Table 2
... BAV, and according to linkage analysis, mutations in the same genes probably caused some cases of hypoplastic left heart syndrome and BAV (9). One possible interpretation of these observations is that LVOT morphology and obstruction may also influence aortic valve development because of alterations i ...
... BAV, and according to linkage analysis, mutations in the same genes probably caused some cases of hypoplastic left heart syndrome and BAV (9). One possible interpretation of these observations is that LVOT morphology and obstruction may also influence aortic valve development because of alterations i ...
Andrew Phillips
... Perform in silico experiments on biological system models Use these to formulate testable hypotheses for experimentation in vivo ...
... Perform in silico experiments on biological system models Use these to formulate testable hypotheses for experimentation in vivo ...
The Breast Cancer Polygene and Longevity Genes: The Implications
... carriers buying more insurance than low risk polygenotype carriers in a critical illness insurance market open to females between ages 20–60. Screening available for the polygene only. . . . . . . . . . . . . . . . . Costs of adverse selection resulting from low risk polygenotype carriers buying les ...
... carriers buying more insurance than low risk polygenotype carriers in a critical illness insurance market open to females between ages 20–60. Screening available for the polygene only. . . . . . . . . . . . . . . . . Costs of adverse selection resulting from low risk polygenotype carriers buying les ...
"Nitrogen Fixation: 1888-2001"
... called heterocysts e.g. Anabaena PCC7120 or Nostoc punctiforme and nonheterocystous organisms such as Gloeothece. When species such as Anabaena are deprived of a source of fixed nitrogen about every tenth vegetative cell in the cyanobacterial filament differentiates into a morphologically and physio ...
... called heterocysts e.g. Anabaena PCC7120 or Nostoc punctiforme and nonheterocystous organisms such as Gloeothece. When species such as Anabaena are deprived of a source of fixed nitrogen about every tenth vegetative cell in the cyanobacterial filament differentiates into a morphologically and physio ...
Potential virulence and antimicrobial susceptibility of
... comprises 14 species, although its taxonomy remains confusing [2]. Aeromonas popo¤i is one of the most recently described species, and only a few strains have been recovered up to now [3,4]. In an extensive study carried out in our laboratory, some strains showed an atypical biochemical behavior [5] ...
... comprises 14 species, although its taxonomy remains confusing [2]. Aeromonas popo¤i is one of the most recently described species, and only a few strains have been recovered up to now [3,4]. In an extensive study carried out in our laboratory, some strains showed an atypical biochemical behavior [5] ...
PersPecTIves - Ralf Sommer
... One reverse genetics technology that has been used extensively in evo–devo in recent years to overcome technical limitations is RNAi. Although RNAi is becoming increasingly accessible, it is not easily transferable to every organism, and even in C. elegans, in which it was originally described, it d ...
... One reverse genetics technology that has been used extensively in evo–devo in recent years to overcome technical limitations is RNAi. Although RNAi is becoming increasingly accessible, it is not easily transferable to every organism, and even in C. elegans, in which it was originally described, it d ...
In vivo evidence for the prokaryotic model of extended codon
... deleted (lane 2). Apart from these controls, the results showed that the ectopic expression of either the WT-A37, U37 or G37 tRNAfMet (lanes 4±8) had no general effect on chloroplast translation rates, probably because of the presence of an equal or greater amount of the WT tRNAfMet transcribed from ...
... deleted (lane 2). Apart from these controls, the results showed that the ectopic expression of either the WT-A37, U37 or G37 tRNAfMet (lanes 4±8) had no general effect on chloroplast translation rates, probably because of the presence of an equal or greater amount of the WT tRNAfMet transcribed from ...
Distinguishing genotype and phenotype in genetic programming
... is that the behaviour of a GA system (and GA is taken here to include GP as a particular case) depends greatly on the way the genotypes represent the phenotypes. Thus, we should expect some change in performance to result from a change of design. Whether the change is for the better or worse is only ...
... is that the behaviour of a GA system (and GA is taken here to include GP as a particular case) depends greatly on the way the genotypes represent the phenotypes. Thus, we should expect some change in performance to result from a change of design. Whether the change is for the better or worse is only ...
