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Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates
Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates

... (from E. coli to D. radiodurans and Corynebacterium) of the genes encoding these precisely truncated GluRS fragments suggests that these proteins may have a yet unknown function. Nonetheless, GluX was not analyzed further. Class I lysyl-tRNA synthetase (LysRS) is structurally very related (27) and d ...
Genetic Characterization and Inheritance of Belly Spot
Genetic Characterization and Inheritance of Belly Spot

... In the cell wall of the melanocyte several proteins are attached, among them Kit, a transmembrane tyrosine kinase receptor. Kit has a ligand called Kitligand, steel or stem cell growth factor (SCF) (Alberts B. et al, 2002). From previous studies we know that Kit is involved in fetal development. The ...
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IlllllllllllllIlllllllIllllllllllllllIlllllllllllllllllllllllllllllllllllll

... and Bourgeois, supra), and is itself rapidly converted to chromosome to improve control of heterologous gene glucose and galactose. expression from a lac operated promoter (as long as a Another control element of the lac operon is catabo promoter is present to drive lacIZYA transcription). It lite r ...
A method for measuring the non-random bias of a codon usage table
A method for measuring the non-random bias of a codon usage table

... the result of some postulated impartial pattern of usage. The statistical test is quite general, and can, in principle, be used to measure any kind of unevenneas in the codon frequencies, comparing the observed frequencies with a predicted set, but in this paper we shall be mainly concerned with cod ...
Feline Genetics: a Combinatorial Approach - MTMK-ICF
Feline Genetics: a Combinatorial Approach - MTMK-ICF

... combinatorics of symbols, standing for genes. Please be warned that the mathematical models are aimed to explain the Mendel tables: the symbols may or may not correspond to real genes, and in all cases lead to oversimplification of the true biological complexity, which relies not only on principal g ...
Visualizing expression patterns of Shh and Foxf1 genes
Visualizing expression patterns of Shh and Foxf1 genes

... notochord, floor plate of the neural tube and polarizing region of the limbs [7]. It is involved in dorso-ventral foregut patterning [7, 8], presumably through notochord localization. The later expression of Shh in lung buds suggests that it plays a role in the morphogenesis of various epithelial ap ...
HLA imputation - BioMed Central
HLA imputation - BioMed Central

... Due to inherent differences between allele frequencies in the Ashkenazi and European populations, certain alleles of certain genes are over-called by imputation in Ashkenazi. These alleles were removed before association analysis was performed. For HLA-A plot below, the height of the colored bars o ...
Giant viruses, giant chimeras: The multiple evolutionary histories of
Giant viruses, giant chimeras: The multiple evolutionary histories of

... tree of life [7,10]. Moreover, there is compelling evidence for the polyphyletic origin of viruses, which further complicates the issue [11]. These debates have recently gained an unprecedented impetus when Raoult and co-workers published the description of the genome of Mimivirus, a giant virus fir ...
Evolution of the Actin Gene Family in Testate Lobose Amoebae
Evolution of the Actin Gene Family in Testate Lobose Amoebae

... Analyses of the resulting sequences reveal numerous diverse actin genes, which differ mostly by synonymous substitutions. We estimate that the actin gene family contains 40–50 paralogous members in each lineage. None of the three independent lineages share the same paralog with another, and divergen ...
here
here

... E: For example, it ignores the potential influence of environmental factors that may trigger or increase the risk of developing OCD, which is suggested by the diathesis-stress model. E: This is an issue because it has been found that over half the OCD patients in a study conducted by Cromer et al (2 ...
Control of GL2 expression in Arabidopsis leaves and trichomes
Control of GL2 expression in Arabidopsis leaves and trichomes

... GL2 protein appears to show celltype specific subcellular localization in developing leaves, and is localized in the nucleus in developing trichomes Both GL1 and TTG may directly bind to the GL2 promoter, either alone or as part of a larger complex, but the interaction between GL1 and R somehow elim ...
Evolutionary dynamics of nematode operons
Evolutionary dynamics of nematode operons

... genes reside in over 1100 operons in the model organism Caenorhabditis elegans. It is unclear how operons have become abundant in nematode genomes. The “one-way street” hypothesis asserts that once formed by chance, operons are very difficult to break, because the breakage would leave downstream gen ...
Genes and Genetic Testing in Hereditary Ataxias
Genes and Genetic Testing in Hereditary Ataxias

