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The endogenous molecular clock orchestrates the temporal
The endogenous molecular clock orchestrates the temporal

... Skeletal muscle plays a large role in whole-body metabolism as it constitutes approximately 40% of body mass and is a highly metabolically active tissue [1,2]. Basal metabolic rate is dependent on both the size and activity of skeletal muscle as cross-bridge cycling and calcium handling associated w ...
Chapter 2
Chapter 2

... The common management strategy has been to replace cultivars when their resistance is no longer effective ( Wolf, 1984, Leath & Heun, 1990). Molecular markers, tightly linked to disease resistance genes, can provide breeders with a tool for marker-assisted selection of resistance gene in plants (Stu ...
JunctionSeq Package User Manual
JunctionSeq Package User Manual

... Under the default parameterization, JunctionSeq also builds upon and expands the basic design put forth by DEXSeq, providing (among other things) the ability to test for both differential exon usage and differential splice junction usage. These two types of analyses are complementary: Exons represen ...
nitrogen assimilation and global regulation in escherichia coli
nitrogen assimilation and global regulation in escherichia coli

... Annu. Rev. Microbiol. 2003.57:155-176. Downloaded from arjournals.annualreviews.org by WIB6332 - University of Saarland on 01/04/10. For personal use only. ...
File
File

... Dominant traits are apparent only when two recessive alleles for the characteristic are inherited. A genotype is the combination of alleles for a particular trait The set of instructions transmitted to parent to offspring are called genes. Gregor Mendel used dandelions to study heredity. Heredity is ...
Genomic Databases for Tomato
Genomic Databases for Tomato

... Information concerning various biological aspects such as functional annotations of genes and gene products, intron-exon structures, gene expressions and metabolic pathways is available from various tomatorelated web sites. These public data advance not only functional genomics but also the emerging ...
Evidence from glycine transfer RNA of a frozen accident at the dawn
Evidence from glycine transfer RNA of a frozen accident at the dawn

... A37 has been replaced by G, perhaps because of a general increase in G+C content in the tRNA and rRNA of these species [18]. There are three other sequences not containing an anticodon loop CCA that appear to be isolated examples, but in these cases their origin is unclear. Schimmel's experimental w ...
Chapter 4 - DORAS
Chapter 4 - DORAS

... characterised as a haem uptake system for this organism (Letoffe et al., 2006). In E. coli the dipeptide inner membrane transport system consists of the ATP dependent transport system DppBCDF and two competitively binding periplasmic binding proteins MppA and DppA that bind dipeptides competitively. ...
Recall Questions
Recall Questions

... *35. A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, th ...
Multi-petal cyclamen flowers produced by
Multi-petal cyclamen flowers produced by

... although the transcripts of each gene were also detected in stamen, carpel and receptacle6. Chimeric repressor gene-silencing technology (CRES-T) provides a powerful tool for dominant negative genetic modification of a transcription factor. In CRES-T, a short but strong, plant-specific transcription ...
using the crispr/cas9 gene editing tool to develop a cure for
using the crispr/cas9 gene editing tool to develop a cure for

... Berkeley, was able to combine these two into one complete molecule—one that is now the most commonly used form of CRISPR [6]. The other component is the Cas9 enzyme, which binds to the location determined by the guide RNA, and then performs the cutting of the target gene. The first step in the proce ...
Genetic Crosses
Genetic Crosses

... Explain how probability is used to predict the results of genetic crosses. Use a Punnett square to predict the results of monohybrid and dihybrid genetic crosses. Explain how a testcross is used to show the genotype of an individual whose phenotype is dominant. Differentiate a monohybrid cross from ...
GENETIC GUIDELINES for - Lake Superior State University
GENETIC GUIDELINES for - Lake Superior State University

... Whenever a cell divides, the DNA must be replicated in order to provide each daughter cell with a complete set of genes. An advantage of complementary base pairing is evident during replication of the DNA molecule. During replication, the two strands of the DNA helix are separated by enzymes so tha ...
Small Nucleolar RNA
Small Nucleolar RNA

