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... process that is strongly reminiscent of gastrulation contradicts expectations based upon the classical distinction between diploblastic and triploblastic animals and indicates that snail expression was already associated with creation of a new internal tissue layer in the common ancestor of the two ...
Evolutionary dynamics of autosomal-heterosomal rearrangements in
Evolutionary dynamics of autosomal-heterosomal rearrangements in

... many groups of animals, distinguishing even very closely related species and populations [1-4]. As rearrangements would change the position of genes, generating new linkage groups that may lead to an increase of genetic differentiation between populations, they are expected to restrict reproductive ...
DnaJ-related protein essential for placentation - Development
DnaJ-related protein essential for placentation - Development

... in only a portion of mutant conceptuses indicating that the VCAM1/α4 integrin interaction is not the only mechanism mediating chorioallantoic fusion. FGF signaling also plays a role in placental development since a hypomorphic mutation in the FGFR2 gene causes either defects in chorioallantoic fusio ...
Stress Responsive Signal Transduction and the Control of Longevity Dirk Bohmann
Stress Responsive Signal Transduction and the Control of Longevity Dirk Bohmann

... Decrease of the negative regulator Puckered efficiently extends Lifespan ...
Applied and Environmental Microbiology
Applied and Environmental Microbiology

... Jamapa nodulation assays were performed in flasks with agar or vermiculite (13). Nitrogenase activity was measured by acetylene reduction 21 days after inoculation. Student’s t test was performed to analyze the differences between nodule numbers in the different treatments. Bacteroid isolation. Nodu ...
Cloning and characterization of the Xenopus laevis p8 gene
Cloning and characterization of the Xenopus laevis p8 gene

... developing embryos (Figs 5,6). Xp8 expression was detected in the middle body of the prospective neural region at stage 14 (Fig. 5a,b), where it was maintained to stage 18 (Fig. 5c,d). Expression in the prospective neural region extended to the anteroposterior area and branched in the brain area at ...
Off-target Effects: Disturbing the Silence of RNA
Off-target Effects: Disturbing the Silence of RNA

... RNA interference (RNAi) is a post-transcriptional gene regulatory mechanism that can be mediated by endogenously encoded small RNA molecules (microRNAs), or synthetic duplexes referred to as small interfering RNAs (siRNAs). In both cases, these molecules partner with the RNA Induced Silencing Comple ...
Pax8, a murine paired box gene expressed in the developing
Pax8, a murine paired box gene expressed in the developing

... Several paired box sequences have been detected in the mouse genome by hybridization (Dressier et al. 1988). As a first step to understanding the underlying mechanisms by which members of the Pax gene family function, we have sought to identify additional paired box genes of the mouse. In this repor ...
Garrett-Engele* C. M., Siegal*, M. L., Manoli, D. S., Williams, B. C., Li. H., and Baker, B. S.
Garrett-Engele* C. M., Siegal*, M. L., Manoli, D. S., Williams, B. C., Li. H., and Baker, B. S.

... Restriction fragment length polymorphism (RFLP) mapping of intersex To localize ix by RFLP mapping, pairs of closely linked markers flanking the ix locus were employed. The P elements P[w+]4412, inserted at 47D, and P[w+]13403, inserted at 48A, were used (Torok et al., 1993). To generate recombinati ...
Document
Document

... KEY CONCEPT Genes encode proteins that produce a diverse range of traits. A gene is a segment of DNA that tells the cell how to make a particular polypeptide. The location of a gene on a chromosome is called a locus. A gene has the same locus on both chromosomes in a pair of homologous chromosomes. ...
Gene mapping and medical genetics Human chromosome 8
Gene mapping and medical genetics Human chromosome 8

... lipase (LPL) deficiency may result from a primary 8q24 region, where the MYC gene resides.'20 The defect in the LIPD gene itself or from a defect in the major or common rearrangement, t(8;14)(q24;q32), APOC2 gene (on chromosome 19)107 which produces involves a translocation of the MYC locus to the a ...
supplementary materials
supplementary materials

