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Genetic manipulation and quantitative
Genetic manipulation and quantitative

... of DNA array and proteome analyses as post-genomics tools in Arabidopsis and green algae. A number of QTL analyses using interspecific crosses have been conducted to identify the loci anduor genes controlling physiological traits in various crop plants including tomato (Frary et al., 2000) and maize ...
Ch 14 summary - OHS General Biology
Ch 14 summary - OHS General Biology

... We can use the addition rule to determine the probability that an F2 plant from a monohybrid cross will be heterozygous rather than homozygous. o The probability of an event that can occur in two or more mutually exclusive ways is the sum of the individual probabilities of those ways. o The probabil ...
I. Problems Involving One Gene
I. Problems Involving One Gene

... lovely orange hair on his snout. He and his mate, OrgggWny, have six offspring, three boys and three girls. Please answer the following questions about this family. How many of MyxRotcccc’s and OrgggWny’s offspring have hairy snouts? Can you predict which ones? Their eldest son, Bob, marries and has ...
GENES AND SPECIATION
GENES AND SPECIATION

... existence? These questions are some of the most enduring in biology and remain controversial today. Under many commonly accepted species definitions, speciation can be viewed as the process by which two identical populations diverge genetically to the point at which their subsequent merger would not ...
Recent progress on the Ada response for inducible repair of DNA
Recent progress on the Ada response for inducible repair of DNA

... adaptive response in other microorganisms. Furthermore, certain algae and fungi growing in saline environments generate MeCl as a product of chloride detoxification (Sedgwick and Vaughan, 1991). MeCl is probably the most abundant methylating agent in our environment (Crutzen and Andreae, 1990). Chem ...
Genomic Consequences of Background Effects on scalloped Mutant
Genomic Consequences of Background Effects on scalloped Mutant

... Genetic background effects contribute to the phenotypic consequences of mutations and are pervasive across all domains of life that have been examined, yet little is known about how they modify genetic systems. In part this is due to the lack of tractable model systems that have been explicitly deve ...
The Genetics of Beta-galactosidase
The Genetics of Beta-galactosidase

... of enzymes earlier in the pathway. If one thinks about the process of synthesizing a protein, there are several steps, from transcription to translation to the final folding and processing of the protein. Regulation can occur (and has been shown to occur) at any of these steps. Beta-Galactosidase an ...
Transcription and Translation RNA
Transcription and Translation RNA

... in the range of 73 - 93 nucleotides) that participate in the translation of mRNAs. They are not part of the ribosome. But like rRNA they have extensive secondary structure produced by intramolecular base pairing between nucleotides. tRNAs are unique in that they contain many highly modified and unus ...
A single-nucleotide polymorphism tagging set for human drug
A single-nucleotide polymorphism tagging set for human drug

... Carlson, C.S. et al. Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am. J. Hum. Genet. 74, 106−120 (2004). ...
Module 7 – Microbial Molecular Biology and Genetics
Module 7 – Microbial Molecular Biology and Genetics

... Each nucleotide in RNA contains a ribose sugar, with carbons numbered 1' through 5'. A base is attached to the 1' position, in general, adenine (A), cytosine (C), guanine (G), or uracil (U). Adenine and guanine are purines, cytosine, and uracil are pyrimidines. A phosphate group is attached to the 3 ...
Bitter-Tasting Ability
Bitter-Tasting Ability

... a genetic basis to taste. Arthur Fox had synthesized some phenylthiocarbamide (PTC), and some of the PTC dust escaped into the air as he was transferring it into a bottle. Lab-mate C.R. Noller complained that the dust had a bitter taste, but Fox tasted nothing—even when he directly sampled the cryst ...
Interplay between copy number, dosage compensation and
Interplay between copy number, dosage compensation and

... In contrast to work with single cell organisms, the impact of gene dosage on expression variability in metazoans is less well studied. However, a full understanding of the effect of gene copy deletions is fundamental for better understanding of diseases that originate from gene copy number changes. ...
PowerPoint
PowerPoint

... Demographic factors can also cause these departures from neutral expectations! Too many young alleles -> recent population expansion Too many old alleles -> population substructure Thus, there is a composite alternative hypothesis, so that rejection of the null does not imply selection. Rather, sele ...
File
File

... The population of a species shows genetic varation. Knowing this makes it difficult to be specific about how a population will respond to a change in their environment. Therefore biology requires a 'population thinking' approach so that phenomena might be understood. This is what distinguishes Biolo ...
Clinical Laboratory Reports in Molecular Pathology
Clinical Laboratory Reports in Molecular Pathology

... subject to false-positive or false-negative results, thus imparting a probabilistic risk of disease rather than an absolute answer. Depending on the performance characteristics of each assay and the clinical impact of an incorrect result, it is worth describing these limitations in the report. Thus, ...
Ledbetter Presentation 8/15/05
Ledbetter Presentation 8/15/05

... to gene discovery and molecular karyotype August, 2005 David H. Ledbetter, Ph.D. Department of Human Genetics Emory University [email protected] ...
Maternal plasma folate during pregnancy impacts differential DNA
Maternal plasma folate during pregnancy impacts differential DNA

... • Robust linear models – Adjusted for confounders, batch effect and cell count estimations ...
Neutral and Non-Neutral Evolution of Duplicated Genes with Gene
Neutral and Non-Neutral Evolution of Duplicated Genes with Gene

... protein sequence identity [35]. In order to explain these observations, they proposed the following hypothesis. According to their hypothesis, the ribosomal duplicates have subfunctionalized at the expression level due to mutations in the regulatory non-coding regions. Nevertheless, there is still v ...
PowerPoint 演示文稿 - Xiamen University
PowerPoint 演示文稿 - Xiamen University

... produces repressor (green), which binds to the operator and blocks RNA polymerase from entering the/ac structural genes. Instead, the polymerase spends its time making extremely short RNA, no mere than six nucleotides long. (b) Presence of lactose, derepression. The inducer (black) binds to represso ...
Biology 22 Problem Set 1 Spring 2003
Biology 22 Problem Set 1 Spring 2003

... a. What are the genotypes of the original parents in this cross? Write each genotype to show which alleles are linked together on the same chromosome. b. What are the genotypes of the F1 males and females? Write each genotype to show which alleles are linked together on the same chromosome. c. Draw ...
Mycorrhiza
Mycorrhiza

... putative tomato sugar transporter, was isolated from mycorrhizal roots by using a PCR-based approach. Based on sequence similarity, conserved motifs and predicted membrane topology, LeST3 was classified as a putative monosaccharide transporter of the sugar transporter subgroup of the major facilitat ...
Chapter 29 PowerPoint
Chapter 29 PowerPoint

... Copyright © 2010 Pearson Education, Inc. ...
Slide 1
Slide 1

... dominant allele are required to see the full phenotype; heterozygote phenotype is intermediate to the homozygotes (e.g., flower color in snapdragons) Flower color in snapdragons ...
Overview of Genetics
Overview of Genetics

... body contain the same genetic information  Differentiation causes cells to differ in appearance and function. This is controlled by variation in gene expression.  Stem cells are less specialized ...
LacI_Biochem.ppt
LacI_Biochem.ppt

... in the right orientation with respect to the inverted repeat ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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