Clinical and Molecular Aspects of Diseases of Mitochondrial DNA
... to DNA, was significantly less than the mtDNA copy number. In humans, mt-nucleoids are about 0.068 µm in diameter as judged from immunocytochemical staining, and the mitochondrial genome per nucleoid is estimated to be between 2 and 10 copies.(38,39) In S cerevisiae, mt-nucleoids are larger than hum ...
... to DNA, was significantly less than the mtDNA copy number. In humans, mt-nucleoids are about 0.068 µm in diameter as judged from immunocytochemical staining, and the mitochondrial genome per nucleoid is estimated to be between 2 and 10 copies.(38,39) In S cerevisiae, mt-nucleoids are larger than hum ...
channel 1 gene dosage
... In mature mammalian muscle, the muscular chloride channel ClC-1 contributes about 75% of the sarcolemmal resting conductance (Gm). In mice carrying two defective alleles of the corresponding CIcl gene, chloride conductance (Gci) is reduced to less than 10 % of that of wild-type, and this causes hype ...
... In mature mammalian muscle, the muscular chloride channel ClC-1 contributes about 75% of the sarcolemmal resting conductance (Gm). In mice carrying two defective alleles of the corresponding CIcl gene, chloride conductance (Gci) is reduced to less than 10 % of that of wild-type, and this causes hype ...
pdf
... is unclear what circumstances caused this relatively rapid speciation and migrations of these taxa (The Yeti sample, we are told, comes from the mountains of Nepal, while the Leprechaun seems to exist primarily in Ireland). But Bogeyreta is the most taxon-rich monophyletic group encountered so far, ...
... is unclear what circumstances caused this relatively rapid speciation and migrations of these taxa (The Yeti sample, we are told, comes from the mountains of Nepal, while the Leprechaun seems to exist primarily in Ireland). But Bogeyreta is the most taxon-rich monophyletic group encountered so far, ...
Somatic sex-determining signals act on XX germ cells in Drosophila
... branched fusomes, we have used 2C1, an antibody that visualizes these structures (Zaccai and Lipshitz, 1996; and Fig. 1E,F). Blue mgm1-expressing cells, which were radially arranged around the unstained somatic hub cells, possessed small sherical dots (Fig. 1G,H). Elongated and branched fusome struc ...
... branched fusomes, we have used 2C1, an antibody that visualizes these structures (Zaccai and Lipshitz, 1996; and Fig. 1E,F). Blue mgm1-expressing cells, which were radially arranged around the unstained somatic hub cells, possessed small sherical dots (Fig. 1G,H). Elongated and branched fusome struc ...
The genomic landscape of meiotic crossovers and gene
... Sequencing and genotyping of meiotic tetrads We constructed F1 hybrids of the A. thaliana accessions Columbia (Col) and Landsberg erecta (Ler) in the quartet1 (qrt1) −/− background (Preuss et al., 1994) and crossed individual pollen tetrads to a male sterile EMS mutant of the Cape Verde Island (Cvi) ...
... Sequencing and genotyping of meiotic tetrads We constructed F1 hybrids of the A. thaliana accessions Columbia (Col) and Landsberg erecta (Ler) in the quartet1 (qrt1) −/− background (Preuss et al., 1994) and crossed individual pollen tetrads to a male sterile EMS mutant of the Cape Verde Island (Cvi) ...
View/Open
... including peritonitis, pleuritis, arthritis, and transient inflammatory responses. The genetic analysis of MEFV gene was approved by the Ethics Committee of Nagasaki Medical Center, and written informed consent was obtained from each individual. On the basis of Tel-Hashomer criteria [13], we divided ...
... including peritonitis, pleuritis, arthritis, and transient inflammatory responses. The genetic analysis of MEFV gene was approved by the Ethics Committee of Nagasaki Medical Center, and written informed consent was obtained from each individual. On the basis of Tel-Hashomer criteria [13], we divided ...
A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. PLoS Genetics 7: e1002087.
... FGF, which activates Breathless FGFR and plays a central role in controlling and coupling each of these processes by guiding outgrowth of primary branches and inducing expression of key genes encoding transcription factors such as pointed, blistered/pruned, and escargot required, respectively, for s ...
... FGF, which activates Breathless FGFR and plays a central role in controlling and coupling each of these processes by guiding outgrowth of primary branches and inducing expression of key genes encoding transcription factors such as pointed, blistered/pruned, and escargot required, respectively, for s ...
