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Solving Multiple Sequence Alignment Problems using Various E
Solving Multiple Sequence Alignment Problems using Various E

... sequence). However, this is based on the assumption that the combined monomers evenly spaced along the single dimension of the molecule's primary structure. From now on, we will refer to an alignment of two DNA sequences. Every element in a trace is either a match or a gap. Where a residue in one of ...
tRNA & Ribosomes
tRNA & Ribosomes

... Base pairing over extended stretches of complementary base sequences in two nucleic acid strands stabilizes secondary structure, such as the double helix of DNA. Stacking interactions between adjacent hydrophobic bases contribute to stabilization of such secondary structures. Each base interacts wit ...
plantcell.org - Schnable Lab
plantcell.org - Schnable Lab

... from companion cells labeled by the expression of green fluorescent protein (Brandt et al., 1999). However, a disadvantage of this method is that it requires the use of cell-specific promoters, and relatively few such promoters are available. A second way to collect specific cell types is to use pro ...
Solid Tumour Section Mesothelioma: t(14;22)(q32;q12) in mesothelioma Atlas of Genetics and Cytogenetics
Solid Tumour Section Mesothelioma: t(14;22)(q32;q12) in mesothelioma Atlas of Genetics and Cytogenetics

... number NM_013986 version 3; former exon 7 in sequence with accession number X66899) is fused to exon 2 of YY1 (nucleotide 1160 accession number NM_003403 version 3). The putative EWSR1-YY1 protein would contain the transactivation domain of EWSR1 and the DNA binding domain of YY1 and thus may act as ...
Concept_Paper
Concept_Paper

... advantages for protein coding sequence cloning, sequencing and gene prediction:  The A+T composition of the coding sequence (~65%) [36] is within the range of previously sequenced genomes (see below) and is distinct from that of non-coding sequences, including intergenic regions, untranslated trans ...
Document
Document

... involved in their pathogenicity and the discovery of effective ways to control or cure phytoplasma diseases. Analysis of the phytoplasma genome suggests reductive evolution as a consequence of its life as an intracellular parasite in a nutrient-rich environment and shows that phytoplasma lacks sever ...
C-Collate3 740..903
C-Collate3 740..903

... and readily accessed within seconds, and neatly so that at other times the 46 chromosomes can be easily removed from the boat. With this perspective, the mechanisms by which DNA is organized within the cell nucleus now appear impressive and complex. Abundant, structural chromosomal proteins must bin ...
Chapter 13 – Meiosis and Sexual Life Cycles
Chapter 13 – Meiosis and Sexual Life Cycles

... Genes are segments of DNA. Genetic information is transmitted as specific sequences of the four deoxyribonucleotides in DNA. ...
Full text in pdf - International Microbiology
Full text in pdf - International Microbiology

... no significant identity match with phosphorylating GAPDHs. Both non-phosphorylating GAPDH and phosphorylating GAPDHs showed high specificity towards D-glyceraldehyde3-phosphate [13,18], which suggested that substrate specificity of the two GAPDH forms emerged by convergent evolution along independen ...
Developmental Psychobiology - Champagne Lab
Developmental Psychobiology - Champagne Lab

... Developmental Psychobiology ...
Recombinant DNA Lesson - Ms. Guiotto Biology Class
Recombinant DNA Lesson - Ms. Guiotto Biology Class

... placed in a solution containing a ligase, recombination occurs at random. Many recombinations are possible, and a fraction of these contain the desired recombinant DNA. For example, if one of the fragments with complementary ends was a ...
Chapter 2 Patterns of Inheritance Chapter 2 Patterns of Inheritance
Chapter 2 Patterns of Inheritance Chapter 2 Patterns of Inheritance

... two years to make sure that they were pure. A pure line is a population that breeds true for (shows no variation in) the particular character being studied; that is, all offspring produced by selfing or crossing within the population are identical for this character. By making sure that his lines br ...
Indinavir inhibits sterol-regulatory element-binding protein
Indinavir inhibits sterol-regulatory element-binding protein

