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Medicago Genomics and Bioinformatics
Medicago Genomics and Bioinformatics

... (Baxevanis and Ouellette, 2005). • Gene Ontology (GO) can be used to assess significant functional associations of a gene cluster or a list of significant genes. • Several tools are available to assist the GO-based analysis of microarray data. • Next: pathways and regulatory networks. ...
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... Enzymes that cut DNA molecules at specific sites… • a. are restriction endonucleases. • b. work best in mammals • c. are not needed in DNA fingerprinting ...
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... Is divided into 24 chromosomes 17. Operons Occur only in bacterial genomes Contain more than one gene Contain more than one promoter Were discovered in the 19th century Contain long intergenic sequences ...
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coding and non-coding functions of the genome

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...  Results in an extra copy of chromosome in one cell, and a loss of that chromosome from another. B. Results  After fertilization, the resulting person will have an ...
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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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