RNA PROCESSING AND RNPs
... Some pre-mRNAs contain more than one poly(A) site and these may be used under different circumstances to generate different mature mRNAs. In one cell the stronger poly(A) site is used by default, but in other cell a factor may prevent stronger site from being used. ...
... Some pre-mRNAs contain more than one poly(A) site and these may be used under different circumstances to generate different mature mRNAs. In one cell the stronger poly(A) site is used by default, but in other cell a factor may prevent stronger site from being used. ...
A Resurrection of B Chromosomes?
... How are genes of interest introduced onto engineered minichromosomes? Targeted transgene integration into unique chromosomal loci might be achieved using gene constructs in combination with a site-specific recombinase cassette as provided by the Cre/lox system. The proof of principle has been demons ...
... How are genes of interest introduced onto engineered minichromosomes? Targeted transgene integration into unique chromosomal loci might be achieved using gene constructs in combination with a site-specific recombinase cassette as provided by the Cre/lox system. The proof of principle has been demons ...
General
... KEGG does not predict presence or absence of pathways KEGG lacks pathway hole filler, operon predictor Curation tools KEGG does not distribute curation tools No ability to customize pathways to the organism Pathway Tools schema much more comprehensive Visualization and analysis KEGG ...
... KEGG does not predict presence or absence of pathways KEGG lacks pathway hole filler, operon predictor Curation tools KEGG does not distribute curation tools No ability to customize pathways to the organism Pathway Tools schema much more comprehensive Visualization and analysis KEGG ...
Gentile, Margaret: Computational Methods for the Design of PCR Primers for the Amplification of functional Markers from Environmental Samples
... In previous methods for primer design for amplification of functional markers, global alignment methods were used for sequence alignment (Braker et al., 1998 and Hallin and Lindgren, 1999). For example, the MULTIALIGN algorithm used by Braker et al. is a global algorithm which seeks to make the best ...
... In previous methods for primer design for amplification of functional markers, global alignment methods were used for sequence alignment (Braker et al., 1998 and Hallin and Lindgren, 1999). For example, the MULTIALIGN algorithm used by Braker et al. is a global algorithm which seeks to make the best ...
Genetics of Asthma – Paul E. Moore MD
... specific polymorphisms in candidate genes and certain disease characteristics. • To date, close to 200 candidate genes in over 500 published studies have been linked to different asthma phenotypes. ...
... specific polymorphisms in candidate genes and certain disease characteristics. • To date, close to 200 candidate genes in over 500 published studies have been linked to different asthma phenotypes. ...
DNA Profiling
... DNA is loaded into an agarose gel slab, placed into a chamber filled with a conductive buffer solution Direct current is passed between wire electrodes at each end of the chamber DNA is negatively charged, so drawn toward positive pole (anode) when placed in an electric field Matrix of gel acts as a ...
... DNA is loaded into an agarose gel slab, placed into a chamber filled with a conductive buffer solution Direct current is passed between wire electrodes at each end of the chamber DNA is negatively charged, so drawn toward positive pole (anode) when placed in an electric field Matrix of gel acts as a ...
Keystone Review - demascalchemistry
... Explain the functional relationships between DNA, genes, alleles, and chromosomes and their roles in inheritance. ...
... Explain the functional relationships between DNA, genes, alleles, and chromosomes and their roles in inheritance. ...
R i
... (400 bp each): the mean Ri values for sites in 138 promoters on the transcribed strand and 137 on the antisense strand had sites exceeding threshold. 37% of the genes on chromosome 21 would be NF-kB targets!! Also, multiple weak binding sites with low Ri values can falsely exclude genes containing s ...
... (400 bp each): the mean Ri values for sites in 138 promoters on the transcribed strand and 137 on the antisense strand had sites exceeding threshold. 37% of the genes on chromosome 21 would be NF-kB targets!! Also, multiple weak binding sites with low Ri values can falsely exclude genes containing s ...
6.3 Mendel and Heredity
... Mendel laid the groundwork for genetics. • Traits are distinguishing characteristics that are inherited. (eye color, hair color) • Genetics is the study of biological inheritance patterns and variation. • Gregor Mendel showed that traits are inherited as discrete units. – Like different colored marb ...
