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Lecture 1: Molecular Biology
Lecture 1: Molecular Biology

... Human Chromosome Banding Patterns ...
Gregor Mendel
Gregor Mendel

... • homo- = like (homologous: like chromosomes that form a pair) ...
Document
Document

... transfer RNA Small, ~80 nucleotides long. tRNA exists as a single-stranded molecule. However, regions of double helix can form where there is some base pair complementation (U and A , G and C), resulting in hairpin loops. The RNA molecule with its hairpin loops is said to have a secondary structure ...
Chapter 17 - TeacherWeb
Chapter 17 - TeacherWeb

... transfer RNA Small, ~80 nucleotides long. tRNA exists as a single-stranded molecule. However, regions of double helix can form where there is some base pair complementation (U and A , G and C), resulting in hairpin loops. The RNA molecule with its hairpin loops is said to have a secondary structure ...
chapt16_lecture_edited [Compatibility Mode]
chapt16_lecture_edited [Compatibility Mode]

... At meiosis, one member of each chromosome pair segregates into one daughter nucleus and its homologue segregates into the other daughter nucleus. Each of the resulting haploid cells contains only one set of chromosomes. During the formation of haploid cells, the members of different chromosome pairs ...
sex
sex

... TRANSLOCATION: breaks off a segment from one chromosome and attaches it to another gain-of-function mutation: increases the activity of the gene or makes it active in inappropriate circumstances; these mutations are usually dominant. dominant-negative mutation: dominant-acting mutation that blocks g ...
PPS - VCU
PPS - VCU

... Biological Regulation: “You are what you express” • Levels of regulation • Methods of measurement • Concept of genomics ...
- North Clarion County School District
- North Clarion County School District

...  Chromatin is a long thin strand of DNA that makes up chromosomes  When a cell is getting ready to divide, the chromatin condenses and wraps around special proteins to give it an X shape.  Each side of a chromosome is called a chromatid, and two chromatids are exact copies of each other. They are ...
Identification of Critical Staphylococcal Genes Using Conditional
Identification of Critical Staphylococcal Genes Using Conditional

... Some strains produce a heat-stable protein toxin that causes illness in humans Enterotoxins produce Staph food poisoning ...
25 transcription, translation
25 transcription, translation

... polysome termination stop codon ...
The Genetics of Alternating Hemiplegia of Childhood A long
The Genetics of Alternating Hemiplegia of Childhood A long

...  Provides sequenced data and variant reports ...
recombinant DNA - Cloudfront.net
recombinant DNA - Cloudfront.net

... • Can be easily grown in suspension culture in a nutrient such as Luria broth • Has a simple circular chromosome with about 1/600th the haploid amount of DNA in a human ...
Supplementary Methods and Tables Supplementary Methods ChIP
Supplementary Methods and Tables Supplementary Methods ChIP

... using a random set of sequences as a control. The main limitations of these methods are that they only explore a defined set of matrices and they require previous manipulations of raw data to identify DNA sequences bound by a transcription factor. Unsupervised prediction methods are extremely powerf ...
Human Genetics Lec 4
Human Genetics Lec 4

... Proteins are made from a standard set of amino acids, which are joined end to end to form the long polypeptide chains of protein molecules. Each polypeptide chain may have as many as 100 to more than 300 amino acids in it. The process of protein synthesis is called translation because the genetic co ...
DNA/RNA
DNA/RNA

... The Human Genome Project is a collaborative effort of scientists around the world to map the entire gene sequence of ...
Population Genetics Sequence Diversity Molecular Evolution
Population Genetics Sequence Diversity Molecular Evolution

... for HIV-1 is CCR-5. a 32-bp deletion mutation in the coding region of the human CCR5 gene has been found that results in an inactive protein. Homozygotes are highly resistant to HIV-1 infection. The allele is found predominantly on a single haplotype, consistent with the notion that it arose once in ...
Identification of Mucin 2 as a Strong Promoter for Gut
Identification of Mucin 2 as a Strong Promoter for Gut

... of gut-specific genes could significantly improve poultry production. In the present study, the mucin 2 promoter is used to drive overexpression of green florescent protein (GFP) in intestinal tissue. Through comparison of gene expression in different tissues, the gut specificity of mucin 2 expressi ...
Chapter 14 - useful links
Chapter 14 - useful links

... Some Human Genes Some of the earliest human genes to be identified were those that determined blood groups. There are a variety of blood groupings, but the most common are the ABO grouping, and the Rh factor grouping. (usually lumped together) Rh factor(a certain protein attached to the blood cell) ...
Cabbage(Brassica oleracea L
Cabbage(Brassica oleracea L

... inhibitor(sporamin)and chitinase genes were in stack constructed using pMSPOA as promoter,. We successfully got ten independent lines through Agrobacterium tumefaciens-mediated transformation,. In trypsin inhibitor or chitinase activity assay, we found that both sporamin and chitinase activity can b ...
Changes in Gene Frequencies
Changes in Gene Frequencies

... • The Hardy-Weinberg theorem (p2+2pq+q2 = 1) describes gene frequencies in a stable population that are well adapted to the environment. It assumes the following: ...
The hematopoietic system has long served as an important model
The hematopoietic system has long served as an important model

... MiDReG is a powerful tool to identify novel genes and cellular stages in development, and is applicable to any developmental pathway where some knowledge of the genes expressed at the beginning and end stages are known. Importantly, in our analysis no intermediate B cell populations were represented ...
An update on ongoing projects within Biorange SP3.2.2.1
An update on ongoing projects within Biorange SP3.2.2.1

... (only the longest peptide per gene) “A”: All peptide sequences from this orthologous group (all peptides per gene) ...
11-1 The Work of Mendel
11-1 The Work of Mendel

... Ex: Does the seed shape gene influence the seed color gene???? INDEPENDENT ASSORTMENT • Need to follow 2 diff. alleles from one generation to the next. ...
punnett square guidelines
punnett square guidelines

... Phenotype: refers to the appearance/what the offspring looks like. EX: Black hair is dominant. A purebred black haired cat is crossed with a hybrid male who also carries a gene for white hair. ...
ESSAY 1: CONCEPTION
ESSAY 1: CONCEPTION

... DNA doesn’t really have all that much control ultimately, because it works in short segments that are coding for enzymes that tell the body what to do, and even those short segments are sometimes controlled by external factors. The segments simply code for proteins and send them around the body, but ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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