 20 distinct genes have been described in various forms of PPK. Many of these genes code for structural proteins ...
Chromosomes
Chromosomes

... settings–is called cytogenetics. There are two major tools used in cytogenetics today. The first is the karyotype which is literally a picture of the stained chromosomes that can be viewed under the light (or fluorescent) microscope. The second is a procedure called fluorescent in situ hybridization ...
Genetics Heredity and Variation: *Heredity is the branch of science
Genetics Heredity and Variation: *Heredity is the branch of science

... The “Central Dogma ”in prokaryotic cells In prokaryotes, in the absence of nuclear membrane, DNA Transcription and RNA Translation are not physically separated, the RNA Transcript can directly ...
Advanced Plant Technology Program Vocabulary
Advanced Plant Technology Program Vocabulary

... Photosynthesis (noun): The process by which plants convert sunlight into sugar for food. Phylogenetics (noun): The study of evolutionary relationships between groups of organisms using DNA sequencing data for comparison. Phylogeography (noun): The study of the processes that may be responsible for t ...
Genetics
Genetics

... e. Purebred refers to an organism with a pair of the same genes for a given trait (either dominant or recessive). This is known as being homozygous. f. Hybrid refers to an organism with two different genes for a trait (one dominant and one recessive). This is known as being heterozygous. ...
GeneticsTeachPrep
GeneticsTeachPrep

... A gene provides the instructions for making a protein. Different versions of a gene are called alleles; different alleles give the instructions for making different versions of a protein. The different versions of a protein can result in different phenotypic characteristics. Each cell has two copies ...
ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

... Eukaryotic genomes Transcription of protein-encoding regions is initiated at specific promoter sequences, and followed by removal of noncoding sequence (introns) from pre-mRNA by a splicing mechanism. 3 types of posttranscriptional events influence the translation of mRNA into protein and the accur ...
Study Guide Genetics
Study Guide Genetics

... even  have  a  chance  of  being  colorblind.  There  is  a  fairly  high  chance  that  if  the  woman  is  a  carrier   for  the  colorblindedness  trait,  that  it  would  be  masked  by  the  dominant  allele  for  normal  vision.     ...
Title, arial 30pt Bold, all caps
Title, arial 30pt Bold, all caps

... stranded DNA molecule using a DNA polymerase enzyme that is tolerant to elevated temperatures • PCR is used to amplify a specific region (sequence) of a DNA strand (the DNA target) within a genome. • The amount of amplified product is determined by the available substrates (reagents) in the reaction ...
Fact Sheet 31 | CANCER GENETICS OVERVIEW This fact sheet
Fact Sheet 31 | CANCER GENETICS OVERVIEW This fact sheet

... cell contains a complete copy of our genetic information or DNA. Our DNA contains the instructions for growth and development and is packaged into chromosomes that contain all our genes. Genes provide a code for the proteins our body needs to function. We all have two copies of every gene, one that ...
Document
Document

... • Because eukaryotes have pairs of chromosomes, a genotype for a gene has two alleles. • If the two alleles have the same information, the genotype is homozygous. • If the two alleles have different information, the genotype is heterozygous. ...
12.2 * What is Heredity?
12.2 * What is Heredity?

... The symbol for a dominant allele is an uppercase letter. The symbol for a recessive allele is a lowercase letter. ...
D. PCR - Pass the FracP
D. PCR - Pass the FracP

... Using linkage analysis to identify region of gene Searching for unknown gene Identifying genes without knowledge of function ...
Heredity
Heredity

... offspring gets one allele of the pair from the mom and one allele of the pair from the dad. ...
When Is Hub Gene Selection Better than
When Is Hub Gene Selection Better than

... When does hub gene selection lead to more meaningful gene lists than a standard statistical analysis based on significance testing? • Here we address this question for the special case when multiple data sets are available. • This is of great practical importance since for many research questions m ...
Why have organelles retained genomes?
Why have organelles retained genomes?

... genome reduction, three possible fates awaited genes encoded therein: (1) some genes encoding proteins required to support existence as a free-living cell were forever lost during the course of reductive evolution; (2) many genes were transferred to what is now the nuclear genome; or (3) a small sub ...
Chapter 4 - Genetic Principles
Chapter 4 - Genetic Principles

... Besides complete dominance, there are other types of in- including birth weight and pelvic area, which are both polygenic teractions between the two alleles at a locus, including: partial traits that are expressed on a continuous scale. Continuous refers dominance, no dominance, and overdominance. A ...
Introduction to Oncogenesis by RNA Tumor Viruses
Introduction to Oncogenesis by RNA Tumor Viruses

... their estimated molecular weight, e.g. murine p30 denotes the major core protein of 30000 daltons of murine leukemia virus (MuLV). Precursor polypeptides are similarly labeled pr65, or pr90, etc. The env gene encodes the proteins located in the envelope of the virion which is derived by budding from ...
- Higher Education Academy
- Higher Education Academy

... direct precursor of that of Gregor Mendel, working at Brno in Czechoslovakia, about 40 years after Goss. Mendel’s extensive and systematic experiments on peas in the monastery garden, coupled with a detailed numerical analysis of the results led to confirmation of recessive and dominant inheritance ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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