glo-3, a novel Caenorhabditis elegans gene, is required for lysosome
... 15(n484), and unc-27(e159). Glo non-Dpy, Glo non-Egl, or Glo non-Unc F2 progeny of this cross were isolated. Single Dpy, Egl, or Unc progeny were selected from the next generation and should be glo double mutants. At least two independent double mutant lines were isolated from each cross, and in all ...
... 15(n484), and unc-27(e159). Glo non-Dpy, Glo non-Egl, or Glo non-Unc F2 progeny of this cross were isolated. Single Dpy, Egl, or Unc progeny were selected from the next generation and should be glo double mutants. At least two independent double mutant lines were isolated from each cross, and in all ...
Mutations at the Darkener of apricot Locus Modulate Transcript
... segregants in the F1 generation. Since the Bx locus is X amounts, and Doa heteroallelic flies the most. Other linked, F, males were hemizygous for Bx'~,and females were Bx alleles similarly tested (Bx-a B104 element, BxZheterozygous for wild-type and Bxf6 alleles. Similar tests an insertion of dual ...
... segregants in the F1 generation. Since the Bx locus is X amounts, and Doa heteroallelic flies the most. Other linked, F, males were hemizygous for Bx'~,and females were Bx alleles similarly tested (Bx-a B104 element, BxZheterozygous for wild-type and Bxf6 alleles. Similar tests an insertion of dual ...
The Isolation of Mutagen-Sensitive nuv Mutants of
... thedeterminations were carriedout as two large experiments, one for sensitivity to M N N G and the other for sensitivity to 4 - N Q O , in which all the plates at a particular mutagen concentration were made up using the same mutagen-containing media. This was necessary due to the inherent instabili ...
... thedeterminations were carriedout as two large experiments, one for sensitivity to M N N G and the other for sensitivity to 4 - N Q O , in which all the plates at a particular mutagen concentration were made up using the same mutagen-containing media. This was necessary due to the inherent instabili ...
The-NOS-problem
... contained a lesion in the NOS (Nitric oxide synthase) locus that was shown to weaken NOS activity, which led them to conclude that NOS function is essential. Yakubovich et al., however, came up with evidence supporting that the lethality in NOSC was due not to the lesion within the NOS locus, but wa ...
... contained a lesion in the NOS (Nitric oxide synthase) locus that was shown to weaken NOS activity, which led them to conclude that NOS function is essential. Yakubovich et al., however, came up with evidence supporting that the lethality in NOSC was due not to the lesion within the NOS locus, but wa ...
Apical-basal pattern formation in the Arabidopsis
... Although the ‘oblong’ seedling lacks both cotyledons and root, it seems to have an axis as indicated not only by its shape but also by the distribution of vascular cells which are not localised as a compact group but scattered along the axis (not shown). By this criterion, the ‘oblong’ seedling repr ...
... Although the ‘oblong’ seedling lacks both cotyledons and root, it seems to have an axis as indicated not only by its shape but also by the distribution of vascular cells which are not localised as a compact group but scattered along the axis (not shown). By this criterion, the ‘oblong’ seedling repr ...
THE GENETICS AND REPRODUCTIVE ISOLATING MECHANISMS
... light bryonix can be found. The most important genetic results were obtained from the cross "III" which could be brought up to the 14th generation without introduction of any new bryonix blood, but with 7 refreshments of outdoor nopi. The recent analysis of these crossings confirmed the author's pre ...
... light bryonix can be found. The most important genetic results were obtained from the cross "III" which could be brought up to the 14th generation without introduction of any new bryonix blood, but with 7 refreshments of outdoor nopi. The recent analysis of these crossings confirmed the author's pre ...
Genetic linkage studies in the pseudoautosomal
... only exceptions are the gametes, which are produced by the sex organs (testes and ovaries). Gametes are produced by a special form of cell division called meiosis. Two chromosomes are said to be homologous if they pair (synapse) during meiosis. Two homologous chromosomes are not only similar in leng ...
... only exceptions are the gametes, which are produced by the sex organs (testes and ovaries). Gametes are produced by a special form of cell division called meiosis. Two chromosomes are said to be homologous if they pair (synapse) during meiosis. Two homologous chromosomes are not only similar in leng ...
BAM Receptors Regulate Stem Cell Specification and Organ
... bam2-1, clv1-7 bam2-1, clv1-11 bam2-1, clv2-1 bam2-1, clv3-2 bam21, clv1-7 bam1-3, clv1-11 bam1-3, clv1-7 bam2-3, and clv1-11 bam23 double-mutant combinations were generated by crossing plants homozygous for the bam1-1, bam2-1, bam1-3, or bam2-3 allele to plants homozygous for the respective clv1, c ...
... bam2-1, clv1-7 bam2-1, clv1-11 bam2-1, clv2-1 bam2-1, clv3-2 bam21, clv1-7 bam1-3, clv1-11 bam1-3, clv1-7 bam2-3, and clv1-11 bam23 double-mutant combinations were generated by crossing plants homozygous for the bam1-1, bam2-1, bam1-3, or bam2-3 allele to plants homozygous for the respective clv1, c ...
