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CRS questions
CRS questions

... results of this type of experiment. ...
Leukaemia Section 3q27 rearrangements in non Hodgkin lymphoma,
Leukaemia Section 3q27 rearrangements in non Hodgkin lymphoma,

... in the REAL classification; very rare cases were also reported with mantle cell lymphoma and chronic lymphocytic leukemia. 3q27 breaks are usually, but not invariably, associated with rearrangements of the BCL6 gene located at the 3q27 chromosome band; likewise rearrangements of this gene may occur ...
MEDICAL BIOLOGY
MEDICAL BIOLOGY

... the individuals give several sorts of gametes (2 ) Genotype - refers to the sum total of genes inherited from both the parents which provides individual development (ontogenesis) and formation of phenotype. Phenotype – refers to the detectable or observable structural and functional characters by th ...
Divergent Evolution of Duplicate Genes Leads to Genetic
Divergent Evolution of Duplicate Genes Leads to Genetic

... thaliana, loci interact epistatically, controlling a recessive embryo lethality. This interaction is explained by divergent evolution occurring among paralogs of an essential duplicate gene, for which the functional copy is not located at the same locus in different accessions. These paralogs demons ...
Wide-spread polyploidizations during plant evolution Dicot
Wide-spread polyploidizations during plant evolution Dicot

... Figure 3. Progression of rearrangem ent s and chromoso me fusions leading t o t he loss of a cent romere in Z. rouxii. Two non-reciprocal telomeric translocations and a telomere-to-telomere fusion gave rise to the extant chromosome structures in Z. rouxii. Chromosomes in green boxes are those that u ...
General background text Pharmacogenetics - CYP3A4
General background text Pharmacogenetics - CYP3A4

... the functionality of a protein (for example the enzyme or the receptor), but also the physical manifestation of a disease. The phenotype is a result of the genotype that a person possesses, the degree of expression of the gene in question and the combination with environmental factors such as co-med ...
Genetically Essential and Nonessential a-Tubulin Genes Specify Functionally Interchangeable Proteins.
Genetically Essential and Nonessential a-Tubulin Genes Specify Functionally Interchangeable Proteins.

... Both a-tubulin genes map to chromosome 13. Some of the most extensively studied gene families in higher organisms, such as histones and globins, are clustered. In yeast, linkage of related genes occurs only occasionally (e.g., the genes involved in galactose metabolism). Both TUB] and TUB3 were mapp ...
uniprotkb-goa_aug2011
uniprotkb-goa_aug2011

... • Most popular type of GO analysis • Determines which GO terms are more often associated with a specified list of genes/proteins compared with a control list or rest of genome • Many tools available to do this analysis • User must decide which is best for their analysis ...
Quantitative Genetics
Quantitative Genetics

... Multiple-factor hypothesis: many genes produce additive effect. Polygenes: factors with small, equal effect Polygenic traits: influenced by genetic variation at many loci - analysis cannot be done by simple Mendelian genetics - must compare phenotypic expression in close relatives (known to share a ...
Biology Pre-Learning Check
Biology Pre-Learning Check

... 2. _____ something that has more than one gene controlling it 3. _____ different form of a gene 4. _____ genetic cross where two traits are examined at once 5. _____ one allele does not completely suppress the other, the phenotypes mix 6. _____ chromosomes line up randomly during meiosis, thus genes ...
A. niger
A. niger

... Metabolism: The chemical processes occurring within a living cell or organism that are necessary for the maintenance of life. In metabolism some substances are broken down to yield energy for vital processes while other substances, necessary for life, are synthesized. ...
C h e m g u id e   –... DNA:  PROTEIN SYNTHESIS
C h e m g u id e –... DNA: PROTEIN SYNTHESIS

... 1. a) The tRNA molecule has to attach to the mRNA molecule where the mRNA has the code for methionine. In order for that to happen, the sequence of bases at the bottom of the tRNA molecule must be exactly complementary to those in the mRNA. The mRNA code for methionine is AUG. The anti-codon UAC wil ...
Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular
Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular

... mRNAs have had one of two splice-leader sequences transspliced onto the 5 end of the message (Fig. C.3). PremRNAs do not contain these splice-leader sequences, but during processing in the nucleus, they are trans-spliced to acceptor sites near the 5 ends of the corresponding primary transcripts. T ...
Candidatus Paenicardinium endonii
Candidatus Paenicardinium endonii

