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DNA Microarray - School of Biotechnology
DNA Microarray - School of Biotechnology

... • Depending on whether the annotation is used or not, analysis of gene expression data can be classified into two different types, • Supervised learning, we do use the annotation of either the gene or the sample, and create clusters of genes or samples in order to identify patterns that are characte ...
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2) Inactivation of tumour suppressor genes

... The retinoblastoma gene, RB, was the first tumoursuppressor gene to be identified in children with hereditary retinoblastoma and is correlated with a loss of heterozygosity (LOH) at chromosome 13q14.2. Its protein product, RB (~110kD), was subsequently found to be functionally inactivated in several ...
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Unit 4 exam - Geneti..

... B. It determines the characteristics that will be inherited. C. It is exactly the same in all organisms. D. It directly controls the synthesis of starch within a cell. 6. The presence of DNA is important for the cellular metabolic activities because DNA A. is the major component of the cytoplasm B. ...
INS Biology Name: Winter Quarter Midterm
INS Biology Name: Winter Quarter Midterm

... 10. There are 61 mRNA codons that specify an amino acid, but only 45 tRNAs. This is best explained by the fact that a. some tRNAs have anticodons that recognize two or more different codons. b. the rules for base pairing between the third base of a codon and tRNA are flexible. c. many codons are nev ...
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How was the first man

... Using the code, they then used man-made bases to create the chromosome. They put in some extra pieces of DNA to prove that they had created the chromosome. These bases were in a special order to create a code that spelt out the scientists’ names plus an email address that you can email if you crack ...
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Biology 10.2 Review Genes to Proteins

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Genetics and Personality

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Biology 10.2 Review Genes to Proteins
Biology 10.2 Review Genes to Proteins

... In prokaryotes, gene expression is regulated by operons. Gene expression is switched OFF when repressor proteins block RNA polymerase from transcribing a gene. ...
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Notes on Haldane`s mapping function and physical and recomb maps

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... (2) It allows the bacterium to grow in humans, since it contains a human gene. (3) It allows humans to become immune to an infection from this type of bacteria. (4) The bacterium can now produce human cells identical to cells of the DNA donor. ...
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A Chemostat-based Transcriptome Analysis

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GENETICS REVIEWAPRIL26
GENETICS REVIEWAPRIL26

... (2) It allows the bacterium to grow in humans, since it contains a human gene. (3) It allows humans to become immune to an infection from this type of bacteria. (4) The bacterium can now produce human cells identical to cells of the DNA donor. ...
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... has the advantage of being able to capture non-linear similarities, but the disadvantage of ignoring the actual magnitudes of expression changes and their distributions. For ranking genes, there are three options provided based on the uncentered (rank) correlation score calculated. First one is ‘pos ...
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Central Dogma.pptx

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... Peter Jones, director of the Norris Comprehensive Cancer Center at the University of Southern California in Los Angeles, likened epigenetic alterations to the clothes worn by genes. "The clothes are really what determine how the genome works," he said. "The clothes can get tattered by these changes, ...
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chapter 13 lecture slides

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Karyotypes and Mutations

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Genetics 3 - MaxSkyFan

... • There are different four types of bases: A (adenine), T (thymine), G (guanine), and C (cytosine). A always bonds to T, and G always bonds to C. • Thus if you know one strand, you can determine the other ...
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Slide 1

... Assignments include class and home works: • Class works are planned to be completed during the lesson and handed in at the end of it. They will be checked but not graded. • Home works should be handed in the following lesson (two weeks after their hand out). They will be checked and graded. ...
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Introduction o Except for identical twins, have the same DNA. o

... Most genes are the same in all people, but a small number of genes (less than 1 percent of the total) are slightly different between people. What is a gene? ____________________ are forms of the same ____________ with small differences in their sequence of DNA bases. These small differences contribu ...
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Gene Regulation

... “i”. It codes for the lac repressor protein, which plays an essential role in lac operon control. The lac repressor gene is expressed “constitutively”, meaning that it is always on (but at a low level). It is a completely separate gene, producing a different mRNA than the lac operon. • Just upstream ...
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Inter-domain lateral gene transfer

... Atmospheric methane (CH4) is a potent green house gas, with global warming potential 21 times that of CO2. Methane emissions from agriculture represent around 40% of the emissions produced by human activities, thetechnologies to reduce these emissions are lacking. Additionally, cattle typically lose ...
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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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