... The most common forms of dominant ataxias are caused by repeat expansion. Short repeats, typically three to six bases long, appear at variable repeat number within many genes. Occasionally these repeat regions become unstable during replication, leading to either deletions of repeats, which rarely c ...
Detachments from duplication bearing females
Detachments from duplication bearing females

... Furthermore, when detachments are produced, this region contains indeterminate and variable amounts of heterochromatin from both the attached-X and the other chromosome participating in the detachment process. A completely reasonable conclusion is that the detachments analyzed here differ in their b ...
QTL Mapping and Analysis for the Traits Related to Pod Dehiscence
QTL Mapping and Analysis for the Traits Related to Pod Dehiscence

... (2009) thought that qPDH1 controls the process of PD in soybean, while the morphological characteristics of soybean didn’t relate to this process. Yamada et al (2009) analyzed the PD among several soybean populations, and they found that there were differences among the PD controlling genes in diffe ...
1 Are the Eyes Homologous?
1 Are the Eyes Homologous?

... evolution (Kukalova-Peck, 1983) and wing venation patterns (KukalovaPeck, 1985). But we generally begin with the perception of similarity and then explain the similarities by appealing to a short list of possibilities. Biologists usually consider similarity to be the result of shared ancestry (homol ...
Recombination and epistasis facilitate introgressive hybridization
Recombination and epistasis facilitate introgressive hybridization

... affecting hybridization, because linkage equilibrium is recovered only by recombination, and it influences the efficacy of selection purging incompatible sets of exotic genes. As a modelling framework that ensures manipulation of recombination to examine the effect of recombination on introgressive ...
Genomics of adaptation and speciation in cichlid fishes: recent
Genomics of adaptation and speciation in cichlid fishes: recent

RT2 Profiler™ PCR Arrays: Pathway
RT2 Profiler™ PCR Arrays: Pathway

... or disease state. Wells H1 through H5 contain a panel of housekeeping genes (HK1-HK5) used for normalizing the PCR Array data. Well H6 contains a Genomic DNA Control (GDC) primer set that specifically detects non-transcribed, repetitive genomic DNA with a high level of sensitivity. Wells H7 through H ...
Updated slides on gene prediction
Updated slides on gene prediction

... Gene Prediction Analogy • Newspaper written in unknown language – Certain pages contain encoded message, say 99 letters on page 7, 30 on page 12 and 63 on page 15. • How do you recognize the message? You could probably distinguish between ads and other stories (ads contain the “$” sign often) • Stat ...
An organism containing a normal chromosome complement and
An organism containing a normal chromosome complement and

... Other aneuploids (i.e. primary trisomics, tetrasomics, multiple trisomics, secondary trisomics, tertiary trisomics, compensating trisomics) ...
The endogenous molecular clock orchestrates the temporal
The endogenous molecular clock orchestrates the temporal

... use is commonly linked with the fed/fasted and active/inactive behaviors, these changes in storage and use are also aligned with the 24-h (circadian) light/dark cycles attributed to the rising and setting of the sun and feeding/activity behavior [16]. At the core of circadian rhythms is a mechanism ...
Genome-wide analysis by SNP Array
Genome-wide analysis by SNP Array

... amplification, tagging and hybridisation on the Array slides. The BeadChips are then scanned using an iScan Reader (Illumina®) and the data analysis is performed using GenomeStudio and CaryoStudio (Illumina®). The BAF is the value between 0 and 1 and represents the proportion contribution of one SNP ...
SALIVARY GLAND CHROMOSOMES IN THE TWO RACES OF
SALIVARY GLAND CHROMOSOMES IN THE TWO RACES OF

... somewhat longer than suggested by the drawing. The scale below represents 30 micra. ...
Transfer of genetic material between the chloroplast and nucleus
Transfer of genetic material between the chloroplast and nucleus

... nuclear genome data reported that the plant nuclear genome is in equilibrium between frequent integration and rapid elimination of the chloroplast genome and that the pericentromeric regions play a significant role in facilitating the chloroplast–nuclear DNA flux. This equilibrium between integratio ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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