Recombination and the Frequency Spectrum in
... Parameters of the simulations were, for each locus, the sample size, the number of base pairs, and the population recombination rate C 5 Cmap (see below). Although our simulations are somewhat unorthodox, we refer to our set of assumptions as the ‘‘standard neutral model’’ (SNM). To implement the co ...
... Parameters of the simulations were, for each locus, the sample size, the number of base pairs, and the population recombination rate C 5 Cmap (see below). Although our simulations are somewhat unorthodox, we refer to our set of assumptions as the ‘‘standard neutral model’’ (SNM). To implement the co ...
Mapping QTLs for Popping Ability in a Popcorn × Dent Maize
... Popcorn is a unique line of flint corn with a dense, starchy interior and hard pericarp (exterior shell). The trait that distinguishes popcorn from other types of corn is its ability to form large flakes when heated (4). The popping ability of a popcorn kernel involves many heritable polygenic trait ...
... Popcorn is a unique line of flint corn with a dense, starchy interior and hard pericarp (exterior shell). The trait that distinguishes popcorn from other types of corn is its ability to form large flakes when heated (4). The popping ability of a popcorn kernel involves many heritable polygenic trait ...
Construction and Analysis of 2 Reciprocal Arabidopsis Introgression
... 2002). Once QTL have been identified for a trait under study, it becomes important to characterize and confirm the contributing individual loci (Koornneef et al. 1997). One of the most promising ways to do this is the use of introgression lines (ILs). Lines of an introgression library have a common ...
... 2002). Once QTL have been identified for a trait under study, it becomes important to characterize and confirm the contributing individual loci (Koornneef et al. 1997). One of the most promising ways to do this is the use of introgression lines (ILs). Lines of an introgression library have a common ...
genetic disorders associated with macrocephaly
... may occasionally be associated with hydrocephalus or true megalencephaly. Noonan syndrome is caused by mutations in the PTPN11 gene (12q24.1) in 50%, KRAS gene (12p12.1) in less than 5%, SOS1 gene (2p22-p21) in 10%, and RAF1 gene (3p25) in 3-17% of cases. Cardiofaciocutaneous (CFC) syndrome is chara ...
... may occasionally be associated with hydrocephalus or true megalencephaly. Noonan syndrome is caused by mutations in the PTPN11 gene (12q24.1) in 50%, KRAS gene (12p12.1) in less than 5%, SOS1 gene (2p22-p21) in 10%, and RAF1 gene (3p25) in 3-17% of cases. Cardiofaciocutaneous (CFC) syndrome is chara ...
Query Results
... Step 4: The user can choose to map the experimental tags against a subset of genomic tags upon a large amount of different features. For details see the help links or: Malig, R., Varela, C., Agosin, E. and Melo, F. (2006) Accurate and unambiguous tag-to-gene mapping in SAGE by a hierarchical gene a ...
... Step 4: The user can choose to map the experimental tags against a subset of genomic tags upon a large amount of different features. For details see the help links or: Malig, R., Varela, C., Agosin, E. and Melo, F. (2006) Accurate and unambiguous tag-to-gene mapping in SAGE by a hierarchical gene a ...
Morphology of nuclear transcription | SpringerLink
... control (McStay and Grummt 2008; Schlesinger et al. 2009; Shiao et al. 2011). The exact number and degree of variation in composition of individual repeats is largely unknown, mostly because molecular methods to analyze single repetitive elements in a genomic context have been missing. For HeLa cell ...
... control (McStay and Grummt 2008; Schlesinger et al. 2009; Shiao et al. 2011). The exact number and degree of variation in composition of individual repeats is largely unknown, mostly because molecular methods to analyze single repetitive elements in a genomic context have been missing. For HeLa cell ...
Stage-specific expressions of four different ribonuclease H genes in
... 1999). Amastigotes multiply in the macrophages and eventually lyse them. Leishmania and other related protozoa of the genus Trypanosoma (T. brucei and T. cruzi) are considered as primitive eukaryotes. Fortunately, although these early eukaryotes have many similarities in metabolic pathways and vital ...
... 1999). Amastigotes multiply in the macrophages and eventually lyse them. Leishmania and other related protozoa of the genus Trypanosoma (T. brucei and T. cruzi) are considered as primitive eukaryotes. Fortunately, although these early eukaryotes have many similarities in metabolic pathways and vital ...
video slide
... factor was affecting flower color in the F1 hybrids • Mendel called the purple flower color a dominant trait and the white flower color a recessive trait • Mendel observed the same pattern of inheritance in six other pea plant characters, each represented by two traits • What Mendel called a “herita ...
