Technical Targets
... This raises the question as to which set of maturation genes is responsible for building an active CBS hydrogenase and needs to be co-transformed along with the CBS hydrogenase into Synechocystis. Using qRT-PCR to probe gene expression, we found that hyp1 genes (A1, B1, and D1) are specifically indu ...
... This raises the question as to which set of maturation genes is responsible for building an active CBS hydrogenase and needs to be co-transformed along with the CBS hydrogenase into Synechocystis. Using qRT-PCR to probe gene expression, we found that hyp1 genes (A1, B1, and D1) are specifically indu ...
Different strategies of osmoadaptation in the closely
... equilibrium across the cytoplasmic membrane. Osmolytes are organic compounds of low molecular mass that have no influence on cellular metabolism and are non-toxic. Therefore, these highly water-soluble molecules are also called compatible solutes (Brown, 1976; Held et al., 2010). Bacteria accumulate ...
... equilibrium across the cytoplasmic membrane. Osmolytes are organic compounds of low molecular mass that have no influence on cellular metabolism and are non-toxic. Therefore, these highly water-soluble molecules are also called compatible solutes (Brown, 1976; Held et al., 2010). Bacteria accumulate ...
Homeotic genes controlling flower development in Antirrhinum
... flo locus. The flo gene produces a transcript of about 1.6 kb which has the potential to encode a protein, FLO, of 396 amino acids. The FLO amino acid sequence shows no extensive homologies with other sequences in available data-banks (Coen et al. 1990). However, the protein contains a proline-rich ...
... flo locus. The flo gene produces a transcript of about 1.6 kb which has the potential to encode a protein, FLO, of 396 amino acids. The FLO amino acid sequence shows no extensive homologies with other sequences in available data-banks (Coen et al. 1990). However, the protein contains a proline-rich ...
Cloning and characterization of the Xenopus laevis p8 gene
... (Fig. 2c) and, given that Xp8 is localized to the nucleus, it is likely to be a transcription factor. The DNAbinding activity of human p8 is increased with phosphorylation (Encinar et al. 2001) and, while we could not identify any putative phosphorylation sites on Xp8, there were a couple of well-co ...
... (Fig. 2c) and, given that Xp8 is localized to the nucleus, it is likely to be a transcription factor. The DNAbinding activity of human p8 is increased with phosphorylation (Encinar et al. 2001) and, while we could not identify any putative phosphorylation sites on Xp8, there were a couple of well-co ...
Part 4 Student Handout - URMC
... HD gene, some of your gene copies won’t move as far in the gel as normal pieces do. They’ll be closer to the wells on the gel than the normal genes. ...
... HD gene, some of your gene copies won’t move as far in the gel as normal pieces do. They’ll be closer to the wells on the gel than the normal genes. ...
Analysis of acid-induced asr gene promoter of Enterobacteriaceae
... Deletion analysis of asr promoter region upstream the proposed pho box. In order to identify potential cis-regulatory sites in the asr promoter, deletion analysis of the DNA region upstream the –40 position was performed. The consecutive promoter deletions (p∆70, p∆37, p∆20, p∆21, p∆10, p∆4, p∆1 in ...
... Deletion analysis of asr promoter region upstream the proposed pho box. In order to identify potential cis-regulatory sites in the asr promoter, deletion analysis of the DNA region upstream the –40 position was performed. The consecutive promoter deletions (p∆70, p∆37, p∆20, p∆21, p∆10, p∆4, p∆1 in ...
Research Project Final Report
... accessions used to make the diversity sets for cultivated forms of Brassica, oleracea and 14 related wild species (oleracea; alboglabra; atlantica, balearica; bourgaei; cretica; hilaronis; incana; insularis; macrocarpa; montana; robertiana; rupestris; villosa) which are being produced in HH3723 and ...
... accessions used to make the diversity sets for cultivated forms of Brassica, oleracea and 14 related wild species (oleracea; alboglabra; atlantica, balearica; bourgaei; cretica; hilaronis; incana; insularis; macrocarpa; montana; robertiana; rupestris; villosa) which are being produced in HH3723 and ...
Tumour necrosis factor α -308G/A gene polymorphism
... and percentages) in tables. Multiple logistic regression models were used to compare the distribution of genotypes between cases and controls and to determine the association between TNFα308 G/A polymorphism and knee OA. To adjust differences in age, BMI, and gender between the groups, these three v ...
... and percentages) in tables. Multiple logistic regression models were used to compare the distribution of genotypes between cases and controls and to determine the association between TNFα308 G/A polymorphism and knee OA. To adjust differences in age, BMI, and gender between the groups, these three v ...
