Blueprint of life
... After eight years of collecting data from nearly 30 000 pea plants, Mendel discovered the natural laws of inheritance. Mendel’s findings on plant hybridisation were presented in two lectures before the Society for the Natural Sciences in 1865 in Brünn, Moravia (now called Brno in the Czech Republic) ...
... After eight years of collecting data from nearly 30 000 pea plants, Mendel discovered the natural laws of inheritance. Mendel’s findings on plant hybridisation were presented in two lectures before the Society for the Natural Sciences in 1865 in Brünn, Moravia (now called Brno in the Czech Republic) ...
The cytogenetics of homologous chromosome pairing in meiosis in plants Meiosis
... Numerous plant mutants in early recombination genes show defects in chromosome pairing in addition to their recombination defects, indicating that pairing requires initiation of meiotic recombination and progression through early steps of the recombination pathway (Pawlowski and Cande, 2005; Hamant ...
... Numerous plant mutants in early recombination genes show defects in chromosome pairing in addition to their recombination defects, indicating that pairing requires initiation of meiotic recombination and progression through early steps of the recombination pathway (Pawlowski and Cande, 2005; Hamant ...
The cytogenetics of homologous chromosome pairing in meiosis in
... DMC1 is chiefly responsible for DSB repair using the homologous chromosome as a template. RAD51 predominantly repairs meiotic DSBs using a sister chromatid as template, instead of the homologous chromosome. Studies on yeast and mouse, show that following SEI, the meiotic recombination pathway splits ...
... DMC1 is chiefly responsible for DSB repair using the homologous chromosome as a template. RAD51 predominantly repairs meiotic DSBs using a sister chromatid as template, instead of the homologous chromosome. Studies on yeast and mouse, show that following SEI, the meiotic recombination pathway splits ...
Rosana Segovia HGT - Repositorio Digital USFQ
... The growing presence of multi-drug resistant phenotypes in Enterobacteriaceae that are associated with clinical cases of urinary tract infection, pneumonia, meningitis, and bacteremia have been well established (5-6, 13, 18). In addition, it is known that this increase occurs primarily through clona ...
... The growing presence of multi-drug resistant phenotypes in Enterobacteriaceae that are associated with clinical cases of urinary tract infection, pneumonia, meningitis, and bacteremia have been well established (5-6, 13, 18). In addition, it is known that this increase occurs primarily through clona ...
PpASCL, a moss ortholog of antherspecific chalcone synthaselike
... (PKSA), which encodes an anther-specific chalcone synthase-like enzyme (ASCL), have been shown to be involved in sporopollenin biosynthesis. The genome of the moss Physcomitrella patens contains putative orthologs of the Arabidopsis sporopollenin biosynthesis genes. • We analyzed available P. patens ...
... (PKSA), which encodes an anther-specific chalcone synthase-like enzyme (ASCL), have been shown to be involved in sporopollenin biosynthesis. The genome of the moss Physcomitrella patens contains putative orthologs of the Arabidopsis sporopollenin biosynthesis genes. • We analyzed available P. patens ...
Chap 13
... The parents of a child with unusual disease symptoms take the child to a doctor for help. The doctor suspects that the condition might have a genetic basis. She recommends that the child be taken to a specialty clinic where physicians and staff members are trained to diagnose genetic diseases and c ...
... The parents of a child with unusual disease symptoms take the child to a doctor for help. The doctor suspects that the condition might have a genetic basis. She recommends that the child be taken to a specialty clinic where physicians and staff members are trained to diagnose genetic diseases and c ...
PDF
... PHAVOLUTA (PHV) or REVOLUTA (REV). Finally, we show that ATHB2 is part of a complex regulatory circuit directly involving both HD-Zip II and HD-Zip III proteins. Taken together, our study provides evidence that a genetic system consisting of HD-Zip II and HDZip III genes cooperates in establishing b ...
... PHAVOLUTA (PHV) or REVOLUTA (REV). Finally, we show that ATHB2 is part of a complex regulatory circuit directly involving both HD-Zip II and HD-Zip III proteins. Taken together, our study provides evidence that a genetic system consisting of HD-Zip II and HDZip III genes cooperates in establishing b ...
13_lecture_meiosis
... • A gamete (sperm or egg) contains a single set of chromosomes, and is haploid (n) • For humans, the haploid number is 23 (n = 23) • Each set of 23 consists of 22 autosomes and a single sex chromosome • In an unfertilized egg (ovum), the sex chromosome is X • In a sperm cell, the sex chromosome may ...