... factor was affecting flower color in the F1 hybrids • Mendel called the purple flower color a dominant trait and the white flower color a recessive trait • Mendel observed the same pattern of inheritance in six other pea plant characters, each represented by two traits • What Mendel called a “herita ...
Cancer Prone Disease Section Familial platelet disorder with predisposition to
... The role of RUNX1 in megakaryocytes is beginning to be revealed. In vitro studies suggest that RUNX1 participates in megakaryocyte lineage commitment and divergence from the erythroid pathway. While FPD/AML patients show a decrease in megakaryocyte colony growth, heterozygous or conditional bialleli ...
... The role of RUNX1 in megakaryocytes is beginning to be revealed. In vitro studies suggest that RUNX1 participates in megakaryocyte lineage commitment and divergence from the erythroid pathway. While FPD/AML patients show a decrease in megakaryocyte colony growth, heterozygous or conditional bialleli ...
What causes Autism Spectrum Disorder (ASD)?
... one child has an ASD, then the other will be affected between 36-95% of the time. In nonidentical twins, if one child has an ASD, then the other is affected between 0-31% of the time. The patterns of genetic inheritance are complex, with the involvement of multiple genes, rather than a simple domina ...
... one child has an ASD, then the other will be affected between 36-95% of the time. In nonidentical twins, if one child has an ASD, then the other is affected between 0-31% of the time. The patterns of genetic inheritance are complex, with the involvement of multiple genes, rather than a simple domina ...
Fulltext PDF - Indian Academy of Sciences
... basis of the allelic variation. Most early-flowering ecotypes carry FRI alleles that contain one of two different deletions that disrupt the open reading frame of the FRI gene. This suggests that loss-offunction mutations at FRI have provided the basis for the evolution of many early-flowering Arabi ...
... basis of the allelic variation. Most early-flowering ecotypes carry FRI alleles that contain one of two different deletions that disrupt the open reading frame of the FRI gene. This suggests that loss-offunction mutations at FRI have provided the basis for the evolution of many early-flowering Arabi ...
Intervention strategies for mitochondrial disease
... Mitochondrial biogenesis Increased expression of oxidative phosphorylation proteins A switch to a more glycolytic mode of ATP production Removal of dysfunctional mitochondria by quality-control systems The substrate supply, the mode of ATP generation, the level of demand for ATP, mitochondrial dynam ...
... Mitochondrial biogenesis Increased expression of oxidative phosphorylation proteins A switch to a more glycolytic mode of ATP production Removal of dysfunctional mitochondria by quality-control systems The substrate supply, the mode of ATP generation, the level of demand for ATP, mitochondrial dynam ...
Supplementary Legends - Word file
... displayed vigorous movements. In some cases we could obtain a result by performing ASS plus aster ablation. If both assays failed to give a result they are marked with a dash. We excluded genes from our analysis that failed in cytokinesis because of a missing furrow. If several genes acted in the sa ...
... displayed vigorous movements. In some cases we could obtain a result by performing ASS plus aster ablation. If both assays failed to give a result they are marked with a dash. We excluded genes from our analysis that failed in cytokinesis because of a missing furrow. If several genes acted in the sa ...
Animal breeding
... Fisher developed the analysis of variance (ANOVA). He had two fundamental insights. First, that parents do not pass on their entire genotypic value to their offspring, but rather pass along one of the two possible alleles at each locus. Hence, only part of G is passed on and thus we decompose G into ...
... Fisher developed the analysis of variance (ANOVA). He had two fundamental insights. First, that parents do not pass on their entire genotypic value to their offspring, but rather pass along one of the two possible alleles at each locus. Hence, only part of G is passed on and thus we decompose G into ...
P-Element Transformation with period Locus DNA Restores
... transformed flies carried only one dose of transduced per+ DNA (also, some of the flies we tested carried more than one dose, but were still long-period; see Experimental Procedures). We do not have enough molecular information to interpret the apparently subnormal activity of the two rescuing DNA s ...
... transformed flies carried only one dose of transduced per+ DNA (also, some of the flies we tested carried more than one dose, but were still long-period; see Experimental Procedures). We do not have enough molecular information to interpret the apparently subnormal activity of the two rescuing DNA s ...
Fifteen years of genomewide scans for selection: trends, lessons
... convergence of natural selection on a subset of molecular targets might result from something other than a true biological bias towards a subset of critical proteins. For example, apparent biological bias may result from inability to detect unusual modes or targets of selection, failure to correct f ...
... convergence of natural selection on a subset of molecular targets might result from something other than a true biological bias towards a subset of critical proteins. For example, apparent biological bias may result from inability to detect unusual modes or targets of selection, failure to correct f ...