... increases the risk of cardiovascular complications [5,6]. Recent studies revealed that HAART-related adverse effects are common and persist in patients remaining on ...
The Gene Gateway Workbook
The Gene Gateway Workbook

... of the protein product are available in Protein Data Bank (PDB), the international repository for macromolecular structure data. ...
sacB - GENI
sacB - GENI

... The modular format allows testing completely different genes every semester but does so with repetitive sets of protocols and materials Consistency makes it possible for busy faculty to perform actual research in the classroom without having to prepare de novo labs every semester ...
Chromosomal Microarray (CGH+SNP)
Chromosomal Microarray (CGH+SNP)

... What is Chromosomal Microarray? Chromosomal Microarray evaluates DNA copy number (by comparative genomic hybridization, or CGH) across the genome at higher resolution than routine chromosome analysis.  It can detect submicroscopic genomic imbalances not detectable by routine chromosome analysis, as ...
Class notes on epistasis and GWAI analysis
Class notes on epistasis and GWAI analysis

... It is a way of identifying patterns in data, and expressing the data in such a way as to highlight their similarities and differences. PCA allows data transformation to a new coordinate system such that the projection of the data along the first new coordinate has the largest variance; the second pr ...
Patterns of prokaryotic lateral gene transfers affecting parasitic
Patterns of prokaryotic lateral gene transfers affecting parasitic

... Full list of author information is available at the end of the article ...
Patterns of prokaryotic lateral gene transfers affecting parasitic
Patterns of prokaryotic lateral gene transfers affecting parasitic

... Full list of author information is available at the end of the article ...
Real World Genetics - South Kingstown High School
Real World Genetics - South Kingstown High School

... each trait. One allele comes from each parent. This means, that during the formation of each gamete (egg and sperm), the two alleles must separate or segregate from each other. Each gamete only carries a single gene (allele). • Fourth Conclusion: Principle of Independent Assortment - genes for diffe ...
msc_botnay_pre_pap1_bl2
msc_botnay_pre_pap1_bl2

... Methylation also occurs on arginine and histidine. Similarly, phosphorylation occurs on the hydroxyl group of serine and histidine. Methylation and acetylation remove the positive charge on NH3+, while phosphorylation introduces a negative charge in the form of phosphate group. 3.6 DNA STRUCTURE THE ...
Comparison of Deoxyribonucleic Acid Homologies of Six Strains of
Comparison of Deoxyribonucleic Acid Homologies of Six Strains of

... this study were readily distinguished from one another based upon differences in their polynucleotide sequence homologies. The low degrees of homology observed among the three strains of Nitrosomonas europaea suggest that the three morphological types of Nitrosomonas europaea described by Watson and ...
Nuclear Gene Trees and the Phylogenetic Relationships of the
Nuclear Gene Trees and the Phylogenetic Relationships of the

... humans, IRBP falls on chromosome 10 (region 10p12). A 514-bp region of the a 1,3 GT gene was also sequenced which maps to chromosome 9 (region 9q33– q34) in humans. This gene is functional in most mammals but is apparently inactive in all catarrhines, Old World monkeys, and apes. This sequence overl ...
Pre-AP Biology
Pre-AP Biology

... What is spontaneous generation? Explain how the 4 major scientists disproved spontaneous generation. ...
Solid Tumour Section Soft Tissue Tumors: Low grade fibromyxoid sarcoma
Solid Tumour Section Soft Tissue Tumors: Low grade fibromyxoid sarcoma

... leukocytes. In fetal tissues, the weakest expression was detected in brain and heart. A splice variant, lacking exon 2, was found in placenta, spleen and fetal liver. Since northern blot analysis was not performed, the possibility of additional splice variants and the actual size of the normal CREB3 ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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