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UBC - UCSB Economics
UBC - UCSB Economics

... The first lamb’s own survival probability is an increasing function of x. The earlier she weans, the stronger the ewe will be when she bears her second lamb, so the second lamb’s survival probability is a decreasing function of x. ...
The Human Genome Project
The Human Genome Project

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Chapter 14 Study Workbook
Chapter 14 Study Workbook

... They used “shotgun sequencing,” which uses a computer to match DNA base sequences. To identify genes, they found promoters, exons, and other sites on the DNA molecule. To locate and identify as many haplotypes (collections of linked single-base differences) in the human population as possible, the I ...
Human Inheritance
Human Inheritance

Mendel and Heredity
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... that considers two pairs of contrasting characters Mendel found that for the characters he studied, the inheritance of one character did not influence the inheritance of any other character ...
Chapter 10: Genes and Chromosomes
Chapter 10: Genes and Chromosomes

... ___________________ of that chromosome in another cell ...
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...  Being heterozygous makes proteins completely nonfunctional though have both normal and bad (?) proteins—is dominant Incomplete dominance o Gene encoding an enzyme or protein that, e.g. makes colour  If have 0 WT, will have white; 1 WT, will get a lighter colour; if have 2 WT, will get dark colour ...
Unit 4. Week 2. Meiosis and Reproduction
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... a. Cells only divide through mitosis and cytokinesis so the body can grow and repair itself b. If you get a cut, your skin cells will divide rapidly to heal the wound. When you’re almost healed, the cell division will slow down and then stop. ...
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... Nguni genome variation • To provide the first resources to facilitate the understanding of the genetic value of Nguni cattle • Target: 10 genomes at 10x coverage • Progress: 9 genomes at 10-12x coverage ...
Introduction to Genetics using Punnett Squares
Introduction to Genetics using Punnett Squares

... Gregor Mendel was an Austrian monk and is known as the Father of Genetics.  Mendel was the gardener and observed that many of the plants looked different even though they were the same species.  He studied pea plants and their traits to see how they were passed on. This lead to our basic understan ...
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PPT: Genetics: From Mendel to Genome and Epigenome
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... The Greek prefix “epi” means “on top of” or “over”, so the term “Epigenetics” literally describes regulation at a level above, or in addition to, those of genetic mechanisms. Robin Holliday and John Pugh proposed that changes in gene expression during development depends on the methylation of specif ...
Transcription, chromatin condensation, and gene
Transcription, chromatin condensation, and gene

... tion induction. It is widely believed that chromatin is extensively compacted within nuclei, but that transcriptionally active regions decondense to the level of DNA wrapped around nucleo­ somes, namely a 10-nm fiber. To investigate chromatin or­ ganization in a transcriptionally active region, the ...
Linkage mapping of the gpdA gene of
Linkage mapping of the gpdA gene of

... In the last few years many genes of several Aspergillus species have been cloned and sequenced. For many of these genes mutant alleles and genetic linkage data are also available. However, for those genes for which no mutant alleles have been isolated, genetic mapping was not possible. Here we repor ...
Cloning genes by complementation
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... Problems that prevent the use of complementation to screen for genes in higher organisms 1)- Higher organisms have much larger genome size. More than 5x106 plasmids would be needed to screen the human genome. 2)- Higher organisms are multicellular and therefore the cloned DNA has to enter all body c ...
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... with Synthetic Smallpox Genes Sandia National Laboratory, part of the US Department of Energy, has initiated experiments with smallpox genes engineered into other organisms. The genes were inserted into the other bugs in order to produce smallpox proteins for undisclosed purposes. According to Sandi ...
Mendelian Genetics
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... Inherited traits: Characteristics that are inherited or passed on from parents to offspring Acquired traits: characteristics that you get as you go through life (not inherited) Gregor Mendel: the father of genetics. ˃ Mendelian Genetics ˃ He worked with garden pea inheritance in the 1800’s. ˃ His id ...
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... attaches to a non-homologous chromosome • Ex: Translocation Down Syndrome – translocation between chromosomes 21 and 14 – inheritance of two normal copies of chromosome 14 and one that has a piece of chromosome 21 attached to it – the extra material from chromosome 21 causes Down Syndrome (like Tris ...
Chapter 7 – Recombination in Bacteria and
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... 1) In Hfr strains, F factor is integrated into the bacterial chromosome promoting transfer of chromosomal genes (Figure 7-6) 2) there is a fixed point at which transfer begins (origin) and a linear order to the transfer process of the genes (Figure 7-8) 3) the time taken to transfer a gene is relate ...
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... or confined to rare ecosystems. It forms white colonies of 2–5 mm diameter in 48 h that smell faintly of elementary sulfur if grown on thiosulfate-containing basal salts agar. In batch cultures, thiosulfate is oxidized stoichiometrically to tetrathionate early in the exponential phase, resulting in ...
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... collaborative, online building of a data set accomplished by the students and the genome analysis done by the researchers (on a larger scale). Students could post their 3-2-1 analyses as blog posts (on a class blog or individual student blogs). Once posted, the comments feature could be used to faci ...
Alternative splicing
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... After finish the genome sequencing projects, it was realized that only less of the genes had been previously characterized. Two methods are currently used to assign the function of a gene based only on its sequence. ...
Origin of the Science of genetics
Origin of the Science of genetics

... Sex-linked Genes • Genes on the X chromosome are called “sexlinked”, because they expressed more often in males than in females • There are very few genes on the Y chromosome. • Since males only have one X chromosome, all genes on it, whether dominant or recessive, are expressed. ...
Genes and Medical Genetics
Genes and Medical Genetics

... – Skeletal deformities (including a large head) – May develop eye and ear tumors  become blind and deaf ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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