File - interACT - American College of Toxicology
... Zhejiang University in Hangzhou, China, and received her Ph.D. Degree with honors in University of Kansas Medical Center. Julia currently is an Assistant Professor in Toxicology in the Department of Environmental and Occupational Health Sciences. She is a recipient of the Sheldon D. Murphy Endowed C ...
... Zhejiang University in Hangzhou, China, and received her Ph.D. Degree with honors in University of Kansas Medical Center. Julia currently is an Assistant Professor in Toxicology in the Department of Environmental and Occupational Health Sciences. She is a recipient of the Sheldon D. Murphy Endowed C ...
Genome-Wide Copy Number Variation in Epilepsy: Novel
... some cases, the epilepsy has a clear cause such as an abnormality in the brain or a head injury. However, in many cases there is no obvious cause. Numerous studies have shown that genetic factors are important in these types of epilepsy, but although several epilepsy genes are known, we can still on ...
... some cases, the epilepsy has a clear cause such as an abnormality in the brain or a head injury. However, in many cases there is no obvious cause. Numerous studies have shown that genetic factors are important in these types of epilepsy, but although several epilepsy genes are known, we can still on ...
Full Text
... can act to induce anterior neural structures in the mouse. Tam and colleagues have shown that the AVE fails to induce anterior neural tissue when grafted laterally in the egg cylinder and will only do so when more posterior tissue is included in the graft(Tam and Steiner, 1999). Similarly, we have s ...
... can act to induce anterior neural structures in the mouse. Tam and colleagues have shown that the AVE fails to induce anterior neural tissue when grafted laterally in the egg cylinder and will only do so when more posterior tissue is included in the graft(Tam and Steiner, 1999). Similarly, we have s ...
Analysis of skin color change and related gene
... The Dongxiang black chicken is one of 107 Chinese domestic chickens recorded in “Animal Genetic Resources in China: Poultry” (China National Commision of Animal Genetic Resources, 2011). The bird is characterized by its black feathers, and its comb, beak, skin, muscle, bone, tibia, and toe are almos ...
... The Dongxiang black chicken is one of 107 Chinese domestic chickens recorded in “Animal Genetic Resources in China: Poultry” (China National Commision of Animal Genetic Resources, 2011). The bird is characterized by its black feathers, and its comb, beak, skin, muscle, bone, tibia, and toe are almos ...
1st set of Journal Clubs this Wednesday!
... 1. There are two key control elements of the operon: the repressor gene and the operator to which the repressor gene product binds. 2. There is a specific interaction between the inducer and repressor that prevents the repressor from binding to the operator. 3. All three lac genes are clustered unde ...
... 1. There are two key control elements of the operon: the repressor gene and the operator to which the repressor gene product binds. 2. There is a specific interaction between the inducer and repressor that prevents the repressor from binding to the operator. 3. All three lac genes are clustered unde ...
Comparative Metagenomic Analysis Reveals Mechanisms for Stress
... from the GeoChip database (Tu et al. 2014). Only genes related to stress response, including genes that belong to any one of five functional ‘stress’ categories: temperature, osmolarity, oxidative stress and oxygen limitation, nutrient limitation, and protein stress, were retrieved. These gene famil ...
... from the GeoChip database (Tu et al. 2014). Only genes related to stress response, including genes that belong to any one of five functional ‘stress’ categories: temperature, osmolarity, oxidative stress and oxygen limitation, nutrient limitation, and protein stress, were retrieved. These gene famil ...
Gene Section RAD52 (RAD52 homolog (S. cerevisiae)) Atlas of Genetics and Cytogenetics
... important for the binding with ssDNA by RAD52 (Hays et al., 1998; Shinohara et al., 1998; Jackson et al., 2002). hRAD52 binds directly to DSBs, protects them from exonuclease resection, and facilitates end-to-end interaction (Van Dyck et al., 1999). Furthermore, capture of the second DNA end in homo ...
... important for the binding with ssDNA by RAD52 (Hays et al., 1998; Shinohara et al., 1998; Jackson et al., 2002). hRAD52 binds directly to DSBs, protects them from exonuclease resection, and facilitates end-to-end interaction (Van Dyck et al., 1999). Furthermore, capture of the second DNA end in homo ...
HOM-C/Hox genes and four interacting loci
... (Fig. 1D). They are necessary for copulation. As the rays differ from each other, there is further axial patterning within the tail region (Fig. 1E). Each ray comprises the dendritic endings of two neurons and a support cell. The ends of the rays are located at reproducible positions in the cuticle, ...
... (Fig. 1D). They are necessary for copulation. As the rays differ from each other, there is further axial patterning within the tail region (Fig. 1E). Each ray comprises the dendritic endings of two neurons and a support cell. The ends of the rays are located at reproducible positions in the cuticle, ...