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supplementary material
supplementary material

... Significantly regulated genes were annotated using the web based annotation tools SOURCE (13) and the Database for Annotation, Visualization and Integrated Discovery (DAVID) (14) version 2.0 as described in the manuals. 8) Enriched functional categories: Enriched functional categories within the dif ...
LINKAGE - TYPES OF LINKAGE AND ESTIMATION OF LINKAGE
LINKAGE - TYPES OF LINKAGE AND ESTIMATION OF LINKAGE

... to the same gamete and the same offspring. Thus, the parental combination of traits is inherited as such by the young one. Incomplete Linkage The genes distantly located in the chromosome show incomplete linkage because they have a chance of separation by crossing over and of going into different ga ...
Mendelian Inheritance - Santa Susana High School
Mendelian Inheritance - Santa Susana High School

... recessive allele - has no noticeable contribution to an organism's appearance if a dominant allele is also present(symbolized by a lower cased letter of the dominant trait) wildtype - the dominant trait expressed in the highest ratio in nature genotype - organisms genetic makeup phenotype - organism ...
Midterm 2 2012 KEY
Midterm 2 2012 KEY

... 17. A zebrafish mutant named floating head lacks a notochord. Explain why the researchers chose the name floating head for the gene involved. Genes are often named after the mutant phenotype. In this case, mutation of floating head leads to the absence of a notochord, which in turn, leads to the lac ...
Genetics Part 1
Genetics Part 1

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HTM_moran_4
HTM_moran_4

... Determine Highly and Lowly Reaction sets 1. Genes set :Extract set of enzymes whose expression is significantly increased or decreased (GeneNote, HPRD) 2. Reactions set :Employ a detailed gene-to-reaction mapping to identify a tissue-specific expression state for each reaction ...
Comment on: Resistance gene naming and
Comment on: Resistance gene naming and

... Four alleles of the oxaAr gene, each encoding a protein with a different OXA number, were listed in the database, but sequence was available for only one of them. It differed from oxa23 at 20 positions in a gene length of 822 bp (2.4%). However, the oxaAr gene does not meet two of the criteria we pr ...
Genetics Notes: This is a general outline of what you need to know
Genetics Notes: This is a general outline of what you need to know

... DNA language has the following 4 letters; ____________________________________________ DNA words are always _________letters long and they form _______________ or ____________ In the DNA language there are ___________________ words (or amino acids). DNA sentences create ____________________ with a s ...
Chapter2 - EDUC111ChildGrowthDevelopment
Chapter2 - EDUC111ChildGrowthDevelopment

... chromosomes. A girl inherits two X chromosomes; a boy inherits an X and a Y. The mother passes on only X chromosomes; the father can pass on an X or a Y. Consequently, it is the father’s sperm that determines the sex of the baby. Most of the traits we inherit result from a combination of several gen ...
Serial Analysis of Gene Expression
Serial Analysis of Gene Expression

... Long SAGE vs. Short SAGE •A comparison of short SAGE (14bp) vs. long SAGE (21bp) •Some tags are not unambiguously assigned to a gene (similar 3’ ends due to ancestral duplications) •About 12% of C. elegans tags are not unambiguously identified using 14bp tags ...
Name: Hour
Name: Hour

... •Inherited traits are determined by __________. Genes are passed from parents to offspring •Some forms of the gene may be _________________ and others may be _________________ •The genes ___________________ during meiosis so only one copy of a gene goes into the gamete •Alleles for different genes u ...
Non-coding RNAs
Non-coding RNAs

... -symptoms by 5 yrs, in wheelchair by 11 yrs, death in or early 20s • 5-10% of carrier females have muscle weakness, a few severe disease • very large gene (>2.5 Mb) -protein is called dystrophin -most mutations are deletions -Becker Muscular Dystrophy is allelic ...
Unit 3 Review Notes
Unit 3 Review Notes

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Biology Chapter 14 TEST (2010)
Biology Chapter 14 TEST (2010)

