An organism containing a normal chromosome complement and
... production of somatic cells or gametes with an extra chromosome. chromosome Interspecific hybrids often produce trisomic plants in their segregating progeny. ...
... production of somatic cells or gametes with an extra chromosome. chromosome Interspecific hybrids often produce trisomic plants in their segregating progeny. ...
Analysis of Genetic Toggle Switch Systems Encoded on Plasmids
... ing time , namely, the average time between spontaneous transitions. Two variants, the general switch and the exclusive switch, were studied and compared in Refs. [27]. The difference between these two variants is that in the exclusive switch there is an overlap between the two promoter sites, so t ...
... ing time , namely, the average time between spontaneous transitions. Two variants, the general switch and the exclusive switch, were studied and compared in Refs. [27]. The difference between these two variants is that in the exclusive switch there is an overlap between the two promoter sites, so t ...
Telomereled bouquet formation facilitates homologous chromosome
... formed between sister chromatids that were produced by a mechanism coupled with semiconservative DNA replication (Skibbens et al., 1999; Toth et al., 1999). In meiosis, however, the link is typically formed between homologous chromosomes, each of which was brought into the same cell from previously ...
... formed between sister chromatids that were produced by a mechanism coupled with semiconservative DNA replication (Skibbens et al., 1999; Toth et al., 1999). In meiosis, however, the link is typically formed between homologous chromosomes, each of which was brought into the same cell from previously ...
Bio-session package - Social Science Genetic Association Consortium
... association studies, each cost around $10 million or more. The results of this costly international exercise have been disappointing. About 2,000 sites on the human genome have been statistically linked with various diseases, but in many cases the sites are not inside working genes, suggesting there ...
... association studies, each cost around $10 million or more. The results of this costly international exercise have been disappointing. About 2,000 sites on the human genome have been statistically linked with various diseases, but in many cases the sites are not inside working genes, suggesting there ...
Parasitism and Mutualism in Wolbachia: What the
... reduced, studies specify that discrete symbiotic associations can be evolutionarily stable for hundreds of millions of years. Wolbachia is an inherited obligate, intracellular infection of invertebrates containing taxa that act broadly as both parasites in arthropods and mutualists in certain roundw ...
... reduced, studies specify that discrete symbiotic associations can be evolutionarily stable for hundreds of millions of years. Wolbachia is an inherited obligate, intracellular infection of invertebrates containing taxa that act broadly as both parasites in arthropods and mutualists in certain roundw ...
CH Zinc Fingers As DNA Binding Domains
... is usefiil to predict how the zinc fingers of the proteins exert their binding activity. The single zinc finger differs from the other zinc fingers in that it requires an additional, non-zinc finger domain to establish the binding to the target DNA.^^ The other classes, that is the triple, multiple- ...
... is usefiil to predict how the zinc fingers of the proteins exert their binding activity. The single zinc finger differs from the other zinc fingers in that it requires an additional, non-zinc finger domain to establish the binding to the target DNA.^^ The other classes, that is the triple, multiple- ...
Gene Name
... encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes. Same as APEX1 or APEX nuclease (multifunctional DNA repair enzyme) 1. Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that ...
... encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes. Same as APEX1 or APEX nuclease (multifunctional DNA repair enzyme) 1. Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that ...
Andrew Phillips
... Perform in silico experiments on biological system models Use these to formulate testable hypotheses for experimentation in vivo ...
... Perform in silico experiments on biological system models Use these to formulate testable hypotheses for experimentation in vivo ...
Oliver, B., Kim, Y.-J., and Baker, B. S.
... cells and to order the functioning of other genes involved in germ-line sex determination relative to Sxl+. We first examined whether the sex specificity of Sxl+ function in the germ line was associated with sex-specific patterns of pre-mRNA splicing identical to those used to control Sxl+ activity ...
... cells and to order the functioning of other genes involved in germ-line sex determination relative to Sxl+. We first examined whether the sex specificity of Sxl+ function in the germ line was associated with sex-specific patterns of pre-mRNA splicing identical to those used to control Sxl+ activity ...
www.psd150.org
... Mendel crossed some yellow peas with some yellow peas. Most offspring were yellow but some were green! ...
... Mendel crossed some yellow peas with some yellow peas. Most offspring were yellow but some were green! ...
video slide
... Concept 14.3: Inheritance patterns are often more complex than predicted by simple Mendelian genetics • The relationship between genotype and phenotype is rarely as simple as in the pea plant characters Mendel studied • Many heritable characters are not determined by only one gene with two alleles ...
