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Gene Therapy and Animal Models for Retinal Disease
Gene Therapy and Animal Models for Retinal Disease

... researchers to develop genetically engineered models that either overexpress genes known to lead to retinal disease or disrupt normal retinal gene function. These animals continue to expand our understanding of basic retinal biology and help to unravel the mysteries surrounding mechanisms of retina ...
Bitemporal Hemianopia Caused by Retinal Disease
Bitemporal Hemianopia Caused by Retinal Disease

... We describe a patient with a nonprogressive bitemporal hemianopia caused not by optic chiasmal dysfunction but by retinal disease that was diagnosed by multifocal electroretinography (mfERG) after results from neuroimaging studies were repeatedly normal. Report of a Case. A 67-year-old woman with a ...
Spectral Domain Optical Coherence Tomography Imaging of Retinal
Spectral Domain Optical Coherence Tomography Imaging of Retinal

... in the SD-OCT yielded more information than similar depictions on TD-OCT. The localization capability of the crosshairs of SD-OCT was useful in locating lesions across an area of imaged retina and could be used in conjunction with angiographic findings. There was improved patient cooperation with SD ...
outline25083
outline25083

... - Cholesterol deposits (Hollenhorst plaques), Tamoxifen , Canthaxanthine (oral tanning agent), calcific drusen Workup of Talc Retinopathy - Fluorescein angiography if neovscularization is suspect - Lung x-ray and lung function tests 10. Optociliary Shunts from Optic Nerve Sheath Meningioma Masquerad ...
Acute Visual Loss
Acute Visual Loss

...  Central/ branch retinal artery occlusion  Central/ branch retinal vein occlusion ...
INTRODUCTION - Downloadmela
INTRODUCTION - Downloadmela

... stability (in buffered saline solution) is excellent even for periods as long as 2 years. In vivo, however, the passivation layer could withstand the biological environment for up to about six months only. In contrast, the electrodes made of titanium nitride showed excellent biostability over more t ...
Visual Pathways
Visual Pathways

... Func*on  of  V1:  Bring  together  informa7on  for  the  two  eyes  and  reorganize  the   inputs  so  that  cells  respond  best  to  oriented  lines.   ...
AN EXPLANATION OF EYE DISEASE by Gayle Kaye, edited by
AN EXPLANATION OF EYE DISEASE by Gayle Kaye, edited by

... degeneration of the cells of the retina and can result in complete blindness. “PRA”, or rod-cone dysplasia type 2 (rcd2), is a form of retinal degeneration that has been in collies for decades. In this disease, an abnormal development (dysplasia) and then rapid degeneration of the rods and cones (th ...
Retinal Degeneration: Proof of Principal, Medical Therapy and
Retinal Degeneration: Proof of Principal, Medical Therapy and

... Available for Testing: • For example, Dr. Sahel et al. have shown the Rod-derived Cone Viability Factor (RdCVF) is a potent agent that promotes cone cell viability. Cone cells are the most important type of photoreceptor cell since they are used in central, sharp and color vision. • Dr. LaVail and o ...
sympathetic ophthalmia - M.M.Joshi Eye Institute
sympathetic ophthalmia - M.M.Joshi Eye Institute

... •Streilein JW (ed): Immune Response and the Eye. Chem Immunol. Basel, Karger, 1999, vol 73. ...
Pathophysiology.of.retinal.vein.occlusion
Pathophysiology.of.retinal.vein.occlusion

... It is likely that the sudden retinal ischemia that occurs in BRVO and more so in CRVO will induce excessive VEGF production. VEGF is produced by the retina from retinal pigment epithelial cells, endothelial cells, and Muller cells, as well as other types of ocular tissue.22 Boyd et al found a close ...
He cries crocodile tears . . .
He cries crocodile tears . . .

... maximum length of 5-6 metres and weighing as much as two Sumo wrestlers (between 800–1000 lb (364–455 kg)), this species is important to the biodiversity and ecology of the area, but may also offer us an unintended glimpse into our evolutionary past by looking through their eyes. The crocodilians, r ...
Research Summaries for Faculty Trainers
Research Summaries for Faculty Trainers

... in protein-protein interactions with a concentration on the plexin and the Eph-A1 and Eph-B1 transmembrane receptors. Protein interactions determine the basic mechanisms by which proteins transmit signals in cells and how signaling is disrupted by mutation in diseased states. Knowing at near-atomic ...
vocab review unit 4 sensation and perception
vocab review unit 4 sensation and perception

... • information processing guided by higherlevel mental processes, as when we construct perceptions drawing on our experience and expectations. ...
Ocular Health Assessment Options
Ocular Health Assessment Options