Base-pair neutral homozygotes can be discriminated by calibrated
... For our MSH2 (49 bp), PAH (59 bp), CHK2 (42 bp) and BX647987 (58 bp) small amplicons, nearest neighbor analysis predicted Tm differences of 0.198C, 0.188C, 0.318C and 0.048C, respectively, between amplicons containing alternative homozygotes. For our CPS1 and OTC PCR products, nearest neighbor analys ...
... For our MSH2 (49 bp), PAH (59 bp), CHK2 (42 bp) and BX647987 (58 bp) small amplicons, nearest neighbor analysis predicted Tm differences of 0.198C, 0.188C, 0.318C and 0.048C, respectively, between amplicons containing alternative homozygotes. For our CPS1 and OTC PCR products, nearest neighbor analys ...
Käfer, E. and D. Luk
... Non-complementing pairs were further checked for recombination in intercrosses. However, since the latter were often sterile, most mutants were simultaneously crossed to alcoy; csp-2 (FGSC 3434) and mapped further to linked markers (Table 1). They were routinely checked for fertility in homozygous c ...
... Non-complementing pairs were further checked for recombination in intercrosses. However, since the latter were often sterile, most mutants were simultaneously crossed to alcoy; csp-2 (FGSC 3434) and mapped further to linked markers (Table 1). They were routinely checked for fertility in homozygous c ...
On algebraic properties of the human ABO
... (sex cells) which carry a single set of chromosomes. A parent with blood group O produces gametes with alleles O. A parent with blood group AB produces gametes with alleles A or B. A parent with blood group A produces gametes with alleles A or O if his genotype is OA, and only A if it is of AA. When ...
... (sex cells) which carry a single set of chromosomes. A parent with blood group O produces gametes with alleles O. A parent with blood group AB produces gametes with alleles A or B. A parent with blood group A produces gametes with alleles A or O if his genotype is OA, and only A if it is of AA. When ...
A gain of function mutation causing skeletal overgrowth in the
... Fig. 2. Cloning of rapunzelc14. (A) A meiotic map representing approximately 47 kb of the rapunzelc14 region on chromosome 16. The critical region contains three paralogous genes (rpz, rpz2 and rpz3). Two additional paralogues (rpz4 and rpz5) are also present on chromosome 16, outside of the critica ...
... Fig. 2. Cloning of rapunzelc14. (A) A meiotic map representing approximately 47 kb of the rapunzelc14 region on chromosome 16. The critical region contains three paralogous genes (rpz, rpz2 and rpz3). Two additional paralogues (rpz4 and rpz5) are also present on chromosome 16, outside of the critica ...
ABO Blood Group System
... The ABO Blood Group System was the first to be identified and is the most significant for transfusion practice It is the ONLY system that the reciprocal antibodies are consistently and predictably present in the sera of people who have had no exposure to human red cells ...
... The ABO Blood Group System was the first to be identified and is the most significant for transfusion practice It is the ONLY system that the reciprocal antibodies are consistently and predictably present in the sera of people who have had no exposure to human red cells ...
PDF
... binding) and an N-terminal, signal peptide (that is required for paracrine secretion) with the prototypical members, FGF1 and 2 (Ornitz and Itoh 2001). During embryonic and fetal development of the mouse, Fgf5 is first expressed in the extraembryonic ectoderm of the epiblast and then restricted to d ...
... binding) and an N-terminal, signal peptide (that is required for paracrine secretion) with the prototypical members, FGF1 and 2 (Ornitz and Itoh 2001). During embryonic and fetal development of the mouse, Fgf5 is first expressed in the extraembryonic ectoderm of the epiblast and then restricted to d ...
the genetics of the golden-winged x blue
... the throat-patch and the white or yellow of the underparts to the action, respectively, of two single genes. In the case of throat-patch inheritance, this seemsto be correct. Inheritance of underparts color, however, does not involve simple presence- or absence-characterssuch as those determining co ...
... the throat-patch and the white or yellow of the underparts to the action, respectively, of two single genes. In the case of throat-patch inheritance, this seemsto be correct. Inheritance of underparts color, however, does not involve simple presence- or absence-characterssuch as those determining co ...
Single-Nucleotide Polymorphism Mapping
... We have found that the easiest way to analyze interval mapping SNP data is to put the data into a simple spreadsheet, with a row for each singled plate (the F2 generation) and a column for each SNP. It is helpful to color each cell depending on the genotype (N2, CB4856, or heterozygote) by using the ...
... We have found that the easiest way to analyze interval mapping SNP data is to put the data into a simple spreadsheet, with a row for each singled plate (the F2 generation) and a column for each SNP. It is helpful to color each cell depending on the genotype (N2, CB4856, or heterozygote) by using the ...