... Concept 14.3: Inheritance patterns are often more complex than predicted by simple Mendelian genetics • The relationship between genotype and phenotype is rarely as simple as in the pea plant characters Mendel studied • Many heritable characters are not determined by only one gene with two alleles ...
LINKAGE AND MAPPING IN EUKARYOTES
... fter Sutton suggested the chromosomal theory of inheritance in 1903, evidence accumulated that genes were located on chromosomes. For example, Morgan showed by an analysis of inheritance patterns that the white-eye locus in Drosophila is located on the X chromosome. Given that any organism has many ...
... fter Sutton suggested the chromosomal theory of inheritance in 1903, evidence accumulated that genes were located on chromosomes. For example, Morgan showed by an analysis of inheritance patterns that the white-eye locus in Drosophila is located on the X chromosome. Given that any organism has many ...
Molecular events during translocation and proofreading extracted
... (3). This DNA polymerase incorporates hundreds of nucleotides to a primer strand in each second under instructions of a template strand (4–6). At the most fundamental level of the polymerase mechanism, this enzyme transfers a phosphoryl bond on P␣ of an incoming deoxyribonucleoside triphosphate (dNT ...
... (3). This DNA polymerase incorporates hundreds of nucleotides to a primer strand in each second under instructions of a template strand (4–6). At the most fundamental level of the polymerase mechanism, this enzyme transfers a phosphoryl bond on P␣ of an incoming deoxyribonucleoside triphosphate (dNT ...
Genome-Wide Copy Number Variation in Epilepsy: Novel
... Epilepsy is one of the most common neurological disorders in humans with a prevalence of 1% and a lifetime incidence of 3%. Several genes have been identified in rare autosomal dominant and severe sporadic forms of epilepsy, but the genetic cause is unknown in the vast majority of cases. Copy number ...
... Epilepsy is one of the most common neurological disorders in humans with a prevalence of 1% and a lifetime incidence of 3%. Several genes have been identified in rare autosomal dominant and severe sporadic forms of epilepsy, but the genetic cause is unknown in the vast majority of cases. Copy number ...
Variability of polyphenol oxidase (PPO) alleles located on
... Using the dominant STS marker STS01, we did not detect allelic segregation of PPO genes on chromosome 2DL in any of the 300 F4 plants obtained from the hybridization of Yangmai 158 and Huaimai 18, possibly due to the similar genetic background of this population. However, in this population, the all ...
... Using the dominant STS marker STS01, we did not detect allelic segregation of PPO genes on chromosome 2DL in any of the 300 F4 plants obtained from the hybridization of Yangmai 158 and Huaimai 18, possibly due to the similar genetic background of this population. However, in this population, the all ...
Biochemical but not clinical vitamin A deficiency results from
... Circulating retinol serves as a metabolic precursor of retinal and retinoic acid, and its subsequent cellular uptake is the predominant source of vitamin A for target cells. Many organs, such as the liver, kidney, small intestine, lung, spleen, eye, and testis, depend on a regular supply of vitamin ...
... Circulating retinol serves as a metabolic precursor of retinal and retinoic acid, and its subsequent cellular uptake is the predominant source of vitamin A for target cells. Many organs, such as the liver, kidney, small intestine, lung, spleen, eye, and testis, depend on a regular supply of vitamin ...
Identity elements in tRNA-mediated transcription
... Fig. 3. Effect of native and chimeric tRNAs on transcription antitermination in the trpE-lacZ fusion. RNA was isolated from L. lactis cells after a growth medium shift as indicated in Methods and used to prepare a Northern blot that was hybridized with a lacZ-specific probe to visualize full length ...
... Fig. 3. Effect of native and chimeric tRNAs on transcription antitermination in the trpE-lacZ fusion. RNA was isolated from L. lactis cells after a growth medium shift as indicated in Methods and used to prepare a Northern blot that was hybridized with a lacZ-specific probe to visualize full length ...
Identity elements in tRNA-mediated transcription
... Fig. 3. Effect of native and chimeric tRNAs on transcription antitermination in the trpE-lacZ fusion. RNA was isolated from L. lactis cells after a growth medium shift as indicated in Methods and used to prepare a Northern blot that was hybridized with a lacZ-specific probe to visualize full length ...
