Manipulating the Plasmodium Genome
... to only a third of the predicted genes, but most of these significant matches remain only partially informative. They may reveal the biochemical activity of the product, inherent to the protein and irrespective of cellular context, for example a kinase or a phosphatase activity. They may also indica ...
... to only a third of the predicted genes, but most of these significant matches remain only partially informative. They may reveal the biochemical activity of the product, inherent to the protein and irrespective of cellular context, for example a kinase or a phosphatase activity. They may also indica ...
DNA methylation profiling identifies epigenetic dysregulation in
... modifications are the main molecular events that initiate and sustain epigenetic modifications. These modifications may therefore provide a link between the environment, that is, nutrition and lifestyle, and T2D but only few studies so far have documented aberrant DNA methylation events in T2D (Ling et ...
... modifications are the main molecular events that initiate and sustain epigenetic modifications. These modifications may therefore provide a link between the environment, that is, nutrition and lifestyle, and T2D but only few studies so far have documented aberrant DNA methylation events in T2D (Ling et ...
Against the Central Dogma
... according to several individual peer-reviewed literature references that demonstrate the importance of lncRNAs in diseases such as neurodegeneration and cancer. The workflow for the Disease-Related Human LncProfiler kit starts with extraction of RNA from your cells. Using your own cDNA synthesis rea ...
... according to several individual peer-reviewed literature references that demonstrate the importance of lncRNAs in diseases such as neurodegeneration and cancer. The workflow for the Disease-Related Human LncProfiler kit starts with extraction of RNA from your cells. Using your own cDNA synthesis rea ...
Winge`s sex-linked color patterns and SDL in the guppy: genes or
... derivative of the word pangenesis which Darwin (1868) coined. Even not very precisely, the definition of Johannsen (1909, 1911) remained for a long time a good one for understanding the concept of gene. The nature of gene remained unknown even after Morgan’s experiences (1919) who considered genes a ...
... derivative of the word pangenesis which Darwin (1868) coined. Even not very precisely, the definition of Johannsen (1909, 1911) remained for a long time a good one for understanding the concept of gene. The nature of gene remained unknown even after Morgan’s experiences (1919) who considered genes a ...
AACL BIOFLUX
... derivative of the word pangenesis which Darwin (1868) coined. Even not very precisely, the definition of Johannsen (1909, 1911) remained for a long time a good one for understanding the concept of gene. The nature of gene remained unknown even after Morgan’s experiences (1919) who considered genes a ...
... derivative of the word pangenesis which Darwin (1868) coined. Even not very precisely, the definition of Johannsen (1909, 1911) remained for a long time a good one for understanding the concept of gene. The nature of gene remained unknown even after Morgan’s experiences (1919) who considered genes a ...
PDF
... Genetic resistance to rice BB has been extensively used by rice breeders to combat this disease and breakdown of resistance in varieties having a single resistance gene has been reported in rice (Mew et al., 1992; Nelson et al., 1994; George et al., 1997) after 2 or 3 years as a result of shifts in ...
... Genetic resistance to rice BB has been extensively used by rice breeders to combat this disease and breakdown of resistance in varieties having a single resistance gene has been reported in rice (Mew et al., 1992; Nelson et al., 1994; George et al., 1997) after 2 or 3 years as a result of shifts in ...
Yet viruses cannot be included in the tree of life - Université Paris-Sud
... surrounding natural world. It is neither metaphysical, as Koonin et al.6 state, nor religious (even much less so) as unfoundedly claimed7. As biological scientists, we deal exclusively with empirical data from the material world, from which we extract information that allow hypotheses to be construc ...
... surrounding natural world. It is neither metaphysical, as Koonin et al.6 state, nor religious (even much less so) as unfoundedly claimed7. As biological scientists, we deal exclusively with empirical data from the material world, from which we extract information that allow hypotheses to be construc ...
Ribosome profiling reveals post-transcriptional buffering of divergent
... role in divergent mRNA abundance than in divergent translation efficiency. Strikingly, most genes with aberrant transcript abundance in F1 hybrids (either over- or underexpressed compared to both parent species) did not exhibit aberrant ribosome occupancy. Our results show that interspecies differen ...