... Mendel laid the groundwork for genetics. • Traits are distinguishing characteristics that are inherited. (eye color, hair color) • Genetics is the study of biological inheritance patterns and variation. • Gregor Mendel showed that traits are inherited as discrete units. – Like different colored marb ...
aabb
... information essential to life processes. • Mendel was able to describe a model of inheritance of traits, and his work represents an application of mathematical reasoning to a biological problem. • However, most traits result from interactions of many genes and do not follow Mendelian patterns of inh ...
... information essential to life processes. • Mendel was able to describe a model of inheritance of traits, and his work represents an application of mathematical reasoning to a biological problem. • However, most traits result from interactions of many genes and do not follow Mendelian patterns of inh ...
Genetic Inheritance in Humans | Principles of Biology from Nature
... The human genome contains ~21,000 genes that encode proteins. Each gene sits in a specific location on a chromosome. Humans have 22 pairs of autosomes and one pair of sex chromosomes (XX for females and XY for males). Clinical cytogeneticists are scientists who study chromosomes and detect and analy ...
... The human genome contains ~21,000 genes that encode proteins. Each gene sits in a specific location on a chromosome. Humans have 22 pairs of autosomes and one pair of sex chromosomes (XX for females and XY for males). Clinical cytogeneticists are scientists who study chromosomes and detect and analy ...
Bio 102 Practice Problems Mendelian Genetics: Beyond Pea Plants
... of digestive enzymes. These different symptoms (phenotypes) could result from defects in two individual genes, or they could be different effects of a defect in one gene. It is difficult to get enough offspring from humans of known genotypes to study a problem such as this genetically, but mice also ...
... of digestive enzymes. These different symptoms (phenotypes) could result from defects in two individual genes, or they could be different effects of a defect in one gene. It is difficult to get enough offspring from humans of known genotypes to study a problem such as this genetically, but mice also ...
Earlobes Article
... 1. If you got a dominant, free lobe allele (we will label that E) from your father and a dominant, free lobe allele from your mother (E), then you have (EE), two dominant, free lobe alleles, so your ears will have free lobes. 2. If you got a recessive, attached lobe allele from your father (we will ...
... 1. If you got a dominant, free lobe allele (we will label that E) from your father and a dominant, free lobe allele from your mother (E), then you have (EE), two dominant, free lobe alleles, so your ears will have free lobes. 2. If you got a recessive, attached lobe allele from your father (we will ...
Genetic causes of male and female infertility
... Research on genetic causes of male and female infertility rapidly expanded in the last years, following the development of in vitro fertilization techniques. Genetic tests are available to explore the cause of the infertility and assess the risk of a given couple to ...
... Research on genetic causes of male and female infertility rapidly expanded in the last years, following the development of in vitro fertilization techniques. Genetic tests are available to explore the cause of the infertility and assess the risk of a given couple to ...
Vectors for expression and modification of cDNA sequences in
... University) as a 0.7 kb BamHI fragment into the unique BamHI of pGEMQa-2P to form an intermediate plasmid, pMYX1. In order to provide a selectable marker for use in N. crassa the benomyl resistant -tubulin gene of pSV50 (Orbach et al. 1986. Mol. Cell. Biol. 6:2452-2461) was inserted into the unique ...
... University) as a 0.7 kb BamHI fragment into the unique BamHI of pGEMQa-2P to form an intermediate plasmid, pMYX1. In order to provide a selectable marker for use in N. crassa the benomyl resistant -tubulin gene of pSV50 (Orbach et al. 1986. Mol. Cell. Biol. 6:2452-2461) was inserted into the unique ...
Identification and quantification of mycotoxigenic fungi
... metabolites are being considered [47]. The levels of detection for mycotoxins are extremely sensitive and now concentrations of as low as 1015 (106 is the mg kg1 level) can be conceived of with NMR and mass spectroscopy. Furthermore, it is possible to determine if all the genes of a pathway can b ...
... metabolites are being considered [47]. The levels of detection for mycotoxins are extremely sensitive and now concentrations of as low as 1015 (106 is the mg kg1 level) can be conceived of with NMR and mass spectroscopy. Furthermore, it is possible to determine if all the genes of a pathway can b ...
SF 106 year 1 report 2010
... The aim of this work is to develop robust assisted breeding and selection tools that will enable breeders to accelerate new variety development with extended shelf-life and thus reduce fruit spoilage and waste in the supply chain. No exploitation plans can be drawn up at this early stage of the proj ...