... • Loss of either the paternal or maternal copy of this region leads to two neurological disorders: Prader-Willi or Angelman ...
Patent constraints
Patent constraints

... ID numbering) that each claimed approximately 2000 sequences, many of which did not have well-characterised functions in 1998 (that can be inferred from the reference list). CIPs have been filed as functions have become clear, and continuations are being kept alive for those for which the functions ...
PDF
PDF

... can explain only up to 1.5% of the variance in BMI.4 The first “obesogenic” SNP to be replicated and validated was the fat mass and obesity-associated (FTO) gene consisting of nine exons on chromosome 16 (16q12.2).5 It encodes a 2-oxoglutarate-dependent nucleic acid demethylase6 and is found in high ...
Systematic Studies on the Family Cucurbitaceae
Systematic Studies on the Family Cucurbitaceae

... to determine seed size for the long, medium, and short classes (ll SS for long, LL SS for medium, and LL ss or ll ss for short). The tomato seed size was studied in a cross between a 'Sugar Baby' mutant with tomato seed size and 'GN-1', with short seeds. The tomato seed size trait was inherited as ...
Candidate gene scan for Single Nucleotide Polymorphisms involved
Candidate gene scan for Single Nucleotide Polymorphisms involved

... extraordinary variety of human facial appearances, in the same way that genes responsible for ...
Recombinant DNA technology and molecular cloning
Recombinant DNA technology and molecular cloning

A genome-wide association scan in pig identifies novel regions
A genome-wide association scan in pig identifies novel regions

... pig QTLdb on various SSC (9, 13, 16, 18, and X). Such linkage information can be used only for within-family selection, and the linkage QTL intervals are generally wide and therefore are not suitable for candidate gene searches. However, association mapping (also known as linkage disequilibrium mapp ...
1. True or False? The standard human karotype consists of 23 pairs
1. True or False? The standard human karotype consists of 23 pairs

... A.  the X chromosome inherited from the father is lost early in development.   B.  females are heterogametic, XY.   C.  females are always X0, and inherit sex chromosome from the mother.   D.  the inactivated X chromosome is always the one contributed by the mother.   E.  the inactivated X chromosom ...
Use of a novel cassette to label phenotypically a cryptic plasmid of
Use of a novel cassette to label phenotypically a cryptic plasmid of

... isolated on a Sau3A fragment which on insertion at a BamHI site regenerates a BamHI site at the downstream end-of-thetermin~i-^(GiTpAPG3,Fig. 1). However, downstream of the rrnBt, tz terminators from pKK223-3 there is no convenient restriction site before the bla promoter at position 4189 of the pBR ...
Genome-wide search for signatures of selection in three
Genome-wide search for signatures of selection in three

... Brazilian sheep are descendants of animals imported during the colonization period and, since then, have been subject to systematic and non-systematic evolutionary processes. This has led to the development of local breeds adapted to the diverse Brazilian environmental conditions (Mariante et al., 2 ...
Genetics of mammalian meiosis: regulation, dynamics and impact
Genetics of mammalian meiosis: regulation, dynamics and impact

... chromosomes begin to align but are not yet paired. A chromosomal scaffold begins to form through the assembly of axial elements (AEs) from cohesin proteins (for example, REC8 and structural maintenance of chromosomes 1B (SMC1B)) and synaptonemal complex (SC)-specific proteins, such as SYCP3 and SYCP ...
University of Groningen Stress responses and sugar metabolism in
University of Groningen Stress responses and sugar metabolism in

... In  addition  to  these  phosphoproteins  also  low  molecular  weight  molecules  such  as  NADP,  glucose‐6‐phosphate  (G6P)  and  fructose‐1,6‐bisphosphate  (FBP)  can  modulate  either  DNA‐ binding  properties  or  the  interaction  with  the  transcriptional  machinery  of  the  CcpA‐(HPr‐ Ser ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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