... role in divergent mRNA abundance than in divergent translation efficiency. Strikingly, most genes with aberrant transcript abundance in F1 hybrids (either over- or underexpressed compared to both parent species) did not exhibit aberrant ribosome occupancy. Our results show that interspecies differen ...
The CpG island methylator phenotype (CIMP) in
... promoter CpG island sites, resulting in the inactivation of several tumor suppressor genes or other tumor-related genes (17). Role of Epigenetics in normal cells and cancer cells Epigenetic regulation of gene expression is a general key mechanism that is operative in normal tissues and has an import ...
... promoter CpG island sites, resulting in the inactivation of several tumor suppressor genes or other tumor-related genes (17). Role of Epigenetics in normal cells and cancer cells Epigenetic regulation of gene expression is a general key mechanism that is operative in normal tissues and has an import ...
Tabby pattern genetics – a whole new breed of cat
... doing so, it may be helpful to consider what types of developmental and cellular mechanisms might be involved. Eizirik et al. (2010) suggest that mammalian coat patterns are formed by two distinct processes: (i) a ‘spatially oriented’ mechanism that establishes a prepattern in the skin and (ii) a ‘p ...
... doing so, it may be helpful to consider what types of developmental and cellular mechanisms might be involved. Eizirik et al. (2010) suggest that mammalian coat patterns are formed by two distinct processes: (i) a ‘spatially oriented’ mechanism that establishes a prepattern in the skin and (ii) a ‘p ...
Hardy Weinberg Equilibrium Problems
... 11. Sickle-cell anemia is a disease caused by the inheritance of a dominant sickle gene. This gene is codominant with the normal hemoglobin gene. In a certain African tribe, 4% of the population is born with sickle-cell disease having inherited both dominant sickle genes. What is the percentage of i ...
... 11. Sickle-cell anemia is a disease caused by the inheritance of a dominant sickle gene. This gene is codominant with the normal hemoglobin gene. In a certain African tribe, 4% of the population is born with sickle-cell disease having inherited both dominant sickle genes. What is the percentage of i ...
Analysis of Two Genes Encoding Prothrombin Activators in
... be used as the cis-element contributing to the regulation for reporter gene expression. Next, in recognising for any important upstream promoter element, a 5’ deletion study can be performed on the whole FV and PCNS promoter region before continuing the DNA sequencing of this unfinished region (Chen ...
... be used as the cis-element contributing to the regulation for reporter gene expression. Next, in recognising for any important upstream promoter element, a 5’ deletion study can be performed on the whole FV and PCNS promoter region before continuing the DNA sequencing of this unfinished region (Chen ...
Detecting transposon-induced genomic variants using low
... low-coverage sub-samples of genomic reads to retrieve and specifically assemble the highly repeated elements. All these tools have the advantage to give a good picture of the global TE abundance and diversity. However they do not provide the exact genomic positions of each TE, preventing the identif ...
... low-coverage sub-samples of genomic reads to retrieve and specifically assemble the highly repeated elements. All these tools have the advantage to give a good picture of the global TE abundance and diversity. However they do not provide the exact genomic positions of each TE, preventing the identif ...
Carbapenemase and virulence factors of
... Objectives: To investigate the resistance to carbapenems in Enterobacteriaceae and the underlying resistance mechanisms in North Lebanon between 2008 and 2012. Methods: A total of 2767 Enterobacteriaceae isolates recovered from clinical samples collected in Nini Hospital (North Lebanon) were screene ...
... Objectives: To investigate the resistance to carbapenems in Enterobacteriaceae and the underlying resistance mechanisms in North Lebanon between 2008 and 2012. Methods: A total of 2767 Enterobacteriaceae isolates recovered from clinical samples collected in Nini Hospital (North Lebanon) were screene ...
Future Dog Breeding for Genetic Soundness
... aggregates deleterious genes, producing disorders that may not be apparent in every generation. These disorders often go undetected until the condition becomes frequent enough to be recognized as inherited.Generations may be unaffected when carriers are rare. As unaffected carriers become common, mo ...
