Spatially restricted domains of homeo-gene
... and the lung (Fig. 4D) . Hox-L .4 transcripts were detected in the thyroid gland but, unlike Hox-1.5 transcripts, were not present generally in tissues that formed the floor of the pharynx (Fig. 48) . Hox-1.4 transcripts were not, therefore, detectable anterior to the thyroid duct . Hox-l .4 transcr ...
... and the lung (Fig. 4D) . Hox-L .4 transcripts were detected in the thyroid gland but, unlike Hox-1.5 transcripts, were not present generally in tissues that formed the floor of the pharynx (Fig. 48) . Hox-1.4 transcripts were not, therefore, detectable anterior to the thyroid duct . Hox-l .4 transcr ...
Direct Deletion Analysis in Two Duchenne Muscular Dystrophy
... hemizygosity was suspected because a similar pattern to that obtained for the father was observed in the proband. Also, a reduction in the signal was seen where the maternal allele (2bp lighter than the paternal one) should have been present (Fig. 2a STR 7A, left arrow). However, the suspected absen ...
... hemizygosity was suspected because a similar pattern to that obtained for the father was observed in the proband. Also, a reduction in the signal was seen where the maternal allele (2bp lighter than the paternal one) should have been present (Fig. 2a STR 7A, left arrow). However, the suspected absen ...
Stage-specific expressions of four different ribonuclease H genes in
... The human pathogen of the genus Leishmania cause worldwide morbidity and infection of visceral organs by some species may be lethal. Lack of rational chemotherapy against these pathogens dictates the study of differential biochemistry and molecular biology of the parasite as compared to its human ho ...
... The human pathogen of the genus Leishmania cause worldwide morbidity and infection of visceral organs by some species may be lethal. Lack of rational chemotherapy against these pathogens dictates the study of differential biochemistry and molecular biology of the parasite as compared to its human ho ...
Correction to “Frequency of Undetected CYP2D6
... Frequency of hybrid genes per sample type The frequency of hybrids genes in CYP2D6*4 and CYP2D6*10 samples is reported for both heterozygous or homozygous and heterozygous alone. We did not determine whether one or both chromosomes contained a hybrid tandem in homozygous samples. For this reason, to ...
... Frequency of hybrid genes per sample type The frequency of hybrids genes in CYP2D6*4 and CYP2D6*10 samples is reported for both heterozygous or homozygous and heterozygous alone. We did not determine whether one or both chromosomes contained a hybrid tandem in homozygous samples. For this reason, to ...
Rearrangements in the Human T-Cell-Receptor Â
... ATL3 is defined on the basis of the clinical picture, distinct morphology of the abnormal lymphocytes, and T-cell markers. Particularly close association of HTLV-I infection with leukemogenesis of ATL has often been reported by a number of serological and epidemiológica! studies (1,2). However, lac ...
... ATL3 is defined on the basis of the clinical picture, distinct morphology of the abnormal lymphocytes, and T-cell markers. Particularly close association of HTLV-I infection with leukemogenesis of ATL has often been reported by a number of serological and epidemiológica! studies (1,2). However, lac ...
Fkh5-deficient mice show dysgenesis in the caudal midbrain and
... embryos and tissues were fixed overnight in Bouin’s solution at room temperature, sectioned (10 µm) and stained with cresyl violet using standard protocols. Whole-mount in situ hybridisation of embryos was performed as described by Wilkinson (1992) using a digoxigeninlabeled antisense RNA probe. For ...
... embryos and tissues were fixed overnight in Bouin’s solution at room temperature, sectioned (10 µm) and stained with cresyl violet using standard protocols. Whole-mount in situ hybridisation of embryos was performed as described by Wilkinson (1992) using a digoxigeninlabeled antisense RNA probe. For ...
Can blue-eyed parents produce brown
... 1B when viewing the iris from the retina at the back of the eye. These layers together determine eye colour through a combination of light absorbance, reflectance and scattering dependent upon the degree of melanin pigmentation within the melanocytes of the stroma, and to a much lesser degree the po ...
