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Chapter_16_Review_Game
Chapter_16_Review_Game

... A male is heterozygous for the trait that produces freckles on the skin, and he has freckles. If he marries a woman who is also heterozygous for freckles, ______ percent of their children will be freckled and __________ percent of their children will 38% ...
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Sex-Linked Inheritance
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Name - Humble ISD

... b. Individuals that are SS produce abnormal hemoglobin that causes the red blood cells to “sickle” when oxygen availability is decreased; i. for example, in high altitudes or during periods of stress. Sickled RBCs are more fragile, easily destroyed – results in lack of ____________ due to decreased ...
HGEN: Chapters 2, 5 and 6 Study Guide Test on TUESDAY, 10/15
HGEN: Chapters 2, 5 and 6 Study Guide Test on TUESDAY, 10/15

... CHROMATIN: UNCOILED DNA; present when the cell isn’t dividing. CHROMOSOMES: COILED DNA; present when the cell is performing mitosis. SISTER CHROMATIDS: joined together by centromere; matching alleles at same place HOMOLOGOUS CHROMOSOMES: Chromosomes that are of the same size, shape, information, and ...
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Skewed X-inactivation

Skewed X chromosome inactivation occurs when the inactivation of one X chromosome is favored over the other, leading to an uneven number of cells with each chromosome inactivated. It is usually defined as one allele being found on the active X chromosome in over 75% of cells, and extreme skewing is when over 90% of cells have inactivated the same X chromosome. It can be caused by primary nonrandom inactivation, either by chance due to a small cell pool or directed by genes, or caused by secondary nonrandom inactivation, which occurs by selection. Most females will have some levels of skewing. It is relatively common in adult females; around 35% of women have skewed ratio over 70:30, and 7% of women have an extreme skewed ratio of over 90:10. This is of medical significance due to the potential for the expression of disease genes present on the X chromosome that are normally not expressed due to random X inactivation. X chromosome inactivation occurs in females to provide dosage compensation between the sexes. If females kept both X chromosomes active they would have twice the number of active X genes than males, who only have one copy of the X chromosome. At approximately the time of implantation (see Implantation (human embryo), one of the two X chromosomes is randomly selected for inactivation. The cell undergoes transcriptional and epigenetic changes to ensure this inactivation is permanent. All progeny from these initial cells will maintain the inactivation of the same chromosome, resulting in a mosaic pattern of cells in females.
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