... (Atibalentja et al., 2004). Both DNA strands were sequenced from each of three and four clones, respectively, for the 16S rRNA and gyrB genes, and the resulting DNA fragments were assembled with the computer program SEQUENCHER (Gene Codes). Phylogenetic analysis. The consensus DNA sequences for the ...
File
File

... red eye color. When two pure-breeding red strains 1 and 2 are intercrossed, the F1 is also red. However when the F1 is backcrossed to strain 1, the progeny show 3/4 red and 1/4 peach flies. The genotype of the strain 1 must have been A) p+/p+ ; s+/s+ B) p+/p ; s/s C) p/p ; s+/s+ D) p+/p ; s+/s * E) ...
Alzheimer`s Disease Genetics Fact Sheet
Alzheimer`s Disease Genetics Fact Sheet

... our 23 pairs of chromosomes. A chromosome is a thread-like structure found in the cell’s nucleus, which can carry hundreds, sometimes thousands, of genes. In humans, one of each pair of 23 chromosomes is inherited from each parent. The genetic material on these chromosomes is collectively referred t ...
2.3 Bombardment of detached potato leaves and confocal
2.3 Bombardment of detached potato leaves and confocal

... the virus, probably by interacting with plasmodesmata [20,21]. At this stage we do not know whether these two different functions are inter-related. It is also possible that Nb, like other resistance genes, is part of a surveillance system for detection of foreign molecules in plant cells [22]. Anal ...
Inheritance of Aldehyde Oxidase in Drosophila melanogaster
Inheritance of Aldehyde Oxidase in Drosophila melanogaster

... The haploid (N) number of chromosomes is 4 and the chromosomes are designated X(1), 2, 3, and 4. The 2, 3, and 4 chromosomes are the same in both sexes and are referred to as autosomes to distinguish them from the X and Y sex chromosomes. Female Drosophila are characterized by having two X chromosom ...
Bioinformatics Database Worksheet
Bioinformatics Database Worksheet

... (for blue, green, and red light detection). Four hits look like visual pigments, which probably does not surprise you. To the left of each entry is the chromosome number, allowing you to tell which red mark corresponds to each entry. Note that several hits are on the X chromosome, one of the sex-det ...
sl revision notes on theoretical genetics
sl revision notes on theoretical genetics

... IA allele codes for an enzyme that puts A carbohydrate on surface of blood cells. IB allele codes for an enzyme that puts B carbohydrate on surface of blood cells. i allele codes for neither carbohydrate (recessive to IA and IB alleles). ...
Genomic Consequences of Background Effects on scalloped Mutant
Genomic Consequences of Background Effects on scalloped Mutant

... Genetic background effects contribute to the phenotypic consequences of mutations and are pervasive across all domains of life that have been examined, yet little is known about how they modify genetic systems. In part this is due to the lack of tractable model systems that have been explicitly deve ...
Section F
Section F

... • Definition: This process involves the exchange of homologous regions between two DNA molecules, it is also known as postreplication repair. The integrity of DNA containing un-repaired lesions can be fixed during replication by homologous recombination. • Mechanism: 1. In eukaryotes, this commonly ...
GENES AND SPECIATION
GENES AND SPECIATION

... existence? These questions are some of the most enduring in biology and remain controversial today. Under many commonly accepted species definitions, speciation can be viewed as the process by which two identical populations diverge genetically to the point at which their subsequent merger would not ...
Transcription and Translation RNA
Transcription and Translation RNA

... in the range of 73 - 93 nucleotides) that participate in the translation of mRNAs. They are not part of the ribosome. But like rRNA they have extensive secondary structure produced by intramolecular base pairing between nucleotides. tRNAs are unique in that they contain many highly modified and unus ...
Genetic manipulation and quantitative
Genetic manipulation and quantitative

... of DNA array and proteome analyses as post-genomics tools in Arabidopsis and green algae. A number of QTL analyses using interspecific crosses have been conducted to identify the loci anduor genes controlling physiological traits in various crop plants including tomato (Frary et al., 2000) and maize ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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