Implementation of molecular markers for quantitative traits in
... multiple disease resistance gene pyramids combined in one genotype (where they can epistatically mask each other’s effects), alleles that are not expressed in the selection environments (e.g., genes conferring resistance to a disease that is not regularly present in environments), or genes whose phe ...
... multiple disease resistance gene pyramids combined in one genotype (where they can epistatically mask each other’s effects), alleles that are not expressed in the selection environments (e.g., genes conferring resistance to a disease that is not regularly present in environments), or genes whose phe ...
Genome Visualisation and Annotation Tools: Artemis and ACT
... This is the main sequence view panel. The central 2 grey lines represent the forward (top) and reverse (bottom) DNA strands. Above and below those are the 3 forward and 3 reverse reading frames. Stop codons are marked as black vertical bars. Genes and other features (eg. Pfam and Prosite matches) ar ...
... This is the main sequence view panel. The central 2 grey lines represent the forward (top) and reverse (bottom) DNA strands. Above and below those are the 3 forward and 3 reverse reading frames. Stop codons are marked as black vertical bars. Genes and other features (eg. Pfam and Prosite matches) ar ...
Boundless Study Slides
... Key terms • chromosome a structure in the cell nucleus that contains DNA, histone protein, and other structural proteins • dominant a relationship between alleles of a gene, in which one allele masks the expression (phenotype) of another allele at the same locus • epistasis the modification of the e ...
... Key terms • chromosome a structure in the cell nucleus that contains DNA, histone protein, and other structural proteins • dominant a relationship between alleles of a gene, in which one allele masks the expression (phenotype) of another allele at the same locus • epistasis the modification of the e ...
Assessment of the mosaic structure in the
... amplicons are sequenced using a battery of gene specific primers (often the PCR primers). In a recent study, we described an improved strategy using M13 and T7 sequence tagged primers in PCR amplification covering the cagA EPIYA motifs. Tagging of the PCR primers enables rapid sequencing using unive ...
... amplicons are sequenced using a battery of gene specific primers (often the PCR primers). In a recent study, we described an improved strategy using M13 and T7 sequence tagged primers in PCR amplification covering the cagA EPIYA motifs. Tagging of the PCR primers enables rapid sequencing using unive ...
Population Differences in the Polyalanine Domain and 6
... likely lead to loss of the signal for initiation of translation, suggesting either that no protein is produced or the translation initiation site moves up- or downstream. In HLXB9, the next in-frame ATG codon would correspond to methionine 223. Translation initiation from this internal ATG site woul ...
... likely lead to loss of the signal for initiation of translation, suggesting either that no protein is produced or the translation initiation site moves up- or downstream. In HLXB9, the next in-frame ATG codon would correspond to methionine 223. Translation initiation from this internal ATG site woul ...
Natural selection shaped regional mtDNA
... mtDNA coding region (nucleotide positions 577–16023), because of the high probability of reverse mutations in the control region. The average sequence evolution rate was estimated by using the HKY85 model (14). Standard errors were calculated from the inverse hessian at the maximum of the likelihood ...
... mtDNA coding region (nucleotide positions 577–16023), because of the high probability of reverse mutations in the control region. The average sequence evolution rate was estimated by using the HKY85 model (14). Standard errors were calculated from the inverse hessian at the maximum of the likelihood ...
Journal Club Pack - Circulation Research
... pELK-1, KLF4, and HDAC2, with the latter contributing to histone hypo-acetylation, chromatin remodeling, and transcriptional silencing. Studies provide novel evidence that phenotypic switching of SMC in vivo is mediated, at least in part, by binding of the stem cell pluripotency factor KLF4 to a G/C ...
... pELK-1, KLF4, and HDAC2, with the latter contributing to histone hypo-acetylation, chromatin remodeling, and transcriptional silencing. Studies provide novel evidence that phenotypic switching of SMC in vivo is mediated, at least in part, by binding of the stem cell pluripotency factor KLF4 to a G/C ...