Genome-Wide Identification of Allelic Expression in Hypertensive
... Genomic SSLP data were available for 2 SHR lines (SHR/OlaHsd and SHRSP/Riv) and 1 WKY line (WKY/OlaHsd). These lines are closely related to, and may be identical to, the SHR/NCrl, SHR-A3, and WKY/NCrl lines, respectively, used in our studies. We used this data to assess the degree of allelic identit ...
... Genomic SSLP data were available for 2 SHR lines (SHR/OlaHsd and SHRSP/Riv) and 1 WKY line (WKY/OlaHsd). These lines are closely related to, and may be identical to, the SHR/NCrl, SHR-A3, and WKY/NCrl lines, respectively, used in our studies. We used this data to assess the degree of allelic identit ...
Genome-Wide Identification of Allelic Expression in Hypertensive Rats
... Genomic SSLP data were available for 2 SHR lines (SHR/OlaHsd and SHRSP/Riv) and 1 WKY line (WKY/OlaHsd). These lines are closely related to, and may be identical to, the SHR/NCrl, SHR-A3, and WKY/NCrl lines, respectively, used in our studies. We used this data to assess the degree of allelic identit ...
... Genomic SSLP data were available for 2 SHR lines (SHR/OlaHsd and SHRSP/Riv) and 1 WKY line (WKY/OlaHsd). These lines are closely related to, and may be identical to, the SHR/NCrl, SHR-A3, and WKY/NCrl lines, respectively, used in our studies. We used this data to assess the degree of allelic identit ...
final pop & Eco test on Oct 21st
... This was for 20 on Mixed Bag (from reproduction): strawberry, fern, or cattails board ...
... This was for 20 on Mixed Bag (from reproduction): strawberry, fern, or cattails board ...
Role of tumor necrosis factor alpha gene polymorphism in childhood
... Bronchial asthma is a common disease with multiple determinants that include genetic variation, environmental exposures, and gene–environment interactions. Tumor necrosis factor alpha (TNF-α) has a role in asthma and wheezing pathophysiology. Single nucleotide gene polymorphisms, may be important as ...
... Bronchial asthma is a common disease with multiple determinants that include genetic variation, environmental exposures, and gene–environment interactions. Tumor necrosis factor alpha (TNF-α) has a role in asthma and wheezing pathophysiology. Single nucleotide gene polymorphisms, may be important as ...
Fulltext PDF - Indian Academy of Sciences
... the observation that ts paralytic / lethal trans heterozygous adults showed weaker paralysis than their respective ts paralytic homozygotes (Chandrashekaran and Sarla 1993). The paralytic phenotypes of the 32 possible viable / lethal heteroallelic and four homoallelic combinations of stmA are shown ...
... the observation that ts paralytic / lethal trans heterozygous adults showed weaker paralysis than their respective ts paralytic homozygotes (Chandrashekaran and Sarla 1993). The paralytic phenotypes of the 32 possible viable / lethal heteroallelic and four homoallelic combinations of stmA are shown ...
Genetics WWTBAM 1
... carrier of the recessive haemophilia gene, which is sex-linked. What proportion of their offspring could have the condition? ...
... carrier of the recessive haemophilia gene, which is sex-linked. What proportion of their offspring could have the condition? ...
Dominance (genetics)
Dominance in genetics is a relationship between alleles of one gene, in which the effect on phenotype of one allele masks the contribution of a second allele at the same locus. The first allele is dominant and the second allele is recessive. For genes on an autosome (any chromosome other than a sex chromosome), the alleles and their associated traits are autosomal dominant or autosomal recessive. Dominance is a key concept in Mendelian inheritance and classical genetics. Often the dominant allele codes for a functional protein whereas the recessive allele does not.A classic example of dominance is the inheritance of seed shape, for example a pea shape in peas. Peas may be round, associated with allele R or wrinkled, associated with allele r. In this case, three combinations of alleles (genotypes) are possible: RR, Rr, and rr. The RR individuals have round peas and the rr individuals have wrinkled peas. In Rr individuals the R allele masks the presence of the r allele, so these individuals also have round peas. Thus, allele R is dominant to allele r, and allele r is recessive to allele R. This use of upper case letters for dominant alleles and lower caseones for recessive alleles is a widely followed convention.More generally, where a gene exists in two allelic versions (designated A and a), three combinations of alleles are possible: AA, Aa, and aa. If AA and aa individuals (homozygotes) show different forms of some trait (phenotypes), and Aa individuals (heterozygotes) show the same phenotype as AA individuals, then allele A is said to dominate or be dominant to or show dominance to allele a, and a is said to be recessive to A.Dominance is not inherent to an allele. It is a relationship between alleles; one allele can be dominant over a second allele, recessive to a third allele, and codominant to a fourth. Also, an allele may be dominant for a particular aspect of phenotype but not for other aspects influenced by the same gene. Dominance differs from epistasis, a relationship in which an allele of one gene affects the expression of another allele at a different gene.