... Fig. 3. Effect of native and chimeric tRNAs on transcription antitermination in the trpE-lacZ fusion. RNA was isolated from L. lactis cells after a growth medium shift as indicated in Methods and used to prepare a Northern blot that was hybridized with a lacZ-specific probe to visualize full length ...
DNA Base Sequence Homology in Rhizoctonia solani Kuihn: Inter
... AG-10 (12). Some of these anastomosis groups are further subdivided based on pathogenicity (AG-1, AG-2), colony morphology (AG-1), thiamine requirement (AG-2, AG-9), and/or DNA homology (AG-4, AG-6) into intraspecific groups (ISG) (11). The ISG is derived by combining anastomosis group affiliation w ...
... AG-10 (12). Some of these anastomosis groups are further subdivided based on pathogenicity (AG-1, AG-2), colony morphology (AG-1), thiamine requirement (AG-2, AG-9), and/or DNA homology (AG-4, AG-6) into intraspecific groups (ISG) (11). The ISG is derived by combining anastomosis group affiliation w ...
SEQUENCE COMPLIANCE SOUP TO NUTS
... – Sequences having a gap or gaps must be displayed as separate sequences in the Sequence Listing. For example, if a chemical moiety has several strands of protein attached to it, each protein sequence should appear in the Sequence Listing separately. The chemical moiety should NOT be shown (37 CFR 1 ...
... – Sequences having a gap or gaps must be displayed as separate sequences in the Sequence Listing. For example, if a chemical moiety has several strands of protein attached to it, each protein sequence should appear in the Sequence Listing separately. The chemical moiety should NOT be shown (37 CFR 1 ...
sequence compliance soup to nuts
... – Sequences having a gap or gaps must be displayed as separate sequences in the Sequence Listing. For example, if a chemical moiety has several strands of protein attached to it, each protein sequence should appear in the Sequence Listing separately. The chemical moiety should NOT be shown (37 CFR 1 ...
... – Sequences having a gap or gaps must be displayed as separate sequences in the Sequence Listing. For example, if a chemical moiety has several strands of protein attached to it, each protein sequence should appear in the Sequence Listing separately. The chemical moiety should NOT be shown (37 CFR 1 ...
Review A model for chromosome structure during the mitotic
... Figures 1^11 (overleaf). Diagrammatic representations of chromosome structure through the mitotic cell cycle. Drawings are not to scale. Telophase/G1 . (A) Longitudinal view of a segment of a decondensing chromosome during telophase or a decondensed chromosome during G1. The anaphase chromosome core ...
... Figures 1^11 (overleaf). Diagrammatic representations of chromosome structure through the mitotic cell cycle. Drawings are not to scale. Telophase/G1 . (A) Longitudinal view of a segment of a decondensing chromosome during telophase or a decondensed chromosome during G1. The anaphase chromosome core ...
illuminaHumanv3.db October 28, 2014
... Each manufacturer identifier is mapped to a vector of cytoband locations. The vector length may be one or longer, if there are multiple reported chromosomal locations for a given gene. An NA is reported for any manufacturer identifiers that cannot be mapped to a cytoband at this time. Cytogenetic ba ...
... Each manufacturer identifier is mapped to a vector of cytoband locations. The vector length may be one or longer, if there are multiple reported chromosomal locations for a given gene. An NA is reported for any manufacturer identifiers that cannot be mapped to a cytoband at this time. Cytogenetic ba ...
Whole-transcriptome RNAseq analysis from minute amount of total
... increased the transcript coverage, which has in turn enhanced our ability to detect novel rare transcripts, novel alternative splice isoforms and direct measurement of transcript abundance (3). These technologies are greatly accelerating our understanding of the complexity of gene expression, regula ...
... increased the transcript coverage, which has in turn enhanced our ability to detect novel rare transcripts, novel alternative splice isoforms and direct measurement of transcript abundance (3). These technologies are greatly accelerating our understanding of the complexity of gene expression, regula ...
PDF
... manipulation of paramagnetic beads using a gradient of magnetic field [14]. The two techniques have been developing head to head to achieve nowadays a remarkable level of sophistication. They have their own unique advantages but, largely, offer similar capabilities and require the same workflow. The ...
... manipulation of paramagnetic beads using a gradient of magnetic field [14]. The two techniques have been developing head to head to achieve nowadays a remarkable level of sophistication. They have their own unique advantages but, largely, offer similar capabilities and require the same workflow. The ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.