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lac
lac

... -DNA sequence that functions exclusively as a DNA sequence -affects only DNA to which it is physically linked -eg. promoter/operator ...
Isolation and Characterization of Rice MADS Box Gene
Isolation and Characterization of Rice MADS Box Gene

... The expression profile of E31864 in Fig. 2 supports its relatedness to floral development in which API is involved. In contrast, E20969 was found in all tissues examined, although the degree of expression was slightly higher in the panicle at meiotic and flowering stages (Fig. 2). E20969 might act m ...
Final published version
Final published version

... added to a final concentration of 1% (wt/vol), and pH was kept at 6.5 by the automatic addition of 10 M NaOH. Anaerobic conditions were attained by flushing sterile argon through the medium for 1 h preceding inoculation. Strains engineered for the production of mannitol and 2,3-butanediol were grown ...
You`re one in a googol: optimizing genes for protein expression
You`re one in a googol: optimizing genes for protein expression

... scientific literature to realize that the relationship between sequence, host and expression properties is complex (figure 1). It is also clear that there are big gaps in the data available to map this relationship. Previous studies have generally focused on one or a few rules applied to design a sing ...
Figures and figure supplements
Figures and figure supplements

... Figure 2—figure supplement 4. ChIP-seq profiles of H3K4me3 and total histone H3 across high-variance and low-variance genes. (A) Developmental expression profile, from early cleavage to adult, of the highly expressed high-variance genes (n = 1066). Expression levels were measured by CEL-seq and resc ...
A wide-range phylogenetic analysis of Zic proteins: Implications for
A wide-range phylogenetic analysis of Zic proteins: Implications for

... roles in cell fate decision in the early embryonic stages, there seems to be significant phylogenetic variability in these roles. For example, their role in neural development has been demonstrated in the Deuterostomia, but not in the Protostomia. However, in the Cnidaria, hydra Zic (Hyzic) is expre ...
Cloning and functional characterization of temperature responsive
Cloning and functional characterization of temperature responsive

... renewable bio‐products for pharmaceutical and industrial purposes. However, castor oil production does not meet the increase of its world consumption due to the use of cultivars with low genetic potential to adapt to some environmental conditions like harsh temperatures. Castor bean utilises stora ...
Twinning and Embryonic Left-Right Asymmetry
Twinning and Embryonic Left-Right Asymmetry

... fundamental observation is that fusion of embryos results in laterality defects; this clearly demonstrates that splitting of an embryo's left-right field is not required for laterality defects. This is consistent with the chick models which suggest that the asymmetry phenotypes are the result of int ...
Department of Biomedical Informatics
Department of Biomedical Informatics

... The single nucleotide polymorphism (SNP) [pronounced "snip"] is the most common form of genetic variation. As the name suggests, each SNP is a difference in a single nucleotide (A,T,C,or G) of an individual's DNA sequence, such as having AAGG instead of ATGG. There may be from 1 to 10 million SNPs i ...
Molecular pathogenesis of feline leukemia virus
Molecular pathogenesis of feline leukemia virus

... the chromosomal FeLV integration sites can be compared with the map positions in human and mouse chromosomes, and can apply to predict the related adjacent genes. Moreover, some reports have also showed chromosomal aberrations in cats with hematopoietic and lymphoid malignancies (Grindem and Buoen, ...
Interactions Between Genes Controlling Pathogenicity in the Flax
Interactions Between Genes Controlling Pathogenicity in the Flax

... indicating that an AMi/aM, gene pair does occur in the pathogen as predicted by the model: the genotype of the parent strain presumably is iM iMAMiaM,. In this study the observed segregations for pathogenicity on Williston Brown in all three families (Table 1) were consistent with strains CH 5 and I ...
Gene silencing in mammalian cells and the spread of DNA
Gene silencing in mammalian cells and the spread of DNA

... Aprt promoter and the methylation center is methylated on approximately 25% of alleles, and that this level persisted even when the cells were subcloned (Turker et al., 1989). These observations can best be explained by assuming that methylation for CpG sites on a given allele can be either gained o ...
SUPPLEMENTARY INFORMATION TABLE OF CONTENTS: 1
SUPPLEMENTARY INFORMATION TABLE OF CONTENTS: 1

