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Issues in Biotechnology
Issues in Biotechnology

... 19. The control of gene expression is critical to all living things. The amino acid tryptophan is important for making many proteins. When there is plenty of tryptophan in a cell a protein binds to the gene that codes for enzyme that will make tryptophan. When there is no tryptophan present this pr ...
gene families
gene families

... have been innumerable paracentric inversions within the arms, but very few pericentric inversions that would mix the arms, and relatively few translocations or transpositions between different chromosomes. The autosomal arms themselves have not even been reassociated with each other, e.g. 2L and 2R ...
MOLECULAR RADIOBIOLOGY OF THE ANIMALS GENES
MOLECULAR RADIOBIOLOGY OF THE ANIMALS GENES

... animals genes, such as nature of radiation-induced heritable gene/point mutations and efficiency of densely ionizing radiation, notably neutrons, in gene/point mutation induction are known to be primarily posed and resolved, to a first approximation in accord with level of genetics of the day, by a ...
Who Controls Your DNA
Who Controls Your DNA

... The use of DNA for personal identification by the military may be justified. An individual’s genetic information, however, is a private matter. A recent study at Harvard and Stanford universities turned up more than 200 cases of discrimination because of genes individuals carried or were suspected o ...
Whole Exome Sequencing
Whole Exome Sequencing

... Whole Exome Sequencing (WES) Your doctor may suggest your child have WES if other testing has not provided a reason for your child’s health problems. WES is not perfect and does not always give an answer, so other testing ...
beyond Mendel - the molecular basis of inheritance
beyond Mendel - the molecular basis of inheritance

... – If eye color is located only on the x-chromosome, then females carry to copies of the gene (XX), while males (XY) only carry one – Since the mutant allele is recessive, wa white eyed female must have that allele on both X chromosomes, which would be impossible for F2 females – A white-eyed male ha ...
Slide 1
Slide 1

... cAMP receptor protein (CAP), acting as a homodimer can bind both cAMP and DNA. When glucose is absent (high cAMP state), CAP binds to its positive regulatory element increasing transcription of the lac operon 50-fold. Lac repressor is a tetrameric complex that in the absence of lactose binds tightly ...
Lecture 7 – PDF
Lecture 7 – PDF

... c) the molecular basis involves what are called “trinucleotide repeats” where an increase in the number of repeats increases the severity of the phenotype (this will be discussed later in the course); the incidence of fragile-X syndrome is about 1/2000 births 4. Remember that the pattern of “criss-c ...
[001-072] pierce student man
[001-072] pierce student man

... d. Some RNA molecules are longer than normal. e. RNA is copied from both DNA strands. Explain your reasoning for accepting or rejecting each of these five options. ***9. Enhancers are sequences that affect initiation of transcription occurring at genes that are hundreds or thousands of nucleotides a ...
12. Chau Vu.- Treacher Collins Syndrome
12. Chau Vu.- Treacher Collins Syndrome

...  AddiIonal  eye  abnormaliIes  that  can  lead  to  vision  loss.      absent,  small,  or  unusually  formed  ears.      Defects  in  the  middle  ear  cause  hearing  loss  in  about  half  of  cases.      usually  have  normal ...
Ubiquitous Internal Gene Duplication in Eukaryotes and Intron
Ubiquitous Internal Gene Duplication in Eukaryotes and Intron

... The studies on molecular population genetics typically rely on assays of moderate numbers of individuals at a small numbers of loci, companied with high sampling variance. The high-throughput genomic sequencing methods yield unprecedented power for reliably estimating important parameters in populat ...
Purdue Agricultures Learning a new language of Life By Susan A
Purdue Agricultures Learning a new language of Life By Susan A

... silence particular genes. A gene’s status dictates the orders sent to a cell that control its function and ultimately contributes to disease risk and physical traits in people, animals, plants and other living organisms. It can even affect personality tra its. Researchers, including an interdiscipli ...
Autosomal Non-Mendelian Inheritance
Autosomal Non-Mendelian Inheritance

... flowers will be produced. On a molecular level, this change in color is caused by the availability of free aluminum ions in the soil. In acidic soils, free aluminum ions are typically in higher concentration than in basic soils. Aluminum ions free in the soil are taken up by the hydrangea, and ulti ...
biology 1 - Saddleback College
biology 1 - Saddleback College