... • A gamete (sperm or egg) contains a single set of chromosomes, and is haploid (n) • For humans, the haploid number is 23 (n = 23) • Each set of 23 consists of 22 autosomes and a single sex chromosome • In an unfertilized egg (ovum), the sex chromosome is X • In a sperm cell, the sex chromosome may ...
Bacteroides mobilizable and conjugative genetic elements
... The repeated sequences bordering the erm genes of these three plasmids have been shown to be a related, if no identical, insertion sequence (IS) elements (IS4400 on pBFTM10, IS4351 on pBF4, and iso-IS4351 on pBI136). These flanking IS elements form compound transposons with their associated erm gene ...
... The repeated sequences bordering the erm genes of these three plasmids have been shown to be a related, if no identical, insertion sequence (IS) elements (IS4400 on pBFTM10, IS4351 on pBF4, and iso-IS4351 on pBI136). These flanking IS elements form compound transposons with their associated erm gene ...
Can my homozygous polled bull give me scurred calves?
... humans working them. For this reason calves with horns are discounted at the sale barn. Even though scurs pose no danger to other cattle or humans they are still discounted by many buyers. To avoid these discounts beef producers either have to breed them to be smooth polled or dehorn/de‐scur th ...
... humans working them. For this reason calves with horns are discounted at the sale barn. Even though scurs pose no danger to other cattle or humans they are still discounted by many buyers. To avoid these discounts beef producers either have to breed them to be smooth polled or dehorn/de‐scur th ...
Annotation mapping functions
... post.to corresponds directly to the from and to arguments in translate, with ”pre” for the translation before mapping and ”post” for the translation after mapping. In this example we used the org.Hs.eg.db to map the input from the symbol to Ensembl. As org.Hs.eg.db is centred around Entrez gene ids, ...
... post.to corresponds directly to the from and to arguments in translate, with ”pre” for the translation before mapping and ”post” for the translation after mapping. In this example we used the org.Hs.eg.db to map the input from the symbol to Ensembl. As org.Hs.eg.db is centred around Entrez gene ids, ...
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... Chromosomes (sSMC) are structurally abnormal chromosomes that cannot be identified or characterized by any of the routine cytogenetic banding techniques [13]. sSMC have been found for all chromosomes with different frequencies: about 30% are derived from chromosome 15, 20% from 22, 9% from 12, and o ...
... Chromosomes (sSMC) are structurally abnormal chromosomes that cannot be identified or characterized by any of the routine cytogenetic banding techniques [13]. sSMC have been found for all chromosomes with different frequencies: about 30% are derived from chromosome 15, 20% from 22, 9% from 12, and o ...
Loss And Gain Of Function Experiments Implicate TMEM18
... switched to a 45% fat diet (HFD) at 8 weeks of age. All mice were weighed weekly from weaning until 16 weeks of age. Female Tmem18tm1a homozygotes on a HFD showed no differences in body weight or body composition compared to wildtype littermates (Supplementary Fig 6B, D and F). However, male Tmem18t ...
... switched to a 45% fat diet (HFD) at 8 weeks of age. All mice were weighed weekly from weaning until 16 weeks of age. Female Tmem18tm1a homozygotes on a HFD showed no differences in body weight or body composition compared to wildtype littermates (Supplementary Fig 6B, D and F). However, male Tmem18t ...
Ch. 14 Mendel and the Gene Idea
... Situations of two or more genes 1. Epistasis gene at one location affects phenotypic expression of gene at a second location ex. black fur (B) is dominant over brown fur (b) for mouse to be brown = bb second gene determines whether pigment will be deposited in hair (C = dominant) if mouse is c ...
... Situations of two or more genes 1. Epistasis gene at one location affects phenotypic expression of gene at a second location ex. black fur (B) is dominant over brown fur (b) for mouse to be brown = bb second gene determines whether pigment will be deposited in hair (C = dominant) if mouse is c ...
A genetic screen in zebrafish identifies the mutants
... 1998; Pall and Jonas, 2005). However, with the exception of a few well-known cases, there is a wide chasm between the clinical and molecular understanding of these diseases. The power of zebrafish to study vertebrate development is well appreciated, and many disease models have emerged from studies ...
... 1998; Pall and Jonas, 2005). However, with the exception of a few well-known cases, there is a wide chasm between the clinical and molecular understanding of these diseases. The power of zebrafish to study vertebrate development is well appreciated, and many disease models have emerged from studies ...
Solutions for Chapter 3
... (c) Male with blood type B × Female with blood type A Again, the male with type B blood must be iBiB. A female with type A blood could have either the IAIA or IAiB genotypes. Since all of her kittens have type A blood, this suggests that she is homozygous for the for IA allele (IAIA) and only contri ...