... HART1 and EM1 genomes allowed us to identify quite a reduced number of snoRNAs (Table S8). The HART1 and EM1 Phytomonas genomes show higher similarity to each other than to T. brucei and L. major. Besides, L. major and T.brucei seemed about equally distant from these two genomes with respect to thei ...
powerpoint - McGill University
powerpoint - McGill University

... Effect of the ivermectin (IVE) and selamectin (SEL)] on mitoxantrone (MXR) accumulation mediated by human ABCG2 and murine Abcg2. Transduced MDCKII cells were preincubated with or without Ko143 (1 µM) or the other tested compounds (50 µM). Mean MXR fluorescence is shown in terms of relative arbitrar ...
The Rat Gene Map
The Rat Gene Map

... conserved autosomal chromosome segments is only 33. Of the 20 singletons, 8 appear to be located inside existing segments. The maximal number of conserved segments indicated by the present data set is 61—about half the number of segments found when either species is compared with human. It should be ...
Characterizing the Grape Transcriptome
Characterizing the Grape Transcriptome

... contribute to agronomic properties. Examples include revealing transcriptional pathways that are correlated with berry quality (e.g. metabolism of sugars, organic acids, and flavonoids) and disease resistance (e.g. specific resistance genes and downstream transcriptional pathways) and determining ho ...
the Liver - Saudi Medical Journal
the Liver - Saudi Medical Journal

... associated with embryo loss (8). Anti inflammatory cytokines such as IL10 appear to protect against inflammation-induced miscarriage (9). Research efforts have focused on single nucleotide polymorphisms (SNP) in cytokine genes (1,5), and various SNPs have been reported to be associated with infectio ...
Using GO to improve text information access
Using GO to improve text information access

... promotes a standard way of naming the concepts of the domain) and a system of hierarchical and other relations between and among the concepts and the vocabulary items. The ConverSpeech ontology – BioMedPlus – is a language-oriented ontology. Concepts in BioMedPlus are represented as synonym sets. A ...
The Chromosome Theory of Inheritance
The Chromosome Theory of Inheritance

... flies that were heterozygous for two sex-linked traits. • The results of this experiment included some fruit flies with novel phenotypes. Morgan referred to these flies as recombinant because the combination of alleles on their X chromosome was different from the combinations of alleles present in t ...
Characterization of sex chromosomes in rainbow trout and coho
Characterization of sex chromosomes in rainbow trout and coho

... long arm of the X and Y chromosomes. As in rainbow trout, the sex chromosomes in sockeye salmon are also subtelocentric or uniarmed (Thorgaard, 1978). This chromosome comparison suggests conserved uniarmed morphology of sex chromosomes among these species. Given the evidence of the localization of t ...
Document
Document

... promotes a standard way of naming the concepts of the domain) and a system of hierarchical and other relations between and among the concepts and the vocabulary items. The ConverSpeech ontology – BioMedPlus – is a language-oriented ontology. Concepts in BioMedPlus are represented as synonym sets. A ...
Correcting the Bias of WRIGHT`S Estimates of the Number of Genes
Correcting the Bias of WRIGHT`S Estimates of the Number of Genes

... shows that,dependingon many parameter values, the magnitude of this bias is roughly on the order of m/10. As discussed below, the effect of this bias on the estimation is likely to be small compared with sampling effects. How can we estimate i and z? Generally we do not know i and are not able to es ...
Problem set 1 answer key
Problem set 1 answer key

... involved in a test cross. This cross produces 10 normal-colored snakes and 11 albino offspring. What are the genotypes of the parents and the offspring? The normal-colored female must be heterozygous (Aa) and by definition of a testcross the male must be an albino homozygous (aa). Aa X aa  should r ...
Phytozome Tutorial from David Goodstein
Phytozome Tutorial from David Goodstein

... Clicking any of the checkboxes next to the ontology identifiers will open up the Find related  families tab in the upper row.  The two selected annotations appear now appear under the  heading “Find EurosidI clusters with selected annotation(s)”.  Clicking on that heading will  find gene families th ...
Molecular ecology and selection in the drought-
Molecular ecology and selection in the drought-

... previously surveyed in these populations. This suggests that strong purifying selection has been acting on this gene. In contrast, Asr2 exhibited higher levels of nucleotide diversity, which is indicative of adaptive selection. These patterns were more notable in wild beans than in cultivated common ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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