... 1B when viewing the iris from the retina at the back of the eye. These layers together determine eye colour through a combination of light absorbance, reflectance and scattering dependent upon the degree of melanin pigmentation within the melanocytes of the stroma, and to a much lesser degree the po ...
Genetics chapt10
... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
Ref - SQA
... chromatids and formation of daughter nuclei. a ii Control of the cell cycle – notes changed to read “ Position and purpose of checkpoints... Mitosis promoting factor (MPF): protein complex controlling the entry of cells into mitosis. a ii Abnormal cell division: cancer cells. Notes amended to read “ ...
... chromatids and formation of daughter nuclei. a ii Control of the cell cycle – notes changed to read “ Position and purpose of checkpoints... Mitosis promoting factor (MPF): protein complex controlling the entry of cells into mitosis. a ii Abnormal cell division: cancer cells. Notes amended to read “ ...
Structural organization of the transfer RNA gene clusters of cholera
... mobilities on gel with those of λ DNA-HindIII fragments. 2.7 Southern blot analysis Briefly, phage φ 149 DNA was digested to completion with various restriction enzymes, singly or with respective double combinations, and the DNA fragments were separated by electrophoresis on vertical 1% agarose gel ...
... mobilities on gel with those of λ DNA-HindIII fragments. 2.7 Southern blot analysis Briefly, phage φ 149 DNA was digested to completion with various restriction enzymes, singly or with respective double combinations, and the DNA fragments were separated by electrophoresis on vertical 1% agarose gel ...
Analyzing microRNA Data and Integrating microRNA with Gene
... regulate many genes, the PutativeGenes list will be much longer than the input microRNA list. The PutativeGenes list might be used for Biological Interpretation. Another useful way to examine the data would be to right-click on the Gene Symbol column (last one on the right) and select Create List w ...
... regulate many genes, the PutativeGenes list will be much longer than the input microRNA list. The PutativeGenes list might be used for Biological Interpretation. Another useful way to examine the data would be to right-click on the Gene Symbol column (last one on the right) and select Create List w ...
Sex Determination and Sex-Linked Characteristics
... other insects, the cells of females have two X chromosomes, whereas the cells of males have a single X. In some insects, they counted the same number of chromosomes in the cells of males and females but saw that one chromosome pair was different: two X chromosomes were found in female cells, whereas ...
... other insects, the cells of females have two X chromosomes, whereas the cells of males have a single X. In some insects, they counted the same number of chromosomes in the cells of males and females but saw that one chromosome pair was different: two X chromosomes were found in female cells, whereas ...
Cutting Edge: DNA Polymerases and Are Dispensable for Ig Gene
... more precisely, that G/C and A/T targeted mutations could be generated by two different steps and/or enzymes (Ref. 24; discussed in Ref. 3). In any event, considering the complete neutral effect of pol deletion on the mutation profile of Ig genes, it appears unlikely that this enzyme is involved a ...
... more precisely, that G/C and A/T targeted mutations could be generated by two different steps and/or enzymes (Ref. 24; discussed in Ref. 3). In any event, considering the complete neutral effect of pol deletion on the mutation profile of Ig genes, it appears unlikely that this enzyme is involved a ...
DFL1, an auxin-responsive GH3 gene homologue, negatively
... multiple auxin-responsive elements, 5¢-GTGCTC-3¢ (Liu et al., 1994). In the promoter region of the DFL1 gene there is also a potential auxin-responsive element, 5¢GTGCAC-3¢. To determine whether DFL1 gene expression is also induced by auxin, we compared the accumulation of the transcript in the wild ...
... multiple auxin-responsive elements, 5¢-GTGCTC-3¢ (Liu et al., 1994). In the promoter region of the DFL1 gene there is also a potential auxin-responsive element, 5¢GTGCAC-3¢. To determine whether DFL1 gene expression is also induced by auxin, we compared the accumulation of the transcript in the wild ...
Human cytochromes P450 in health and disease
... families (sometimes CYP1 and CYP4 families) can profoundly affect drug or metabolite levels in blood or urine; this can lead to therapeutic failure, toxicity or even death—when the patient receives the commonly recommended dosage of a drug. Variants in the CYP1, CYP2A6, CYP2B6, CYP2C, CYP2D6, CYP2E1 ...