Gene Section E2F1 (E2F transcription factor 1) Atlas of Genetics and Cytogenetics
... direct transcriptional activation of the ARF tumor suppressor gene by E2F1. ARF sequesters MDM2 away from P53, leading consequently to P53 stabilization and activation. Nevertheless, ARF overexpression may lead to E2F1 downregulation, as ARF targets the latter for proteasomal degradation through skp ...
... direct transcriptional activation of the ARF tumor suppressor gene by E2F1. ARF sequesters MDM2 away from P53, leading consequently to P53 stabilization and activation. Nevertheless, ARF overexpression may lead to E2F1 downregulation, as ARF targets the latter for proteasomal degradation through skp ...
Gene density and transcription influence the localization of
... distal 11p15, including the very gene-rich, subtelomeric T-band 11p15.5. The most distal 4.5 Mb of HSA11p is well characterized due to its association with Beckwith-Wiedemann Syndrome, and because of the cluster of imprinted genes located there. The region contains at least 47 known genes (Redeker e ...
... distal 11p15, including the very gene-rich, subtelomeric T-band 11p15.5. The most distal 4.5 Mb of HSA11p is well characterized due to its association with Beckwith-Wiedemann Syndrome, and because of the cluster of imprinted genes located there. The region contains at least 47 known genes (Redeker e ...
Threshold phenomena versus cell heredity in the
... being claimed that the dark stripes correspond to areas in which Ta is active, with the normal allele active in the intervening agouti areas. The regularity of the stripes is, of course, not easy to explain as the result of a random process (Gr uneberg, 1966 b, 1968), and the fact that the intensity ...
... being claimed that the dark stripes correspond to areas in which Ta is active, with the normal allele active in the intervening agouti areas. The regularity of the stripes is, of course, not easy to explain as the result of a random process (Gr uneberg, 1966 b, 1968), and the fact that the intensity ...
Chapter 9 Patterns of Inheritance Campbell Biology: Concepts & Connections,
... Hippocrates, was an early explanation for inheritance that suggested that – particles called pangenes came from all parts of the organism to be incorporated into eggs or sperm and – characteristics acquired during the parents’ lifetime could be transferred to the offspring. ...
... Hippocrates, was an early explanation for inheritance that suggested that – particles called pangenes came from all parts of the organism to be incorporated into eggs or sperm and – characteristics acquired during the parents’ lifetime could be transferred to the offspring. ...
Potential regulation of gene expression in photosynthetic cells by
... Pfannschmidt et al. — Photosynthetic redox control of gene expression for its regulation. Equal effects of both inhibitors point to consecutive components of the Cytb6f complex as regulators, for instance on stromal components reduced by PSI such as thioredoxins. These inhibitors thus represent use ...
... Pfannschmidt et al. — Photosynthetic redox control of gene expression for its regulation. Equal effects of both inhibitors point to consecutive components of the Cytb6f complex as regulators, for instance on stromal components reduced by PSI such as thioredoxins. These inhibitors thus represent use ...
Gene Section BRAF (v-raf murine sarcoma viral oncogene homolog B1)
... (RBD). These two domains bind to RAS-GTP. CR2, which has 16 aa, is rich in serine and threonine residues, including S365 as an inhibitory phosphorylation site. Finally CR3, which has 293 aa and has the kinase domain, contains also the G-loop GXGXXG motif (highly conserved in most of the human kinase ...
... (RBD). These two domains bind to RAS-GTP. CR2, which has 16 aa, is rich in serine and threonine residues, including S365 as an inhibitory phosphorylation site. Finally CR3, which has 293 aa and has the kinase domain, contains also the G-loop GXGXXG motif (highly conserved in most of the human kinase ...
The Evolution of Populations
... quantitative. Discrete characters, such as the purple or white flower colors of Mendel’s pea plants (see Figure 14.3), can be classified on an either-or basis (each plant has flowers that are either purple or white). Many discrete characters are determined by a single gene locus with different allel ...
... quantitative. Discrete characters, such as the purple or white flower colors of Mendel’s pea plants (see Figure 14.3), can be classified on an either-or basis (each plant has flowers that are either purple or white). Many discrete characters are determined by a single gene locus with different allel ...
Molecular Signatures of Natural Selection for Polymorphic Genes of
... a situation may arise for behavioral variation in populations of interacting and/or competing animals, for example, with the well-known Hawk-Dove game-theory model (Maynard Smith, 1982; Wolf and McNamara, 2012). Similarly, adopting a foraging strategy that is uncommon in a population may reap reward ...