... The aim of this work is to develop robust assisted breeding and selection tools that will enable breeders to accelerate new variety development with extended shelf-life and thus reduce fruit spoilage and waste in the supply chain. No exploitation plans can be drawn up at this early stage of the proj ...
Comparative genomics exercises - Genome curation on emerging
... Choose ‘Hidden’ from the drop-down box for A. oryzae (pink), A. nidulans (brown) and A. terreus (red). Choose ‘1 (reference)’ for A. fumigatus (purple). Choose ‘2’ for N. fischeri (green) and ‘3’ for A. clavatus (yellow). Click ‘redraw’. * To expand the range on either side of the reference cluster, ...
... Choose ‘Hidden’ from the drop-down box for A. oryzae (pink), A. nidulans (brown) and A. terreus (red). Choose ‘1 (reference)’ for A. fumigatus (purple). Choose ‘2’ for N. fischeri (green) and ‘3’ for A. clavatus (yellow). Click ‘redraw’. * To expand the range on either side of the reference cluster, ...
DNA Mismatch Repair and Synonymous Codon Evolution in
... codon use between mammalian genes within a genome are due to differences in the efficiency of DNA mismatch repair. This hypothesis was tested by developing a model of mismatch repair, which was used to predict the expected relationship between the rate of substitution and G+C content at silent sites ...
... codon use between mammalian genes within a genome are due to differences in the efficiency of DNA mismatch repair. This hypothesis was tested by developing a model of mismatch repair, which was used to predict the expected relationship between the rate of substitution and G+C content at silent sites ...
Problems in Mendelian Genetics
... In Drosophila (fruit flies), the wild type eye color, brick red, is actually produced by the deposition of two pigments in the eyes, a dull brown pigment and a brilliant red pigment. These two pigments are produced by the action of two different, non-allelic (and non-linked) genes. Each of these gen ...
... In Drosophila (fruit flies), the wild type eye color, brick red, is actually produced by the deposition of two pigments in the eyes, a dull brown pigment and a brilliant red pigment. These two pigments are produced by the action of two different, non-allelic (and non-linked) genes. Each of these gen ...
Problems in Mendelian Genetics
... In Drosophila (fruit flies), the wild type eye color, brick red, is actually produced by the deposition of two pigments in the eyes, a dull brown pigment and a brilliant red pigment. These two pigments are produced by the action of two different, non-allelic (and non-linked) genes. Each of these gen ...
... In Drosophila (fruit flies), the wild type eye color, brick red, is actually produced by the deposition of two pigments in the eyes, a dull brown pigment and a brilliant red pigment. These two pigments are produced by the action of two different, non-allelic (and non-linked) genes. Each of these gen ...
Problems in Mendelian Genetics
... In Drosophila (fruit flies), the wild type eye color, brick red, is actually produced by the deposition of two pigments in the eyes, a dull brown pigment and a brilliant red pigment. These two pigments are produced by the action of two different, non-allelic (and non-linked) genes. Each of these gen ...
... In Drosophila (fruit flies), the wild type eye color, brick red, is actually produced by the deposition of two pigments in the eyes, a dull brown pigment and a brilliant red pigment. These two pigments are produced by the action of two different, non-allelic (and non-linked) genes. Each of these gen ...
Supplementary Table S1: Published information about
... At least three of the dorsal group genes (snake, easter and gastrulation defective) encode secreted serine proteases, which probably function during early development in the perivitelline compartment of the embryo. The results indicate that the three proteases function in a sequential activation cas ...
... At least three of the dorsal group genes (snake, easter and gastrulation defective) encode secreted serine proteases, which probably function during early development in the perivitelline compartment of the embryo. The results indicate that the three proteases function in a sequential activation cas ...
The evolutionary mechanics of bacterial protein toxins
... This is passing of genetic material from parent cell to daughter cells through simple mitosis. Both daughter cells produced in mitosis are identical clones of the parent cell. Horizontal gene transfer This is passing of genetic material from one cell to another unrelated one. Sometimes the cel ...
... This is passing of genetic material from parent cell to daughter cells through simple mitosis. Both daughter cells produced in mitosis are identical clones of the parent cell. Horizontal gene transfer This is passing of genetic material from one cell to another unrelated one. Sometimes the cel ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.