Solid Tumour Section Soft Tissue Tumors: Low grade fibromyxoid sarcoma
... leukocytes. In fetal tissues, the weakest expression was detected in brain and heart. A splice variant, lacking exon 2, was found in placenta, spleen and fetal liver. Since northern blot analysis was not performed, the possibility of additional splice variants and the actual size of the normal CREB3 ...
... leukocytes. In fetal tissues, the weakest expression was detected in brain and heart. A splice variant, lacking exon 2, was found in placenta, spleen and fetal liver. Since northern blot analysis was not performed, the possibility of additional splice variants and the actual size of the normal CREB3 ...
msc_botnay_pre_pap1_bl2
... Methylation also occurs on arginine and histidine. Similarly, phosphorylation occurs on the hydroxyl group of serine and histidine. Methylation and acetylation remove the positive charge on NH3+, while phosphorylation introduces a negative charge in the form of phosphate group. 3.6 DNA STRUCTURE THE ...
... Methylation also occurs on arginine and histidine. Similarly, phosphorylation occurs on the hydroxyl group of serine and histidine. Methylation and acetylation remove the positive charge on NH3+, while phosphorylation introduces a negative charge in the form of phosphate group. 3.6 DNA STRUCTURE THE ...
Comparison of Deoxyribonucleic Acid Homologies of Six Strains of
... this study were readily distinguished from one another based upon differences in their polynucleotide sequence homologies. The low degrees of homology observed among the three strains of Nitrosomonas europaea suggest that the three morphological types of Nitrosomonas europaea described by Watson and ...
... this study were readily distinguished from one another based upon differences in their polynucleotide sequence homologies. The low degrees of homology observed among the three strains of Nitrosomonas europaea suggest that the three morphological types of Nitrosomonas europaea described by Watson and ...
A Tn 10-lacZ-kanR-URA3 Gene Fusion Transposon for Insertion Mutagenesis and Fusion Analysis of Yeast and Bacterial Genes.
... (1) Transposition events occur in Escherichia coli at high frequency and into many different sites in yeast DNA. It is easy to obtain enough insertions to sensitively define the functional limits of a gene. (2) Transposon insertions can be obtained in a single step by standard transposon procedures ...
... (1) Transposition events occur in Escherichia coli at high frequency and into many different sites in yeast DNA. It is easy to obtain enough insertions to sensitively define the functional limits of a gene. (2) Transposon insertions can be obtained in a single step by standard transposon procedures ...
CSE 181 Project guidelines
... • Some forms of RNA can form secondary structures by “pairing up” with itself. This can have change its properties • Several types exist, classified by function • mRNA – this is what is usually being referred to when a Bioinformatician says “RNA”. This is used to carry a gene’s message out of the nu ...
... • Some forms of RNA can form secondary structures by “pairing up” with itself. This can have change its properties • Several types exist, classified by function • mRNA – this is what is usually being referred to when a Bioinformatician says “RNA”. This is used to carry a gene’s message out of the nu ...
A statistical framework for genome
... because of the inherent noise in gene expression data or population substructure and locus heterogeneity in SNP data. Pathway-based analyses can weaken the negative effects of perturbations not associated with the trait of interest by inferring association from sets of biologically related genes the ...
... because of the inherent noise in gene expression data or population substructure and locus heterogeneity in SNP data. Pathway-based analyses can weaken the negative effects of perturbations not associated with the trait of interest by inferring association from sets of biologically related genes the ...
Cloning and characterisation of a cysteine proteinase gene
... PCR amplification and screening of an amastigote cDNA library. Sequence analysis of the Llacys1 gene showed a high identity to sequence of Leishmania (L.) pifanoi Lpcys1, Leishmania (L.) major cpa, Leishmania (L.) mexicana LCPa, and Leishmania (L.) chagasi Ldccys2. The Llacys1 gene is present in a s ...
... PCR amplification and screening of an amastigote cDNA library. Sequence analysis of the Llacys1 gene showed a high identity to sequence of Leishmania (L.) pifanoi Lpcys1, Leishmania (L.) major cpa, Leishmania (L.) mexicana LCPa, and Leishmania (L.) chagasi Ldccys2. The Llacys1 gene is present in a s ...