... a situation may arise for behavioral variation in populations of interacting and/or competing animals, for example, with the well-known Hawk-Dove game-theory model (Maynard Smith, 1982; Wolf and McNamara, 2012). Similarly, adopting a foraging strategy that is uncommon in a population may reap reward ...
A locus for posterior polymorphous corneal dystrophy (PPCD3
... membrane and transformation of corneal endothelial cells into cells with an epithelial-like appearance [Krachamer, 1985]. The clinical phenotype of PPCD can vary from relatively benign Descemet’s thickening to severe progression towards vision loss from corneal edema [Cibis et al., 1977; Threlkeld e ...
... membrane and transformation of corneal endothelial cells into cells with an epithelial-like appearance [Krachamer, 1985]. The clinical phenotype of PPCD can vary from relatively benign Descemet’s thickening to severe progression towards vision loss from corneal edema [Cibis et al., 1977; Threlkeld e ...
PDF
... being claimed that the dark stripes correspond to areas in which Ta is active, with the normal allele active in the intervening agouti areas. The regularity of the stripes is, of course, not easy to explain as the result of a random process (Gr uneberg, 1966 b, 1968), and the fact that the intensity ...
... being claimed that the dark stripes correspond to areas in which Ta is active, with the normal allele active in the intervening agouti areas. The regularity of the stripes is, of course, not easy to explain as the result of a random process (Gr uneberg, 1966 b, 1968), and the fact that the intensity ...
A conserved enhancer of the human and murine Hoxa
... 1991; Whiting et al., 1991) the detailed analysis of Hox promoter sequences in transgenic mice identified DNA regions controlling different aspects of Hox gene expression, e.g. limits of expression boundaries and tissue restriction. Based on these results and observations made in Drosophila there is ...
... 1991; Whiting et al., 1991) the detailed analysis of Hox promoter sequences in transgenic mice identified DNA regions controlling different aspects of Hox gene expression, e.g. limits of expression boundaries and tissue restriction. Based on these results and observations made in Drosophila there is ...
Supplementary Data File Supplementary Figures Figure S1
... reference distribution corresponds to a hypothetical data set with 10,000 genes where 2,500 genes are in the low variability category, 5000 in the medium and 2500 in the high variability category. B. The count distribution of Pathway 1 contains a total of 100 genes from the dataset. From these 100 g ...
... reference distribution corresponds to a hypothetical data set with 10,000 genes where 2,500 genes are in the low variability category, 5000 in the medium and 2500 in the high variability category. B. The count distribution of Pathway 1 contains a total of 100 genes from the dataset. From these 100 g ...
Two groups of human herpesvirus 6 identified by sequence
... In this study we investigated the molecular basis for differences between HH¥-6 strain groups by PCR and sequence analysis of 15 variants, including laboratory reference strains from both groups. We also studied, by PCR, strains in two potential patient groups: firstly, low passage isolates from BMT ...
... In this study we investigated the molecular basis for differences between HH¥-6 strain groups by PCR and sequence analysis of 15 variants, including laboratory reference strains from both groups. We also studied, by PCR, strains in two potential patient groups: firstly, low passage isolates from BMT ...
ucscDatabase
... • Most of the information in a GenBank flat file record ends up in the genome database. • The mrna table contains an entry for every mRNA, EST, and RefSeq. • The mrna table itself just contains the GenBank accession, and id’s that link into other tables. ...
... • Most of the information in a GenBank flat file record ends up in the genome database. • The mrna table contains an entry for every mRNA, EST, and RefSeq. • The mrna table itself just contains the GenBank accession, and id’s that link into other tables. ...
Castric et al. (MBE 2010) - GEPV
... times within dominant alleles. The relative magnitude of these two effects remains to be determined, both theoretically and empirically. A second distinctive feature of the molecular evolution of SI genes is the role played by recombination and/or gene conversion. Indeed, whether recombination occur ...
... times within dominant alleles. The relative magnitude of these two effects remains to be determined, both theoretically and empirically. A second distinctive feature of the molecular evolution of SI genes is the role played by recombination and/or gene conversion. Indeed, whether recombination occur ...
the PDF file
... Mitochondrial DNA • There are about 1,700 in every human cell • Each mitochondrion includes an identical loop of DNA about 16,000 base pairs long containing 37 genes. • In contrast, nuclear DNA consists ...
... Mitochondrial DNA • There are about 1,700 in every human cell • Each mitochondrion includes an identical loop of DNA about 16,000 base pairs long containing 37 genes. • In contrast, nuclear DNA consists ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.