... requires that two conditions be met. First, it is necessary to select an A-A translocation wherein one of the chromosome arms involved in the interchange is the same arm as that borne on the simple B-A chromosome and that the breakpoint in the arm of shared homology of the A-A translocation be dista ...
Bot-genetics basis of inheritance
Bot-genetics basis of inheritance

...  Gene - It is a particular segment of DNA which is responsible for the inheritance and expression of that characterwhich carries information from one generation to next , Gene is equivalent to mendelian factor..  Homologous chromosomes - The morphologically and structurally similar chromosomes pre ...
Gene Finding and Sequence Annotation - Lectures For UG-5
Gene Finding and Sequence Annotation - Lectures For UG-5

... information about the location of a gene (and its structure) on the genome. >Other methods are ‘ab initio’. These methods don’t use existing experimental data (e.g., sequence data as in homology searching) but apply algorithms to identify gene signals in the DNA which may indicate the presence of a ...
Anaerobic protists and hidden mitochondria
Anaerobic protists and hidden mitochondria

... IscU which are present in a double membrane-bound mitochondrial remnant organelle (Tovar et al., 2003). However, with the exception of Nyctotherus ovalis (Hackstein et al., 1999), all mitochondrial remnant organelles, including hydrogenosomes, lack an organelle genome, which was the major distinctio ...
Activation of the JNK pathway during dorsal closure in Drosophila
Activation of the JNK pathway during dorsal closure in Drosophila

File
File

Probing the Performance Limits of the Escherichia
Probing the Performance Limits of the Escherichia

... Microbial stoichiometric models incorporate collections of reactions known to occur in the studied species for simulating metabolism. The complete sequencing of the E. coli genome (Blattner et al., 1997) makes it a model organism for the study presented in this article because extensive knowledge re ...
Origin of the eukaryotic cell
Origin of the eukaryotic cell

... the origin of eukaryotic cell (Albani et al. 2010). The relationship among three domains, Eukaryotes, Bacteria and Archaea, in the tree of life was investigated in this project through phylogenies constructed from two mitochondrial transmembrane proteins HSP70 and HSP60. The trees were rooted with a ...
me-6 - Genetics
me-6 - Genetics

... flanking markers of parental combination represents conversion of the mutant site further from an end of the pairing region; the hybrid-DNA model, on the contrary, predicts that the more frequent class represents conversion of the site nearer an end of the pairing region. In tetrads, a similar relat ...
evolution and mechanism of translation in chloroplasts
evolution and mechanism of translation in chloroplasts

... date, that of Porphyra appears to be the most “primitive” (88). As shown in Figure 2, the IF-1 gene is present only in the ctL23 cluster of land plants. Synechocystis 6803 shares the same gene order as in Synechococcus 6301 except that the IF-1 gene is located between the AK and L36 gene within the ...
lac
lac

... -DNA sequence that functions exclusively as a DNA sequence -affects only DNA to which it is physically linked -eg. promoter/operator ...
data
data

... The vector ps is a 20,000 dimensional vector containing p-values for each statistical test asking if the gene is affected by CD4. However, since we do 20,000 different tests, by random chance, we will have many genes with a p-value <= 0.05. Thus, we must correct the p-values in light of the number o ...
Chapter 23 Population Genetics
Chapter 23 Population Genetics

... Homozygous mutant individuals should occur with a frequency equal to the square of the mutant allele frequency, q. q2 = 0.0001 Taking the square root, q = 0.01 Because p + q = 1, we know that p = 0.99. p = 0.99 and q = 0.01 The frequency of heterozygous carriers is 2pq = ...
Isolation and Characterization of Rice MADS Box Gene
Isolation and Characterization of Rice MADS Box Gene

... The expression profile of E31864 in Fig. 2 supports its relatedness to floral development in which API is involved. In contrast, E20969 was found in all tissues examined, although the degree of expression was slightly higher in the panicle at meiotic and flowering stages (Fig. 2). E20969 might act m ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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