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Westwood High School Lesson Plans
Westwood High School Lesson Plans

Physical Chemistry
Physical Chemistry

... chemical energy can be converted into electrical energy. Thermodynamic terms In order to understand and appreciate the power of thermodynamics it is necessary to become familiar with the commonly used terms in thermodynamics. System. A system is a portion of the universe which is selected for invest ...
EVS - RSC - Developments in Microwave Chemistry
EVS - RSC - Developments in Microwave Chemistry

... microwave chemical synthesis has advanced, its applications have been extended to include the synthesis of fine chemicals, organometallic, coordination, intercalation compounds, and nanoparticles. Microwave technology also enables chemists to achieve cleaner and more efficient chemical reactions wit ...
APPROACHES  TO CARBOHYDRATE-BASED  CHEMICAL LIBRARIES:  THE
APPROACHES TO CARBOHYDRATE-BASED CHEMICAL LIBRARIES: THE

Carbon–hydrogen bond activation of chloroalkanes by a rhodium
Carbon–hydrogen bond activation of chloroalkanes by a rhodium

... 2.7. Activation of 1,1,1-trichloroethane The photolysis of 1,1,1-trichloroethane was identical to that of 1-chloropentane except that 4.9 mg of 1 was dissolved in 0.75 ml of 1,1,1-trichloroethane and irradiated at )20 °C for 20 min. The only product observed was the dichloride 2. A control experimen ...
GCSE Chemistry Sample Assessment Materials
GCSE Chemistry Sample Assessment Materials

SCH4U TEXT BOOK
SCH4U TEXT BOOK

... example, CC bonds are considered to be non-polar. Predicting Molecular Polarity A molecule is considered to be polar, or to have a molecular polarity, when the molecule has an overall imbalance of charge. That is, the molecule has a region with a partial positive charge, and a region with a partial ...
Grossmont College Chemistry 120 Laboratory Manual 6th Edition
Grossmont College Chemistry 120 Laboratory Manual 6th Edition

... to mention concentrated solutions of acids and bases, have on protein. The eyes are especially sensitive to acids, bases, and oxidizing agents and must be protected at all times by wearing safety glasses or goggles whenever anyone is working with chemicals or flames in the laboratory. In addition, t ...
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AP Chemistry Unit 7- Homework Problems Equilibrium and Ksp
AP Chemistry Unit 7- Homework Problems Equilibrium and Ksp

... 1. Will a ppt of CaCO3 (Ksp= 3.4 x10-9) form if [Ca+2] = 4 x10-6 M and [CO3-2] = 4 x10-3? Q = [4 x10-6][4x10-3] = 1.6x10-8 >> 3.4x10-9 so yes, ppt 2. Will a ppt of Ag2CrO4 (Ksp = 1.1 x10-12 ) form if [Ag+] = 3x10-4 and [CrO4-2] = 2x10-4? Q = [3 x10-4]2 [2x10-4] = 1.8x10-11 >> 1.1x10-12 so yes, ppt 3 ...
Alberta Chemistry 20-30 Sample CAB Questions - McGraw
Alberta Chemistry 20-30 Sample CAB Questions - McGraw

... central atom is surrounded by three shared pairs of electrons. According to VSEPR theory, these electrons should be as far apart as possible, so that the electrostatic force of repulsion between them is the minimum. In such a case, the three electron pairs arrange themselves in trigonal planar geome ...
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GCSE Chemistry Specification Specification for exams from 2014 2014

Alternative Coverage of moles, molarity, and Chemical Calculations
Alternative Coverage of moles, molarity, and Chemical Calculations

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Answers to Problem-Solving Practice Problems

... (e) Modern quarters (since 1965) are composed of a pure copper core (that can be seen when they are viewed side-on) and an outer layer of 75% Cu, 25% Ni alloy, so they are heterogeneous matter. Pre-1965 quarters are fairly pure silver. (f) Compound; contains carbon, hydrogen, and oxygen 1.6 (a) Ener ...
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... Recall that a balanced equation is one in which both sides have the same number of each kind of atom. As a result, the Law of Conservation of Mass is obeyed, since no atoms can be created nor destroyed. Therefore, the quantities that are conserved in a balanced equation are mass and atoms. Conserved ...
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... acid gases in general using primary amines and amino alcohols as efficient sorption media are limited for this purpose because they do not fit the requirements of regeneration, bio-compatibility and sterilization temperature imposed by the intended applications. Thus, a more complex system has to be ...
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... Peter Mikulecky grew up in Milwaukee, an area of Wisconsin unique for its high human-tocow ratio. After a breezy four-year tour in the Army, Peter earned a bachelor of science degree in biochemistry and molecular biology from the University of Wisconsin–Eau Claire, and a PhD in biological chemistry ...


... removes heat from its surroundings. Therefore, the dissociation of ammonium nitrate in water is endothermic. The system (the cold pack) gains heat as the surroundings lose heat. ...
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... Recall that a solution is a homogeneous mixture. It is the same throughout (the first sip of a cup of coffee is the same as the last), but its composition can be varied by changing the amount of dissolved substances (one can make weak or strong coffee). In this section we will consider what happens ...
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BSc Chemistry Syllabus - St. Xavier`s College

... Mechanism of electrophilic and nucleophilic addition reactions, hydroboration-oxidation, metalammonia and metal reductions (cis and trans), and polymerization. Unit-2: Organic Chemistry-II (15L) (Prerequisites or topics for Self Study:- (i) Importance and application of qualitative and quantitative ...
AS Chemistry - Edexcel
AS Chemistry - Edexcel

... (d) Silicon tetrachloride, SiCl4, is a covalent substance which is a liquid at room temperature. Calculate the number of molecules in 5.67 g of SiCl4. ...
study guide spring 2012
study guide spring 2012

< 1 ... 6 7 8 9 10 11 12 13 14 ... 207 >

Bioorthogonal chemistry



The term bioorthogonal chemistry refers to any chemical reaction that can occur inside of living systems without interfering with native biochemical processes. The term was coined by Carolyn R. Bertozzi in 2003. Since its introduction, the concept of the bioorthogonal reaction has enabled the study of biomolecules such as glycans, proteins, and lipids in real time in living systems without cellular toxicity. A number of chemical ligation strategies have been developed that fulfill the requirements of bioorthogonality, including the 1,3-dipolar cycloaddition between azides and cyclooctynes (also termed copper-free click chemistry), between nitrones and cyclooctynes, oxime/hydrazone formation from aldehydes and ketones, the tetrazine ligation, the isocyanide-based click reaction, and most recently, the quadricyclane ligation.The use of bioorthogonal chemistry typically proceeds in two steps. First, a cellular substrate is modified with a bioorthogonal functional group (chemical reporter) and introduced to the cell; substrates include metabolites, enzyme inhibitors, etc. The chemical reporter must not alter the structure of the substrate dramatically to avoid affecting its bioactivity. Secondly, a probe containing the complementary functional group is introduced to react and label the substrate.Although effective bioorthogonal reactions such as copper-free click chemistry have been developed, development of new reactions continues to generate orthogonal methods for labeling to allow multiple methods of labeling to be used in the same biosystems.
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