... ____ 35. If nondisjunction occurs during meiosis, a. only two gametes may form instead of four. b. some gametes may have an extra copy of some genes. c. the chromatids do not separate. d. it occurs during prophase. ____ 36. Nondisjunction can involve a. autosomes. b. sex chromosomes. c. homologous ...
Chapter 18: Regulation of Gene Expression
Chapter 18: Regulation of Gene Expression

... DNA methylation is the process of adding methyl groups to DNA bases. At least in some species, DNA methylation seems to be essential for the long-term inactivation of genes that occurs during normal cell differentiation in the embryo. ...
Some Problems with Genetic Horoscopes
Some Problems with Genetic Horoscopes

... futures? If we clone a human being, will the cloned person develop identical propensities as those of the originator of its DNA? And if not, why not? If it’s not all in your genes, where else does “it” (you) come from? I must start by stating very clearly that there are cases where genetic counselin ...
Chromosomal Disorders
Chromosomal Disorders

... Chromosomal Disorders Chromosomal deletion: when cells go through meiosis, portions of the chromosome are lost.  Chromosomal inversion: when cells go through meiosis, parts of the chromosome are flipped.  Chromosomal translocation: when cells go through meiosis, parts of the chromosomes stick tog ...
Chromosomal Disorders
Chromosomal Disorders

... Chromosomal Disorders Chromosomal deletion: when cells go through meiosis, portions of the chromosome are lost.  Chromosomal inversion: when cells go through meiosis, parts of the chromosome are flipped.  Chromosomal translocation: when cells go through meiosis, parts of the chromosomes stick tog ...
Chapter 9: Patterns of Inheritance
Chapter 9: Patterns of Inheritance

... The Punnett Square …is useful for determining expected results of a cross: 1) write out the cross (i.e., the genotypes of each parent) 2) indicate all possible gametes for each parent on either axis of a Punnet square 3) fill in all possible fertilizations (i.e., combinations of gametes) 4) determi ...
The On’s and Off’s of Gene Expression
The On’s and Off’s of Gene Expression

... – Expressed all the time, in many cell types – Examples include factors for: glucose metabolism; RNA and protein synthesis; ATP synthesis ...
CHAPTER 10
CHAPTER 10

... have been sequenced. • In 2004 the “finished” version of the human genome was reported. – It contains about 20,000 genes. – Alternate splicing of messenger RNA may account for several proteins from one gene. – Post-translational modifications also account for different protein functions. ...
Racial Mixing - An Overview - Mendelan Laws of InheritancePart 4
Racial Mixing - An Overview - Mendelan Laws of InheritancePart 4

... If that mixed race individual then marries back into the White genotype pool, statistically, only half that person’s progeny will carry (a), and only half of the next generation. A mutant allele may simply disappear or it may propagate out through many generations before it reappears through mixing ...
Mutation Screening in KCNQ1, HERG, KCNE1, KCNE2 and SCN5A
Mutation Screening in KCNQ1, HERG, KCNE1, KCNE2 and SCN5A

... KCNE2 and SCN5A genes in a LQTS family. Genetic polymorphisms in the cardiac ion channel genes under study account for the vast majority of LQTS cases. Both non-synonymous polymorphisms (P448R-KCNQ1 and G38S-KCNE1) are relatively frequent among the normal Chinese population, with allele frequencies ...
GENE EXPRESSION ANALYSIS
GENE EXPRESSION ANALYSIS

... Gene expression analysis is often an integral component of feed and vaccine trials. Xelect is a spin-out company from a University research group with substantial expertise in fish genomics and gene expression analysis including experimental design and normalisation strategies. Xelect offers a compl ...
Slide 1
Slide 1

... Most genes are identical in men and women. However, there’s one that’s different between the genders. Women have two, larger “X” chromosomes, while men only have 1 larger “X” chromosome, and the shorter “Y” chromosome. There are some genes that appear on these “X” chromosomes that do not appear on t ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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