... technology that captures more than 80% of your retina in one panoramic image while traditional imaging methods typically only show 15% of your retina at one time. The unique Optomap ultra-wide field view helps your eye care practitioner detect early signs of retinal disease more effectively and effi ...
Repair of Primary Rhegmatogenous Retinal Detachment
Repair of Primary Rhegmatogenous Retinal Detachment

... retinopexy, scleral buckle, and vitrectomy for larger retinal detachments. Vitreous surgery with or without scleral buckle is usually the obvious choice for complex retinal detachments involving factors such as giant retinal tear, large and/or postequatorial retinal breaks, vitreous hemorrhage, macu ...
29 - Alamo Colleges
29 - Alamo Colleges

... Excitation of Cones  Visual pigments in cones are similar to rods ...
Resolution of Mid-Peripheral Intraretinal Fluid in X
Resolution of Mid-Peripheral Intraretinal Fluid in X

... treatment. This likely occurs in other patients with XLRS who have been treated with carbonic anhydrase inhibitors, but it remains unappreciated if the midperipheral region is not scanned with SDOCT. ...
tibodies cross-reacting with patho- gens expressed by carcinoma cells. Cancer-associated retinopathy with
tibodies cross-reacting with patho- gens expressed by carcinoma cells. Cancer-associated retinopathy with

... have systemic benign tumors.4 The patient we describe was diagnosed as having CAR with antirecoverin antibody 11 years after the initial visual symptoms appeared despite clinical features resembling AIR. Our group previously described a patient with CAR who had aberrant expression of recoverin in ma ...
Vision research special issue: Sight restoration: Prosthetics
Vision research special issue: Sight restoration: Prosthetics

... 2014). Although blind individuals now have more tools and opportunities than ever before (see Fig. 1), learning the skills required to be a functional blind individual, especially late in life, remains a daunting task. This special issue is inspired by the wide variety of innovative approaches that ...
document
document

... of their vision. Duration of visual loss ranges from only a few seconds to a few hours depending on the aetiology of the vision loss. Eg. Obscured vision due to papilledema may last only seconds, while a severely atherosclerotic carotid artery may be associated with duration of one to ten minutes. ...
Visual field organization and retinal resolution
Visual field organization and retinal resolution

... (Mass & Supin, 1997; Murayama et al., 1992). The only exception was the Amazon River dolphin, Inia geoffrensis, (family Iniidae) (Mass & Supin, 1989). Thus, data presented herein confirm that the retinal topography with two high-resolution areas is a common property of most cetaceans, independent of ...
A microscopic study of herpes simplex virus retinopathy in mice.
A microscopic study of herpes simplex virus retinopathy in mice.

... Prior to virus inoculation, mice were anesthetized with a 0.02 ml intramuscular injection of a 1:1 mixture of xylazine (20 mg/ml) and ketamine (100 mg/ml). A 27-gauge needle was used to make an incision at the limbus of the left eye of each mouse under microscopic visualization. A glass micropipette ...
212 IS THE CHROMATIC PUPILLARY RESPONSE (CPR) A
212 IS THE CHROMATIC PUPILLARY RESPONSE (CPR) A

... the pineal gland. Recent information show that intrinsically photosensitive retinal ganglion cells (ipRGCs), using the photopigment melanopsin, respond directly to light to drive pupillary constriction. These cells project and innervate the superior colliculus and dorsal lateral geniculate nucleus, ...
retina outline: part 1 - UAB School of Optometry
retina outline: part 1 - UAB School of Optometry

... photoreceptors and have inhibitory outputs back onto photoreceptors. Blue cones are a major source of input onto H2 horizontal cells.  Amacrine cells—a class of retinal interneurons that make connections in the inner plexiform layer among bipolar, ganglion and other ganglion cells (30 types) AII am ...
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Retinal waves

Retinal waves are spontaneous bursts of action potentials that propagate in a wave-like fashion across the developing retina. These waves occur before rod and cone maturation and before vision can occur. The signals from retinal waves drive the activity in the dorsal lateral geniculate nucleus (dLGN) and the primary visual cortex. The waves are thought to propagate across neighboring cells in random directions determined by periods of refractoriness that follow the initial depolarization. Retinal waves are thought to have properties that define early connectivity of circuits and synapses between cells in the retina. There is still much debate about the exact role of retinal waves; some contend that the waves are instructional in the formation of retinogeniculate pathways, while others argue that the activity is necessary, but not instructional in the formation of retinogeniculate pathways.
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