... (c) Male with blood type B × Female with blood type A Again, the male with type B blood must be iBiB. A female with type A blood could have either the IAIA or IAiB genotypes. Since all of her kittens have type A blood, this suggests that she is homozygous for the for IA allele (IAIA) and only contri ...
Triple-hit lymphoma
... lymphoma was diagnosed using morphology, flow cytometry, immunochemistry, and cytogenetics. Since many triple-hit lymphomas have not been documented in the literature, it is important to bring attention to this entity, as this lymphoma has different prognostic and therapeutic implications than other ...
... lymphoma was diagnosed using morphology, flow cytometry, immunochemistry, and cytogenetics. Since many triple-hit lymphomas have not been documented in the literature, it is important to bring attention to this entity, as this lymphoma has different prognostic and therapeutic implications than other ...
The Chromosome Theory of Inheritance
... then separate to different gametes. Maternal and paternal copies of chromosome pairs separate without regard to the assortment of other homologous chromosome pairs. At fertilization an egg’s set of chromosomes unite with randomly encountered sperm’s chromosomes. In all cells derived from a fertilize ...
... then separate to different gametes. Maternal and paternal copies of chromosome pairs separate without regard to the assortment of other homologous chromosome pairs. At fertilization an egg’s set of chromosomes unite with randomly encountered sperm’s chromosomes. In all cells derived from a fertilize ...
Tissue- and Development-specific Expression of Multiple
... poorly understood. Recent reports of two alternative spliceforms of nNOS in the mouse and in man have raised the possibility of spatial and temporal modulation of expression. This study demonstrates the existence of at least three transcripts of the rat nNOS gene designated nNOSa, nNOSb, and nNOSc, ...
... poorly understood. Recent reports of two alternative spliceforms of nNOS in the mouse and in man have raised the possibility of spatial and temporal modulation of expression. This study demonstrates the existence of at least three transcripts of the rat nNOS gene designated nNOSa, nNOSb, and nNOSc, ...
A Novel Mouse Chromosome 17 Hybrid Sterility Locus
... within a M. spretus background causes sterility, however, the same combination of chromosome 17 homologs does not cause sterility within the M.domesticus background. This is a case of asymmetrical hybrid sterility. Through an analysis of recombinant chromosomes, it was possible to map the M. domesti ...
... within a M. spretus background causes sterility, however, the same combination of chromosome 17 homologs does not cause sterility within the M.domesticus background. This is a case of asymmetrical hybrid sterility. Through an analysis of recombinant chromosomes, it was possible to map the M. domesti ...
Julio`s MCB - Digital Access to Scholarship at Harvard
... morpholinos and cell sorting analysis in transgenic zebrafish embryos, we show that GATA-1 directly regulates the expression of Mfrn1. Mutagenesis of individual GATA-1 binding cis elements (GBE) demonstrated that at least two of the three GBE within this CRM are functionally required for GATA-mediat ...
... morpholinos and cell sorting analysis in transgenic zebrafish embryos, we show that GATA-1 directly regulates the expression of Mfrn1. Mutagenesis of individual GATA-1 binding cis elements (GBE) demonstrated that at least two of the three GBE within this CRM are functionally required for GATA-mediat ...
The B-cell maturation factor Blimp-1 specifies vertebrate slow
... Hh-regulated Gli proteins16 to activate the ubo promoter. To determine whether ubo is sufficient to drive cells down the pathway of slow-twitch fiber differentiation, we investigated the effects of its misexpression on the specification of muscle fiber identity. Transient misexpression of ubo driven ...
... Hh-regulated Gli proteins16 to activate the ubo promoter. To determine whether ubo is sufficient to drive cells down the pathway of slow-twitch fiber differentiation, we investigated the effects of its misexpression on the specification of muscle fiber identity. Transient misexpression of ubo driven ...
Autism and maternally derived aberrations of chromosome 15q
... [Ritvo et al., 1990; Folstein and Piven, 1991; Rutter et al., 1994]. The causes are heterogeneous, including genetic defects and environmental insults. In addition to the association of autism with specific heritable disorders (e.g., phenylketonuria and tuberous sclerosis), evidence for a genetic co ...
... [Ritvo et al., 1990; Folstein and Piven, 1991; Rutter et al., 1994]. The causes are heterogeneous, including genetic defects and environmental insults. In addition to the association of autism with specific heritable disorders (e.g., phenylketonuria and tuberous sclerosis), evidence for a genetic co ...