... aggregates deleterious genes, producing disorders that may not be apparent in every generation. These disorders often go undetected until the condition becomes frequent enough to be recognized as inherited.Generations may be unaffected when carriers are rare. As unaffected carriers become common, mo ...
Conserved syntenic clusters of protein coding genes are missing in
... basal avian order with a high quality genome assembly, and an oscine passeriform (zebra finch; Taeniopygia guttata; Figure 1). We initially focused on chicken and zebra finch, since these represented the best assembled and curated avian genomes available in Ensembl at the time we began this study. O ...
... basal avian order with a high quality genome assembly, and an oscine passeriform (zebra finch; Taeniopygia guttata; Figure 1). We initially focused on chicken and zebra finch, since these represented the best assembled and curated avian genomes available in Ensembl at the time we began this study. O ...
in yeast pontecorvo, roper, hemmons, jacob
... could be explained if crossing over was frequent in all chromosomes in any one nucleus. In the present paper these segregations in yeast are described in detail and are discussed in terms both of the mechanism of mitotic crossing over and of a mechanism of meiotic crossing over followed by restituti ...
... could be explained if crossing over was frequent in all chromosomes in any one nucleus. In the present paper these segregations in yeast are described in detail and are discussed in terms both of the mechanism of mitotic crossing over and of a mechanism of meiotic crossing over followed by restituti ...
Mutations in the MicroRNA Complementarity Site
... carpels. Our results suggest that the ICU4 gene has an adaxializing function and that it is down-regulated by microRNAs that require the HASTY protein for their biogenesis. ...
... carpels. Our results suggest that the ICU4 gene has an adaxializing function and that it is down-regulated by microRNAs that require the HASTY protein for their biogenesis. ...
Genetic evaluation with major genes and polygenic inheritance
... between genotype at the major gene and the phenotype can be estimated using standard EM-REML or Gibbs sampling. Prediction of breeding values with genotypes at the major gene can use multiple-trait BLUP software. Major genes with more than two alleles can be considered by including negative covarian ...
... between genotype at the major gene and the phenotype can be estimated using standard EM-REML or Gibbs sampling. Prediction of breeding values with genotypes at the major gene can use multiple-trait BLUP software. Major genes with more than two alleles can be considered by including negative covarian ...
Genetic and epigenetic risks of intracytoplasmic sperm injection
... (PGD) is recommended for couples who are both positive for CF mutations and wish to integrate ICSI and genetic diagnosis at early stages of the embryonic development [21, 22]. Josserand et al. [23] detected CFTR mutations on 56 alleles of 50 males with congenital bilateral absence of vas deferens. A ...
... (PGD) is recommended for couples who are both positive for CF mutations and wish to integrate ICSI and genetic diagnosis at early stages of the embryonic development [21, 22]. Josserand et al. [23] detected CFTR mutations on 56 alleles of 50 males with congenital bilateral absence of vas deferens. A ...
6.3 Mendel and Heredity
... • Molecular genetics – study of the structure and function of chromosomes and genes • Gene – segment of DNA on a chromosome that controls a particular hereditary trait • Letters are used to represent alleles of genes - capital letters refer to dominant alleles ...
... • Molecular genetics – study of the structure and function of chromosomes and genes • Gene – segment of DNA on a chromosome that controls a particular hereditary trait • Letters are used to represent alleles of genes - capital letters refer to dominant alleles ...
Causes, consequences and solutions of
... Phylogenetic analysis is used to recover the evolutionary history of species, genes or proteins. Understanding phylogenetic relationships between organisms is a prerequisite of almost any evolutionary study, as contemporary species all share a common history through their ancestry. Moreover, it is i ...
... Phylogenetic analysis is used to recover the evolutionary history of species, genes or proteins. Understanding phylogenetic relationships between organisms is a prerequisite of almost any evolutionary study, as contemporary species all share a common history through their ancestry. Moreover, it is i ...