The ECF sigma factors of Streptomyces coelicolor A3(2)
... dagA (Buttner et al., 1988). The cloning of the gene encoding S. coelicolor E several years later using a reverse genetics approach revealed that it belonged, together with E. coli E, to a new subfamily of the 70 family (Lonetto et al., 1994). Members of this new subfamily were sufficiently differ ...
... dagA (Buttner et al., 1988). The cloning of the gene encoding S. coelicolor E several years later using a reverse genetics approach revealed that it belonged, together with E. coli E, to a new subfamily of the 70 family (Lonetto et al., 1994). Members of this new subfamily were sufficiently differ ...
GENE NOMENCLATURE OF DIFFERENT TYPES OF SPINOCEREBELLAR ATAXIA (SCA) AND
... has the potential to affect protein function. SIFT is a program that predicts the amino acid substitution affects protein function so that we can prioritize substitutions for the study. We have shown that SIFT can distinguish between functionally neutral and deleterious amino acid changes in mutagen ...
... has the potential to affect protein function. SIFT is a program that predicts the amino acid substitution affects protein function so that we can prioritize substitutions for the study. We have shown that SIFT can distinguish between functionally neutral and deleterious amino acid changes in mutagen ...
Axial homeosis and appendicular skeleton defects in mice with a
... reflect the order of the genes on the chromosome (Dollé et al., 1989, 1991a; Nohno et al., 1991; Izpisúa-Belmonte et al., 1991a,b; Yokouchi et al., 1991; Haack and Gruss, 1993). These 5′ Hox genes express within the developing limb a nested set of transcripts which have been suggested to establish p ...
... reflect the order of the genes on the chromosome (Dollé et al., 1989, 1991a; Nohno et al., 1991; Izpisúa-Belmonte et al., 1991a,b; Yokouchi et al., 1991; Haack and Gruss, 1993). These 5′ Hox genes express within the developing limb a nested set of transcripts which have been suggested to establish p ...
Microbial Ecology
... plant-growth promotion, antagonistic effects against plant pathogens, or biological nitrogen fixation for sustainable agriculture [13]. Although several graminaceous plants have been investigated for the occurrence and diversity of endophytic nitrogen-fixing bacteria, most of them focused on agronom ...
... plant-growth promotion, antagonistic effects against plant pathogens, or biological nitrogen fixation for sustainable agriculture [13]. Although several graminaceous plants have been investigated for the occurrence and diversity of endophytic nitrogen-fixing bacteria, most of them focused on agronom ...
Lectures 12 - 13 Genetics of Human Disease: Hemoglobinopathies
... • Understand the mutations that cause quantitative abnormalities in globin. – Unequal crossing over, and every other possible type of mutation ...
... • Understand the mutations that cause quantitative abnormalities in globin. – Unequal crossing over, and every other possible type of mutation ...
Genetics Review
... This is a characteristic that can be passed from parent to offspring. Trait ...
... This is a characteristic that can be passed from parent to offspring. Trait ...
Clustering approaches for temporal microarray gene expression data
... The template-matching algorithm above does not require researchers to choose a candidate profile because it includes every possible pattern vector as a template profile (compare to Feature-Based Similarity algorithms, which isolate one feature). The downside of this flexibility, however, is that as ...
... The template-matching algorithm above does not require researchers to choose a candidate profile because it includes every possible pattern vector as a template profile (compare to Feature-Based Similarity algorithms, which isolate one feature). The downside of this flexibility, however, is that as ...
Simulating the morphology of barley spike phenotypes using
... the value of M is equal to the sum of all active alleles, multiplied by ten. If G and H exhibit only inactive alleles, M will still adopt a basic value of M0. 2.4.3. Epistasis Figure 1. Simulated barley ears. Three parameters (see Tab. II) were varied while all others were set constant. The ears are ...
... the value of M is equal to the sum of all active alleles, multiplied by ten. If G and H exhibit only inactive alleles, M will still adopt a basic value of M0. 2.4.3. Epistasis Figure 1. Simulated barley ears. Three parameters (see Tab. II) were varied while all others were set constant. The ears are ...
18.11
... and some basic cell-cell interactions Yeast studies have broken new ground in: Tim Hunt Lee Hartwaell Cytoskeleton functions Paul Nurse transcription mechanisms** cell cycle** transcriptional regulation organelle biogenesis chromatin modification secretion* signal transduction Randy W. Schekman prot ...