Creation/Evolution
... There are thus a total of 22 unique meanings for the 64 codons, so many codons are synonyms. The fact that many amino acids are coded for by several codons is called degeneracy ©2000 Timothy G. Standish ...
... There are thus a total of 22 unique meanings for the 64 codons, so many codons are synonyms. The fact that many amino acids are coded for by several codons is called degeneracy ©2000 Timothy G. Standish ...
video slide
... • In calculating the chances for various genotypes, each character is considered separately, and then the individual probabilities are multiplied together Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings ...
... • In calculating the chances for various genotypes, each character is considered separately, and then the individual probabilities are multiplied together Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings ...
Metabolic rate depression in animals
... becomes intermittent, and kidney filtration rate is reduced. Organisms do not eat so the energetic costs of digestion, nutrient absorption, and peristalsis are eliminated. A substantial part of total energy savings comes from the suppression of these physiological activities. Metabolic rate is also i ...
... becomes intermittent, and kidney filtration rate is reduced. Organisms do not eat so the energetic costs of digestion, nutrient absorption, and peristalsis are eliminated. A substantial part of total energy savings comes from the suppression of these physiological activities. Metabolic rate is also i ...
Recombination and epistasis facilitate introgressive hybridization
... affecting hybridization, because linkage equilibrium is recovered only by recombination, and it influences the efficacy of selection purging incompatible sets of exotic genes. As a modelling framework that ensures manipulation of recombination to examine the effect of recombination on introgressive ...
... affecting hybridization, because linkage equilibrium is recovered only by recombination, and it influences the efficacy of selection purging incompatible sets of exotic genes. As a modelling framework that ensures manipulation of recombination to examine the effect of recombination on introgressive ...
Novel evolutionary lineages of the invertebrate oxytocin/vasopressin
... The sixth and seventh TM domains are highly conserved among known receptors of the OT/VP superfamily in vertebrates, as well as invertebrates. To identify receptors for OP and CT in octopus, three degenerate primers were designed based on the conserved regions, and RT-PCRs were performed between the ...
... The sixth and seventh TM domains are highly conserved among known receptors of the OT/VP superfamily in vertebrates, as well as invertebrates. To identify receptors for OP and CT in octopus, three degenerate primers were designed based on the conserved regions, and RT-PCRs were performed between the ...
Genes involved in asexual sporophyte development in Ceratopteris
... flower organs or seed structures, both of which are absent in ferns. One of these genes, UNC93-like, is also expressed in the eggs of C. richardii gametophytes, as evidenced by ...
... flower organs or seed structures, both of which are absent in ferns. One of these genes, UNC93-like, is also expressed in the eggs of C. richardii gametophytes, as evidenced by ...
Effect of the Polymorphisms of Keratin Associated Protein 8.2 Gene
... ABSTRACT : The aim of the experiment was to detect polymorphisms in the keratin-associated protein 8.2 (KAP8.2) gene to determine associations between the genotype and fibre traits in Chinese Inner Mongolia cashmere goats. The fibre traits data investigated were cashmere fibre diameter, combed cashm ...
... ABSTRACT : The aim of the experiment was to detect polymorphisms in the keratin-associated protein 8.2 (KAP8.2) gene to determine associations between the genotype and fibre traits in Chinese Inner Mongolia cashmere goats. The fibre traits data investigated were cashmere fibre diameter, combed cashm ...
Monday, November 17, 2014 Agenda: Cell Organelle Analogy
... organized in chromosomes. – Genes have specific places on chromosomes. ...
... organized in chromosomes. – Genes have specific places on chromosomes. ...
org.Dr.eg.db
... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
video slide - Biology at Mott
... Inheritance patterns are often more complex than predicted by simple Mendelian genetics • The relationship between genotype and phenotype is rarely as simple as in the pea plant characters Mendel studied • Many heritable characters are not determined by only one gene with two alleles • However, the ...