... DNA replication - where, when & why does it occur (Chapter 16) • Be prepared to draw, label & explain a diagram of the replication fork (Figure 16.16) • structure of DNA - nitrogenous bases, 5 carbon sugar, phosphate group • types of bonds involved • Chargoff’s rule - base pairing of the nitrogenous ...
Pax6 - MHHE.com
Pax6 - MHHE.com

Practice Exam III
Practice Exam III

... __F_ Man has more DNA per genome than all other organisms. __F_ The number of chromosomes is a direct reflection of the amount of DNA/genome in a species. __F_ All of the DNA in a eukaryote is unique sequence DNA, meaning that it codes for enzymes or recognition signals such as promoters. __F_ Each ...
Birth of a new gene on the Y chromosome of Drosophila melanogaster
Birth of a new gene on the Y chromosome of Drosophila melanogaster

... nucleotide level. Most of them have introns in conserved positions compared with their autosomal paralogs, ruling out retrotransposition and suggesting DNA-based duplication as the mechanism. The original size of these putative duplications is unknown, because the similarity between autosomal and Y- ...
Lecture 10: Nucleic acids (DNA & RNA)
Lecture 10: Nucleic acids (DNA & RNA)

... Types of nucleic acids There are two types of nucleic acids: 1) Deoxyribonucleic acid (DNA): is the genetic material ‫ المادة الوراثية‬in most organisms (humans, animals, bacteria, plants, and some viruses). 2) Ribonucleic acid (RNA): in some viruses, RNA serves as the genetic material.  Nucleic a ...
Ch. 18 – Microbial Models of DNA
Ch. 18 – Microbial Models of DNA

... Control of Viral Genes • Bacteria posses restriction endonucleases, which are enzymes that degrade viral DNA as it enters • Go lysogenic instead – if phage is added to a specific site within bacterial DNA then it’s a prophage and it codes for a protein that represses the other phage genes. • Some b ...
Ch. 18 – Microbial Models of DNA
Ch. 18 – Microbial Models of DNA

... Control of Viral Genes • Bacteria posses restriction endonucleases, which are enzymes that degrade viral DNA as it enters • Go lysogenic instead – if phage is added to a specific site within bacterial DNA then it’s a prophage and it codes for a protein that represses the other phage genes. • Some b ...
Genome and Disease
Genome and Disease

... divisions and, if they disappear completely, the rest of the chromosome will erode and the cell will die. An enzyme called telomerase rebuilds telomeres and is normally only found in germ cells, which divide to make sperm or eggs. However, many human cancers also contain telomerase, meaning that the ...
Chapter 12 - Inheritance Patterns and Human Genetics
Chapter 12 - Inheritance Patterns and Human Genetics

... 1. crossing-over showed genes were at fixed positions on chromosomes 2. genes in a line like a string of beads 3. the farther apart 2 genes are the greater the frequency of crossing-over 4. results of crossing-over appear in offspring as new combinations of traits a. the greater the % of offspring t ...
Chapter 3: Reproduction and Heredity
Chapter 3: Reproduction and Heredity

... Main Idea: An organism’s genes determine its inherited characteristics. Gregor Mendel – honored as the father of genetics. Mendel wondered why the pea plants he grew in his garden had different physical traits. Some were tall, some were short, some produced yellow seeds, and others produced green se ...
REVIEW UNIT 4 & 5: HEREDITY & MOLECULAR GENETICS SAMPLE QUESTIONS
REVIEW UNIT 4 & 5: HEREDITY & MOLECULAR GENETICS SAMPLE QUESTIONS

... The unit of genetic organization in all living organisms is the chromosome. a. Describe the structure and function of the parts of a eukaryotic chromosome. You may wish to include a diagram as part of your description. b. Describe the adaptive (evolutionary) significance of organizing genes into chr ...
Genes and Their Environment Polygenic Inheritance: Inheritance
Genes and Their Environment Polygenic Inheritance: Inheritance

... pressure, and blood cholesterol levels. Of course, these characteristics also have an environmental component. Determining whether a trait is determined by genes or an interaction between genes and the environment can be difficult, but not impossible. In some cases, it is actually quite simple, as w ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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