... and some basic cell-cell interactions Yeast studies have broken new ground in: Tim Hunt Lee Hartwaell Cytoskeleton functions Paul Nurse transcription mechanisms** cell cycle** transcriptional regulation organelle biogenesis chromatin modification secretion* signal transduction Randy W. Schekman prot ...
study
... their predisposition to many diseases, in disease courses, and in drug response [18, 19]. Manifestations of all these differences are likely associated with the biology of sexual reproduction. Sexual dimorphism was suggested to evolve due to differential selection on equally expressed traits that be ...
... their predisposition to many diseases, in disease courses, and in drug response [18, 19]. Manifestations of all these differences are likely associated with the biology of sexual reproduction. Sexual dimorphism was suggested to evolve due to differential selection on equally expressed traits that be ...
Biology Lab
... offspring of organisms have a mixture of both parents’ genes. The offspring receive one set of chromosomes and genes from its mother in the egg and one set from its father in the sperm. This variety allows for natural selection to occur. In this lab, you will simulate meiosis and fertilization and e ...
... offspring of organisms have a mixture of both parents’ genes. The offspring receive one set of chromosomes and genes from its mother in the egg and one set from its father in the sperm. This variety allows for natural selection to occur. In this lab, you will simulate meiosis and fertilization and e ...
Rye SCAR markers for male fertility restoration in the P cytoplasm
... non-restorer genotypes in common rye populations. Identification of new non-restorer lines for the C cytoplasm may be facilitated by using molecular markers. Male sterility/fertility in rye with cytoplasm C is controlled by at least 3 loci, of which the restorer gene Rfc1, located on chromosome 4RL, ...
... non-restorer genotypes in common rye populations. Identification of new non-restorer lines for the C cytoplasm may be facilitated by using molecular markers. Male sterility/fertility in rye with cytoplasm C is controlled by at least 3 loci, of which the restorer gene Rfc1, located on chromosome 4RL, ...
Analysis of Biological Networks: Genetic Interaction Networks
... (Figure 4). This relation defines a network where vertices represent different GO annotations and edges link two GO annotations that are connected by a genetic interaction. The resulting network (Figure 5) contains four highly connected sub-networks, including GO attributes associated with actinbase ...
... (Figure 4). This relation defines a network where vertices represent different GO annotations and edges link two GO annotations that are connected by a genetic interaction. The resulting network (Figure 5) contains four highly connected sub-networks, including GO attributes associated with actinbase ...
Requirements for Driving Antipathogen Effector Genes into
... These are expected to vary according to the target species and molecular construct. To gain insight into the model, we have chosen an exemplar set of parameter values that is consistent with the most extensive published work on mosquitoes (Hammond et al. 2016), hypothetical homozygous fitness costs f ...
... These are expected to vary according to the target species and molecular construct. To gain insight into the model, we have chosen an exemplar set of parameter values that is consistent with the most extensive published work on mosquitoes (Hammond et al. 2016), hypothetical homozygous fitness costs f ...
Practice test answers
... a. 0 percent c. 50 percent b. 25 percent d. 100 percent ANSWER: C 3. Colorblindness is more common in males than in females because a. fathers pass the allele for colorblindness to their sons only. b. the allele for colorblindness is located on the Y chromosome. c. the allele for colorblindness is r ...
... a. 0 percent c. 50 percent b. 25 percent d. 100 percent ANSWER: C 3. Colorblindness is more common in males than in females because a. fathers pass the allele for colorblindness to their sons only. b. the allele for colorblindness is located on the Y chromosome. c. the allele for colorblindness is r ...
Validated preCRMs
... following two criteria were predicted to be CRMs: (1) the RP score is greater than 0 and (2) the alignment contains a predicted match to a binding site for GATA-1. Only noncoding DNA sequences were used. The RP scores were determined using the phylogeny-based method of Taylor et al. (2006) on TBA al ...
... following two criteria were predicted to be CRMs: (1) the RP score is greater than 0 and (2) the alignment contains a predicted match to a binding site for GATA-1. Only noncoding DNA sequences were used. The RP scores were determined using the phylogeny-based method of Taylor et al. (2006) on TBA al ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.