... Inheritance patterns are often more complex than predicted by simple Mendelian genetics • The relationship between genotype and phenotype is rarely as simple as in the pea plant characters Mendel studied • Many heritable characters are not determined by only one gene with two alleles • However, the ...
PDF
... INTRODUCTION The H19 gene was cloned 20 years ago (Pachnis et al., 1988) and was one of the first imprinted genes to be identified. Genomic imprinting is an epigenetic mechanism that leads to parent-of-origin specific monoallelic expression. Thus, H19 is expressed from the maternal allele in mouse a ...
... INTRODUCTION The H19 gene was cloned 20 years ago (Pachnis et al., 1988) and was one of the first imprinted genes to be identified. Genomic imprinting is an epigenetic mechanism that leads to parent-of-origin specific monoallelic expression. Thus, H19 is expressed from the maternal allele in mouse a ...
Biotechnology Timeline
... The genetic code for DNA is cracked, demonstrating that a sequence of three nucleotide bases (a codon) determines each of 20 amino acids. Three scientists shared the 1968 Nobel Prize in Physiology or Medicine for the discovery. ...
... The genetic code for DNA is cracked, demonstrating that a sequence of three nucleotide bases (a codon) determines each of 20 amino acids. Three scientists shared the 1968 Nobel Prize in Physiology or Medicine for the discovery. ...
Neonatal Hyperbilirubinemia and Organic Anion Transporting
... hyperbilirubinemia in the neonatal period, and a family history that suggests an underlying genetic cause. An increasing number of studies have focused on the genetics of bilirubin; these studies have sought to detect genetic mutations that lead to elevated unconjugated serum bilirubin, such as thos ...
... hyperbilirubinemia in the neonatal period, and a family history that suggests an underlying genetic cause. An increasing number of studies have focused on the genetics of bilirubin; these studies have sought to detect genetic mutations that lead to elevated unconjugated serum bilirubin, such as thos ...
Thalassemias
... b thalassemias are autosomal inherited disorders of b globin synthesis. In most, globin structure is normal but the rate of production is reduced because of decrease in transcription of DNA, abnormal processing of premRNA, or decreased translation of mRNA leading to decreased Hb-A production (A=Ad ...
... b thalassemias are autosomal inherited disorders of b globin synthesis. In most, globin structure is normal but the rate of production is reduced because of decrease in transcription of DNA, abnormal processing of premRNA, or decreased translation of mRNA leading to decreased Hb-A production (A=Ad ...
Study on the Genetic Transformation of Gentian by Gene Recombinant
... roots, the best concentrate is 20 μｍ, but the rate only raised 10% compared with the one without AS. The effect wasn't obvious. ...
... roots, the best concentrate is 20 μｍ, but the rate only raised 10% compared with the one without AS. The effect wasn't obvious. ...
PHANTASTICA Regulates Development of the Adaxial Mesophyll in
... is shown in Figure 1 with identical residues shaded. All have a highly conserved MYB DNA binding domain at the N terminus, consisting of two imperfect repeats (55 and 51 residues), both of which are essential for sequence-specific DNA binding based on structural analysis of c-MYB (Jin and Martin, 19 ...
... is shown in Figure 1 with identical residues shaded. All have a highly conserved MYB DNA binding domain at the N terminus, consisting of two imperfect repeats (55 and 51 residues), both of which are essential for sequence-specific DNA binding based on structural analysis of c-MYB (Jin and Martin, 19 ...
Genome partitioning of genetic variation for complex traits using
... highly polygenic traits, and that the additive variation explained by a part of the genome is approximately proportional to the total length of DNA contained within genes therein. Genome-wide association studies (GWAS) have led to the discovery of hundreds of marker loci that are associated with co ...
... highly polygenic traits, and that the additive variation explained by a part of the genome is approximately proportional to the total length of DNA contained within genes therein. Genome-wide association studies (GWAS) have led to the discovery of hundreds of marker loci that are associated with co ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.