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Cell division Objectives
Cell division Objectives

... State that interphase is an active period in the life of a cell when many metabolic reactions occur, including protein synthesis, DNA replication and an increase in the number of mitochondria and/or chloroplasts. Describe the events that occur in the 4 phases of mitosis (prophase, metaphase, anaphas ...
Caylor 102 Biology Unit 3
Caylor 102 Biology Unit 3

... Coined G1, S, and G2 The cell grows during G1 DNA is replicated (synthesis) during S The cell prepares for mitosis during G2 ...
Lesson 12-Mitosis - Northern Highlands
Lesson 12-Mitosis - Northern Highlands

... PROPHASE – longest phase of mitosis • Chromatin (DNA strands) coil up into visible chromosomes • They look kind of hairy! • Each chromosome is made of two identical halves called SISTER CHROMATIDS • These halves are held together by a CENTROMERE ...
Quiz #6
Quiz #6

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Regulation of the Cell Cycle / Cancer

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Objectives Key Terms The Mitosis Dance
Objectives Key Terms The Mitosis Dance

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Bell Work: 1/28/13
Bell Work: 1/28/13

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Cell Gowth & Division ppt
Cell Gowth & Division ppt

... – DNA replication G2 = Organelles ...
Cell cycle: Checkpoint proteins and kinetochores
Cell cycle: Checkpoint proteins and kinetochores

... an intact mitotic spindle will still arrest in mitosis if a single chromosome is not properly attached to the spindle (Figure 1b) [11]. This arrest is caused by an inhibitory signal emanating from kinetochores that are not attached to the spindle apparatus [12]. Genetic studies in yeast have identif ...
Biology Notes: Mitosis
Biology Notes: Mitosis

... 4) Which type of cells divide by mitosis? ________________________________________________________  5) During which interphase stage is DNA created? ________________________________________________  6) During which stage do spindle fibers form? ___________________________________________________  7) ...
Name: Date: Period: ______ Biology Notes: Mitosis Directions: Fill in
Name: Date: Period: ______ Biology Notes: Mitosis Directions: Fill in

... 4) Which type of cells divide by mitosis? ________________________________________________________ 5) During which interphase stage is DNA created? ________________________________________________ 6) During which stage do spindle fibers form? ___________________________________________________ 7) Du ...
Chapter 12 notes
Chapter 12 notes

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MITOSIS
MITOSIS

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Student Academic Learning Services The Cell
Student Academic Learning Services The Cell

... Contrast between mitosis and meiosis by providing four (4) differences between the two types of division. ...
Ch. 6 Section 3 Directed Reading/Quiz
Ch. 6 Section 3 Directed Reading/Quiz

... a. Chromosomes move to the center of the cell and line up along the equator. b. A nuclear envelope forms around the chromatids at each pole. c. Chromosomes coil up and become visible. d. The two chromatids move toward opposite poles as the spindle fibers attached to them shorten. ...
Cell division File
Cell division File

... Purpose: to make copies of cells and their DNA • Replicated chromosomes align at the metaphase plate. • Sister chromatids separate and move to opposite poles. • Nuclear membranes form around each new nucleus. • Division of cytoplasm or cytokinesis occurs. ...
Mitosis Powerpoint - Lemon Bay High School
Mitosis Powerpoint - Lemon Bay High School

... • Kinetochore is the joining of the spindle fiber to the centromere. Improper connection can result in devastating results for the resulting cell. ...
Making New Cells: Mitosis - Social Circle City Schools
Making New Cells: Mitosis - Social Circle City Schools

... chromosomes • Two pair of centrioles move to opposite sides of the nucleus Centrioles ...
Chapter 2 Mitosis and Meiosis
Chapter 2 Mitosis and Meiosis

... • Kinetochore is the joining of the spindle fiber to the centromere. Improper connection can result in devastating results for the resulting cell. ...
Slide 1
Slide 1

... 2. Mitosis – Cell division 3. Cytokinesis – Splitting How long does it take? • Adult human cell: ~24 hrs • 18-20 hours in interphase • 2 hours in mitosis • Embryonic cells: 30 min. ...
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... The Cell Membrane Location: Surround all living cells and organelle. Function: -protect cell and Isolate the cytoplasm from the external ...
Cell Growth & Reproduction II
Cell Growth & Reproduction II

... They are exact copies of each other formed when DNA is copied during interphase. Sister chromatids are held together by a centromere. ...
Plant Cell Mitosis
Plant Cell Mitosis

... order to enter cell division, cells must pass the G2 checkpoint. The G2 checkpoint tests whether the cell copied all the chromosomes correctly. ...
Mitosis PPT - Learning on the Loop
Mitosis PPT - Learning on the Loop

... dying or damaged cells (growth and repair). ...
Chromosomes
Chromosomes

... • Mitosis begins. • All organelles divide so number doubles. • All DNA coils up into chromosomes. • Chromosomes copy themselves. - ...
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Spindle checkpoint



During the process of cell division, the spindle checkpoint prevents separation of the duplicated chromosomes until each chromosome is properly attached to the spindle apparatus. In order to preserve the cell's identity and proper function, it is necessary to maintain the appropriate number of chromosomes after each cell division. An error in generating daughter cells with fewer or greater number of chromosomes than expected (a situation termed aneuploidy), may lead in best case to cell death, or alternatively it may generate catastrophic phenotypic results. Examples include: In cancer cells, aneuploidy is a frequent event, indicating that these cells present a defect in the machinery involved in chromosome segregation, as well as in the mechanism ensuring that segregation is correctly performed. In humans, Down syndrome appears in children carrying in their cells one extra copy of chromosome 21, as a result of a defect in chromosome segregation during meiosis in one of the progenitors. This defect will generate a gamete (spermatozoide or oocyte) with an extra chromosome 21. After fecundation, this gamete will generate an embryo with three copies of chromosome 21.The mechanisms verifying that all the requirements to pass to the next phase in the cell cycle have been fulfilled are called checkpoints. All along the cell cycle, there are different checkpoints. The checkpoint ensuring that chromosome segregation is correct is termed spindle assembly checkpoint (SAC), spindle checkpoint or mitotic checkpoint. During mitosis or meiosis, the spindle checkpoint prevents anaphase onset until all chromosomes are properly attached to the spindle. To achieve proper segregation, the two kinetochores on the sister chromatids must be attached to opposite spindle poles (bipolar orientation). Only this pattern of attachment will ensure that each daughter cell receives one copy of the chromosome.
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