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Linkage Analysis - The Blavatnik School of Computer Science
Linkage Analysis - The Blavatnik School of Computer Science

... The Main Idea/usage: Neighboring genes on the chromosome have a tendency to stick together when passed on to offsprings. Therefore, if some disease is often passed to offsprings along with specific markergenes , then it can be concluded that the gene(s) which are responsible for the disease are loc ...
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How many genes are needed for early detection of breast cancer
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... separated during the generation of the gametes. The progeny inherits one allele from the father and one allele from the mother. Punnett square: Learn how to fill it in and how to use it for deducing geno- and phenotypes in monohybrid and dihybrid crosses. Probability calculations can be used for the ...
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... conduct cross in order to “see” the questionable allele ...
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Inherited Traits and Learned Behaviors

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... fragments of the genomic DNA from the strains to be analyzed were added to this: if this genomic DNA contained the same genes as were present in the array, they bound to them, which could be measured with biochemistry techniques. A microarray analysis allows one to see the differences in the gene co ...
Name: Date - TeacherWeb
Name: Date - TeacherWeb

... 9. What is produced by each parent and shown along the sides of a Punnett square? GAMETES 10. Who carried out the first studies of heredity? GREGOR MENDEL 11. What did he use to carry out these studies? PEA PLANTS 12. Be able to give possible allelic combinations found in gametes Ex:(Bb, Dd) can be ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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