Mutations affecting the cardiovascular system and other internal
... (Kern et al., 1995), perhaps due to redundancy. In fact, the disruption of the retinoic acid receptors (RAR) α, β or γ individually do not result in any obvious phenotypes, but the compound mutations show severe defects in various organs, including the cardiovascular system (Mendelsohn et al., 1994) ...
... (Kern et al., 1995), perhaps due to redundancy. In fact, the disruption of the retinoic acid receptors (RAR) α, β or γ individually do not result in any obvious phenotypes, but the compound mutations show severe defects in various organs, including the cardiovascular system (Mendelsohn et al., 1994) ...
GENETICS: Introduction
... the queen's ancestor or relatives were affected, it seems that the RECESSIVE allele she carried arose by mutation either in Queen Victoria or one of her parents. Her daughters Alice and Beatrice were carriers and introduced the allele into the ruling houses of Russia and Spain. Alexis, the last heir ...
... the queen's ancestor or relatives were affected, it seems that the RECESSIVE allele she carried arose by mutation either in Queen Victoria or one of her parents. Her daughters Alice and Beatrice were carriers and introduced the allele into the ruling houses of Russia and Spain. Alexis, the last heir ...
Databases_what_and_w..
... come from the DNA via RNA. • Changes in DNA cause changes in proteins. • Changes in proteins cause changes in phenotypes. ...
... come from the DNA via RNA. • Changes in DNA cause changes in proteins. • Changes in proteins cause changes in phenotypes. ...
Small Nucleolar RNA
... • Enzymes likely evolved from gene duplications of tRNA or rRNA processing enzymes • Ancestral snoRNAs likely guided these enzymes and acquired specificities for novel rRNA sites ...
... • Enzymes likely evolved from gene duplications of tRNA or rRNA processing enzymes • Ancestral snoRNAs likely guided these enzymes and acquired specificities for novel rRNA sites ...
Patel, Sohum (2017) Could Sickle Cell Anaemia save your life?
... In its efforts to communicate the paradoxical nature of heterozygote advantage, this paper will refer to sickle cell anaemia and malaria, two ostensibly unrelated conditions; one a blood disorder, the other an infectious disease, but whose fates have been intertwined with one another through the cen ...
... In its efforts to communicate the paradoxical nature of heterozygote advantage, this paper will refer to sickle cell anaemia and malaria, two ostensibly unrelated conditions; one a blood disorder, the other an infectious disease, but whose fates have been intertwined with one another through the cen ...
csirnetugcdec
... This is copyrighted material of Genesis Academy meant only for personal use, any reproduction in a book or any other material will be require prior permission from Genesis Academy. ...
... This is copyrighted material of Genesis Academy meant only for personal use, any reproduction in a book or any other material will be require prior permission from Genesis Academy. ...
Oliver, B., Kim, Y.-J., and Baker, B. S.
... this end, our initial experiments address whether the sexspecific functioning of Sxl in the germ line is regulated by alternative pre-mRNA processing as it is in the soma. A finding that Sxl+ produces sex-specific transcripts within the germ line enables us to use these sex-specific transcripts as a ...
... this end, our initial experiments address whether the sexspecific functioning of Sxl in the germ line is regulated by alternative pre-mRNA processing as it is in the soma. A finding that Sxl+ produces sex-specific transcripts within the germ line enables us to use these sex-specific transcripts as a ...
Solved paper CSIR NET Life Science December
... This is copyrighted material of Genesis Academy meant only for personal use, any reproduction in a book or any other material will be require prior permission from Genesis Academy. ...
... This is copyrighted material of Genesis Academy meant only for personal use, any reproduction in a book or any other material will be require prior permission from Genesis Academy. ...
CHROMOSOMES AND DISEASE
... males may have three (48,XXXY) or four (49,XXXXY) X chromosomes. About 80% of boys with Klinefelter syndrome will have 47,XXY in all cells of the body. About 6% will show a normal chromosome complement i.e. 46,XY in some cells and 46,XXY in the others (mosaicism). In 5% of cases there is a 46,XX/47, ...
... males may have three (48,XXXY) or four (49,XXXXY) X chromosomes. About 80% of boys with Klinefelter syndrome will have 47,XXY in all cells of the body. About 6% will show a normal chromosome complement i.e. 46,XY in some cells and 46,XXY in the others (mosaicism). In 5% of cases there is a 46,XX/47, ...