... families (sometimes CYP1 and CYP4 families) can profoundly affect drug or metabolite levels in blood or urine; this can lead to therapeutic failure, toxicity or even death—when the patient receives the commonly recommended dosage of a drug. Variants in the CYP1, CYP2A6, CYP2B6, CYP2C, CYP2D6, CYP2E1 ...
Parallel Genetic and Phenotypic Evolution of DNA Superhelicity in
... Losos et al. 1998; Huey et al. 2000). Parallel changes sometimes extend even to the genome, as has been described for some viral and bacterial pathogens (Crandall et al. 1999; Reid et al. 2000). The parallel evolution of DNA superhelicity in the long-term experiment with E. coli provides therefore h ...
... Losos et al. 1998; Huey et al. 2000). Parallel changes sometimes extend even to the genome, as has been described for some viral and bacterial pathogens (Crandall et al. 1999; Reid et al. 2000). The parallel evolution of DNA superhelicity in the long-term experiment with E. coli provides therefore h ...
Lab 3 Procedure
... chromosomal combinations, where n is the haploid number. In humans, n = 23. Thus humans can produce 223 or over eight million different combinations. In addition, meiosis increases variation because during meiosis I, each pair of chromosomes comes together in a process known as synapsis. Chromatids ...
... chromosomal combinations, where n is the haploid number. In humans, n = 23. Thus humans can produce 223 or over eight million different combinations. In addition, meiosis increases variation because during meiosis I, each pair of chromosomes comes together in a process known as synapsis. Chromatids ...
- NRC Research Press
... genomes. The information from physical mapping of each homoeologous chromosome can thus be combined to generate better resolution by producing a single consensus physical map of the wheat Group 5 chromosomes, based on the relative positions of breakpoints with respect to markers across the three hom ...
... genomes. The information from physical mapping of each homoeologous chromosome can thus be combined to generate better resolution by producing a single consensus physical map of the wheat Group 5 chromosomes, based on the relative positions of breakpoints with respect to markers across the three hom ...
trans - bioRxiv
... bioRxiv preprint first posted online Jul. 15, 2014; doi: http://dx.doi.org/10.1101/007153. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license. ...
... bioRxiv preprint first posted online Jul. 15, 2014; doi: http://dx.doi.org/10.1101/007153. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license. ...
Set 2: Mutations
... – Sickle-cell disease – Cystic fibrosis – Thalassemias These mutations are harmful because they alter the DNA sequence, thereby upsetting the structure and function of the protein they code for. Neutral Mutations: Because these often produce little or no change in the phenotype, neutral mutations ar ...
... – Sickle-cell disease – Cystic fibrosis – Thalassemias These mutations are harmful because they alter the DNA sequence, thereby upsetting the structure and function of the protein they code for. Neutral Mutations: Because these often produce little or no change in the phenotype, neutral mutations ar ...
Genetics of mammalian meiosis: regulation, dynamics and impact
... markers, such as disrupted meiotic cDNA 1 homologue (Dmc1) and synaptonemal complex protein 3 (Sycp3) (see below). In fetal testes, which are also exposed to rA from the mesonephroi, Stra8 expression is not induced because a retinoiddegrading enzyme, CyP26B1 (a member of the cytochrome P450 family) ...
... markers, such as disrupted meiotic cDNA 1 homologue (Dmc1) and synaptonemal complex protein 3 (Sycp3) (see below). In fetal testes, which are also exposed to rA from the mesonephroi, Stra8 expression is not induced because a retinoiddegrading enzyme, CyP26B1 (a member of the cytochrome P450 family) ...
Comparative Genomics of Microbes
... between genomes may allow us to understand : – How 2 organisms evolved? – Why certain bacteria cause diseases while others do not? – Identification and prioritization of drug targets ...
... between genomes may allow us to understand : – How 2 organisms evolved? – Why certain bacteria cause diseases while others do not? – Identification and prioritization of drug targets ...